
Pet-friendly holiday rentals in Cape Girardeau
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Top-rated pet-friendly home rentals in Cape Girardeau
Guests agree: These pet-friendly homes are highly rated for location, cleanliness and more.
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Popular amenities for Cape Girardeau pet-friendly home rentals
Pet-friendly house rentals

Twisted Sister's Retreat
We were in town for a girls get away with some hiking and Twisted Sister was perfect! Such a beautiful setting and so close to the places we wanted to go. It was super easy to get in, very clean, and had everything we needed to cook for ourselves as we prefer to do. We also enjoyed strawberries from Flamm Orchard, and great hikes at nearby Little Grand Canyon and Cove Hollow, plus of course Giant City State Park. Candace was an excellent hostess. She lives next door but gave us complete privacy. And when I had questions or wanted recommendations she was super responsive. It made us feel safe and cared for. It is so nice that she shares her beautiful property with guests in this way. We will be back!

Experience Carterville Charm near Southern IL Univ
Great place, recommend and would stay again

Sleeps 16! 7 Bedrooms! 8 Bathrooms! 8 Beds!
We had a group of 15 and this home was absolutely perfect for our stay! There’s a ton of gathering space, especially in the living room where the large couch and footrest easily accommodated everyone. The multiple dining areas upstairs also made mealtimes easy and comfortable. The kitchen was incredibly well-stocked — we cooked every meal for all 15 of us without any issues. Having the extra fridge downstairs was a huge plus for storing all our food and drinks. The outdoor area is truly picturesque. We loved lounging on the deck, soaking in the peaceful surroundings, and listening to the local wildlife. All of the bedrooms were spacious, and it was a huge bonus that everyone upstairs had their own bathroom. The home had everything we needed and more — highly recommend for large groups!

Cedar Lake Retreat
I went to SIUC many many years ago and never visited Giant City. We came down to visit the campus and Giant City and Theresa’s place allowed us to bring our pet and was a great location. It was clean and nicely decorated at a good price.

Owls Nest
My sisters and I came to Carbondale for our family reunion. We wanted to just be us because we all live in different states. I found Laura's home on this website and fell in love. Her home looked EXACTLY like the picture! It was a little far out but it was ABSOLUTELY perfect!! It's was so relaxing and peaceful. Laura was also a GREAT host! She checked on us to make sure we were ok and made herself available if we needed her. Did I mention she had snacks available for the kids!?!! That was so sweet of her to do that!! Her home was very clean and spacious. I would DEFINITELY recommend to anyone that plans to visit the area or to anyone that just needs a peaceful weekend getaway. You will NOT be disappointed!! I definitely plan to book this location again!!

Located near downtown and casino
Great house, great location. Quiet neighborhood. Beds were comfortable. Plenty of room for my son to play. He loved playing in the basement.

Shawnee Forest Vacation Lodge
Kevin’s place was PERFECT!! Super cozy & CLEAN! Our family loved the peaceful, secluded location. Kevin quickly responded any time I had a question and gave us several good recommendations. Our pups felt right at home too. We look forward to staying here again!

Cottage Near Casino
Had a great stay. Was there for work and it was a quick drive to everywhere in town. Quiet and peaceful just what was needed for my off hours.
Pet-friendly home rentals with a pool

Glamping W/Hotub, pool, & lake
Loved our time here and will definitely return!

Peaceful Custom Carbondale Home w/ Pool, Near SIU!
Loved staying at this location. So close to restaurants and shops and outdoor adventures. Very quiet. Amazing views of stars. Plenty of sleeping spaces. Very responsive and helpful host!

Pond/Pool/Fire pit/Pet Friendly
It was well worth the $! I had an amaziiiiing weekend! It’s absolutely beautiful- inside and out! The pool was SUCH a good time, I could’ve stayed in it for days! We grilled out and swam, it’s an unbelievably fun & peaceful experience. The host was extremely responsive, helpful and checked in making sure we had everything the whole stay. I would recommend it for sure! If I could give it 6 stars I would! I will definitely be staying here again!!!

