
Holiday houses in Osborn Medical Center, Phoenix
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Top-rated holiday rentals in Osborn Medical Center, Phoenix
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Paradise Found, Conferences, Concerts, GCU, Pool
The historic Willo district of Central Phoenix is the perfect location to relax. Close to many attractions and major freeways, this completely renovated mid-century home offers the ultimate in both luxury and high-end fixtures. Inside, you can pamper yourself in the deep tub (with endless hot water) or multi-faucet shower, snuggle in the luxurious beds, or just laze in front of the 65" 4K TV. Outside, you can relax beside the pool (ask about heating), or just gather under the shaded patio.

Storybook Perfect Historic Cottage Near Downtown
Reliably operated by a top AZ Superhost with 4,500+ 5 star stays. Best of EVERYTHING - a perfectly preserved historic cottage, with all new mechanicals for reliable comfort, designed and staged by a local legend, on one of the prettiest streets in Del Norte Historic district. The only Phoenix district to be surrounded by greenery on three sides. All just mere minutes to Downtown Phoenix and the airport. The area is terrific - lots of local restaurants and bars, and of course the Arts District.

Rancho Bungalow + Casita with Airstream in Phx
5 minutes to the heart of Downtown! Designed for ultimate entertaining and a relaxing experience while staying in Phoenix! This unique property has a magazine-worthy bungalow with a renovated Airstream and Guest House. Living quarters open up to a private peaceful backyard with jacuzzi, fire pit, fountain, and outdoor seating. A style all its own! You will find yourself right next to stadiums and among the best coffee shops, local eateries, and entertainment the state has to offer. Lucky you!

Mid-Century Modern Charmer with FREE heated pool!
Newly updated Mid-Century modern residence in the heart of Central Phoenix. VERY private heated swimming pool surrounded by tall greenery. (Pool is heated at no charge) Pets stay for free! Super comfy luxury beds with variety of mattresses! Large open kitchen with full size stainless steel appliances and granite countertops. Located in a quiet historic neighborhood of Central Phoenix and close to fabulous dining, bars and services. Sought after location! 2 car garage! We support equality!

Private, Sparkling Clean Historic DTPHX Guesthouse
This charming studio guesthouse in the Campus Vista historic district is a fantastic find! Situated in a friendly neighborhood in the heart of Phoenix, this newly remodeled living space is cozy and practical, surpassing many of the similar properties in quality and character. A short ten-minute drive from the Sky Harbor Airport, and located within walking distance to two major bus lines and the light rail, the guests are sure to enjoy the easy access to all the popular downtown destinations.

Spanish Modernism 3BR with studio and pool
Modernism meets Spanish revival in this beautifully restored home plus rear studio in the Encanto Historic District. Meticulously restored - everything is brand new but with respect for the homes original character. Our home is located in a quiet, safe neighborhood while also close to hip restaurants, nightlife, and minutes to downtown. This home as been a very special second home for us and we welcome all - we will never decline a guest based on race, color, religion or sexual orientation.

Cute Casita Guesthouse (No Cleaning Fee)
Cute guesthouse w/kitchen, comfy queen bed, twin sofa bed couch, walk-in shower, nicely landscaped yard w/grill, fire pit & outdoor seating. Located in the heart of Central Phoenix. 15 min from PHX w/ easy access to major attractions (i.e., Camelback, Piestewa Peak, Desert Botanical Garden, Heard Museum). Centrally located near to the 10 Cactus League Spring Training MLB stadiums for 15 teams. Minutes from great restaurants and shopping. Non-smoking/no-vaping property/no pets.

2 Bedroom 2 Bath Home in Historic Neighborhood
This beautiful historic home is perfectly located for your stay in the Valley of the Sun. PHX Retreat is just minutes from Phoenix Sky Harbor Airport, downtown Phoenix, and Arcadia neighborhoods. PHX Retreat is also located in close proximity to multiple highways, so you will have a quick drive to Scottsdale, Tempe, Spring Training Venues, GCU, and any other destinations you are looking to explore. The quiet residential neighborhood is the perfect escape after a day of exploring.

Central PHX, Pet-friendly, 3 Bedroom, 2 Bath House
Pet friendly, Central Phoenix house. Remodeled, 3 comfy bedrooms, spa-like baths & a family room large enough to accommodate everyone. The private backyard provides a great space for BBQ's, family celebrations (on approval only) or just relaxing around the fire pit (while your pets run & stretch their legs). CENTRALLY LOCATED TO DOWNTOWN, GCU, LIGHT RAIL, HIKING, RESTAURANTS, THEATRES, SHOPPING & STADIUMS! Small gatherings ON APPROVAL ONLY! NO PARTIES! STR-2025-002573

Spacious Studio in Uptown Historic Neighborhood
Discover Uptown Phoenix and its vibrant charm! Nestled in the historic district, our property offers a serene escape in the heart of the Valley. This spacious, private studio features a resort-style outdoor retreat, a shared courtyard, a gourmet grill, two outdoor dining areas, and a cozy fire pit to unwind. Inside, relax in a comfortable living room, enjoy meals or card games at the dining table, and retreat to a glamorous bedroom for the perfect end to your day.

Guesthouse in city's most walkable neighborhood
Central location, easy access to I-10, I-17, 202, 51, and 9 minutes from Phoenix Sky Harbor Airport. Amenities abound in this updated private studio guesthouse in the upscale Encanto-Palmcroft Historic District of downtown Phoenix. Homes here have stunning architectural diversity. Recently ranked the wealthiest neighborhood in Phoenix, Phoenix Magazine named Encanto-Palmcroft 2009's "Best Places to Live" and the "Best Neighborhood to Walk Through" in 2015.

Adorable Willo Cottage in Historic Central Phoenix
Peaceful one bedroom cottage in unbeatable location within Central Phoenix. Walking/ biking distance from light rail, restaurants, Heard Museum and Phoenix Art Museum. Enclosed backyard with a shared washer/dryer on property. The cottage has a queen bed, mini kitchen and private patio. Property is cleaned and sanitized according to the Airbnb cleaning procedures. 15 minutes from Sky Harbor Airport. 5 minutes from Encanto Park (Golf Course)
Popular amenities for Osborn Medical Center, Phoenix holiday rentals
Other great holiday rentals in Osborn Medical Center, Phoenix

South Phoenix Gem

Modern 1-bedroom Apartment - 80 Walkscore!

Central Phoenix Cozy 2 Bedroom

Welcome to Luxe Stays

Your favorite PHX guesthouse!

Casa Gia- Quiet Luxury Biltmore Area | Heated Pool

Modern Chic Condo In Midtown w/ Pool & Hot Tub

Modern Midtown apt in quiet and vibrant community!
Destinations to explore
- Phoenix Convention Center
- Chase Field
- Lake Pleasant
- TPC Scottsdale - Champions Course
- Sloan Park
- Grayhawk Golf Club
- Tempe Beach Park
- The Westin Kierland Golf Club
- Peoria Sports Complex
- Salt River Fields at Talking Stick
- WestWorld of Scottsdale
- Desert Diamond Arena
- State Farm Stadium
- Arizona State University
- Camelback Ranch
- Grand Canyon University
- Salt River Tubing
- Surprise Stadium
- Goodyear Ballpark
- Scottsdale Stadium
- We-Ko-Pa Golf Club
- Papago Park
- Hurricane Harbor Phoenix
- Trilogy Golf Club at Power Ranch




