
House holiday rentals in Panama
Find and book unique houses on Airbnb
Top-rated house rentals in Panama
Guests agree: These houses are highly rated for location, cleanliness and more.

Puntita Manzanillo, fantastic sea and jungle
Come visit one of the most unique and exclusive properties in the Panamanian Caribbean. A magical completely private 5 acre property nestled between the Caribbean Sea (500meters of ocean front) and the jungle. Surrounded by a garden of corals and visited by monkeys and macaws. Our energy is solar and we have our own aqueduct. Temperature oscillates between 72 and 84 degrees F. It is rented in its entirety. It has 3 one bedroom cabins with full baths. Satellite Internet (Starlink) is provided.
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Beach House-Amazing Pool & Jacuzzi - Pet Friendly
Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with Smart Home Energy Management Systems.
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Spacious, Over the Water Home with Plunge Pool
Perched over the water in Bastimentos Bay, this well-appointed four bedroom and three bath single family home combines classic Caribbean architecture with modern sensabilities. With over 2,000 sq ft of comfortably furnished spaces, there’s room enough for eight adults to spend time together - or apart - in any weather. BBQ poolside, stargaze from the hammocks, fish off the dock, walk to restaurants, or flag down a water taxi from your private boat dock for the ten minute trip to Bocastown.
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Vista Pacífica | Jacuzzi, Piscina, Vistas y Alexa
Somos una casa de campo para máximo 10 personas en un terreno cercado de 1,000 m² en lo más alto de Valle Los Lirios, Las Uvas de San Carlos, manteniendo una sensación de aislamiento. Ubicada en un vecindario con videovigilancia 24/7 y garita de seguridad. Ofrece vistas al mar, Valle de Antón y bosques. Relájate en el jacuzzi con hidromasaje y jets o nada en la piscina. Contamos con hamacas, barbacoa, mesa de ping pong, fogata y asistente de voz Alexa. Hay estacionamiento para máximo 6 autos.
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Casa Coco - Beautiful Mountain Villa With AC
Elegant and modern, our home strikes the perfect balance between luxury and warmth. With ample space to accommodate large groups and families, as well as cozy and inviting for smaller groups. The yard features a covered social area, ideal for relaxing or entertaining. A lush garden adorned with vibrant greenery includes a charming mango tree and mountain peak views. A 5 minute walk to restaurants and the open air market. If you have a group larger than 12- please reach out to us directly.
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Spacious House | Garden and Terrace | Pet Friendly
Discover the pleasure of staying in a private, elegant, and light-filled villa within the exclusive Playa Blanca Beach & Lagoon. Start your day with the tropical breeze on the terrace, relax by the pool, and enjoy a short 10-minute walk to the beach. Perfect for families and travelers seeking rest, security, and resort-style comfort. Ideally located 10 minutes from Scarlett Martínez Airport and 2 hours from Panama City, it's the perfect place for an unforgettable getaway by the sea.
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OceanView-Rooftop Jacuzzi&Pool | Concierge Service
Unique 3-story beach house – one of a kind. 7 bedrooms, 13 beds, 8.5 baths. hot water. Every room with full bath -AC’s and ceiling fans in all rooms, separate laundry -Rooftop area pool, Jacuzzi, bar, BBQ(charcoal & gas) with amazing ocean view -High ceilings, large open kitchen and living area. -Spacious balcony for dining or relaxing. - 5 min. walk to the beach. -Parking for up to 7 cars - Base rate covers up to 4 guests, with a $40 charge per additional person, per night.
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El Palmar, playa a 50 metros
Escucha las olas desde la privacidad de nuestra terraza y crea recuerdos inolvidables en este alojamiento único y familiar a pocos paso de la playa con piscina privada. El palmar es una comunidad tranquila con varios restaurantes disponibles a unos pasos de la casa. La propiedad esta totalmente cercada para la tranquilidad y seguridad de hijos y sus mascotas adicional tienes wifi, TV cable en ambas habitaciones y aires acondicionados en la sala comedor y en todas las recamaras
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Modern House with Great Views and Heated Pool
Modern mountain house in Altos del Maria, Panama, a gated comunity at just 1 hour and 30 minutes away from Panama city. The comunity has rivers, bird watching trails, and is only 25 minutes away from the pacific beaches. Its a perfect place to take a break and relax. The house has a modern decor, infinity pool, 2 bedrooms with A/C, wifi, dishwashing machine, washer and dryer and great view of the mountains. Free late checkout is given for rentals checking out on Sundays.
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Casa Rosie - Dream Home on Tabogá Island
Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.
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Villa Acuario
Relaxation is guaranteed in this one-of-a-kind glass house nestled in the lush mountains of Altos del María. Surrounded by nature and designed with floor-to-ceiling glass walls on all sides— as if you’re living inside a crystal ball. With no direct neighbors, panoramic forest views, it is perfect for a family getaway, a quiet reset, or an extended stay. The home offers light-filled interiors during the day and unforgettable stargazing nights from the rooftop.
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Tropical Haven with Pickleball/Yoga Platform
Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.
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Popular amenities for Panama house rentals
House rentals with a pool

Coronado Coastal Villa • Walk to the Beach
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Casa de Playa AX8 cerca de la ciudad!
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Casa Namuiki by the Mountains
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Playa Malibu Beach House.
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Casa De Ola, Jungle Beach Cabin
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Spectacular ocean view, private beach access, pool
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Paradishaus in Natur in Playa Coronado mit Pool
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Casa Samambaia - sea view tropical paradise w pool
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Weekly house rentals

Casa Pelicano - Tropical house w pool and seaview
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Seaside Sanctuary • Steps to Surf • Fast Internet
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Bocas Sunset Beach House
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Beach side stay at Casa Blanca
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Beachfront · Large Sea View · Family Friendly
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Spectacular Beachfront House
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Cómodo y lujoso apartamento
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Amplia Residencia Privada en Excelente Zona
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Private house rentals

Luxury Beachfront Home • Private Pool • Coronado
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CASA STARE | Frente al mar: Playa, Jacuzzi y Surf
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Casa para grupos · 6 hab/6 baños cerca del Canal
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Casa Palenque Panamá
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Discounted Beachfront | Luxury & Style | King Beds
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Private Beachfront Getaway
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BeachfrontHouse+Kitchen+Balcony+AC+WiFi@IslaGrande
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Beachfront Home | En-Suites + Chef & Tours Avail
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Destinations to explore
- Beach condo rentals Panama
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