
Family-friendly holiday rentals in Little Italy
Find and book unique family-friendly homes on Airbnb
Quick stats about holiday rentals that are family-friendly in Little Italy

Total holiday rentals
Explore 180 holiday rentals in Little Italy

Nightly prices starting at
Little Italy holiday rentals start at $152 NZD per night before taxes and fees

Verified guest reviews
Over 14,910 verified reviews to help you choose

Pet-friendly accommodation
Find 70 rentals that welcome pets

Holiday rentals with a pool
40 properties feature pools

Rentals with dedicated workspaces
120 properties have a dedicated workspace

Wi-Fi availability
180 of Little Italy holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Little Italy rentals

4.8 Average rating
Little Italy stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated family-friendly rentals in Little Italy
Guests agree: These family-friendly homes are highly rated for location, cleanliness and more.

Contemporary, Fully Renovated Loft in Little Italy
Book this spectacular contemporary loft with 25 foot ceilings & views! The loft is in an area with a 9.8/10 walk score & known for having the best restaurants, bars &shops. The unit is newly renovated & meticulously designed with bright windows, contemporary high-end furnishings & an everyday spa inspired bathroom. Only steps from the waterfront, you decide if you want to enjoy cocktails & cuisine in the night scene or relax all day walking along the harbor. Free parking spot with access to all.

BEST LOCATION in all of Little Italy & downtown!
Location, location, location! Can't get any closer to the bustling Little Italy area in downtown San Diego. San Diego's best restaurants and nightlife in your backyard. One of the only houses in all of downtown! This modern luxury home is just blocks from the waterfront and a short Uber or walk to the Gaslamp, Convention Center & San Diego Zoo! All the frills: ++ Prime location! 98/100 Walker Score rating ++ High-speed internet, Netflix & smart TV ++ A/C ++ Super Host 5-star service

Calm Luxury Penthouse Getaway With Panoramic Views
Welcome to the most relaxing and luxurious penthouse condo in Little Italy! Featuring 2 expansive balconies with sweeping views, my condo sleeps 4-6 comfortably and is situated right in the heart of San Diego's most desirable neighborhood, Little Italy. Enjoy an area that is rich in exquisite cuisine, boutiques, patio cafés, exciting bars and local breweries. Area amenities nearby feature the famous San Diego Zoo, beautiful Balboa Park, Waterfront Park, the Convention Center and much more!

Chic Inner City Pad w/ Balcony | Walk Everywhere!
Stay right in the heart of vibrant Little Italy in this contemporary, inner-city apt with quaint piazzas and upscale boutiques all right on your doorstep. Split over two levels the apt features a thoughtfully curated design with living/dining on the lower level and an open double bedroom upstairs which steps out onto a balcony. Leave the car behind and walk to cocktail bars, brewpubs and restaurants or drive with downtown, the Gaslamp Quarter and Mission Beach only a short Uber ride away.

Artifact Inn - Historic Deluxe Studio in Downtown
The Artifact Inn professionally managed by NOVIQ. Unwind with ease in this chic Gaslamp studio offering a queen bed, air mattress, Smart TV, and free WiFi. Cook meals in the full kitchen, refresh with in-unit laundry, and enjoy climate control with central AC. With thoughtful touches and professional cleaning, this stylish retreat provides both comfort and security. Perfectly situated near Petco Park and top attractions, it’s ideal for those seeking a central and vibrant San Diego escape.

Gorgeous 2Bd Corner Bungalow in Little Italy
Little Italy Bungalows are located in the heart of San Diego’s most popular restaurant and entertainment district, Little Italy. Just one block from India Street, Farmer’s Market, and minutes from downtown, Balboa Park, airport, and harbor & beaches. This is a delightful neighborhood, steeped in local history and culture, and popular for dining and exploring. Little Italy Bungalows is perfect for couples, families, business travelers, convention-goers, single travelers and adventurers.

City View Banker's Hill
A beautifully renovated 2-bedroom, 1.5-bathroom craftsman-style duplex is perfectly situated in the heart of Bankers Hill. The perfect blend of classic craftsmanship and modern amenities in this beautifully restored home. Minutes away from San Diego's top attractions, including Balboa Park, Little Italy, and the vibrant Gaslamp Quarter. Two comfortable bedrooms provide a peaceful retreat. Fully equipped kitchen with new appliances. A perfect place to enjoy all that San Diego has to offer.

