
Apartment holiday rentals in Cape Girardeau
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Top-rated apartment rentals in Cape Girardeau
Guests agree: These apartments are highly rated for location, cleanliness and more.

Beautiful Historic Boulevard District Apartment
This beautiful, private upstairs apartment is located on a favorite street in Cape Girardeau’s Historic Boulevard District. It is walking distance to SEMO University, Capaha Park, and the downtown riverfront. Recently remodeled for laundry, spacious rooms offer private bedroom spaces and a cozy den for watching movies or reading. The kitchen is fully equipped with amenities. This quiet neighborhood setting even has a front porch swing and sitting area where you can enjoy your morning coffee.

Rivers Dusk- Historic Home - River View - King Bed
This charming 1900s home blends historic character with modern luxury. Original features like a green-tiled fireplace, marble hearth, glass French doors, 10-ft ceilings, large windows fill the space with light. Modern amenities include hand-scraped hardwood floors, a full kitchen with stainless appliances, custom cabinets with granite tops. Located in Historic Downtown Cape Girardeau, enjoy river views and easy access to local shops or relax in this grand home. Inquire for available discounts.

Brand new 2 bedroom unit right in downtown Cape.
This special place is close to everything, making it easy to plan your visit. Walking distance to restaurants, the river and nightlife. Property includes wifi, full kitchen, laundry, deck and private parking for one. One king bed room and a twin bed room in addition to a roll out twin bed along with a 60 inch smart television. Dog bed and bowls included along with board games! Property is conveniently located across the street from "The Bar" the famous spot from the movie "Gone Girl" .

Regal Rustic Retreat
Take it easy at this unique and tranquil getaway. Close to SIU Carbondale and also Murphysboro. We offer a quiet, simple apartment to relax and recharge. Free local over the air television. We have broadband/smart monitor for your HDMI stick . Bring your own Roku or Firestick with your subscriptions. The second bedroom is an open loft area, not a separate room. We offer a large storage space for bicycles and mudroom with washer/dryer for cleaning up after a hike or bike race. Full kitchen.

Historical Kage House
The Building is reminiscent of eighteenth-century New Orleans architecture, and was built sometime before 1883. The Kage House is located at 120 Broadway in the historical district and is less than a minutes walk to Main Street and less than a 10 minutes walk to the Isle of Capri Casino. On Main Street you will find many fine shops and restaurants, or just enjoy the scenic area as you walkabout. This is by far one of the best places in Cape. Additional reviews can be read on the VRBO website.

Unique Design | Walk Downtown/River | .5 mile SEMO
At our Adventurous 2 Bedroom Suite you’ll first arrive at a Brightly decorated Space with Artsy Walls and Bold Decor. Designed with its History in mind & a twist of Creativity, you will Immerse Yourself within your Stay; from our Stocked Kitchen, Reading Area with Indoor Swing to Themed & Cozy Bedrooms. Enjoy being near Downtown/the River with a short Bike Ride or Walk and when you are ready to Tuck in at night, Sink into our 10” Memory Foam mattress with Plush Pillows and feel at Ease.

Mayberry Retreat
This unique place has a style all its own. Come enjoy our 2 bed (king and queen), one bath vacation unit, where you can slow down and enjoy what’s close by : wine trail, hiking the little Grand Canyon, Giant City and other Shawnee National forest sites; fishing or floating the many lakes; shopping local for antiques or visiting the university. Major cities nearby- St Louis, Cape Girardeau, and Paducah KY. No pets. No smoking in the unit. Trains run past and nearby. Maximum 4 people stay:)

The Outlook - Private Balcony
Welcome to 115 N Water, Unit 103 in Cape Girardeau, MO! This delightful property not only offers a cozy retreat but also boasts a private balcony with stunning, unobstructed views of the Mighty Mississippi River. Perfectly situated close to downtown, it's just steps away from a vibrant nightlife scene, with numerous bars and restaurants for an unforgettable date night experience. Enjoy the best of both worlds – scenic beauty and lively entertainment – right at your doorstep!

