Guesthouse holiday rentals in Greenville County

Find and book unique guesthouse rentals on Airbnb

Top-rated Guesthouses in Greenville County

Guests agree: These guesthouses are highly rated for location, cleanliness and more.

1 of 1 pages1 / 1

Top Guest favourite

A bright living area features a comfortable sofa and an armchair, both adorned with coordinating decorative pillows. Soft lighting is provided by two lamps on accent tables. Large windows allow natural light to fill the space, complementing the floral-patterned curtains.

Guesthouse in Greenville

4.97 out of 5 average rating, 135 reviews

The Spring Valley Retreat

Newly renovated in 2021, very comfortable guesthouse located in a quiet neighborhood just 10 minutes from downtown Greenville. Created by highly experienced bed and breakfast owners, this space is carefully crafted to be a relaxing, restful place for travelers. Two bedrooms, a kitchen with brand-new appliances, dining area, smart TV, a desktop space, WiFi, and an outdoor porch spot to enjoy nice weather days. Note that if you search the address on Google, it will pull up photos before renovation

ValueLocationGetting around

Top Guest favourite

A charming log cabin is nestled among lush greenery, featuring wooden walls and a sloping roof. The front door is framed by two windows adorned with flower boxes. Two white chairs sit on a stone pathway, inviting relaxation in the serene outdoor setting.

Guesthouse in Greenville

4.93 out of 5 average rating, 750 reviews

Historic 19th Century Cabin/Guest House

This 19th century cabin is your perfect cozy getaway. This guest house is located on a 3.5 acre property, secluded from the historic neighborhood, though it's just 3 miles from downtown Greenville and the Bon Secours Wellness Arena. Less than a mile to the Swamp Rabbit Trail, this cottage is perfect for jaunts to downtown Greenville, Furman University, Paris Mountain, Travelers Rest and Unity Park! Micro weddings and events are available upon request and approval with applicable fees applied.

FamilyLocationCleanliness

Guest favourite

Guesthouse in Greenville

4.8 out of 5 average rating, 357 reviews

Cozy Cottage Minutes from DT, Furman, SR trail, TR

My 50's cottage is charming and cozy, renovated bath and kitchen, very clean and convenient to downtown, Traveler's Rest & Furman University. Located in a quiet space with parking right beside the cottage. We are a straight shot to downtown Greenville in about 7 minutes. I listen to my awesome guests and have made a few recent updates: new electrical outlets in bathroom, new larger hot water heater for longer showers and now a Kitchen is equipped with a cusinart oven, induction top/microwave

ValueLocationOutdoor spaces

Top Guest favourite

The serene cottage is surrounded by lush greenery and colorful flowers, with pink azaleas and white dogwoods blooming prominently in the foreground. A charming red barn is nestled among the trees, enhancing the peaceful rural setting.

Guesthouse in Greenville

4.99 out of 5 average rating, 465 reviews

The Cottage at Old Oaks Farm

Built in the early 1900's, this serene cottage is located approximately one mile from Furman University at the base of Paris Mt. It has been lovingly improved, but the floors are a bit slanted and no corner is exactly square. Located in a neighborhood on a five acre farm, it consists of three large rooms, comfortably furnished and lots of natural light. The cottage is convenient to downtown Greenville(5 miles),Travelers Rest, Furman, and the Swamp Rabbit Trail. No pet fee or cleaning fee.

ValueLocationSleep quality

Top Guest favourite

An archway leads to a narrow passage, flanked by white brick walls, with exposed brick adding texture. Warm lighting from overhead fixtures illuminates the space. On the ground, patterned red and brown bricks create a welcoming path, complemented by decorative lanterns placed nearby.

Guesthouse in Greenville

4.95 out of 5 average rating, 254 reviews

Gorgeous Downtown Studio & Dog Friendly!

This has changed to a minimum of a 3 month rental! Message me if you're trying to book and your dates aren't showing available! This location is unmatched. Steps from Falls Park which includes one of the most majestic waterfalls, green space and Swamp Rabbit Trail for all your running/walking and biking needs. Directly across the street from the Greenville Drive baseball stadium. One block from all the finest restaurants, shopping and best attractions downtown offers.

LocationValueParking

Top Guest favourite

A charming cottage is positioned next to a swimming pool, featuring a sloped roof and large windows. Lush greenery surrounds the area, providing a natural feel. The pool deck is paved, with a diving board extending into the clear water, creating an inviting outdoor space.

Guesthouse in Greenville

4.98 out of 5 average rating, 286 reviews

Greenville With A View!

ONLY 10-15 MINUTE DRIVE TO THE HEART OF BEAUTIFUL DOWNTOWN GREENVILLE! We are only 11 miles to GSP Airport; 6 miles to Greenville Downtown Airport; and 10 minutes to the Swamp Rabbit Trail. We are minutes to Furman University, Bob Jones University, North Greenville University and Clemson University is only 45 minutes away. We are tucked away open top of Paris Mountain. If you want to bike, hike, paddle, swim, boat or just soak it all in, start here!

