
Holiday houses in Isola
Find and book unique accommodation on Airbnb
Top-rated holiday rentals in Isola
Guests agree: these stays are highly rated for location, cleanliness and more.

Maisonette, 14 San Paolo
Maisonette San Paolo 14, an exceptionally elegant suite, is housed in a historic 17th-century building adjacent to the Temple of Apollo, following a meticulous renovation focused on comfort and design. As soon as you enter, you are enveloped by a positive energy that conveys serenity and harmony, making it the perfect place to relax. Equipped with a kitchen, an en-suite bedroom, and an elegant outdoor patio where you can enjoy unforgettable moments. The sense of intimacy that this residence conveys makes it ideal for couples and for the most discerning guests.

Allisola Country Villa - Ulivo house
Allìsola is an ancient Sicilian residence, immersed in the beautiful protected area of Plemmirio, a few kilometers from Syracuse. Three refined houses have been obtained from a single body, independent of each other, inserted in a single large outdoor space with green corners, terraces and a relaxing swimming pool. Guests have access to a private terrace with outdoor furniture, a large garden with a swimming pool shared with the property's guests, and a parking lot surrounded by an olive grove.

The Terrace over the Ancient Market of Ortigia
Charming home over the ancient market of Ortigia. This apartment offers a private terrace with stunning views of Ortigia and the sea. The modern and high-end design makes this accommodation unique. The Market is the most authentic place on the island of Ortigia, where the scents and flavors of yesteryear still find their perfect expression today. The apartment offers a bedroom with balcony and en-suite bathroom, a large living room with balcony, an open concept kitchen and an additional bathroom

OrtigiaTerraceSeaView-La Gorgone Ortigia Suites
Elegant suite with a sea-view terrace in the heart of Ortigia, the historic center of Syracuse. Located on the second floor of a historic building, the suite overlooks the island’s only remaining gate of Spanish origin. The true highlight of the property is the stunning private terrace with sea views. The location is perfect for exploring Ortigia on foot: the sea, historic landmarks, traditional restaurants, local markets, and Syracuse’s most beautiful squares are all just minutes away.

Island – for those who love nature, sea and culture
The house, surrounded by fields and with a beautiful view of the sea of Plemmirio, is located in a natural area of extraordinary beauty and tranquility. It is suitable and open to everyone NB: A car is essential. Upstairs, there is a small independent apartment belonging to other owners. Nearest sea: Scala Ruiz 350 m on foot. It is a place where you can forget about everything knowing, however, that if you want, in ten minutes you are in Syracuse, with its culture and worldly life.

The Loggia of Arethusa
La Loggia di Aretusa is a unique experience. You will experience your vacation within the myth of the nymph Arethusa and the Fountain named after her, stunned by the scent of the sea mixed with that of magnolia, enjoying the extraordinary view of the Port of Ortigia, the suggestion of the sunset, the calm of dawn, in a more than central unique location. You can sunbathe from your veranda, have breakfast or an aperitif with those you love and to whom you will give a unique experience.

Villa Lisa
Villa Lisa is a rare gem that preserves the authentic charm of 70s Sicilian style. This spacious seaside retreat sits directly on the Plemmirio Nature Reserve, a stunning marine protected area of Siracusa. Here, your days unfold in total relaxation — slip into your swimsuit at breakfast and spend hours swimming, sunbathing or snorkeling in the crystal-clear waters right at your doorstep. Villa Lisa offers not just a stay, but a truly immersive Sicilian coastal experience.

Timeless: Detached villa with infinity pool
Nel cuore dell'area marina protetta del Plemmirio, villa indipendente di 90mq con piscina a sfioro infinito di 80mq, riscaldata, che offre una vista panoramica mozzafiato sulla costa siciliana dal Plemmirio sino a Capo Passero. La villa è circondata in da un parco di proprietà di 8000 mq ricco di vegetazione tipica siciliana (ulivi, carrubbi, mandorli, pini mediterranei, alberi di gelso, alberi di fico, giardino roccioso con macchia mediterranea).

Cortile Crocefisso apartment
Our flats are located in the Jewish quarter of Ortigia,a few steps from Piazza Duomo and the sea. The apartment is equipped with every comfort, a complete kitchen, AC, SmartTV, WiFi, washer-dryer, safe. It consists of one living room with a sofa bed, a kitchen with a a laundry corner, 2 double bedrooms with their respective 2 private bathrooms and can accommodate groups/families of 4/6 pax.

Casa Isola - Siracusa - beach 5 min walk
Welcome to Casa Isola! The house has been fully renovated in 2025 with the idea to create a peaceful space with loads of natural light, using neutral colours and earthy materials. It has a beautiful outdoor space to make the most of your stay in Sicily. We also spend our holidays in Casa Isola and we want you to feel at home as much as we do, so please enjoy it while taking good care of it!

Biancapigna Holidays & Pool
Biancapigna Holidays is a charming cottage located in a quiet residential area very close to the Plemmirio cliffs where it is possible to admire breathtaking views. The house, all on one floor, has a floor area of approximately 85 m2, plus verandas and outdoor spaces with a large garden, swimming pool area, barbecue area and laundry room. Free parking opposite the house

Casa Francesca
Detached house directly located on the rocks in a private condominium context in the protected marine area of Plemmirio, in the seaside area of the beautiful city of Syracuse. Simply and tastefully furnished, with an unparalleled 360° view of the sea and a large terrace shaded by reeds where you can experience moments of relaxation and conviviality pieds dans l'eau.
Popular amenities for Isola holiday rentals
Other great holiday rentals in Isola

Ancient Greece House - Greek Theater

Villa Dicembre

5E Villa Charme- Sea View and Ortigia

Three Lemons House

Prestigious Villa with a private beach and 5 beds

Ronco Concordia

Syracuse Ortigia Circe sul Mare

Pool and Amazing Sea View at Plemmirio Reserve
Destinations to explore
- Fontane Bianche Beach
- Calamosche Beach
- Castello Ursino
- Teatro Massimo Bellini
- Villa Bellini
- Castello Maniace
- Etnaland
- Greek Theatre of Syracuse
- Castello di Donnafugata
- Oasi Del Gelsomineto
- Nature reserve of Vendicari
- Spiaggia Vendicari
- Sampieri Beach
- Fishmarket
- Isola delle Correnti
- Museo Emilio Greco
- Aci Trezza
- Temple of Apollo
- Necropolis of Pantalica
- Noto Antica
- Monastery of San Nicolò l'Arena
- Noto Cathedral
- Cavagrande del Cassibile Nature Reserve
- Museo Archeologico Regionale Paolo Orsi





