
Holiday houses in Santa Panagia
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Top-rated holiday rentals in Santa Panagia
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150sqm 2BA Prime Location Car Access Dining Guide
💎 Live the Sicilian Dolce Vita Newly renovated and thoughtfully designed, it blends historic elegance with modern comfort - placing you right at the heart of Ortigia’s timeless charm Why You’ll Love It 📍 Unbeatable Location – Steps from Piazza Duomo, local market 🚗 Rare Car Access – Easy luggage drop-off directly by the apartment 🏡 Elegant & Spacious – High ceilings, generous rooms 🌅 Stunning Views – 3 balconies overlooking Piazza Archimede 💡 Insider Tips – through our digital GuestGuide
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Penthouse Lady Packard
Lady Packard’s Penthouse just had a glow up!✨ A stunningly elegant, spacious and comfortable house with four levels, all above ground because of the sloping, pedestrian street on which it is built. Free parking is just steps away. The location is ideal, peaceful with amazing views, and just a few minutes’ walk from the city's center. The house sleeps 6 adults in 3 separate bedrooms. Perfect for a family holiday or a friends getaway, the common spaces comfortably accommodate everyone at once.
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Sea-View Loft. Elegant & Bright Old Town Retreat
Experience the timeless charm of Ortigia from this elegant 80 m² sea-view apartment. Perfect for couples, families, or small groups, Suite 18 blends authentic Sicilian character with modern comfort, just steps from the island’s iconic landmarks. Wake up to breathtaking harbour views from your private balcony, relax in the bright open-plan living area, and enjoy a fully equipped kitchen, a peaceful bedroom, and two modern bathrooms. Amenities include fast WiFi, A/C, heating and lift access.
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Brand new apartment with patio across Ortigia
Fully renovated modern apartment in proximity of Ortigia (6 mins walk) with free parking. With its three ensuite double bedrooms, the apartment can accommodate up to 6 people. All the rooms have aircon and 32' smart TV as same as the living room equipped with a 50' smart TV, a cozy couch and a few armchairs. A fully equipped kitchen and a patio to enjoy a glass of wine around a wooden table with your family and friends. Never wait around as you can check yourself in with the access code!
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Casa Santini Ortigia, 3 Bed 3 Bath, 1 min to Beach
On a quiet road a few steps away from the sea and Cala Rossa beach, this luminous independent 3 beds and 3 bathrooms townhouse, has been designed to make your holiday in Ortigia unforgettable. "CASA SANTINI" is the product of our family's love for Ortigia and the vision of our local Architect Ignazio. The house has been fully renovated with meticulous attention to details, keeping the old features and adding all comforts and modern elements to create an elegant and calming space.
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Casa Sirokos
Casa Sirokos è una villetta indipendente fronte piscina, immersa nel verde del quartiere residenziale più panoramico di Siracusa, caratterizzata da un'architettura locale che si fonde con ampi spazi esterni e giardini tipici della campagna siciliana. La villetta è uno dei due alloggi indipendenti che fanno parte di questa struttura, che propone anche un appartamento situato al primo piano di un'antica villa padronale. L'atmosfera sofisticata e rilassante ci contraddistingue!
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Light and Relaxation: Large Open-Plan Space Overlooking the Garden
Situato in un’ala riservata della villa con ingresso indipendente, questo open space di 95 mq unisce raffinatezza e modernità. Le ampie vetrate inondano di luce naturale gli ambienti, mentre l’arredamento definisce con naturalezza le diverse aree. Un perfetto equilibrio tra design, comfort e natura: gli spazi si fondono armoniosamente con il giardino, creando relax e privacy. Per motivi di sicurezza e comfort la struttura ospita bambini solo dai 10 anni compiuti in su.
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Casa Salgiò
Cozy and modern apartment on the outskirts of Syracuse, just a 10-minute drive from the historic center and in a well-served area. The apartment, completely renovated, consists of a living area with a double sofa bed, an equipped kitchenette, a bedroom, a small room with a bed, a bathroom with a shower, a storage room and a laundry area. The living room and bedroom overlook a veranda from which you can see glimpses of the sea and Mount Etna.
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Casa Sbarcadero
Casa Sbarcadero is just a 6-minute walk from the historic center of the island of Ortigia and about 20 minutes from the Neapolis archaeological area. The apartment offers access to the public solarium below, perfect for relaxing. The apartment consists of three bright rooms overlooking the small port, two bathrooms, a spacious living room and a well-equipped kitchen. The bus and train station is a 15-minute walk away.
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Comfortable apartment with reserved parking space
Apartment in an area well served by shops, supermarkets, bars, pizzerias, tobacconists, newsagents, bakery, bank and a characteristic street market with fish, fruit and typical products. Well equipped kitchen. Easily accessible by car and equipped with a reserved parking space inside a fenced condominium courtyard. The apartment is equipped with books and various touristic documentation on Sicily.
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Casa Francesca
Detached house directly located on the rocks in a private condominium context in the protected marine area of Plemmirio, in the seaside area of the beautiful city of Syracuse. Simply and tastefully furnished, with an unparalleled 360° view of the sea and a large terrace shaded by reeds where you can experience moments of relaxation and conviviality pieds dans l'eau.
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Lovely apartment in the heart of Ortigia
In the heart of Giudecca, a stone's throw from the cathedral and the sea, on one of the most photographed streets of Ortigia. Elegant apartment, newly renovated, equipped with all the necessary amenities for your stay. Its strategic location on the island offers its guests an excellent central location but at the same time a quiet and peaceful stay.
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Popular amenities for Santa Panagia holiday rentals
Other great holiday rentals in Santa Panagia

Ancient Greece House - Greek Theater
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Elegant apartment in the heart of Syracuse.
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Aglaia apartment Ortigia Island terrace
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Villa with pool + stunning views
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Timeless: Detached villa with infinity pool
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Maisonette, 14 San Paolo
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Cortile Crocefisso apartment
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Panoramic terrace in the historic soul of Ortigia
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Destinations to explore
- Fontane Bianche Beach
- Calamosche Beach
- Etna Park
- Castello Ursino
- Fondachello Village
- Piano Provenzana
- Teatro Massimo Bellini
- Etnaland
- Villa Bellini
- Castello Maniace
- Greek Theatre of Syracuse
- Castello di Donnafugata
- Nature reserve of Vendicari
- Oasi Del Gelsomineto
- Spiaggia Vendicari
- Sampieri Beach
- Fishmarket
- Isola delle Correnti
- Aci Trezza
- Museo Emilio Greco
- Necropolis of Pantalica
- Temple of Apollo
- Noto Antica
- Monastery of San Nicolò l'Arena





