Guesthouse holiday rentals in Greenville

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Top-rated Guesthouses in Greenville

Guests agree: These guesthouses are highly rated for location, cleanliness and more.

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Top Guest favourite

Guesthouse in Greenville

4.98 out of 5 average rating, 109 reviews

The Spring Valley Retreat

Newly renovated in 2021, very comfortable guesthouse located in a quiet neighborhood just 10 minutes from downtown Greenville. Created by highly experienced bed and breakfast owners, this space is carefully crafted to be a relaxing, restful place for travelers. Two bedrooms, a kitchen with brand-new appliances, dining area, smart TV, a desktop space, WiFi, and an outdoor porch spot to enjoy nice weather days. Note that if you search the address on Google, it will pull up photos before renovation

Top Guest favourite

Guesthouse in Greenville

4.93 out of 5 average rating, 691 reviews

Historic 19th Century Cabin/Guest House

This 19th century cabin is your perfect cozy getaway. This guest house is located on a 3.5 acre property, secluded from the historic neighborhood, though it's just 3 miles from downtown Greenville and the Bon Secours Wellness Arena. Less than a mile to the Swamp Rabbit Trail, this cottage is perfect for jaunts to downtown Greenville, Furman University, Paris Mountain, Travelers Rest and Unity Park! Micro weddings and events are available upon request and approval with applicable fees applied.

Top Guest favourite

Guesthouse in Greenville

4.97 out of 5 average rating, 127 reviews

Nishleigh's Nook - West End Downtown Greenville

Welcome to your cozy retreat in the West End of Downtown Greenville! This newly constructed, detached garage studio near the up and coming West End Village, Unity Park, and downtown offers easy access to the city's best entertainment, boutique shops, and vibrant food scene. Enjoy a queen-sized memory foam bed, a fully equipped kitchen, and a dedicated dining area. High-speed Wi-Fi and a smart TV are included. Perfect for a peaceful escape with all the comforts you need for a memorable stay.

Top Guest favourite

Guesthouse in Greenville

5 out of 5 average rating, 431 reviews

The Cottage at Old Oaks Farm

Built in the early 1900's, this serene cottage is located approximately one mile from Furman University at the base of Paris Mt. It has been lovingly improved, but the floors are a bit slanted and no corner is exactly square. Located in a neighborhood on a five acre farm, it consists of three large rooms, comfortably furnished and lots of natural light. The cottage is convenient to downtown Greenville(5 miles),Travelers Rest, Furman, and the Swamp Rabbit Trail. No pet fee or cleaning fee.

Top Guest favourite

Guesthouse in Campobello

4.97 out of 5 average rating, 128 reviews

Bungalow on a 3 acre mini farm

This is a tree house like bungalow in beautiful Campobello SC. Enjoy a peaceful, rural retreat that is central to Upstate SC and Western NC. We are about 5 miles to downtown Landrum SC, 25 minutes to Spartanburg SC, 40 minutes to Greenville SC, 45 minutes to Asheville NC, and about 22 minutes to the Tryon Equestrian Center in NC. Inside the unit, downstairs is the kitchen, dining area, and bathroom, Upstairs in the loft are 4 different beds (Queen, Three Singles) &.a common area.

Top Guest favourite

Guesthouse in Greenville

4.94 out of 5 average rating, 219 reviews

Gorgeous Downtown Studio & Dog Friendly!

This has moved to 30 days+ starting Jan 2024! Message me if you're trying to book and your dates aren't showing available! This location is unmatched. Steps from Falls Park which includes one of the most majestic waterfalls, green space and Swamp Rabbit Trail for all your running/walking and biking needs. Directly across the street from the Greenville Drive baseball stadium. One block from all the finest restaurants, shopping and best attractions downtown offers.

Top Guest favourite

Guesthouse in Greenville

4.98 out of 5 average rating, 254 reviews

Greenville With A View!

ONLY 10-15 MINUTE DRIVE TO THE HEART OF BEAUTIFUL DOWNTOWN GREENVILLE! We are only 11 miles to GSP Airport; 6 miles to Greenville Downtown Airport; and 10 minutes to the Swamp Rabbit Trail. We are minutes to Furman University, Bob Jones University, North Greenville University and Clemson University is only 45 minutes away. We are tucked away open top of Paris Mountain. If you want to bike, hike, paddle, swim, boat or just soak it all in, start here!

Top Guest favourite

Guesthouse in Inman

4.99 out of 5 average rating, 136 reviews

Foothills Favorite

Custom designed 1 bedroom suite in the Lake Bowen/Landrum/Inman area. Comfortable yet sleek space tucked above a semi-detached garage; private entry & stairway to suite. Private deck overlooks green spaces, wooded area & Lake Bowen (best views late fall and winter). Enjoy mountain views at nearby Lake Bowen park, local wineries, and scenic highways. Minutes from Landrum & Tryon & Equestrian Center.

Guest favourite

Guesthouse in Piedmont

4.98 out of 5 average rating, 113 reviews

Shou-Sugi-Ban Retreat on the Saluda River

The Shou-Sugi-Ban Guest House is 5 miles from Greenville city center and West Greenville, yet you'll feel like you've escaped it all with the rush of the river and surrounding trees. This cozy, custom space has a king-size bed, and two sets of French doors leading out to a private deck. No matter where you are in the space, you'll have views of the 700 ft of Saluda river frontage.

Top Guest favourite

Guesthouse in Greenville

5 out of 5 average rating, 146 reviews

Sally's Cottage

Couples retreat located 6 miles from downtown Greenville and the Swamp Rabbit Trail in a comfortable country setting. Wake up to a beautiful woods view through a large bay window and wildlife that surrounds the cottage (deer, birds and squirrels). Experience the beauty of the country in the city! Enjoy the eclectic collection of art and design in this cute little cottage.

Guest favourite

Guesthouse in Mauldin

4.89 out of 5 average rating, 218 reviews

Cozy Pet-Friendly Home | Near Greenville & I-85

You’ll love staying here because it’s the perfect mix of comfort, privacy, and charm. Whether you’re relaxing by the fire pit, enjoying the peaceful outdoor space, or unwinding inside with all the comforts of home, this cozy retreat offers everything you need for a relaxing and memorable stay. Plus, it’s pet-friendly and located in a quiet neighborhood close to everything!

Guest favourite

Guesthouse in Travelers Rest

4.96 out of 5 average rating, 131 reviews

Modern guesthouse in downtown TR

Steps from the Swamp Rabbit Trail, Tandem Coffee, Topsoil and more! Enjoy a stylish, relaxed stay at our centrally-located place. Whether you're an outdoor enthusiast or fun-loving foodie, you'll find something just for you nearby. Only a short drive to downtown Greenville, Furman University or Paris Mountain. Within an hour drive of Asheville and Clemson University!