Visit the "Gone Girl" neighborhood
Living rm/bedrm, full kitchen, ADA bath, and walk in closet. Fully equipped with dishes,linens, refig, micro,stove, keurig, dishwasher and welcome home snacks. Double Murphy bed, queen hide a bed couch convert the living room to bedroom. Space is good for up to 3 adults, 2 adults and 2 children or a single guest. We accept well mannered dogs up to 50 pounds. We do not accept CATS. Like cats but they cause additional clean up. See pets section for dog guest guidelines.

Luxe 2KBR Apt w/ Electric Fireplace · By KeenStays
This luxury apartment offers a unique blend of modern elegance and cultural charm, nestled right above the beautifully revitalized Broadway Theatre. Enjoy a vibrant stay by being in walking distance to shopping, dining, and downtown entertainment! The apartment features a spacious, light-filled layout with high-end finishes and appliances. Enjoy cozy living spaces complete with an electric fireplace. Don't forget to visit the bourbon lounge below and bistro next door!

Downtown 4BR with 2 King Beds! Off-street parking
- Massive two story 2,400 sq ft historic apartment on Broadway - Recently renovated - Downtown location - Free off-street parking - Walking distance to SEMO and River Front - 2 King beds! - 3 Bathrooms - 2 futons and one couch for extra sleepers - Self check-in with smart lock - Full kitchen - Washer/Dryer included - Formal dining area - Second cozy living room upstairs - Room darkening shades in all bedrooms - Note: narrow staircase at entrance

Urban-Chic King Suite Near SIU Carbondale
Stay at Suite 1, Wall Street Suites — an urban-chic king suite near SIU Carbondale. Once the city’s water department, this renovated space features stylish decor, full kitchen, Smart TV & modern bath. Guests enjoy shared lobby workspace & seating. Perfect for monthly or mid-term stays, it’s just steps from SIU East Campus — where historic character meets modern comfort in the heart of Carbondale.
Popular amenities for Cape Girardeau apartment rentals
Weekly apartment rentals

Fresh & Cozy Retreat w/ King Bed · By KeenStays

Cozy & Comfortable 1 Bedroom Suite

Location, Location, Location!

Captain Cook's Quarters

River Retreat Apt in Downtown Cape G

Emonyah blue bottom apartment

INN Keepers Quarters

Rivers Dawn- Historic Home - River View - King Bed
Private apartment rentals

Gail's Corner Window- River View

Private Nurse Retreat 2 + Walk to SEMO Activities!

Modern 2BR Apt w Electric Fireplace · By KeenStays

The Plum Door

Art Deco Downtown Loft 2BR 1BTH Apartment

Downtown Retreat

Modern Boho Getaway · 1BR Apartment · By KeenStays

Private Nurse Retreat 1 + Walk to SEMO Activities!
Family-friendly apartment rentals

2 Bed Room Downtown carbondale

Downtown Cape Getaway with River Views

DownTown Carbondale 2

Murphysboro Retreat w/ Deck Near Kinkaid Lake!

2Bdrm Stay in Downtown Cape | Walkable, Laundry

Extended stay DownTown Carbondale

Bloom House Downtown 2BR 1 BTH Oasis

Quiet lakeside retreat for 2!
When is the best time to visit Cape Girardeau?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | $214 NZD | $195 NZD | $198 NZD | $219 NZD | $226 NZD | $226 NZD | $228 NZD | $226 NZD | $208 NZD | $207 NZD | $217 NZD | $195 NZD |
| Avg. temp | 1°C | 4°C | 9°C | 14°C | 20°C | 25°C | 26°C | 25°C | 21°C | 15°C | 8°C | 3°C |
Quick stats about apartment rentals in Cape Girardeau

Total holiday rentals
Explore 30 holiday rentals in Cape Girardeau

Nightly prices starting at
Cape Girardeau holiday rentals start at $69 NZD per night before taxes and fees

Verified guest reviews
Over 2,350 verified reviews to help you choose

Family-friendly holiday rentals
20 properties offer extra space and kid-friendly amenities

Pet-friendly accommodation
Find 10 rentals that welcome pets

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wi-Fi availability
30 of Cape Girardeau holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Kitchen, Wi-Fi and Pool across Cape Girardeau rentals

4.9 Average rating
Cape Girardeau stays are highly rated by guests—averaging 4.9 out of 5!
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