
House holiday rentals in Seneca
Find and book unique houses on Airbnb
Quick stats about house rentals in Seneca

Total holiday rentals
Explore 40 holiday rentals in Seneca

Nightly prices starting at
Seneca holiday rentals start at $85 NZD per night before taxes and fees

Verified guest reviews
Over 1,880 verified reviews to help you choose

Family-friendly holiday rentals
30 properties offer extra space and kid-friendly amenities

Pet-friendly accommodation
Find 10 rentals that welcome pets

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wi-Fi availability
40 of Seneca holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Seneca rentals

4.9 Average rating
Seneca stays are highly rated by guests—averaging 4.9 out of 5!
Top-rated house rentals in Seneca
Guests agree: These houses are highly rated for location, cleanliness and more.

Modern Lake Vibes – Kayaks, Dock & Fireplace
The perfect home for lake lovers and college football fans. Located just ~5 minutes away from Clemson and Death Valley, the newly renovated lakefront cottage will be the perfect stay for you, your family, and friends. With an outdoor fire pit, amazing views, boat dock, kayaks, and a modern kitchen, this retreat has all the amenities you're looking for inside and out! Whether you spend your time relaxing at the house, cheering on the Tigers, or fishing the lake, the Hideaway is sure to please.
LocationFamilySleep quality

Dujardins Keowee Waterfront Home
2 night min. Deep water lot on Lake Keowee with double dock, and tons of entertaining space. On the main level, the great room/dining room is open to the kitchen. 4 bedrooms total, 3 king bedrooms (2 on first floor), 1 king and a bunk room with 2 doubles and 2 singles. A canoe, 2 paddle boards and 2 double kayaks included. Shuffleboard, foosball, outdoor Ping-Pong, board games and two person pac-man game, with additional 60 games! towels and linens included! Pickleball/tennis 10 min away!
LocationValueKitchen

Private lake setting close to Clemson University
House is located in a private community yet only 2.5 miles to Death Valley and Clemson. Enjoy a walk down to the lake or relax on the back deck. WIFI is included with access to Hulu and Disney+. Kid friendly as well. Property is also within 1.2 miles of Oconee Airport, 0.7 miles to a dock, 1.5 miles to the grocery store, and less than 1.3 miles to Y beach public parking (avoid game day traffic if you are coming in for football). Close to everything in Oconee, Pickens and Anderson Counties.
ValueFamilyNearby

Waterfall Views, Lake Hartwell, Highland Architect
Come and enjoy nature with 100+ acres to roam. Architect James Fox designed this cantilevered cliffside home overlooking a beautiful waterfall. Feel like you are in the trees, in an area much as it was when inhabited by Cherokee Indians. Stream feeds into Lake Hartwell. In the summer months on the weekends and holidays kayaks, jet skis and small boats visit the falls. This property is in the foothills of the Appalachian Mountains. Please respect our pet policy, only service animals.
FamilyValuePool

The Cozy Cottage
Beautiful, well-maintained home located in a private subdivision just minutes away from shopping, restaurants, lakes, golf courses, and Clemson University. This home has a fully equipped kitchen for dining in and a back patio for grilling out. The backyard overlooks a peaceful wooded area, providing a serene and private escape. Our home offers the perfect blend of tranquility and convenience. Perfect for getaways, football weekends, graduation, and other Clemson University events!
ValueFamilyView

Singing Pines Cottage
Right among the pines of South Carolina you will find our cottage. It's 5 minutes from the Historic Ram Cat Alley with Live Outdoor music every Thursday Night (Apr.-Oct.), Shopping, Boutiques, Restaurants, Breweries, and Coffee Shops. It's only 12 minutes from Clemson University, and a short drive to Lake Keowee, Lake Jocassee, and Lake Hartwell. This area is home to numerous Waterfalls, Hiking Trails, and good southern barbecue. We do not host work crews.
FamilyLocationSleep quality

The Cottage
Relax, recharge, and enjoy the quiet. Unwind on the front porch as the sun sets and nature comes alive with the peaceful sounds of evening. Spend time by the pond and cast a line for a simple, relaxing escape (fishing poles not provided). Private and serene, yet just 5 minutes to Walmart and Oconee Memorial Hospital—and only 13 miles to Clemson. The perfect blend of tranquility and convenience. Minimum age to book is 25 years of age.
FamilyValueAccuracy

Shady Rest
As you enter the screened in front porch you will instantly relax, experience a peaceful and quiet tree lined front yard. The house has plenty of shade and old oaks, built in 1935 has the charm of visiting great grandmother’s farm house without the wallpaper. Large side deck with grill, hot tub and plenty of shaded sitting. Side yard has a fire pit for evening campfires and roasting marshmallows. The house has an open floor plan.
LocationValueCleanliness

Hidden Lake Sanctuary
Recently remodeled with over 3,000 sq ft of comfortable living space, this peaceful retreat is tucked away in a quiet cove. Enjoy a large, fully stocked kitchen, spacious private deck, and relaxing hot tub. The property includes 2 kayaks and 2 paddleboards for exploring the cove. The path to the private dock is steep and best suited for active guests. Bringing a boat? A nearby public launch makes it easy to get out on the lake.
ValueFamilyGetting around

