
Holiday houses in Santa Panagia
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Top-rated holiday rentals in Santa Panagia
Guests agree: these stays are highly rated for location, cleanliness and more.

Penthouse Lady Packard
Lady Packard’s Penthouse just had a glow up!✨ A stunningly elegant, spacious and comfortable house with four levels, all above ground because of the sloping, pedestrian street on which it is built. Free parking is just steps away. The location is ideal, peaceful with amazing views, and just a few minutes’ walk from the city's center. The house sleeps 6 adults in 3 separate bedrooms. Perfect for a family holiday or a friends getaway, the common spaces comfortably accommodate everyone at once.

One step to Ortigia! Bicycles & Balcony
Bright and stylish renovated flat just steps from the city center and Ortigia—you can walk to all the must-see spots with ease. Cozy and welcoming, it’s the perfect home base for your holiday in Sicily! ☀️ Sunny balcony for relaxing moments en plein air 🚲 FREE bicycles available throughout your entire stay 🚗 Hassle-free street parking – and it’s free 24/7! We also have two more apartments in the same building—check out my profile to discover them and read our glowing 5-star reviews!

Casa Sirokos
Casa Sirokos è una villetta indipendente fronte piscina, immersa nel verde del quartiere residenziale più panoramico di Siracusa, caratterizzata da un'architettura locale che si fonde con ampi spazi esterni e giardini tipici della campagna siciliana. La villetta è uno dei due alloggi indipendenti che fanno parte di questa struttura, che propone anche un appartamento situato al primo piano di un'antica villa padronale. L'atmosfera sofisticata e rilassante ci contraddistingue!

Light and Relaxation: Large Open-Plan Space Overlooking the Garden
Situato in un’ala riservata della villa con ingresso indipendente, questo open space di 95 mq unisce raffinatezza e modernità. Le ampie vetrate inondano di luce naturale gli ambienti, mentre l’arredamento definisce con naturalezza le diverse aree. Un perfetto equilibrio tra design, comfort e natura: gli spazi si fondono armoniosamente con il giardino, creando relax e privacy. Per motivi di sicurezza e comfort la struttura ospita bambini solo dai 10 anni compiuti in su.

Agàpe Ortigia
Agàpe Ortigia is an accommodation created with Love in the magical island of Ortigia, in the historic center, a stone's throw from the Duomo and the major sites of interest. The independent room is large and spacious, has a double bed, TV, free Wi-Fi, tea and coffee corner, but the peculiarity of this accommodation apart from the furnishings is the bathroom which, in addition to having the main amenities, offers a large sunken tub where you can relax.

Casa Salgiò
Cozy and modern apartment on the outskirts of Syracuse, just a 10-minute drive from the historic center and in a well-served area. The apartment, completely renovated, consists of a living area with a double sofa bed, an equipped kitchenette, a bedroom, a small room with a bed, a bathroom with a shower, a storage room and a laundry area. The living room and bedroom overlook a veranda from which you can see glimpses of the sea and Mount Etna.

Casa Sbarcadero
Casa Sbarcadero is just a 6-minute walk from the historic center of the island of Ortigia and about 20 minutes from the Neapolis archaeological area. The apartment offers access to the public solarium below, perfect for relaxing. The apartment consists of three bright rooms overlooking the small port, two bathrooms, a spacious living room and a well-equipped kitchen. The bus and train station is a 15-minute walk away.

Regine luxury apartment by Dimore in Sicily
CIN:IT089017C25PMCIRC7 CIR:19089017C221260 Welcome to Regine Luxury Apartment, an exclusive retreat in the heart of Ortigia, Syracuse. This elegant 4-bedroom, 5-bathroom apartment, located in a historic building, offers spectacular sea views from its private terrace. Enjoy the fully equipped kitchen and proximity to local attractions. Ideal for families and groups, it offers an unforgettable Sicilian experience.

Sky Rooftop Ortigia
In the vibrant heart of Ortigia, just a few steps from the touristic port, this charming home welcomes you in a truly unbeatable location. Here, you can immerse yourself in the authentic atmosphere of the historic center, surrounded by picturesque alleys, local shops, and traditional restaurants, with the sea always within sight. The apartment is located on the third floor and is accessible by stairs only.

Comfortable apartment with reserved parking space
Apartment in an area well served by shops, supermarkets, bars, pizzerias, tobacconists, newsagents, bakery, bank and a characteristic street market with fish, fruit and typical products. Well equipped kitchen. Easily accessible by car and equipped with a reserved parking space inside a fenced condominium courtyard. The apartment is equipped with books and various touristic documentation on Sicily.

Casa Francesca
Detached house directly located on the rocks in a private condominium context in the protected marine area of Plemmirio, in the seaside area of the beautiful city of Syracuse. Simply and tastefully furnished, with an unparalleled 360° view of the sea and a large terrace shaded by reeds where you can experience moments of relaxation and conviviality pieds dans l'eau.

Lovely apartment in the heart of Ortigia
In the heart of Giudecca, a stone's throw from the cathedral and the sea, on one of the most photographed streets of Ortigia. Elegant apartment, newly renovated, equipped with all the necessary amenities for your stay. Its strategic location on the island offers its guests an excellent central location but at the same time a quiet and peaceful stay.
Popular amenities for Santa Panagia holiday rentals
Other great holiday rentals in Santa Panagia

Spacious flat close to the sea! + Patio & parking

Cielo al Duomo, wide apt with terrace in Ortigia

Elegant apartment in the heart of Syracuse.

Aglaia apartment Ortigia Island terrace

Allisola Country Villa - casa Carrubo

Prime Ortigia |Soaring Ceilings Designer Interiors

Casa Santini Ortigia, 3 Bed 3 Bath, 1 min to Beach

Syracuse Ortigia Circe sul Mare
Destinations to explore
- Fontane Bianche Beach
- Calamosche Beach
- Etna Park
- Castello Ursino
- Fondachello Village
- Teatro Massimo Bellini
- Piano Provenzana
- Etnaland
- Castello Maniace
- Castello di Donnafugata
- Greek Theatre of Syracuse
- Villa Bellini
- Oasi Del Gelsomineto
- Sampieri Beach
- Nature reserve of Vendicari
- Isola delle Correnti
- Fishmarket
- Museo Emilio Greco
- Spiaggia Vendicari
- Temple of Apollo
- Aci Trezza
- Museo Archeologico Regionale Paolo Orsi
- Necropolis of Pantalica
- Noto Cathedral





