
House holiday rentals in Mira Mesa, San Diego
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Top-rated house rentals in Mira Mesa, San Diego
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Popular amenities for Mira Mesa, San Diego house rentals
House rentals with a pool

3 BR Urban Oasis with Pool and Spa in Great Area
I am a San Diego local, but my family was coming to town and we needed more space. I picked this place because I knew my sister and brother-in-law would love being able to walk to all the restaurants and brewery nearby and my 6 year old nephew would get a lot of use out of the pool. The place exceeded my expectations, it was perfect for everyone. We spent a lot of time in the backyard swimming or playing board games, and my Mom got a lot of use out of the hot tub. Communication with the host was excellent and the place was comfortable and clean. The only downside is my family might visit too often now!

Southern California Luxury in Quiet Neighborhood
This is one of the most well thought out homes I’ve ever stayed at globally. The home is stunning and so well designed, even more beautiful than the photos. We loved how the pool was next to the master bedroom. This home has everything you need and more. Would love to stay agin!

La Jolla Beach House-Family Focused-3min to Beach
We had a fantastic week in La Jolla! John’s place was charming, spotless, and perfect for our family. The home was well-stocked with thoughtful amenities—including beach gear—and had everything we needed to feel comfortable. The location is unbeatable: a quiet, family-friendly neighborhood within a few minutes walking distance to the beach, great restaurants, coffee shops, and more. John was a friendly and responsive host who made everything easy from start to finish. Honestly could not have asked for a better host. Highly recommend for families looking for a relaxing, convenient stay in La Jolla. We’d love to come back!

Family Friendly Retreat:Game Room/Pool/Hot Tub/BBQ
Perfect place for our large group of adults. All amenities were available to us. Our hosts communicated well and promptly prior to and throughout our stay. I would highly recommend.

Kids Paradise San Diego - Funhouse
If you're currently looking for a place to stay in the San Diego area and have kids, stop looking. This is the place to stay! We thoroughly enjoyed our stay at Carrie's property. Kids Paradise was ideal for our young ones, and thanks to Carrie’s thoughtful preparations, we had everything we needed for a comfortable experience. This made it possible for our children to have a wonderful vacation, while also allowing us parents to relax. I highly recommend this accommodation for families with children of all ages. We look forward to the possibility of staying at one of her other properties in the future.

Luxurious North Park Home - Walk to Dining & Shops
We loved our stay at Mari Katherine’s Airbnb for a girl’s weekend in SD! It is a beautiful home that was spacious and thoughtfully designed and decorated to create a warm and welcoming atmosphere. The home feels private, but was in a fantastic location in North Park that was easily walkable to coffee shops, restaurants, etc. Mari Katherine sent clear instructions leading up to our stay, so the logistics of check in were clear and easy! When some logistical challenges came up during our stay, Mari Katherine was very responsive (even late in the evening) and offered solutions - we would be thrilled to visit again!

Bright and spacious home with views, pool & spa.
Nice place to stay in the San Diego area. Conveniently located within reasonable driving distance to popular attractions and nestled in a quiet, peaceful neighborhood. The backyard and pool are beautiful. The pool was by far the highlight of our stay. Miguel is an exceptional host: responsive, accommodating, and a pleasure to communicate with.

University Heights Oasis Getaway
Exactly as the other reviewers have described, it is just a beautiful oasis in a perfect quiet neighborhood. Don’t wait, book now!
Weekly house rentals

Home in San Diego
Stayed at this Mira Mesa home for a weekend with a group of 5 friends. It was very clean, spacious and had everything we needed. The location was great and was near many restaurants and stores. I recommend any group to stay here at this home!

Charming Family 3BR w/ Game Room
Wonderful place to stay—clean, home-y and cozy. I will definitely want to book here if I come back to San Diego! My family especially appreciated how toddler friendly this home was—my 1.5 yr old loved it here.

Close to Everything San Diego | Firepit + Office!
We visited San Diego with family for my brother in law’s graduation weekend and loved our stay! Home was exactly like the pictures, clean, and neighborhood felt safe. We definitely recommend this stay & will definitely be booking when we visit sunny SD again.

Urban Oasis - Just Remodeled
This was a great property I needed when a home repair took a few extra days. I was able to check in the same day of booking which was a huge blessing. The home was small but extremely well taken care of with all the amenities you could ask for. Thank you Wyatt I really enjoyed my stay !

