
House holiday rentals in Mesa County
Find and book unique houses on Airbnb
Top-rated house rentals in Mesa County
Guests agree: These houses are highly rated for location, cleanliness and more.

Peach Pad! hot or cool tub 2 bedrooms 2 bathrooms
Sandstone views, outdoor area with private hot tub, can be kept cool in hot weather just message your preference. Bedrooms with en-suite bathrooms and are situated on opposite sides of the home for privacy. 7-10 minute bike ride to downtown, 5-10 minute walk to three vineyards,. Orchard surrounds 900 sq ft bedrooms and the living room have smart TVs, the kitchen is well equipped. The fenced yard has shaded outdoor areas to BBQ and enjoy sunsets. Best for 4 guests comfortable roll away bed for 5.
FamilyLocationCleanliness

420Friendly_HotTub_12kGameArcade_WineBar_5Bed
✨This is 420 Friendly home and you are welcome to smoke and use any marijuana products you would like in the comfort of the house. (no tobacco) I provide smoking accessories that are clean and sanitized after each guest and kept safe in a kitchen cabinet out of reach of kids. Dogs are welcome with a $50 fee. ⭐Multiple Wineries ➡15 min drive ⭐Mesa University ➡5 min drive ⭐Airport➡ 5 min drive ⭐Downtown GrandJunction ➡8 min drive ⭐Amtrak Train Station➡10 min drive ⭐Palisade Orchards ➡15 min d
LocationFamilyLaundry

The Wandering Nomad
Bring your heavy laden feet to rest in a wanderlust inspired home that will bring even the tamest nomad in you to surface. This 3 bed, 2 bath space is complete with everything needed for the modern day wayfarer. Spend the day on world-famous trails only to return to this suburban retreat, walking distance from the local fun and fare. Wifi is found throughout the home so you can stay connected to the world around you...or not. Life is all about choices and we hope you choose us as your home away.
ValueLocationLong stay

Blue Door Farm Vacation Rental
Beautiful, sunny, and brand-new vacation rental in the heart of southwestern Colorado's peach and wine country. Blue Door Farm Vacation Rental LLC offers full accommodations for 1 to 6 guests, with sweeping views of the Grand Valley from high desert to the Grand Mesa. A 15 minute drive to downtown Palisade and Grand Junction, and 5 minutes to 1 hour's drive to amazing year-round outdoor recreation, including hiking, biking, skiing, agritourism, festivals and wineries. Please note: NO pets.
FamilyValueKitchen

Modern Pali Farmhouse & Vineyard with hot tub
This spacious newer home with a hot tub is the perfect base for all your Palisade & Grand Valley adventures! Situated on 5 acres along the Fruit & Wine Byway, relax & take in the vineyard or mountain views from nearly every window! Go wine tasting, take a hike, go road or mountain biking, visit an orchard or lavender farm, paddle board on the Colorado river, ski at nearby Powderhorn, & more! Then after your day of adventuring enjoy the fireplace, outdoor living space, or a soak in the hot tub.
FamilyValueSleep quality

Powderhorn Grand Mesa Classy Family Cabin
Enjoy the outdoor recreation paradise of Powderhorn and the Grand Mesa from your spacious, cozy home. Winter brings downhill and cross-country skiing, snowshoeing, ice fishing and beautiful snowy vistas. Summer allows hiking and all things outdoors sounded by million acres of public lands. The 800 square mile top of the Grand Mesa hosts 300 lakes for fishing as well as paddle boarding and other small watercraft. Hiking trails galore and Powerhorn mountain supports summer mountain biking.
ValueLocationHeating

Dog friendly, 2 blocks to Main!Art on White Suite!
✨2 blocks to Main Street! Art on White Suite gives you an artistic, vintage, downtown experience with access to world-class mountain biking, winetasting, and much more! Our vintage home built in 1905, has quite a unique experience to offer. With love for our Community and Art, this eclectic space provides a relaxing, whimsical, light & airy stay. This 2 bedroom, one bath suite is attached to the main house- very private with a lovely back yard! We love this space and we hope you do too! 😊
LocationFamilyHospitality

The Pali House - 10 Acres & Wine Country Views
Welcome to The Pali House, a recently renovated 2-bed, 2-bath retreat on 10 private acres in Palisade wine country. Panoramic views, wrap-around porch, king bed, and the best stargazing in Colorado. Five minutes to wineries and dining, 40 minutes to Powderhorn. Designed for travelers seeking space, privacy, and stunning Western Slope sunsets. The home is extra large for groups of 4 and is fully stoked with everything you need to make Palisade home for a trip away. Your hosts, Joe & Trish
LocationValueCheckout

