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Apartment holiday rentals in Panama Canal

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Panama Canal

Guests agree: These apartments are highly rated for location, cleanliness and more.

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Superhost
Apartment in Panama City
4.92 out of 5 average rating, 169 reviews

Apto 4 min from Tocumen Airport | 24-hr check-in

Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Guest favourite
Apartment in San Felipe
4.92 out of 5 average rating, 63 reviews

Estilo colonial con calicanto y balcón privado

Bienvenidos a un apartamento acogedor donde el encanto de las paredes de calicanto se mezcla con detalles cálidos y un balcón perfecto para disfrutar del ambiente y la vista del Casco Antiguo. Tenemos una ubicación privilegiada en una de las principales avenidas del Casco, desde aquí podrás acceder fácilmente a sitios históricos, restaurantes, cafés, bares y rincones llenos de encanto. La idea es que llegues, te sientas cómodo, disfrutes la ciudad a tu ritmo, ya sea solo, en pareja o en familia.

Guest favourite
Apartment in San Felipe
4.96 out of 5 average rating, 259 reviews

En el corazón de Casco, remodelado y con parking

Escápate y descubre casco antiguo en este remodelado , cómodo y céntrico alojamiento en el corazón de Casco Viejo. Nuestra ubicación es lo mejor, te hará regresar. Cerca de restaurantes, Bares, Impresionantes Iglesias y Museos. La propiedad data del siglo XVII (1756) historia y buen ambiente. Podrás explorar la zona a pie, cocina full equipada, cama king europea, te sentirás como en casa, rodeado de las famosas paredes de calicanto. -Amplia sala de estar -Cocina full equipada

Top Guest favourite
Apartment in San Felipe
4.98 out of 5 average rating, 128 reviews

The View of Casco: Designer Loft with best Balcony

Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! ​Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. ​You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife

Superhost
Apartment in San Felipe
4.77 out of 5 average rating, 198 reviews

Apartamento tipo estudio en el corazón de Casco

¡Bienvenidos a Casa Pérez, tu refugio en el corazón del Casco Viejo! Disfruta de una ubicación privilegiada y de las mejores vistas desde un espectacular balcón privado frente a la plaza más emblemática del Casco. Ideal para 3 personas, este acogedor y luminoso apartamento de un dormitorio incluye Wifi, aire acondicionado, sala, comedor, cocina equipada, lavadora y elevador para tu comodidad. Disfruta de una estadía inolvidable en un ambiente cálido y completamente equipado.

Top Guest favourite
Apartment in San Felipe
4.97 out of 5 average rating, 38 reviews

Walk to Everything | Luxury Stay in Casco Viej

Wake up overlooking one of the last historic bastions of Casco Viejo, sip your morning cofee on a private balcony, and step directly into Panama City most vibrant and wakable neighboorhood. Surrounded by colonial architecture, charming plazas, and a vibrant culinary scene, this space invites you to experience Panama with style and tranquility. Ideal for those seeking an exclusive, walkable, and characterful environment in one of the city's most iconic areas.

Guest favourite
A spacious living area is highlighted by a large sectional sofa and a low wooden shelf displaying modern decor. Glass doors open to a balcony showcasing outdoor seating, with natural light illuminating the room. The tile floor adds a warm touch to the ambiance.
Apartment in San Felipe
4.82 out of 5 average rating, 137 reviews

Stunning Terrace Among Ruins in Casco Viejo

Welcome to your Casco Viejo retreat! This spacious apartment, perfect for up to 8 guests, offers a unique blend of modern comfort and historic charm in Panama City’s most iconic neighborhood. Located in the heart of Casco Viejo. The highlight of this beautiful space is the stunning terrace nestled among historic ruins, where you can relax, enjoy a meal, or simply take in the timeless atmosphere. This is more than a stay – it’s an unforgettable experience.

Guest favourite
A cozy sitting area is highlighted by a large window offering views of the vibrant plaza and cathedral. Two comfortable armchairs are positioned beside a small coffee table on a textured rug. Natural light fills the space, enhancing the warm tones of the wooden floor.
Apartment in San Felipe
4.91 out of 5 average rating, 126 reviews

La mejor vista del Casco Antiguo

¡Bienvenidos a este encantador alojamiento situado en el corazón del Casco Viejo, ubicado en el tercer piso frente a una de las plazas más emblemáticas de Panamá, la Plaza Catedral! Gracias a su privilegiada ubicación, disfrutarás de una vista única a la plaza y a la imponente Iglesia Catedral. Justo en esta animada plaza, tendrás a tu disposición una amplia variedad de restaurantes y tiendas donde podrás adquirir recuerdos de este maravilloso viaje.

Guest favourite
Apartment in San Felipe
5.0 out of 5 average rating, 37 reviews

Private parking & rooftop | Studio Casco Center

This beautiful restored studio from the 1870s blends history with modern design. Enjoy a private rooftop terrace with seating and BBQ, plus private PARKING—ideal after exploring Casco's best restaurants, galleries, and nightlife steps away. ✨ Highlights: - Historic Charm: Original tile floors and exposed colonial stone walls. - Comfort: King bed, living room, and full kitchen. - Amenities: Private rooftop & private PARKING. - Great location

Guest favourite
Apartment in Panama City
4.89 out of 5 average rating, 102 reviews

Moderno, céntrico y cómodo (104)

Moderno y acogedor estudio en el corazón de Panamá. Perfecto para explorar el Casco Antiguo, la Cinta Costera y más. Cocina completa, cama queen, sofá cama doble, aire acondicionado, WiFi rápido y baño privado. Ideal para 1–4 personas. Acceso privado, ascensor y check-in autónomo. Rodeado de restaurantes, transporte y sitios turísticos. ¡Tu base ideal para conocer la ciudad! 🧳 Estancias largas bienvenidas (descuentos aplicables)

Guest favourite
Apartment in San Francisco
4.98 out of 5 average rating, 162 reviews

Apartamento completo en Panama

Este encantador apartamento está ubicado en uno de los mejores barrios de Panamá, San Francisco, un lugar céntrico donde encontrarás amplía gastronomía, lugares de diversión, cerca a estaciones de buses, y al centro comercial más importante de la ciudad, Multiplaza. Este apartamento céntrico y tranquilo es una oportunidad que no querrás dejar pasar. Ofrece la combinación perfecta de comodidad, belleza y ubicación conveniente.

Top Guest favourite
Apartment in San Felipe
5.0 out of 5 average rating, 33 reviews

Most Beautiful Loft in the Heart of Casco Viejo

Discover Casco Viejo from this beautiful loft, perfectly located. Casco Viejo, UNESCO World Heritage Site, known for its colonial buildings, and iconic streets. This vibrant neighborhood offers many restaurants, coffee places, museums, and an exciting night life. Just steps from Fonda Lo Que Hay, ranked among Latin America's Top 50 culinary destinations. Close to MYKA Greek Yogurt and the iconic La Compañía Hotel.

Popular amenities for Panama Canal apartment rentals