
House holiday rentals in Seneca
Find and book unique houses on Airbnb
Top-rated house rentals in Seneca
Guests agree: These houses are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for Seneca house rentals
House rentals with a pool

Keowee Key Luxury Condo - Stunning Views!

Lakeside Family & Dog Retreat Awaits! DWC

Lakeside Retreat - 4BR/4BA Home

Lakefront, Private Pool, Dock, Dogs, Boats,FirePit

Keowee Lakeside with pool for 16

Golf view, lake access, 3 pools!

Historic peaceful 1906 Farmhouse

Lake Front w/Pool @ Tipsy Tiger Lake Hartwell
Weekly house rentals

The Canoe House - Family/Elder Friendly - Clemson

Pet-Friendly 5BR Getaway near Lake Keowee

Lake Hartwell Beauty with Dock. Minutes to Clemson

Waterfall Cove - Prime

Elderwood Escape near Clemson

Modern home near Clemson, Keowee

New! Charming 4/2.5 Modern Home in Clemson, SC

Cozy Modern Home Close Clemson
Private house rentals

Keowee Cottage: lakefront home

5BR*Lakefront*Games*Luxury*Dock

Lake Home & Treehouse ❤ Seneca Treehouse Project

Lake Keowee Lakefront Rental ,Kayaks, Dock, pets

Anchor Point, Lake Retreat - Clemson, 2-story dock

Creekside Escape~ pool table & sleeps 8

Lake House Retreat Near Clemson

Keowee Lakefront With Kayaks, Fire pits, & Dog Run
Quick stats about house rentals in Seneca
Total rentals
30 properties
Nightly prices starting at
$67 NZD before taxes and fees
Total number of reviews
1.6K reviews
Family-friendly rentals
20 properties are a good fit for families
Pet-friendly rentals
10 properties allow pets
Rentals with dedicated workspaces
10 properties have a dedicated workspace
Destinations to explore
- Western North Carolina Holiday rentals
- Nashville Holiday rentals
- Atlanta Holiday rentals
- Myrtle Beach Holiday rentals
- Charleston Holiday rentals
- Gatlinburg Holiday rentals
- Charlotte Holiday rentals
- Hilton Head Island Holiday rentals
- Savannah Holiday rentals
- Pigeon Forge Holiday rentals
- Cape Fear River Holiday rentals
- North Myrtle Beach Holiday rentals
- Rentals with outdoor seating Seneca
- Rentals with a patio Seneca
- Rentals with a washing machine and dryer Seneca
- Rentals with a fire pit Seneca
- Pet-friendly rentals Seneca
- Rentals with lake access Seneca
- Cabin rentals Seneca
- Lakehouse rentals Seneca
- House rentals Oconee County
- House rentals South Carolina
- House rentals United States
- Cabins United States
- Treehouses United States
- Tiny Houses United States
- Beach Houses United States
- Lakehouses United States
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
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- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Black Rock Mountain State Park
- Gorges State Park
- Helen Tubing & Waterpark
- Table Rock State Park
- Mountaintop Golf & Lake Club
- Tugaloo State Park
- Tallulah Gorge State Park
- Bell Mountain
- Ski Sapphire Valley
- Don Carter State Park
- Jump Off Rock
- Wade Hampton Golf Club
- Victoria Valley Vineyards
- Anna Ruby Falls
- Victoria Bryant State Park
- Funopolis Family Fun Center
- Old Edwards Club
- Carl Sandburg Home National Historic Site
- Haas Family Golf
- Discovery Island
- Louing Creek