Boutique hotel holiday rentals in Missouri

Find and book unique boutique hotel rentals on Airbnb

Top-Rated Boutique Hotels in Missouri

Guests agree: These boutique hotel rentals are highly rated for location, cleanliness and more.

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Guest favourite

Hotel room in Washington

4.95 out of 5 average rating, 116 reviews

River Sirens Hotel Deluxe Suite

11 Room Boutique Hotel in beautiful Downtown Washington. Each room has: Private Entrance Guest Access - Key Pad, Free Parking, King Size bed, TV, Wifi, Hair Dryer, Individual A/C & Heat. Guests can enjoy a shower room featuring a changing area with separate vanity and water closet spaces. Every room as a very large balcony with river views. Each room is also equipped with a full kitchen featuring large refrigerators w/ ice dispensers, induction stove top, microwave, toaster, and coffee station.

Guest favourite

Hotel room in Kansas City

4.82 out of 5 average rating, 11 reviews

Kersey Coates at Southmoreland on the Plaza

Southmoreland is a historic 1913 Mansion whose goal is to provide hospitality and comfort. It is conveniently located in the heart of Kansas City’s Country Club Plaza. If your goal is to find a unique alternative to the classic downtown hotel, then look no further! The main floor boasts a living room with a gas fireplace and wet bar, a dining room with a lengthy wood table and a sunroom with a porch swing. The veranda is lined with floor to ceiling windows overlooking the garden in summer.

Guest favourite

Hotel room in Osceola

4.92 out of 5 average rating, 91 reviews

Historic Commercial Hotel(1868),Sally Rand Suite

The Historic Commercial Hotel (Est.1868) on the Downtown square in beautiful Osceola,Missouri. Old world feel with modernized accommodations. The Historic Commercial Hotel has numerous themed rooms which are designed and named after past historical guests. This specific room is "The Sally Rand Suite". Named after past historical guest Sally Rand ( 1904 – 1979) who was an American burlesque dancer and Silver Screen star, most noted for her ostrich feather fan dance and balloon bubble dance.

Guest favourite

Hotel room in Springfield

4.95 out of 5 average rating, 197 reviews

“Camp Rockwood”at Rockwood Motor Court on Route 66

Rockwood Motor Court, on historic Route 66, was built in 1929. Each room is themed and furnished to the era of Route 66. Camp Rockwood pays homage to the important history of motor courts along the road. It is decorated with historic photos of Rockwood and other courts and motels. Newly renovated in 2019, you’ll enjoy clean and comfortable room amenities while experiencing authentic motor court lodging. Need more space? We have larger rooms or can package multiple rooms for your group.

Guest favourite

Hotel room in Excelsior Springs

4.94 out of 5 average rating, 16 reviews

Beautiful Historic Suite

The Hope Loft Suite, located on the second floor of Casa Di Vite International Wine Café," in Excelsior Springs, Missouri, offers a delightful place to stay. This exquisitely furnished loft is crafted to reflect the style of the early 1900s, featuring a generous king-size bed and an additional room with a twin-size bed. Its location in historic downtown Excelsior Springs ensures easy access to diverse dining choices and shopping experiences. A private staircase in the back offers access.

Guest favourite

Hotel room in Eldon

4.89 out of 5 average rating, 19 reviews

#9 A 1930’s motor court, Historic Randles Court

Family owned and operated! Built in the early 1930s, our recently restored rooms will take you back to simple times. The days of bus & railway rest stops, road-trips in the family car, and the quintessential motor court -the era of the Great American Motel. Our town is alive with new and old businesses alike - places to eat, shop, and play for everyone in the family! We’re centrally located in downtown Eldon-just 15 minutes from the Lake of the Ozarks and 30 minutes from Jefferson City.

Superhost

Hotel room in Springfield

4.88 out of 5 average rating, 33 reviews

Culture Boutique Hotel: Pokhara Suite

We're located on Historic C-Street, home to artisan shops, Askinosie, a farmer’s market, yoga studios, wedding venues + more. Downstairs from our hotel is our very own coffee shop! Our loft-like suites feature furniture made from reclaimed materials from our building, a converted mattress factory. Each suite is inspired by a city in Eurasia. The rooms boast high ceilings, a 39in tv, a refrigerator, microwave and a V60, Electric Kettle, + complimentary coffee from Eurasia Coffee & Tea.

Guest favourite

Hotel room in St. Louis

5 out of 5 average rating, 10 reviews

Luxury Retreat, Hot Tub,En-Suite Bath, Location+

The Hill Suite is a luxurious escape in the heart of St. Louis. With its wood finishing, colorful stained-glass windows, and gothic architecture, this retreat offers a serene escape in St. Louis's historic Clifton Heights neighborhood. Sink into a plush queen bed, enjoy a spacious en-suite bathroom with heated floors, luxury tile and soaking tub. Don't miss out on shared access to the rooftop hot tub for ultimate relaxation! Perfect for a romantic getaway or a tranquil retreat.

Guest favourite

Hotel room in Hannibal

4.96 out of 5 average rating, 118 reviews

The Woodsman Suite

A third floor suite, facing the river with the train tracks only a couple blocks away. It took 2 months to do the ceiling. Carefully polished and placed the old lath in a specific design, the ceiling is a work of art. Eighty percent of the material used in this room is from re purposed lumber, either from this building or from a childhood barn built in the late 1800's. It will take you a while to notice every detail down to the toilet paper holder which is from an old barn post.

Guest favourite

Hotel room in Hollister

4.92 out of 5 average rating, 107 reviews

Vintage Creekside Motel in Hollister MO (09)

Enjoy easy access to popular shops and restaurants from this charming vintage hotel in Downtown Hollister. We are also only one mile from Branson Landing/downtown Branson. Room 9 is on the front of the building and is a walk in unit. There is a queen bed in the front room and a king bed in the back room where the bathroom is. There is a wet bar area with a fridge, microwave, coffee pot, keurig, and a few plates, bowls, cups, mugs, and utensils. We prove the coffee and creamer.

Superhost

Hotel room in Pacific

4.86 out of 5 average rating, 14 reviews

Captain two room on the first floor sleeps 2

First floor room with a cozy queen bed. Your room has a full bathroom with walk in shower, tv, desk, and mini fridge. There is a Community kitchen in the dining area where you are welcome to store and prepare food. Breakfast items available in the community kitchen daily. All the breakfast items are located in labeled bins. Please only 1 medium to large dog.

Guest favourite

Hotel room in Saint Louis

4.9 out of 5 average rating, 878 reviews

King Redwood Bedroom at BnB in CWE!

This is the largest of the rooms we have at our CWE BnB - an historic house in St. Louis' premier neighborhood. It has one King sized bed, a pullout sleeper sofa, two back-to-back 45" 4K Smart TVs with Rokus, and bathroom and kitchen space shared with guests of other rooms on this floor. Within a short walk of the basilica and many bars and restaurants in the CWE!