
Boutique hotel holiday rentals in Saint Louis County
Find and book unique boutique hotel rentals on Airbnb
Top-Rated Boutique Hotels in Saint Louis County
Guests agree: These boutique hotel rentals are highly rated for location, cleanliness and more.

Chic Ultramodern Studio Loft w/ Designer Features
The Nash Loft is a stunning minimalist studio with 12’ ceilings, a fully-equipped kitchen with black stainless appliances and quartz countertops, a spacious walk-in closet, stackable washer + dryer, a designer bathroom with black stainless fixtures and frameless glass shower, and bright 7’ industrial steel-frame windows with views of the tree-lined street and shops below. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

Chic Ultramodern Studio Loft w/ Designer Features
The Nash Loft is a stunning minimalist studio with 12’ ceilings, a fully-equipped kitchen with black stainless appliances and quartz countertops, a spacious walk-in closet, stackable washer + dryer, a designer bathroom with black stainless fixtures and frameless glass shower, and bright 7’ industrial steel-frame windows with views of the tree-lined street and shops below. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

The West End by Cortex, Forest Park, BJC & Zoo
Welcome to The West End, your ideal retreat in the heart of the Central West End! Just steps away from charming attractions like forest park. Great amenities are: - Fast and stable fiber internet connection - Communal kitchen with 2 sets of range, ovens, fridges, microwaves, and dishwashers. - Complimentary coffee - Secured Gated Parking $10/Night - Hot Tub - Great patio space with seating and a gas grill - Complimentary Netflix, Hulu, Disney+, and ESPN+, where available and local TV channel

#3 Betty Bloomer Le Velo Inn
Enter to a grand staircase adorned with a chandelier. Upstairs, find a king-size bed with a distinctive wall made of doors and bicycle rims, separating the open staircase and bedroom. This vibrant oasis features splashes of color for added glam. The charm of exposed brick and unique design elements make the space boujee. A custom headboard of antique doors is a focal point. A small workspace with a view of French St. and refinished hardwood floors from the building's origins complete the unit.

Chic Ultramodern Minimalist Studio Loft + Patio
The Nash Loft is a stunning minimalist studio with 12’ ceilings, a fully-equipped kitchen with black stainless appliances and quartz countertops, stackable washer + dryer, a designer bathroom with black stainless fixtures and frameless glass shower, a comfortable workspace with high-speed internet connection, bwalk-in closet, and a lovely patio overlooking the courtyard. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

Three Bedroom River View Guest House-3 Bathrooms
An escape from the ordinary in our River view guest house. On bottom level is an art glass shop offering classes in stained , fused, and mosaic art glass you may partake in at an additional cost. Bicycle built for two available for cycling the national scenic byway. Walk to shops, casino, restaurants, breweries, and concerts. Cruise ship dock is 1/2 mile away. Extend your stay before or after to enjoy taking a stained glass class offered in our shop below as a souvenir of your trip.

Luxury Retreat, Hot Tub,En-Suite Bath, Location+
Discover refined elegance in The Riverfront Suite, where Gothic grandeur meets contemporary comfort. This distinctive retreat showcases original stained glass windows and exotic wood finishes . A plush queen bed and ambient electric fireplace create an intimate atmosphere, while the luxurious en-suite bathroom features heated floors, designer tile work, and a 2-person soaking tub. Take in panoramic city views from the shared rooftop hot tub. Perfect for couples seeking a romantic escape.

The Best of Suite Living! Ideal for Work & Leisure
By staying at our property, you can make the most of your trip, whether it's for work or pleasure. We are conveniently located near renowned destinations including Hanley Park, the St. Louis Children's Aquarium, and Oak Tree Park in the Brentwood neighborhood. We are close to Whole Foods Market, Applegate's Deli, and Camille's Sidewalk Cafe, among other well-known restaurants. You can grab a free breakfast in the morning and get a head start on your day. Enjoy the free parking and Wi-Fi.