Kettner Row | Staycation-Featured Icon
Welcome to Kettner Row, a rare architectural masterpiece featured on Staycation Sports, an Emmy-winning show on the Destination Channel! Located in the heart of Little Italy—one of San Diego’s most desirable neighborhoods—and designed by renowned architect Jonathan Segal, FAIA. This detached row home is situated in the award-winning Little Italy Neighborhood Developers block (LIND). This modern home features dual master suites, a high-end designer kitchen, and luxurious spa bathrooms.

NEW Stylish❤️ of Downtown Little Italy w Parking/AC
Located in the heart of Little Italy San Diego, this street level condo has been completely remodeled and re-imagined to make your stay unforgettable. Designed with the eye toward comfort and entertainment. *AC w/ independent temp control in each room *Voice Controlled Sound System, 4K TVs in every room *Beautiful bathroom w/ dual showers *Walk to coffee, yoga & gyms, dining, entertainment, shopping! 6 min to Zoo 5 min Airport 9 min to SeaWorld 6 min Petco Park 8 min to Coronado

Spacious Studio In Little Italy with Parking!
Comes with a parking spots in a gated/covered parking garage within the complex. Centrally located in Little Italy. Close to great restaurants and coffee shops and a private balcony for an awesome view for plane watching. Bird Rock Coffee Roasters is located in the apartment complex on the first floor (Kettner Blvd). The Crack Shack and Ballast Point Brewery are right across the street. The Main Street of Little Italy is 2 blocks away and Waterfront Park is about 3 blocks.

Waterfront Little Italy Loft
Welcome to this modern one-bedroom loft in the heart of Little Italy, San Diego's most iconic neighborhood. With its central location, you'll be just steps away from all the best restaurants in the area - making it the perfect choice for couples & friends looking to experience the vibrant energy of the city. Here are a few things you will find; 80-inch OLED TV, full kitchen, California king bed, panoramic ocean views, an outdoor patio, & high speed internet.

Waterfront Loft | 1BR | Little Italy | Downtown
The local neighborhood is highly walk-able and perched along the San Diego Bay in Little Italy. Little Italy is the most vibrant neighborhood in downtown San Diego with a main street that abounds with restaurants, boutiques, craft beer, and wine bars all at your doorstep. This is a very urban location which brings a lot of urban noise. The unit sits adjacent the train and trolley line in the urban core. No parking provided, Ideal for guests without a car.
Popular amenities for Little Italy family-friendly rentals
Family-friendly home rentals with a hot tub

Hidden Spa w/ Sauna and Hot Tub near Balboa Park

Cozy University Heights Cottage

Mountain View Retreat in Gated Estate (Hot Tub)

1stResorts.com WATERVIEW FAMILY VILLA HOT TUB YARD

Jacuzzi, Firepit, Sauna & Ice Bath, Rest & Relax

Pool Oasis in Central Hillcrest by Park/Zoo

Beautiful Historic Home and Gardens Near Downtown!

5 Bed Oasis | Ocean View, Hot Tub, BBQ, Parking
Family- and pet-friendly home rentals

Beautiful Canyon Cottage located on a huge lot

Little Italy 2BR Loft Near Waterfront & Convention

Walk 2 Gaslamp & Petco; King bed, Parking/Patio!

Walk to Bars, Restaurants 1 BD Hillcrest, Parking

Little Italy 2BR Penthouse - Bay View + Garage

Downtown Dream 4

Sunny Good Vibes

Large Studio in Gaslamp, 3 bed w/ Parking included
Family-friendly home rentals with a pool

Modern Central SD Home w/ Pool & Spa Near Beach

Lux Villa: Heated Pool & Sauna

Paradise Lagoon Resort Style Pool Getaway

Resort Style Living with Pool, Spa, and Bay Views!

Your Modern Lux Pool Resort in the Heart of SD

Luxury Family Home Near Dining, Shops + Zoo

Lionhead - Private Boutique Home

Stunning 2BR/2BA| Plunge Pool, AC, Private
Destinations to explore
- Rentals with a sauna Little Italy
- Pet-friendly rentals Little Italy
- Rentals with a hot tub Little Italy
- Apartment rentals Little Italy
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- Waterfront rentals Little Italy
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- House rentals Little Italy
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- Rentals with pools Little Italy
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