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Holiday houses in Isola

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Top-rated holiday rentals in Isola

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
Villa in Syracuse
5.0 out of 5 average rating, 76 reviews

Timeless: Detached villa with infinity pool

In the heart of the Plemmirio Marine Protected Area, this 90-square-meter (969-square-foot) detached villa features an 80-square-meter (861-square-foot) heated infinity pool and offers breathtaking panoramic views of the Sicilian coast from Plemmirio to Capo Passero. The villa is surrounded by a private 8,000-square-meter park featuring an abundance of typical Sicilian vegetation (olive, carob, almond, and fig trees; Mediterranean pines; mulberry trees; and a rock garden with Mediterranean scrub).

Top Guest favourite
Home in Noto
4.96 out of 5 average rating, 54 reviews

Penthouse Lady Packard

Lady Packard’s Penthouse just had a glow up!✨ A stunningly elegant, spacious and comfortable house with four levels, all above ground because of the sloping, pedestrian street on which it is built. Free parking is just steps away. The location is ideal, peaceful with amazing views, and just a few minutes’ walk from the city's center. The house sleeps 6 adults in 3 separate bedrooms. Perfect for a family holiday or a friends getaway, the common spaces comfortably accommodate everyone at once.

Guest favourite
A clear pool reflects the sunlight, surrounded by a spacious garden with lush greenery. White lounge chairs are positioned along the water's edge, creating a serene environment for relaxation. Tall trees provide shade, enhancing the tranquil atmosphere of the outdoor space.
Home in Syracuse
4.94 out of 5 average rating, 36 reviews

Allisola Country Villa - casa Carrubo

Allìsola is an ancient Sicilian residence, nestled in the beautiful protected area of Plemmirio, a few kilometers from Syracuse. From a single body were obtained three refined houses, independent of each other, inserted in a single large outdoor space with green corners, terraces and a relaxing pool. There is a private terrace with outdoor furniture, a large garden with a swimming pool shared with guests of the property, and a parking lot surrounded by an olive grove

Top Guest favourite
A view from the balcony highlights vibrant flowers in white pots, overlooking a bustling square lined with historic buildings. The wide street is populated with pedestrians enjoying the surroundings under a clear blue sky.
Holiday home in Syracuse
4.97 out of 5 average rating, 159 reviews

Casa dei Leoni – Balcony Overlooking Piazza Duomo | Ortigia

Wake up overlooking Piazza Duomo in the heart of Ortigia. Casa dei Leoni, a real home in the very heart of Ortigia. Overlooking Piazza Minerva, just a few steps from the Cathedral, this elegant apartment blends the charm of Sicilian history with modern comfort. Bright interiors, a private balcony with an open view, and carefully curated spaces make Casa dei Leoni the ideal place for guests seeking beauty, peace, and an authentic stay in Syracuse’s historic center.

Top Guest favourite
The spacious sleeping area features a large white bed positioned against an arched stone wall. Soft lighting highlights the texture of the stones, while decorative elements add a touch of charm. A woven rug lies at the foot of the bed, contributing to the room's cozy appeal.
Home in Syracuse
4.94 out of 5 average rating, 190 reviews

Agàpe Ortigia

Agàpe Ortigia is an accommodation created with Love in the magical island of Ortigia, in the historic center, a stone's throw from the Duomo and the major sites of interest. The independent room is large and spacious, has a double bed, TV, free Wi-Fi, tea and coffee corner, but the peculiarity of this accommodation apart from the furnishings is the bathroom which, in addition to having the main amenities, offers a large sunken tub where you can relax.

Guest favourite
A view of the waterfront features a lush communal garden with palm trees and various plants. Comfortable green seating is arranged around a circular table, while serene waters stretch out in the background under a partially cloudy sky. Ships can be seen in the distance.
Loft in Syracuse
4.82 out of 5 average rating, 51 reviews

Sea view suite in Palazzo Blanco with terrace

Perfect for a couple looking for a romantic getaway on the beautiful island of Ortigia, in a noble palace just steps from the cathedral and all the local attractions. A luxurious and refined loft with sea views and a unique 120-square-meter terrace overlooking the sea inside Palazzo Blanco, a typical example of Syracuse Baroque architecture, where you can admire the beautiful sunsets while enjoying an aperitif.

Guest favourite
Apartment in Syracuse
5.0 out of 5 average rating, 11 reviews

Sky Rooftop Ortigia

In the vibrant heart of Ortigia, just a few steps from the touristic port, this charming home welcomes you in a truly unbeatable location. Here, you can immerse yourself in the authentic atmosphere of the historic center, surrounded by picturesque alleys, local shops, and traditional restaurants, with the sea always within sight. The apartment is located on the third floor and is accessible by stairs only.

Superhost
Apartment in Syracuse
4.75 out of 5 average rating, 4 reviews

Street 39 fine apartment 6

Welcome to Rua Riad, the perfect base to explore Ortigia. This elegant riad-style home blends Mediterranean charm with modern comforts and features a private pool for pure relaxation. Ideal for families or friends, it offers refined spaces and an intimate atmosphere surrounded by sea, culture, and timeless beauty. Note: due to stairs, it may not be suitable for small children or guests with mobility issues.

Superhost
Home in Siracusa (SR)
4.87 out of 5 average rating, 15 reviews

Casa Isola - Siracusa - beach 5 min walk

Welcome to Casa Isola! The house has been fully renovated in 2025 with the idea to create a peaceful space with loads of natural light, using neutral colours and earthy materials. It has a beautiful outdoor space to make the most of your stay in Sicily. We also spend our holidays in Casa Isola and we want you to feel at home as much as we do, so please enjoy it while taking good care of it!

Guest favourite
A private swimming pool is surrounded by a white deck and bordered by a low fence. Two lounge chairs are positioned by the pool, which reflects the clear blue sky and the lush greenery in the background, with a glimpse of the sea visible in the distance.
Villa in Syracuse
4.93 out of 5 average rating, 137 reviews

Biancapigna Holidays & Pool

Biancapigna Holidays is a charming cottage located in a quiet residential area very close to the Plemmirio cliffs where it is possible to admire breathtaking views. The house, all on one floor, has a floor area of ​​approximately 85 m2, plus verandas and outdoor spaces with a large garden, swimming pool area, barbecue area and laundry room. Free parking opposite the house

Top Guest favourite
Home in Plemmirio
4.98 out of 5 average rating, 114 reviews

Casa Francesca

Detached house directly located on the rocks in a private condominium context in the protected marine area of Plemmirio, in the seaside area of the beautiful city of Syracuse. Simply and tastefully furnished, with an unparalleled 360° view of the sea and a large terrace shaded by reeds where you can experience moments of relaxation and conviviality pieds dans l'eau.

Guest favourite
The spacious terrace is furnished with a wooden seating area, featuring a lounge chair and a table. Potted plants are placed around the area, and a light canopy provides shade. A peaceful view of the rooftops is visible against a soft evening sky.
Condo in Syracuse
4.92 out of 5 average rating, 100 reviews

Lovely apartment in the heart of Ortigia

In the heart of Giudecca, a stone's throw from the cathedral and the sea, on one of the most photographed streets of Ortigia. Elegant apartment, newly renovated, equipped with all the necessary amenities for your stay. Its strategic location on the island offers its guests an excellent central location but at the same time a quiet and peaceful stay.

Popular amenities for Isola holiday rentals