Vacation rentals in Cape Girardeau

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Top-rated holiday rentals in Cape Girardeau

Guests agree: these stays are highly rated for location, cleanliness, and more.

Guest favourite
Apartment in Cape Girardeau
Beautiful Historic Boulevard District Apartment
This beautiful, private upstairs apartment is located on a favorite street in Cape Girardeau’s Historic Boulevard District. It is walking distance to SEMO University, Capaha Park, and the downtown riverfront. Recently remodeled for laundry, spacious rooms offer private bedroom spaces and a cozy den for watching movies or reading. The kitchen is fully equipped with amenities. This quiet neighborhood setting even has a front porch swing and sitting area where you can enjoy your morning coffee.
30 Aug – 6 Sep
$190 NZD per night
4.97 out of 5 average rating, 339 reviews
Guest favourite
Guest suite in Cape Girardeau
MAINSTAY CAPE [downtown]
Nestled in the heart of the Downtown Historic District, this suite is centrally located as a prime destination for any and all travelers alike. With parking available, this space offers a unique & trendy “midwest boho” vibe. ~WALKABLE~ Our studio is 1 block from the bustling Southeast Missouri State University, 1 block from the gorgeous Capaha Park, and 2 blocks from Mercy Hospital. If you are interested in night life, this space is simply a 5-10 minute walk to all DT bars and restaurants.
12–19 May
$145 NZD per night
4.96 out of 5 average rating, 103 reviews
Guest favourite
Apartment in Cape Girardeau
Brand new 2 bedroom unit right in downtown Cape.
This special place is close to everything, making it easy to plan your visit. Walking distance to restaurants, the river and nightlife. Property includes wifi, full kitchen, laundry, deck and private parking for one. One king bed room and a twin bed room in addition to a roll out twin bed along with a 60 inch smart television. Dog bed and bowls included along with board games! Property is conveniently located across the street from "The Bar" the famous spot from the movie "Gone Girl" .
26 Dec – 2 Jan
$220 NZD per night
4.94 out of 5 average rating, 163 reviews

Popular amenities for Cape Girardeau holiday rentals

Stay near Cape Girardeau's top sights

Capaha Park4 locals recommend
Dogwood Social House3 locals recommend
Port Cape13 locals recommend
Katy O'Ferrell's Publick House9 locals recommend
Mary Jane bourbon + smokehouse7 locals recommend
Pilot House Restaurant & Catering3 locals recommend

Other great holiday rentals in Cape Girardeau

Guest favourite
Cottage in Cape Girardeau
Historic Cottage Walkable to Downtown Cape
13–20 Jun
$311 NZD per night
4.98 out of 5 average rating, 170 reviews
Guest favourite
Home in Jackson
*County Club 439*
13–20 Aug
$449 NZD per night
4.94 out of 5 average rating, 108 reviews
Guest favourite
Home in Cape Girardeau
The Hamilton House
21–28 Jun
$188 NZD per night
4.98 out of 5 average rating, 343 reviews
Guest favourite
Home in Cape Girardeau
River Run
26 Apr – 3 May
$423 NZD per night
4.97 out of 5 average rating, 116 reviews
Guest favourite
Place to stay in Cobden
Eva's Roost Retreat - Center For Lost Arts
25 Jun – 2 Jul
$199 NZD per night
4.95 out of 5 average rating, 266 reviews
Guest favourite
Guesthouse in Cape Girardeau
Cozy 1-BR guest house w/free parking on premises
6–13 Feb
$137 NZD per night
4.94 out of 5 average rating, 51 reviews
Guest favourite
Treehouse in Cape Girardeau
Twisted Sassafras Treehouse
15–22 Jan
$481 NZD per night
4.98 out of 5 average rating, 48 reviews
Guest favourite
Apartment in Cape Girardeau
Private Downtown Apartment
24–31 Dec
$219 NZD per night
4.97 out of 5 average rating, 58 reviews
Guest favourite
Home in Cape Girardeau
House Of Clubs- 2 Bed 1.5 Bath
28 Dec – 4 Jan
$259 NZD per night
4.95 out of 5 average rating, 62 reviews
Guest favourite
Tiny home in Jackson
The Cottage, Rusted Route Farms
26 Mar – 2 Apr
$284 NZD per night
5.0 out of 5 average rating, 13 reviews
Guest favourite
Home in Cape Girardeau
Elegant Home Near Hospital
4–11 Nov
$250 NZD per night
4.84 out of 5 average rating, 19 reviews
Guest favourite
Barn in Cape Girardeau
Under the Stars - Farmhouse
26 Oct – 2 Nov
$379 NZD per night
4.95 out of 5 average rating, 91 reviews

Quick stats about holiday rentals in Cape Girardeau

Total rentals

140 properties

Rentals with dedicated workspaces

90 properties have a dedicated workspace

Pet-friendly rentals

40 properties allow pets

Family-friendly rentals

60 properties are a good fit for families

Total number of reviews

8K reviews

Nightly prices starting at

$32 NZD before taxes and fees

Destinations to explore