ValueFamilyOutdoor spaces

Top Guest favourite

A studio space features a kitchenette with hanging cookware, a small dining table with two chairs, and natural wood flooring. Natural light fills the area through a window with wooden trim, while rustic brick accents create a cozy feel. A spacious bed is adorned with a neutral-colored blanket.

Guesthouse in Travelers Rest

4.99 out of 5 average rating, 114 reviews

The Dwelling Place: Just a mile from downtown TR

The Dwelling Place was created for guests to enjoy Travelers Rest and the beautiful surrounding areas. It is a studio apartment above a detached garage with a private entrance and driveway. We are a one minute walk from the Swamp Rabbit Trail, a 1.2 mile walk from the idyllic downtown Travelers Rest, 20 min. from Greenville, 8 min. from Furman, 15 min. from North Greenville University, and close to numerous hikes, waterfalls, and outdoor adventures!

ValueLocationLayout

Top Guest favourite

The kitchen showcases modern stainless steel appliances and warm wooden cabinetry. An island with seating invites gatherings, while ample counter space is available for meal preparation. Natural light fills the area through the window, enhancing the inviting atmosphere.

Guesthouse in Taylors

4.97 out of 5 average rating, 149 reviews

Just off Main near Taylors Mill - Clean & Comfy

You will be Located in the heart of Taylors, SC just off Historic Main St. and a stones throw from where the original train depot once was. This beautiful and Clean 1150 sq ft, updated, two bedroom, two bath (ensuite) second floor guest house with back patio area set on over two acres is centrally located to Greenville, Spartanburg and surrounding areas. Close to so many conveniences. Perfect for longer stays! 15min to Downtown.

ValueLocationAmenities

Top Guest favourite

The exterior of the property is shown, featuring yellow siding complemented by dark shutters on the windows. A single door with glass panels is visible, providing a welcoming entrance. A grassy area is located at the base of the wall, enhancing the outdoor setting.

Guesthouse in Liberty

4.93 out of 5 average rating, 218 reviews

Holly Hideaway! 10 Highway miles to Clemson U!

Holly Hideaway is nestled between Greenville and Clemson, in the small town of Liberty. It's perfect for business travelers, couples, Clemson parents, alumni, and small families. Tiled throughout for cleanliness. Privacy, tranquility, and clean, comfortable accommodations are what we provide. We are 10 minutes from Clemson and 3 miles from SWU. The Hideaway now offers Wi-Fi and Smart TV.

FamilyValueQuiet

Guest favourite

The exterior view of the Shou-Sugi-Ban Guest House features a dark wooden facade with a sloped roof. A spacious deck is present, furnished with two orange chairs and a potted plant. Lush greenery surrounds the area, providing a natural feel.

Guesthouse in Piedmont

4.98 out of 5 average rating, 142 reviews

Shou-Sugi-Ban Retreat on the Saluda River

The Shou-Sugi-Ban Guest House is 5 miles from Greenville city center and West Greenville, yet you'll feel like you've escaped it all with the rush of the river and surrounding trees. This cozy, custom space has a king-size bed, and two sets of French doors leading out to a private deck. No matter where you are in the space, you'll have views of the 700 ft of Saluda river frontage.

FamilyLocationEV charging

Top Guest favourite

A charming cottage is set among lush greenery, featuring a spacious deck that extends from the front. Large windows provide natural light, while surrounding trees and plants create a serene atmosphere.

Guesthouse in Greenville

5.0 out of 5 average rating, 192 reviews

Sally's Cottage

Couples retreat located 6 miles from downtown Greenville and the Swamp Rabbit Trail in a comfortable country setting. Wake up to a beautiful woods view through a large bay window and wildlife that surrounds the cottage (deer, birds and squirrels). Experience the beauty of the country in the city! Enjoy the eclectic collection of art and design in this cute little cottage.

ValueLocationBackyard

Guest favourite

The exterior of a modern detached guest house is illuminated at night, featuring large windows and a welcoming porch with two chairs. Soft lighting enhances the architectural lines, while greenery and a wooden fence create a peaceful outdoor environment.

Guesthouse in Travelers Rest

4.95 out of 5 average rating, 146 reviews

Modern guesthouse in downtown TR

Steps from the Swamp Rabbit Trail, Tandem Coffee, Topsoil and more! Enjoy a stylish, relaxed stay at our centrally-located place. Whether you're an outdoor enthusiast or fun-loving foodie, you'll find something just for you nearby. Only a short drive to downtown Greenville, Furman University or Paris Mountain. Within an hour drive of Asheville and Clemson University!

LocationFamilyView