Camp in quiet w/ Spa Lake Pool
We loved staying in Kevin's RV. The kids thought the bunk room was really cool. There were 2 adults, 3 kids and 1 infant and we had plenty of room. Everything was as listed and had everything we needed.

Wooded, Private Lake, Pool & Spa
We chose to take this trip for our daughters birthday weekend a perfect setting to get away and have the option to camp, fish, swim and able to relax around a peaceful fire while eating smores. The camper had everything we needed very nice and spacious. The beds were very comfy. The area was nice and quiet. We caught fish from the dock. The family was welcoming to the pool area. And cant forget the friendly Pugley. He was for sure a bonus he loves to play fetch.

Carbondale Pool House - Sauna, Hot Tub, Dogs OK
Our stay was amazing. Our host were super accommodating of some special requests we had. The pool house was just we needed to make our two night stay the most memorable for our family.

Black Bear Cabin K03A
It was very clean when we arrived and we really enjoyed our stay! The dogs loved it and it was very peaceful! we will be back!

Brick Estate with pool in Quiet Neighborhood
Dave’s place was perfect for our family. There were 5 of us and we had plenty of room. It’s an older home, but has been kept up very well, and is very charming. The neighborhood is beautiful and we loved taking walks every day with our kids. Dave was very communicative and responded immediately if we ever had a question. Thank you Dave, we hope to be back soon!
Private, pet-friendly home rentals

*Convenient | Downtown-River-Casino-SEMO-Hospital
Great stay that worked perfectly for our group's needs - amazing price and close to all the places we needed. Samantha was super responsive and accommodating!

4Bdrm~EACHw/PRIVATEBathrms!
Casey’s house is amazing! We had the windows open all weekend because of the weather, and it was so peaceful. Loved the surrounding trees and the comfy screened-in back porch. Casey was the perfect host and very accommodating with my requests. Would 100% stay there again!

Welcoming, Pet-Friendly Home in Carterville
We stayed here while in town for a family graduation and it was a perfect spot to rest in between celebrations. The space was clean and comfortable, and the host was quick to respond to any questions we had. Great experience overall. Thanks Amanda for being a great host.

Hutchins Creek Cabin -2br- Wine Trail & Wilderness
This was hands down the most favorable experience I’ve had with Airbnb. Not only were the location and amenities perfect, but Amanda is also an amazing host! Super flexible and responsive, very helpful and accommodating, even allowing an extension of my reservation on a moment’s notice. I will definitely be back. Thanks so much, Amanda!

[*Charming Cozy Suite*]
Exactly as described. The bed was amazing!! Very peaceful setting.

Premium Private Camping with Views and Swimming!
Beautiful open space on Connie’s property that is completely private. The field and campsite were very well maintained. The creek next to the campsite was my dog’s absolute favorite. Hosts are super friendly/helpful about check in & getting to the property. Would absolutely recommend to anyone who loves peace and quiet or looking to get outdoors.

Tiny House on the lake, also called cabin #4
Had a lovely stay! Feeding the turtles from the porch and canoeing around the pond were the highlight of our trip. We hiked the little grand canyon and visited Scratch Brewery during the day, perfect addition to a relaxing weekend surrounded by beautiful nature.

Private Getaway on 270 Acres w/ Lake: Swim & Canoe
AWESOME people and place, some of the amenities weren’t ready to use but as far as the cabin that you stay in and the owners were incredible! Great location if you’re doing anything in Advance. They went the extra mile to accommodate traveling duck hunters. Will definitely stay again when I’m in Advance!
Quick stats about holiday rentals that are pet-friendly in Cape Girardeau
Total rentals
40 properties
Nightly prices starting at
$66 NZD before taxes and fees
Total number of reviews
3.3K reviews
Family-friendly rentals
20 properties are a good fit for families
Rentals with dedicated workspaces
30 properties have a dedicated workspace
Wi-Fi availability
40 properties include access to Wi-Fi
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