
Guesthouse holiday rentals near Saguaro National Park
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Top-rated guesthouse rentals near Saguaro National Park
Guests agree: these stays are highly rated for location, cleanliness and more.

The Zendo Oasis. Your Private Resort in Tucson.
Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in a hot stone sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies. Lounge by the pool in the sun or shade on the deck or under louvered patios. The Zendo is close to the UA and downtown. Book now and escape the ordinary!
4.96 out of 5 average rating, 524 reviews
Knightly's Ranch Guesthouse
A beautiful, secure, private home on a fenced & gated private 5 acre property that sits adjacent to Saguaro National Park with horse & hiking paths galore. Access to trails, golfing, fishing, birding, photography, local biking and horseback riding. Desert landscape with abundant Tucson wildlife, it's secluded but easy access to anywhere in Tucson. Western setting & user-friendly site. A ranch on a dirt road with horses, dogs & chickens, bbq, stargazing & sunsets. The mountains & moon are yours!
4.85 out of 5 average rating, 278 reviews
RetroTrek Bungalow Private-Fenced-Cozy
Our bungalow is nicely suited for 2, features a separate kitchen, a 3/4 bath, & large main room for sleeping or relaxing. We offer a private entrance with carport parking. Yard is fenced, with dog door, up to 2pets are welcome. Centrally located, within minutes of the airport, downtown and the University of Arizona. We are within walking distance to Reid Park for golfing or a visit to the Zoo. Even though we are midtown with easy access to many areas of town, you will find it surprisingly quiet.
4.98 out of 5 average rating, 340 reviews
Little Hummingbird House -An Enchanted Food Forest
Casita Colibrí (Little Hummingbird House) - lush oasis flourishing with life nestled in The Enchanted Food Forest-home to fruit trees, gardens, koi pond, chickens, giant tortoise, dogs, cats, and its namesake, hummingbirds in Tucson's heart. Enjoy fresh eggs & fruit, wander garden paths, relax poolside, or watch koi beneath the waterfall. It's not just a place to stay—it’s a special place to slow down, reconnect, and breathe in beauty and life, where peace & magic are woven into every corner.
4.96 out of 5 average rating, 457 reviews
West-side Trailhead Retreat in the Sonoran Desert
2017 guest house in Tucson Mountain foothills adjacent to Sweetwater Preserve (14+ mi.s of trails: mountain biking, horseback, running, & hiking)! Enjoy the giant soaking tub, BBQ grill, sunsets & patio. A full kitchen, sitting area, bath & BR are downstairs (550 sq. ft.). Up a 90-degree ladder to BR/retreat space, wonderful for getaway views. Our property is a 3-acre lot w/ desert flora/fauna, stars, & quietness, yet only 10 mi. from UA. Horses add to the ambiance with a taste of ranch life.
4.99 out of 5 average rating, 371 reviews
Tranquil Bears Path Casita
This Property is truly a unique oasis in the desert! It is one of the few urban areas in Tucson that offers you the best of both worlds! A place to come home to and enjoy the quiet nights, plentiful stars, and walks among the the numerous Saguaros, Mesquite and Desert Pine trees. All while being right in the heart of Tucson's East side just minutes from shopping and restaurants! Our extraordinary place is close to Mt Lemon, Sabino Canyon, hiking, running, biking trails and riding stables.
4.98 out of 5 average rating, 375 reviews
Attractive Casita In Tucson
A charming getaway casita with stunning views of the majestic Saguaro National Park and the Picture Rock Mountains for spectacular sunsets. The 5-acre site is home to many varieties of cacti, including giant saguaros and other native plants and trees. Through the casita's panoramic windows, you can observe desert vegetation, birds, rabbits, coyotes, bobcats, javelinas, and deer. An evening bath in the jacuzzi under the starry sky will certainly remain in your memory for a long time.
5.0 out of 5 average rating, 128 reviews
The Southwest Knest
Cozy and charming, this private guest house sits in the heart of Tucson and makes a perfect home base during your visit to the Southwest! Studio layout is spacious and relaxing for 2. Fully equipped kitchen, bathroom with walk-in shower, Ghostbed mattress, and comfortable work space/fast wifi for those of you working remotely. Easy access to airport, U of A, Saguaro NP, shopping, and hiking trails. Coded entry makes it a breeze to come and go, no shared keys. Come rest at the Knest!
4.97 out of 5 average rating, 532 reviews
Central and Stylish Midcentury Pool House
Our beautiful adobe pool house is a Tucson gem. Comfortable queen bed, fireplace, and stylish modern furnishings with large windows looking out to trees and sparkling pool. Vaulted ceilings and natural light make for a restful space. Located in historic Jefferson Park, it’s a midtown oasis close to the UofA and two blocks from the UMC/Banner Medical Center. Midtown/University location allows for convenient access to all of Tucson. *Newly improved high speed WiFi 11/1/2021
4.95 out of 5 average rating, 570 reviews
Tucson Poet's Studio
Tucson Poet's Studio was featured in Architectural Digest (10-1-2025) “50 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).
4.96 out of 5 average rating, 924 reviews
Charming Desert Guesthouse
Welcome to the desert! You’ll enjoy views, views, and more views of a beautiful desert landscape. We are centrally located on the east side of Tucson, placing us 10-20 min from great restaurants, hiking trails, Saguaro National Park and the University of Arizona. Our charming guesthouse has everything you’ll need and is pet friendly. You’ll have a private getaway with parking on site and a spacious outdoor shower. We can’t wait to host you.
4.92 out of 5 average rating, 170 reviews
Time Capsule in the Sonoran Desert
Vibrant space-age cabin on an 11-acre desert art sanctuary near Saguaro National Park, 35 mins from Tucson! Features WiFi, AC/heat, outdoor bathroom deck & eco-amenities. Sits 15 yards from Groovy Glamper. 🚫 NO PETS/ESAs (Service Animals welcome). Delicate art decor makes this space strictly UNSUITABLE for children/minors. ⚠️ IMPORTANT: Before booking, note that check-in is strictly in person and no later than 10:00 PM. No exceptions!
4.99 out of 5 average rating, 442 reviewsPopular amenities for guesthouse rentals near Saguaro National Park
Family-Friendly guesthouses

