Apartment holiday rentals in Cape Girardeau

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Top-rated apartment rentals in Cape Girardeau

Guests agree: These apartments are highly rated for location, cleanliness and more.

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Top Guest favourite
A view from the front porch showcases a vibrant autumn scene, with trees covered in golden leaves. A cozy seating area is visible, framed by white railings, and a peaceful street with fallen leaves creates a calm atmosphere.
Apartment in Cape Girardeau
4.98 out of 5 average rating, 447 reviews

Beautiful Historic Boulevard District Apartment

This beautiful, private upstairs apartment is located on a favorite street in Cape Girardeau’s Historic Boulevard District. It is walking distance to SEMO University, Capaha Park, and the downtown riverfront. Recently remodeled for laundry, spacious rooms offer private bedroom spaces and a cozy den for watching movies or reading. The kitchen is fully equipped with amenities. This quiet neighborhood setting even has a front porch swing and sitting area where you can enjoy your morning coffee.

Top Guest favourite
A spacious living area features large windows allowing natural light to fill the space. A comfortable grey sofa is paired with a unique coffee table, while stylish dining chairs surround a white table. The kitchen area includes modern appliances and cabinetry.
Apartment in Cape Girardeau
4.95 out of 5 average rating, 284 reviews

Brand new 2 bedroom unit right in downtown Cape.

This special place is close to everything, making it easy to plan your visit. Walking distance to restaurants, the river and nightlife. Property includes wifi, full kitchen, laundry, deck and private parking for one. One king bed room and a twin bed room in addition to a roll out twin bed along with a 60 inch smart television. Dog bed and bowls included along with board games! Property is conveniently located across the street from "The Bar" the famous spot from the movie "Gone Girl" .

Top Guest favourite
A view from above captures the full kitchen equipped with electric appliances, including a refrigerator and stovetop. The wooden floor is complemented by colorful area rugs, and natural light brightens the space. Shelves and cabinetry are neatly arranged in the background.
Apartment in Carbondale
4.95 out of 5 average rating, 63 reviews

Regal Rustic Retreat

Take it easy at this unique and tranquil getaway. Close to SIU Carbondale and also Murphysboro. We offer a quiet, simple apartment to relax and recharge. Free local over the air television. We have broadband/smart monitor for your HDMI stick . Bring your own Roku or Firestick with your subscriptions. The second bedroom is an open loft area, not a separate room. We offer a large storage space for bicycles and mudroom with washer/dryer for cleaning up after a hike or bike race. Full kitchen.

Top Guest favourite
The building features classic brick architecture with ornate ironwork detailing on the balcony. A large clock is positioned on the exterior wall. Nearby streets and parked vehicles are visible, along with a clear blue sky providing a bright backdrop.
Apartment in Cape Girardeau
4.98 out of 5 average rating, 105 reviews

Historical Kage House

The Building is reminiscent of eighteenth-century New Orleans architecture, and was built sometime before 1883. The Kage House is located at 120 Broadway in the historical district and is less than a minutes walk to Main Street and less than a 10 minutes walk to the Isle of Capri Casino. On Main Street you will find many fine shops and restaurants, or just enjoy the scenic area as you walkabout. This is by far one of the best places in Cape. Additional reviews can be read on the VRBO website.

Guest favourite
A serene view of the Mississippi River is presented, highlighting the tranquil water and the pavilion that juts into the river. Lush green grass borders the water, and trees line the distant shore, creating a natural landscape under a clear sky.
Apartment in Scott City
4.96 out of 5 average rating, 48 reviews

RiverSide Barn Suite on the Mississippi River.

The barn suite is a beautiful 2 bedroom apartment overlooking the Mississippi River and housed in a unique barn with its own separate entrance. The deck views are spectacular and takes sitting and relaxing to a new level. Our wine place “The RiverHouse “ is within walking distance with the best worldwide wines and menu in the area. www.theriverhousewineplace.com We are 12 minutes from Cape Girardeau and serviced by Lyft & Car-Go. You May contact us by text or call and available at any time.

The entrance features a welcoming front porch with a white bench and colorful flower pots. A vibrant arrangement of yellow daffodils blooms along the walkway, enhancing the inviting appearance of the home. The exterior is characterized by a combination of white brick and gray siding.
Apartment in Cape Girardeau
4.88 out of 5 average rating, 101 reviews

Visit the "Gone Girl" neighborhood

Living rm/bedrm, full kitchen, ADA bath, and walk in closet. Fully equipped with dishes,linens, refig, micro,stove, keurig, dishwasher and welcome home snacks. Double Murphy bed, queen hide a bed couch convert the living room to bedroom. Space is good for up to 3 adults, 2 adults and 2 children or a single guest. We accept well mannered dogs up to 50 pounds. We do not accept CATS. Like cats but they cause additional clean up. See pets section for dog guest guidelines.