Zen Loft Steps to the Beach
Ryder was a great host. I thoroughly enjoyed my stay there and felt right at home. I would recommend this to anyone looking to stay in Pacific Beach and explore a true highlight of San Diego!

The Seaford - sweeping ocean view and pet friendly
Lisa and Menotti have a beautiful beach escape that was perfect for our small group celebrating a birthday. The sliding door and balcony were beautiful and such a nice feature to let in the beach breeze. The house was pristine, comfortable, and so well designed. All amenities you would need. The hosts were super responsive and helpful and accommodated a late check out which allowed us to wake up early and check out low tide in the morning! Definitely will stay again.

Bright Cozy 3b/2b with nice backyard & BBQ
The place was so homey and very neat and clean. Very organized house. I will rent it again should I need a place to stay 😊

Cozy & Modern Family Home in Mira Mesa
The home was very affordable, comfortable and clean inside. The recent renovation was very tasteful and well done. The neighborhood was quiet and felt safe. Many of the homes in the neighborhood appear to be under some level of restoration. In our stay we had activities in La Jolla and Carlsbad so the location was good. Our experience in the home went well. We were 3 couples in our late sixties and early seventies. The 2 bathrooms were in great shape. There is a small back padio with some furnishings. The kitchen and dining area were quite nice as well!
Private house rentals

2 private masters, new beds & furniture, sleeps 12
Wonderful Stay for a Special Occasion We stayed at this Airbnb while visiting San Diego for our son's Marine Corps boot camp graduation, and it was the perfect home base for such a meaningful trip. The location was convenient— 30 minute drive to MCRD. The neighborhood was quiet and safe, which made it easy to relax and enjoy our time together as a family. The home was clean and comfortable. Communication with the host was seamless from start to finish. They were responsive, friendly, and provided helpful information about check-in process. We’re so grateful to have had a peaceful, comfortable place to stay during such a proud and emotional time for our family. We would absolutely recommend this place to anyone visiting San Diego.

Shadow House Mt. Helix
The most beautiful Airbnb! The location was amazing, it was very secluded. The hosts make you feel right at home.

Welcome to Casa Cortina!
Shahriyar was probably one of the best Host I’ve had, Very interactive and make sure everything was smooth and easy as possible. I would definitely recommend this location to anyone that’s in the San Diego area.

Renovated private ADU & spa, Mission Bay/ SeaWorld
My stay here was exactly how I wanted it to be. The home was very clean and had a lot of necessities like cookware, silverware, shower products, and so much more! Everything was super neat and organized. The bed was extremely comfy. The host was very easy to communicate with and made sure we had everything we needed, also made sure all our questions were answered. I am looking forward to staying here again when I return to San Diego. I would definitely recommend this to anyone who is thinking about staying here. You definitely get your moneys worth.

Charming Guest House in Old Town Poway
The house was private, quiet, new, and attractive, and everything was fully functional. It was perfectly situated in downtown Poway, but nevertheless quiet and private. The a/c units in the ceiling worked fabulously and quickly. Talissa was extremely responsive -- every request we made for replenishment of supplies was complied with within hours, if not minutes. I couldn't have asked for anything more, and I'll return next time I'm in town.

Peace in Penasquitos
Beautiful house, super clean, comfortable beds and couch, all amenities. Our family felt right at home. Everything is just like the pictures or better! There is a convenient 7-11 store just 3-5 min walking distance. Thank you!

Cozy quiet getaway, great mattress (1-br)
Loved this cute and cozy little place. Bed was very comfortable nice neighborhood and very pet friendly

Traveler's Dream New Modern Farmhouse Getaway
We truly enjoyed our stay! The home was immaculate, tastefully decorated, and had a warm, inviting atmosphere that made it feel like a true retreat. Every detail—from the cozy beds to the fully equipped kitchen—was clearly well thought out. The host was friendly, responsive, and made the entire process seamless. It was an exceptional experience, and we would happily return and recommend it to others!
Quick stats about house rentals in Mira Mesa, San Diego
Total rentals
210 properties
Total number of reviews
9.5K reviews
Family-friendly rentals
70 properties are a good fit for families
Pet-friendly rentals
30 properties allow pets
Rentals with a pool
20 properties have a pool
Rentals with dedicated workspaces
140 properties have a dedicated workspace
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- Rosarito Beach
- Oceanside City Beach
- Torrey Pines State Beach
- Tijuana Beach
- Pacific Beach
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- SeaWorld San Diego
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