The Maple Room Queen Bed at BnB in CWE!
A Lovely room in a historical St. Louis home! The Blue Spruce Room is on the 2nd floor, and has a recently renovated and beautiful bathroom complete with a walk-in rain shower right next to it. The room has a desk, chair, lamp, table, Amazon Fire TV with basically every major streaming App, newly installed hardwood floors, and a Queen sized-bed. The room has two large windows for plenty of natural light with heavy blinds for sleeping in! Full use of the kitchen upstairs is available!

Chic Ultramodern Studio Loft w/ Designer Features
The Nash Loft is a stunning minimalist studio with 12’ ceilings + bright 7’ industrial steel-frame windows, a spacious open layout, stackable washer + dryer, a designer bathroom with black stainless fixtures and frameless glass shower, an Edison-illuminated community courtyard, and a fully-equipped kitchen with black stainless appliances and quartz countertops. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

Gorgeous Ultramodern 2BR Corner Loft + Workspace
The Nash Loft is a stunning corner loft with two spacious bedrooms, two designer bathrooms with black stainless fixtures and frameless glass showers, 12’ ceilings, a comfortable workspace with high-speed internet connection, stackable washer + dryer, an Edison-illuminated community courtyard, and a fully-equipped kitchen with black stainless appliances. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

Penthouse Suite
Room 301 2 bedroom Queen, King room Oak Street Inn & Lounge, 8 Room Boutique hotel situated in the bustling center of downtown Cottleville. Oak Street Inn & Lounge will offer an elegant restaurant and craft cocktail lounge on the ground floor Indulge in room service from Pink Willow Cafe, or dine in! Come up to the rooftop patio on the third level for a cocktails, small bites and breathtaking views of Cottleville. Look for our Hidden Gem the Speakeasy in the lower level!
Popular amenities for Saint Louis County Boutique Hotels
Family-Friendly Boutique Hotels

Chic Ultramodern Loft Suite w/ Designer Features

Chic Ultramodern Studio Loft w/ Designer Features

Chic Ultramodern Studio Loft w/ Designer Features

Chic Ultramodern Minimalist Loft Suite + Patio
Boutique Hotels with a patio

1st Capitol Mansion Boutique Hotel - Suite 301

Luxury Retreat, Hot Tub, En-Suite Bath, Location+

Luxury Retreat, Hot Tub,En-Suite Bath, Location+

#6 The Green Tyke Le Velo Inn

#4 – Penny Farthing Le Velo Inn

Luxury Retreat, Hot Tub,En-Suite Bath, Location+
Other boutique hotel holiday rentals

King Redwood Bedroom at BnB in CWE!

Blue Spruce Room Queen Bed at BnB in CWE!

Chic Ultramodern Studio Loft w/ Designer Features

Chic Ultramodern Studio Loft w/ Designer Features

Evergreen Room Queen Bed at BnB in CWE

Chic Ultramodern Studio Loft w/ Designer Features

The Maple Room Queen Bed at BnB in CWE!

Chic Ultramodern Studio Loft w/ Designer Features
Destinations to explore
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- Boutique hotel rentals Missouri
- Boutique hotel rentals United States
- Busch Stadium
- Six Flags St. Louis
- Central West End
- Saint Louis Zoo
- Enterprise Center
- City Museum
- Missouri Botanical Garden
- Cuivre River State Park
- St. Louis Aquarium at Union Station
- Pere Marquette State Park
- Meramec State Park
- Castlewood State Park
- The Winery at Aerie's Resort
- Hidden Valley Ski Resort
- Cathedral Basilica of Saint Louis
- Grafton Winery the Vineyards
- Norwood Hills Country Club
- Raging Rivers WaterPark
- Saint Louis Science Center
- Adventure Valley Zipline Tours and Paintball Park
- Bellerive Country Club
- Missouri History Museum
- Boone Valley Golf Club
- Old Warson Country Club