Getaway on Lake Hartwell: Pontoon Rental, Clemson
Our 3 bedroom house is located on Lake Hartwell and is just a 15 min drive to Clemson University. You can enjoy access to the dock and beach which are a quick golf cart ride away. We have paddle boards on the dock and kayaks, coolers, bagged ice, fishing poles etc upon request. Off the back of the detached garage there’s a furnished screened-in deck with a grill that overlooks the end of the cove and fire pit below.
LocationFamilyPets

5 Min to Clemson | Large Driveway & Self Check-In
Welcome to your Cozy Family Home! Escape to this charming 3-bedroom, 2-bathroom home, just a short 3-mile drive from the iconic Clemson Memorial Stadium. Whether you're planning a trip to the lake, tailgating for the big game, catching up with friends, or exploring the local hiking trails, this quiet and convenient home is your ideal base. Can't wait for you to enjoy Clemson, SC. Go Tigers! Pet Fee of $100.
FamilyLocationPets

The House on Oak Grove
Enjoy your time spent in this spacious and peaceful pet friendly space. Nicely appointed with everything you need for a short or long term stay. Ten easy miles to Clemson and 3 miles to SWU. Besides the open living space the house has a screened porch and accomodates 4 with 2 bedroom & 2 adjoining baths. The home includes washer & dryer, coffee bar, granite countertops, and microwave.
FamilyLocationSleep quality
Popular amenities for Seneca house rentals
House rentals with a pool

Keowee Key Luxury Condo - Stunning Views!
ValueFamilyCheckout

Lakeside Retreat • Pet friendly • Fire Pit
LocationFamilyHospitality

Lake house w/ a pool and Pickleball court
FamilyLocationHiking

5 Min to Clemson | Pool | Hot Tub | Sports Lounge
LocationValueLayout

The Hilltop Hideaway at Lake Hartwell
LocationFamilyDecor

See you soon Keowee Kustom!*NO Dock!
FamilyLocationKitchen

Cottage close to Clemson with private pool!
LocationFamilyAccess

Clemson Games + ON Lake Hartwell
LocationFamilyWi-Fi
Weekly house rentals

Lake Hartwell house w/ dock 2 miles from Clemson.
FamilyLocationBathroom

The Carriage House at South Townville
LocationFamilyCondition

Lakefront Mid-Century Dream Home / 3 mi to Clemson
ValueLocationOutdoor spaces

Cozy Modern Home Close Clemson
FamilyLocationComfort

Peaceful Lake Keowee Waterfront Home ~Near Clemson
FamilyValueIndoor spaces

Valhalla: Cliff-Edge Suite · Forest Views · Tub
ValueFamilyNearby

Lakefront Home w/Deep Water Dock 20 min to Clemson
FamilyLocationOutdoor spaces

The Landing Spot
LocationValueGetting around
Private house rentals

Lakefront Getaway~Dock~Fire Pit~Kayak & Games!
FamilyLocationView

Retreat w/ Dock & Hot Tub at Martin Creek
LocationValueComfort

Mountain Road Cottage
LocationFamilyHeating

Point Lot, Boat and PWC Rental
LocationValueHot tub

Cozy Lake Home with Dock. Close to Clemson.
FamilyLocationDecor

Johnsons Cove - Lakefront Retreat With EV Charger
FamilyValueOutdoor spaces

Lakefront Escape w/ Private Dock
FamilyLocationTV

Frankie’s Place
ValueLocationComfort
When is the best time to visit Seneca?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sept | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | $290 NZD | $342 NZD | $323 NZD | $331 NZD | $432 NZD | $601 NZD | $278 NZD | $401 NZD | $371 NZD | $331 NZD | $396 NZD | $308 NZD |
| Avg. temp | 6°C | 8°C | 12°C | 16°C | 21°C | 25°C | 27°C | 26°C | 23°C | 17°C | 11°C | 7°C |
Destinations to explore
- Nashville Holiday rentals
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- Charleston Holiday rentals
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- Hilton Head Island Holiday rentals
- North Myrtle Beach Holiday rentals
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- Louisville Holiday rentals
- Clemson University
- Table Rock State Park
- Black Rock Mountain State Park
- Devils Fork State Park
- Gorges State Park
- Tallulah Gorge State Park
- Helen Tubing & Waterpark
- DuPont State Forest
- Bell Mountain
- Unicoi State Park and Lodge
- Bon Secours Wellness Arena
- Ski Sapphire Valley
- Looking Glass Falls
- Chattooga Belle Farm
- Fred W Symmes Chapel
- Jump Off Rock
- Dillard House Restaurant
- Fluor Field at the West End
- Jones Gap State Park
- Dry Falls
- Falls Park On The Reedy
- Peace Center
- Anna Ruby Falls
- Carl Sandburg Home National Historic Site





