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Holiday houses in Santo Domingo

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Top-rated holiday rentals in Santo Domingo

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Superhost
Cottage in Playa El Jobo
4.76 out of 5 average rating, 120 reviews

Disfruta una Casa de Playa frente al mar, patio

Playa El Jobo is a magical place, special for connecting with nature and resting. It is oceanfront at a height of 9 meters, which allows you to receive the cool sea breeze. The property has a wooden house with a first floor and an upper floor. On the ground floor you will find the kitchen, two full bathrooms, two outdoor showers and a covered space with hammocks. Upstairs there is a large balcony with hammocks, two bedrooms, a living area and two bathrooms. There is good lighting, natural ventilation and A/C

Superhost
Apartment in Las Tablas
5 out of 5 average rating, 4 reviews

Apartamento Coqueto y Confortable en las Tablas

Disfruta de una estancia premium en este elegante y acogedor apartamento en Las Tablas, diseñado para ofrecer comodidad, estilo y tranquilidad. El alojamiento cuenta con una decoración cuidada, para relajarse después de un día explorando la ciudad. Su excelente ubicación en Las Tablas te sitúa cerca de todos los puntos de interés convirtiéndolo en la opción perfecta tanto para estancias cortas como largas. ✨ Un espacio cómodo, moderno y con todo lo necesario para una experiencia inolvidable.

Guest favourite
A private pool is framed by a stone patio, surrounded by lush greenery and tropical plants. A shaded area features outdoor seating and a grill, while the enclosed space provides a sense of tranquility. The home is visible in the background, set against a clear blue sky.
Home in Pedasí
4.92 out of 5 average rating, 194 reviews

3 min to Pedasi, 5 min to the Beach, Private Pool!

Your family will be close to everything when you stay at this centrally-located place. Outfitted with room to sleep 6 and a fenced yard for your dog, Casa Catch and Relax has it all! Look us up online, Casa Catch and Relax You'll Love - Beach access a short drive or walk away (3 min drive, 10 min walk) - Central to town and local restaurants - Private, fenced outdoor space with pool - Cool days and nights with A/C in every room - Fully equipped kitchen and tons of sleeping space - Wifi

Top Guest favourite
Apartment in Las Tablas
5 out of 5 average rating, 12 reviews

Loft Conivan-Las Tablas

Disfruta de Las Tablas como en casa en este amplio y cómodo apartamento completo. Ubicado en un primer piso. Equipado para estancias cortas o largas, con cocina completa, sala acogedora, aire acondicionado y WiFi, ideal para todo tipo de viajeros. A pocos minutos encontrarás playas, restaurantes, supermercados y los principales puntos turísticos del pueblo. Ya sea que vengas por celebración, descanso, o paseo este alojamiento es el punto de partida perfecto para disfrutar Las Tablas.

Superhost
Apartment in Las Tablas
4.6 out of 5 average rating, 80 reviews

2nd floor Beach Apartment with Amazing Views!

Enjoy beach life all year round in Panama at Uverito Beach! Go to the beach anytime you want, it is literally at your footsteps or relax in a hammock. This 2 bedroom 1 bath 2nd floor unit has all the amenities that will make your stay comfortable. Long-term rental is also available plus electricity (except long-term rental of 28 days or more you pay), you get a smart TV, unlimited bandwidth Wi-Fi internet, hot water shower, and brand new kitchen appliances to include a dishwasher.

Superhost
A sunset view from the property captures golden rays casting soft light over lush greenery and distant hills. The vibrant hues of the sky blend into warm oranges and yellows, illuminating the surroundings, while the ocean can be faintly seen in the distance.
Cottage in Cañas
4.89 out of 5 average rating, 9 reviews

Bella Vista wooden house - near Playa Venao

Unique house in Los Santos! This home is a 60 years old Panamanian wooden house that's been renovated while still keeping its charm. 2 bedroom (main bedroom with king size bed, 2nd bedroom with twin size bed), 1 bathroom, fully equipped kitchen with spacious living and dining room. 1 closed and secure office with A/C with all the equipment needed (office chair, monitor, keypad...) A/C only in office, rest of house with fans! Papaya, our cat, lives in the house!