Guest favourite
A spacious living area features dark hardwood floors and light gray walls, accented by a comfortable leather sofa and an elegant coffee table. Artwork adorns the walls, and natural light streams in from the nearby windows, illuminating the inviting space.
Apartment in Cape Girardeau
4.92 out of 5 average rating, 51 reviews

Downtown 4BR with 2 King Beds! Off-street parking

- Massive two story 2,400 sq ft historic apartment on Broadway - Recently renovated - Downtown location - Free off-street parking - Walking distance to SEMO and River Front - 2 King beds! - 3 Bathrooms - 2 futons and one couch for extra sleepers - Self check-in with smart lock - Full kitchen - Washer/Dryer included - Formal dining area - Second cozy living room upstairs - Room darkening shades in all bedrooms - Note: narrow staircase at entrance

Guest favourite
An open-concept living area features a spacious leather sectional couch, a round coffee table, and a dining area with sleek pendant lighting. Natural light pours in through large windows, highlighting the exposed brick walls and modern appliances in the kitchen.
Apartment in Cape Girardeau
4.84 out of 5 average rating, 69 reviews

Downtown Cape 2 Bdrm/2 Bath Apt | Cozy & Walkable

Experience style and convenience in this new, cozy, fully outfitted central apartment. Enjoy your privacy while being right in the heart of downtown Cape Girardeau! You’ll be seconds away from great restaurants, bars, shops, and more! A great stay for both short-term and mid-term stays! - King-size bed - Dedicated workspace + highspeed wifi - Fully equipped kitchen - Laundry machine in unit - Free parking - Walkable area, near trails and park

Guest favourite
Apartment in Cape Girardeau
5 out of 5 average rating, 15 reviews

Studio Apt | King Bed, Full Kitchen · By KeenStays

This bright and airy studio apartment offers a neutral, boho vibe with modern comforts. Relax in the king bed or fold it up into a day bed. Enjoy a fully equipped kitchen with an eat-in bar and unwind in the cozy seating. For added convenience, enjoy a full bathroom, in-unit laundry, and a dedicated workspace. Perfectly located in the heart of downtown Cape Girardeau, it’s the ideal spot for both relaxation and productivity.

Superhost
The living room features comfortable seating for four and a bay window providing natural light. A SmartTV is mounted on the wall, with a cozy fireplace ambiance displayed. Decorative plants and framed artwork enhance the welcoming environment, inviting relaxation.
Apartment in Cape Girardeau
4.8 out of 5 average rating, 5 reviews

Rivers Dawn- Historic Home - River View - King Bed

This cozy upstairs loft is just steps from Downtown Cape Girardeau, offering stunning views of the Mississippi River, Bill Emerson Memorial Bridge, and historic district homes. Enjoy peace and quiet, with the vibrancy of downtown just a short walk away. Perfect for those seeking a relaxing retreat with easy access to the area's best attractions. Ideal for both relaxation and exploration!

Guest favourite
The exterior of a two-story home is shown, featuring a combination of brick and siding. A covered porch is located at the front, and large windows are visible. Lush green grass surrounds the house, with trees providing shade and a peaceful atmosphere.
Apartment in Oak Ridge
4.86 out of 5 average rating, 28 reviews

The Teal Door

Relax with the whole family at this peaceful place to stay. All on one level, no steps. Property is 5 years old and very clean. Just 3 miles west of I-55 exit 111. Only 20 minutes from Cape, Jackson or Perryville but still has country charm. Places to dine within 10 minutes. Local cafe next door for quick lunch or dinner.

Superhost
An open living area features warm wood flooring and exposed beams. A comfortable couch and a small rug are positioned near a modern kitchen island, which is surrounded by black cabinetry. Natural light fills the space through large windows, enhancing the urban loft ambiance.
Apartment in Cape Girardeau
4.89 out of 5 average rating, 27 reviews

Downtown Loft 1 on Main

This urban style loft is centrally located in the heart of downtown Cape Girardeau. You will be doors away from fine dining, boutique shopping, and live music. This building was one of the original land marks of our river town. Make your reservations early to snag this location.

Popular amenities for Cape Girardeau apartment rentals

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Avg. price$204 NZD$186 NZD$189 NZD$209 NZD$216 NZD$216 NZD$217 NZD$216 NZD$199 NZD$196 NZD$204 NZD$181 NZD
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Quick stats about apartment rentals in Cape Girardeau

  • Total holiday rentals

    Explore 40 holiday rentals in Cape Girardeau

  • Nightly prices starting at

    Cape Girardeau holiday rentals start at $66 NZD per night before taxes and fees

  • Verified guest reviews

    Over 2,320 verified reviews to help you choose

  • Family-friendly holiday rentals

    20 properties offer extra space and kid-friendly amenities

  • Pet-friendly accommodation

    Find 10 rentals that welcome pets

  • Rentals with dedicated workspaces

    30 properties have a dedicated workspace

  • Wi-Fi availability

    40 of Cape Girardeau holiday rentals include Wi-Fi access

  • Popular amenities for guests

    Guests love Kitchen, Wi-Fi and Pool across Cape Girardeau rentals

  • 4.8 Average rating

    Cape Girardeau stays are highly rated by guests—averaging 4.8 out of 5!