Casa de Amapola. Desert retreat, 15 mins to city.
4.98 out of 5 average rating, 194 reviews
Private Tucson Desert Guest House Getaway
4.97 out of 5 average rating, 893 reviews
Charming Private Oasis Casita with Pool & Hot Tub
5.0 out of 5 average rating, 221 reviews
Peaceful Desert Setting
4.98 out of 5 average rating, 131 reviews
Sam Hughes oasis with pool, close to U of A
4.92 out of 5 average rating, 245 reviews
Cozy midtown guesthouse
4.99 out of 5 average rating, 153 reviews
Rooftop Casita in Civano Private Patio & Mtn Views
5.0 out of 5 average rating, 175 reviews
La Bougainvillea, Separate, Walled & Gated
4.86 out of 5 average rating, 778 reviewsGuesthouses with a patio

Adobe Carriage House downtown Chiminea+Ramada
4.94 out of 5 average rating, 182 reviews
Midtown-New Constr/Hot Tub/Full Kitchen/Private
4.96 out of 5 average rating, 120 reviews
The Coop- Luxury guest house with ideal location
4.96 out of 5 average rating, 255 reviews
Midtown House near TMC & UofA•Fast WiFi •Self ChIn
4.84 out of 5 average rating, 160 reviews
Sunshine Loft
4.9 out of 5 average rating, 256 reviews
Historic University area Downtown 4th Ave Studio!
4.77 out of 5 average rating, 252 reviews
Dunbar Springs Desert Oasis Guesthouse
4.89 out of 5 average rating, 295 reviews
Casita Chapulin
4.98 out of 5 average rating, 155 reviewsGuest house rentals with a washing machine and dryer

The Outpost
5.0 out of 5 average rating, 210 reviews
Modern 1 bdrm Casita in Central Broadmoor Village
5.0 out of 5 average rating, 113 reviews
Fun Retro Cottage
4.98 out of 5 average rating, 165 reviews
Luxy House
4.9 out of 5 average rating, 227 reviews
Desert Getaway 2 Bedroom Guest House
4.97 out of 5 average rating, 153 reviews
Golden moments in Oro Valley/Tucson
4.98 out of 5 average rating, 447 reviews
Extra-Spacious 1BR Guesthouse Close to UA
5.0 out of 5 average rating, 190 reviews
🌵 Central Desert Oasis 3 🌵
4.93 out of 5 average rating, 273 reviewsOther guest house holiday rentals

Hues Casita - Airy Studio Near U of A
4.96 out of 5 average rating, 135 reviews
The Dog House
4.83 out of 5 average rating, 237 reviews
Spanish Bungalow Casita with Private Patio
4.92 out of 5 average rating, 541 reviews
Casa Rosa (Desert Oasis Casita w/ Mt Lemmon Views)
4.91 out of 5 average rating, 418 reviews
Guesthouse Studio in Barrio San Antonio
4.92 out of 5 average rating, 116 reviews
Peaceful Casita in the Foothills
4.96 out of 5 average rating, 776 reviews
Private Casita in Casas Adobes
4.92 out of 5 average rating, 235 reviews
Reflection House
4.86 out of 5 average rating, 242 reviewsDestinations to explore
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- Mount Lemmon
- Mt Lemmon Ski Valley
- University of Arizona
- University of Arizona
- Sabino Canyon
- Tucson Convention Center
- Arizona-Sonora Desert Museum
- Tumamoc Hill
- Patagonia Lake State Park
- Kartchner Caverns State Park
- Sabino Canyon Recreation Area
- Biosphere 2
- Titan Missile Museum
- Tucson Botanical Gardens
- Catalina State Park
- Reid Park Zoo
- Tucson Museum of Art
- Rialto Theatre
- Pima Air & Space Museum
- Mission San Xavier del Bac
- Tumacacori National Historical Park
- Children's Museum Tucson
- Trail Dust Town
- Sonoita Vineyards