Guest favourite
Tiny home in Playa El Jobo
4.93 out of 5 average rating, 44 reviews

Private Beach Studio · Sunset & Nature Views

Designed for comfort, functionality, and a welcoming atmosphere: • Comfortable bed for a truly restful sleep • Air conditioning • Wi-Fi • Kitchen • 2 Bathrooms • Parking Perfect for short stays or longer breaks. Wake up at your leisure, enjoy a relaxing coffee, stroll to the beach, or simply unwind in this space. This place is ideal for: • Romantic getaways • Personal retreats • “Work from the beach” • Escaping the hustle and bustle of the city

Top Guest favourite
A sunlit outdoor area features wooden lounge chairs with thick cushions and matching umbrellas. A private pool is visible beside the deck, surrounded by landscaped greenery and steps leading to a charming house with large windows and a welcoming entrance.
Home in Playa Los Destiladeros
5 out of 5 average rating, 28 reviews

Pedasí, Los Destiladeros Beach / Casa Serena

❤ Welcome to Casa Serena, escape to our stunning 3-bedroom ocean view house, perfectly located in Playa Los Destiladeros, an area of ​​beautiful beaches in Pedasí. This unique retreat offers a blend of modern luxury and coastal charm, ensuring an unforgettable vacation experience for you and your loved ones. Book your stay today and experience the magic of Casa Serena. Create lasting memories with your family and friends in this perfect ocean view escape.

Guest favourite
A modern tropical home is set amid lush greenery, featuring an expansive deck that connects to a serene pool. Large glass doors provide a view of the inviting interior and allow natural light to fill the space. Mountains and trees frame the backdrop.
Home in Playa Venao
4.97 out of 5 average rating, 71 reviews

Casa Samambaia - sea view tropical paradise w pool

With a modern tropical design, this home features a cozy living room and a stylish kitchen at the center of the social area. Open the glass doors to immerse yourself in open-concept living, seamlessly blending the indoors with the main terrace and the pool, all oriented towards the ocean view. With two en-suite bedrooms with AC and fans, the house is immersed in nature, green mountains, and a lovely garden, everything 5 minutes from the beach center.

Guest favourite
The modern house is surrounded by lush greenery, featuring a spacious wooden deck with lounge chairs and a private pool. Sliding glass doors enhance the connection with nature, while a covered terrace provides shaded seating areas for relaxation.
Home in Playa Venao
4.92 out of 5 average rating, 72 reviews

Casa Pelicano - Tropical house w pool and seaview

Welcome to Casa Pelicano! Indulge yourself in a retreat with breathtaking views of the ocean and mountains from every corner. Unwind in the private refreshing pool, where the turquoise waters seem to blend seamlessly with the horizon. The stylish interior features open-plan living spaces, perfect for entertaining or relaxing. Whether you're soaking up the sun or gazing at the moonlit ocean under the stars, this home is your ultimate escape.

Guest favourite
A refreshing swimming pool sits in the foreground, complementing the rustic building behind it. Lush greenery and potted plants surround the area, enhancing the natural setting. A shaded patio area with outdoor seating is visible, offering a serene environment for relaxation.
Guesthouse in La Enea
4.96 out of 5 average rating, 51 reviews

Country House with Pool in La Enea de Guararé

Far from the capital city, come and enjoy Panamanian folklore in a rustic but cozy space, living an indigenous experience. Relax in the pool or rest in a hammock, breathe fresh air, near the sea, surrounded by spacious and natural gardens for a good walk. Close to the Port of Guararé where you can enjoy the best seafood and drinks or enjoy the heart of the best folklore event highlighting the traditions and the best Panamanian skirts.

Guest favourite
Place to stay in Pedasi
4.82 out of 5 average rating, 11 reviews

A Good Walk-Pedasi

Una Buena Caminata is a quiet, spacious villa designed as a retreat base—where days unfold slowly and logistics are handled with care. Set between the town center and Playa El Arenal, the gateway to Isla Iguana, the property offers both connection and seclusion in equal measure. This is not a resort and not a hands-off rental. It is an intentionally curated space for guests who value privacy, ease, and thoughtful living.

Popular amenities for Santo Domingo holiday rentals