A Peach of a Farmhouse
Located on the Scenic Fruit and Wine Byway, our newly remodeled air-conditioned farmhouse is on a three-acre peach farm within easy biking distance to Palisade. Enjoy downtown Palisade's farmers market, distillery, and brewery. We're moments from many wineries and trailheads including Mt. Garfield & Palisade Rim. Begin, end or spend your day lounging on the front porch in the shade of mature peach trees or enjoying views of the rugged Palisades seeming to rise just outside the back door.
ValueFamilyWalkability

2 Bedroom Ranch House
Just a mile off of Highway 65 sits Tongue Creek Ranch. The Ranch is located in the fertile valley junction of Tongue Creek & Surface Creek. Enjoy your own private 2 bed 1 bath ranch house. Both bedrooms have a super comfy pillow top queen size bed. WIFI is a fast 1gig fiber optic line. Enjoy a full kitchen, washer and dryer, and a sofa in the family room. The front patio is always in the shade. Ask about the optional cabin on site for use as a private detached room for overflow family.
LocationValueParking

Fruita/Loma Guest House at the Perfect Day Getaway
This newly constructed "Green" home is a mix of modern and country styles and will surely inspire you to enjoy all of the outdoor activities the Grand Valley has to offer. The Perfect Day Getaway house is located on a quaint farm within 8 minutes of world-class hiking, mountain and road bicycling, and river rafting. It is a great launching point for day trips to Moab and the Grand Mesa as well! It was built to maximize the southern exposure and views of the Colorado National Monument.
FamilyValuePets

Galloway Ranch Palisade Colorado
Recent review: The best place we've ever stayed at, hands down! The location felt like a dead end road, yet close to everything. The yard had beautiful flower beds, not to mention the amazing view of Mt. Garfield! The house itself was very comfortable and had anything you can imagine in the kitchen, making a few at home dinners a breeze. Owners Note: One (1) dog 45 lbs max allowed unless an additional dog is approved in advance, please include # of people and # of dogs when booking.
FamilyValueCheck-in
Popular amenities for Mesa County house rentals
House rentals with a pool

Pool Hot Tub Mini Golf Game Room Sleeps 12
FamilyValueKitchen

Pool, hot tub, views and close to everything
LocationFamilyNearby

Palisade Peach Orchard Farmhouse w/Pool & Spa 18+
ValueFamilyAir conditioning

Corner Vista @ Palisade Legends
FamilyLocationHospitality

Lakeside Retro 4BR 2 BA, Pool, Hot Tub whole house
LocationFamilyBackyard

The Grant House
LocationValueNearby

Monument Resort
FamilyLocationAccuracy

Private Pool, Theater, Game Room, Family Ready
FamilyLocationCleanliness
Weekly house rentals

Reinvigorate on Main | Charming Fruita Retreat
FamilyValueCondition

Peach Chalet, views, quiet, 5 min to downtown
LocationFamilySkiing

Maple Downtown Fruita
ValueLocationWalkability

The Orchard House
FamilyValueLong stay

Family friendly, quiet & comfy 3BR home North area
ValueFamilyLaundry

Grand Junction Bike Hotel & Hot Tub
ValueLocationBathroom

GJ Relax on Rood - Hot tub - Location!
LocationValueAmenities

Downtown Palisade Charmer
LocationFamilyHeating
Private house rentals

Resort-like Adobe At Colorado Monument!
ValueFamilyBathroom

Kokopelli House • Modern Fruita Retreat + Garage
ValueLocationDecor

Highway 141 Retreat (WI-FI)
FamilyLocationHospitality

A cozy modern rustic cabin in Loma
LocationFamilyDecor

Walkable Downtown, Central A/C: The Sunshine House
FamilyValueLong stay

Romantic Wine Country. Farmstay at Posh Cottage
LocationFamilyIndoor spaces

Peaceful in-town oasis
FamilyValueSleep quality

Desert Gemini Ranch
FamilyLocationBackyard
Destinations to explore
- Hotel rooms Mesa County
- Tiny house rentals Mesa County
- Townhouse rentals Mesa County
- Condo rentals Mesa County
- Rentals with pools Mesa County
- Cabin rentals Mesa County
- Bed and breakfasts Mesa County
- Rentals with a hot tub Mesa County
- Apartment rentals Mesa County
- Farmstay rentals Mesa County
- Cottage rentals Mesa County
- Rentals with lake access Mesa County
- Rentals with a kayak Mesa County
- Family-friendly rentals Mesa County
- Pet-friendly rentals Mesa County
- RV rentals Mesa County
- Guesthouse rentals Mesa County
- Private suite rentals Mesa County
- House rentals Colorado
- House rentals United States





