
Lake house holiday rentals in Greenville
Find and book unique lakehouses on Airbnb
Top-rated lakehouse rentals in Greenville
Guests agree: These lakehouses are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for Greenville lakehouse rentals
Waterfront lakehouse rentals

Evergreen Lakes | Mountain Cabin | Gorgeous Views

Good Times @ Clemson / Lake Hartwell

Keowee Key Luxury Condo - Stunning Views!

Lakefront Mid-Century Dream Home / 3 mi to Clemson

Emerald Shore

Harry's Hideaway

Waterfront*Sunrise*Big Porch*Fire Pit*Tryon*TIEC

Sunset Cottage -Waterfront with Kayaks
Pet-friendly lake house rentals

Lakeview House: Hike, Relax, Mountain Bike & More!

Lakefront Escape

Sleeps 8 | Firepit | Hot Tub | Private Lake Access

Tryon: Mountain Views, Lake & Hot tub

Lake Bowen Retreat

Hailey’s Lake House with Pool and Hot Tub.

Napoli family lake house. Our home is your home.

Lake Keowee Hideaway Lake Access in a Private Cove
Private lake house rentals

Lake Home & Treehouse ❤ Seneca Treehouse Project

Swaying Oaks Lakeside Retreat

Large lake house - 15 min to Downtown Greenville

Golf Course Oasis: Pool* Tennis* Pklball* Hot Tub*

Clean and Cozy Connestee Falls Mountain House

Cedar Creek Oasis in Sunset, SC

Lake Keowee Home near Clemson, boating, and hiking

Entire home with 3 docks on Hartwell near Clemson
Destinations to explore
- Pigeon Forge Holiday rentals
- Asheville Holiday rentals
- Upstate South Carolina Holiday rentals
- Augusta Holiday rentals
- Sevierville Holiday rentals
- Atlanta Holiday rentals
- Nashville Holiday rentals
- Gatlinburg Holiday rentals
- Charleston Holiday rentals
- Western North Carolina Holiday rentals
- Myrtle Beach Holiday rentals
- Charlotte Holiday rentals
- Cabin rentals Greenville
- Fitness-friendly rentals Greenville
- Kid-friendly rentals Greenville
- Family-friendly rentals Greenville
- Rentals with a patio Greenville
- Rentals with a hot tub Greenville
- Guesthouse rentals Greenville
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- Pet-friendly rentals Greenville
- Apartment rentals Greenville
- Rentals with pools Greenville
- Cottage rentals Greenville
- Rentals with a fireplace Greenville
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- Rentals with a fire pit Greenville
- Condo rentals Greenville
- Private suite rentals Greenville
- Rentals with a washing machine and dryer Greenville
- Rentals with an EV charger Greenville
- House rentals Greenville
- Lakehouse rentals South Carolina
- Yurt Rentals United States
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- Cabin Rentals Australia
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- Holiday Chalets United Kingdom
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- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Blue Ridge Parkway
- Table Rock State Park
- Lake Lure Beach and Water Park
- Tugaloo State Park
- Gorges State Park
- The North Carolina Arboretum
- Mountaintop Golf & Lake Club
- Jump Off Rock
- Chimney Rock State Park
- Old Edwards Club
- Wade Hampton Golf Club
- Ski Sapphire Valley
- Vineyards for Biltmore Winery
- Discovery Island
- Carl Sandburg Home National Historic Site
- Victoria Valley Vineyards
- Haas Family Golf
- Biltmore Forest County Club