
Apartment holiday rentals in Panama
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Top-rated apartment rentals in Panama
Guests agree: These apartments are highly rated for location, cleanliness and more.

In the heart of Casco, refurbished and with parking
Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen
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Best Location – Fancy Apartment in Casco Viejo
Experience absolute luxury in our fully remodeled loft, with access to a spectacular 360° rooftop terrace, where you'll enjoy breathtaking views of the city and skyline. The building also features an elevator for your convenience. Located right in front of a vibrant plaza with renowned restaurants, the location is truly unbeatable, and security in the area is excellent. Relax in the rooftop, enjoy sunset views from the terrace, and experience the unique charm of Panama’s historic Casco Antiguo
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Apto 4 min from Tocumen Airport | 24-hr check-in
Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!
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Casa Melina Torio Cozy upscale 2b jungle apartment
Stylish jungle two bedroom apartment Walking distance 5 restaurants. attractions: waterfall, jungle trails, River, Beach & Morrillo Surf break. Fully equipped with everything you need & want (Drinking water filter, Hot water, AC, Starlink WiFi & TV). Perfect for a couple/family seeking to blend work and play. Designed so our guests can fully experience our Torio culture. Cook with local fresh ingredients, discover Torio on foot & return to rest in the coziest rental you have ever experienced.
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Luxury Mid-Century Apartment In Casco Viejo
Luxury mid-century one bedroom Boutiqe 72 m2 apartment. Step into the elegant, functional and comfortable place that we offer with love. The apartment located within a beautiful two-floors antique building in the heart of Casco Viejo. The apartment includes a well equipped brand new kitchen, a dining area and a spacious living room, also a balcony with a view of the lively streets below. The tranquil bedroom has an ensuite bathroom and a walking closet that fitting perfectly to your needs.
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Pebos Reef Apt 1 · Beachfront · Sea View Terrace
This spectacular beachfront property is ideally situated with an incredible view of neighboring islands, fishing friendly waters, and mesmerizing snorkeling spots for children and adults to enjoy. Monkey greetings from the jungle adjacent, octopus and colorful native fish inhabited waters, and lazy bear sloth sightings are all part of your daily experiences here at Pebos Reef! If you are lucky you will even see dolphins from the terrace ! A terrace on the sea is all you need.
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The View of Casco: Designer Loft with best Balcony
Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife
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Gorgeous Flat in the best location in Casco Viejo
This cute and stylish studio is perfectly located in the heart of Casco Viejo, Panama City’s most charming historic district. Recently renovated, it combines modern comfort with classic charm inside a beautiful colonial building—just steps from top restaurants, bars, monuments, and attractions. The space includes a comfortable sofa bed, making it ideal for a couple or a small family looking to enjoy the vibrant atmosphere of Casco right outside their door.
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The best view of the Old Town
Welcome to this charming accommodation located in the heart of Casco Viejo, on the third floor facing one of the most iconic squares in Panama, Plaza Catedral! Thanks to its privileged location, you will enjoy a unique view of the square and the imposing Cathedral Church. Right in this lively square, you will have at your disposal a wide variety of restaurants and shops where you can buy souvenirs of this wonderful trip.
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Most Beautiful Loft in the Heart of Casco Viejo
Discover Casco Viejo from this beautiful loft, perfectly located. Casco Viejo, UNESCO World Heritage Site, known for its colonial buildings, and iconic streets. This vibrant neighborhood offers many restaurants, coffee places, museums, and an exciting night life. Just steps from Fonda Lo Que Hay, ranked among Latin America's Top 50 culinary destinations. Close to MYKA Greek Yogurt and the iconic La Compañía Hotel.
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Full apartment in Panama
This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.
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Modern, central and comfortable (104)
Modern and cozy studio in the heart of Panama. Perfect for exploring the Old Town, the Coastal Belt and more. Full kitchen, queen bed, double sofa bed, air conditioning, fast WiFi and private bathroom. Ideal for 1–4 people. Private access, elevator and self check-in. Surrounded by restaurants, transportation, and tourist sites. Your ideal base to explore the city! 🧳 Long stays welcome (discounts apply)
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Popular amenities for Panama apartment rentals
Weekly apartment rentals

Private parking & rooftop | Studio Casco Center
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Colonial style with calicanto and private balcony
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Walk to Everything | Luxury Stay in Casco Viej
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Peaceful Stay in the Heart of Casco
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A warm and cozy flat in Casco Viejo
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Amazing experience in Casco Viejo historical site3
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Panoramic Ocean View | The Sands
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Luxury Apartment | Walk to Restaurants & Shops
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Private apartment rentals

Casa Esmeralda Refined 120 m² Duplex in Casco Viejo
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Escape to the Pacific of Panama
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Casa de Mono | Tropical Garden Retreat, Near Ocean
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Panama City Ocean View
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Seaview Studio
BeachDecorLong stay

Stunning loft in Buenaventura Golf&Beach Resort
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Tropicool Casco Loft w/King Bed & Rooftop
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3-bedroom apartment with exceptional waterfront views
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Apartment rentals with a hot tub

Ocean View Apt in Panama, Yoo&Arts
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New Flat with Ocean + City Views
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Spacious 4Br Beachside Getaway at Playa Escondida
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Beachfront Paradise in a 5-Star Resort
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Ocean View Apartment - Playa Escondida Resort
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Marina House at Playa Escondida Resort
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Tropical Paradise at Playa Bonita
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Apartment #4 Greenscape Suite
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