
Family-friendly holiday rentals in Little Italy
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals in Little Italy
Guests agree: These family-friendly homes are highly rated for location, cleanliness and more.

Sunny, Open 2 Story Apt Downtown w/ Parking
Our Spacious 2 Story, Beautifully Decorated Apt is the Perfect Home Away From Home for Families, Couples, Digital Nomad, or Solo Traveler Looking for a Comfortable & Convenient Place to Stay. Located in One of the Most Vibrant Neighborhoods in SD Little Italy is Known For its Restaurants, Cafes, & Local Shops. So Many Attractions! the Waterfront Park, CRSSD Festival, USS Midway Museum., Balboa Park, Petco Park, The Convention Center, Running/Bike Paths, The County Building. 1 Free Parking Spot

Admire Harbor Views from the Porch at a City Gem
Unwind in a cozy colorful casita in this light-filled 1920s Spanish bungalow decorated with Mexican folklorico. Take a walk into Little Italy for dinner. Or to a show at the Old Globe.What’s best, is how close you are to so much, all without needing a car. A very small single car garage is provided, think compact car. Street parking is free but challenging at times. The house is located directly below the incoming flight path. You are encouraged to read the reviews regarding this.Ideal for four.

San Diego at your doorstep
Relax with the family at this peaceful place to stay. Studio apartment furnished with queen bed and queen sofa sleeper enhanced w/ a fully enclosed outdoor living space which includes an outdoor kitchen, fireplace, washer and dryer. Child and dog friendly. Located in a quiet neighborhood a fifteen minute stroll from the SD Zoo, Balboa Park and Hillcrest. Close to public transportation. A fifteen minute drive to beaches, downtown SD, the airport, harbor, and little Italy. Free parking and WiFi.

Trendy Studio, Natural Light - Heart of Downtown
Large studio with comfortable queen sized Murphy Bed, a love seat, private entrance and private bath. Located in Cortez Hill - walk to the nicest neighborhoods in downtown like Little Italy, Gaslamp, East Village, and the Embarcadero. There is no full kitchen, but there is a small refrigerator, small microwave, and a pot for heating water. This is an ideal space for solo travelers, couples, events at the Convention Center, Padres Games, great eateries, and the best of Downtown San Diego.

Calm Luxury Penthouse Getaway With Panoramic Views
Welcome to the most relaxing and luxurious penthouse condo in Little Italy! Featuring 2 expansive balconies with sweeping views, my condo sleeps 4-6 comfortably and is situated right in the heart of San Diego's most desirable neighborhood, Little Italy. Enjoy an area that is rich in exquisite cuisine, boutiques, patio cafés, exciting bars and local breweries. Area amenities nearby feature the famous San Diego Zoo, beautiful Balboa Park, Waterfront Park, the Convention Center and much more!

Perfect Downtown Studio | Steps to Little Italy!
Conveniently located Downtown is this beautiful, light & airy studio apartment with everything you could need for a relaxing and comfortable stay. The studio features a free flowing design with a fully equipped kitchen, a beautiful queen bed, a workspace, a sparkling, modern bathroom and café style dining for two by the sunny window. Stay just steps to Little Italy with its mouth-watering restaurants, bakeries, piazzas & cafes or drive to San Diego’s best attractions just 10-15 mins away.

Gorgeous 2Bd Corner Bungalow in Little Italy
Little Italy Bungalows are located in the heart of San Diego’s most popular restaurant and entertainment district, Little Italy. Just one block from India Street, Farmer’s Market, and minutes from downtown, Balboa Park, airport, and harbor & beaches. This is a delightful neighborhood, steeped in local history and culture, and popular for dining and exploring. Little Italy Bungalows is perfect for couples, families, business travelers, convention-goers, single travelers and adventurers.

#1 LOCATION - Rare Luxury Home in Downtown
***THE BEST RATED RENTAL IN DOWNTOWN SAN DIEGO*** Location doesn't get better than this! Right in the heart of the lively Little Italy area in downtown San Diego. San Diego's best restaurants and nightlife in your backyard. Just blocks from the waterfront and a short Uber or walk to the Gaslamp, Convention Center & Zoo! All the frills: + Prime location! 98/100 Walker Score rating + Private parking + Private Sundeck & Backyard Stay at this modern luxury home for your next trip!

At Mine | Central Suite in the Gaslamp Quarter
This unit is a meticulously renovated historical hotel suite, designed by the renowned Italian firm Pininfarina, located in Downtown San Diego. Nestled in the vibrant Gaslamp Quarter, you'll find yourself in the midst of nightlife with an array of restaurants and bars in close proximity. The suite provides private and spacious accommodations catering to both vacationers and business travelers. Its features include a comfortable king-sized bed, a smart TV, central AC, and a mini-fridge

Spacious Studio in Little Italy with Parking
Ground level unit. Comes with parking in a gated/covered parking garage within the complex. Centrally located in Little Italy. Close to great restaurants and coffee shops and a private balcony for an awesome view for plane watching. Bird Rock Coffee Roasters is located in the apartment complex on the first floor (Kettner Blvd). The Crack Shack and Ballast Point Brewery are right across the street. The Main Street of Little Italy is 2 blocks away and Waterfront Park is about 3 blocks.

NEW Stylish❤️ of Downtown Little Italy w Parking/AC
Located in the heart of Little Italy San Diego, this street level condo has been completely remodeled and re-imagined to make your stay unforgettable. Designed with the eye toward comfort and entertainment. *AC w/ independent temp control in each room *Voice Controlled Sound System, 4K TVs in every room *Beautiful bathroom w/ dual showers *Walk to coffee, yoga & gyms, dining, entertainment, shopping! 6 min to Zoo 5 min Airport 9 min to SeaWorld 6 min Petco Park 8 min to Coronado

The Palms Villa Amazing Amenities Perfect Location
Professionally cleaned and sanitized every single time a guest checks out with higher cleaning standards than the ones set by local and federal authorities, using approved and working tested virus killing products. The perfect location right next to the Convention Center, Little Italy, Balboa Park and the Gas Lamp, within minutes of all beautiful San Diego attractions!! The most beautiful and relaxing experience with the best amenities perfectly balancing Zen and Luxury.
Popular amenities for Little Italy family-friendly rentals
Family-friendly home rentals with a hot tub

Colorful North Park Home | AC, BBQ, Private Office

Lionhead - Private Boutique Home

Mountain View Retreat in Gated Estate (Hot Tub)

Dragonfly Cottage - In the Heart of San Diego

Jacuzzi, Firepit, Sauna & Ice Bath, Rest & Relax

Barrio Logan Loft/ Detached Guest House

Beautiful Historic Home and Gardens Near Downtown!

Inviting Cozy Backyard w/Fire Pit Cabana & Hot Tub
Family- and pet-friendly home rentals

Modern Spanish Casita. Sunny & Quiet with Kitchen!

LOFT: Detached Cottage with Patio

Walk 2 Gaslamp & Petco; King bed, Parking/Patio!

Gated Parking | Panoramic Views | Walkable

Romantic Private Garden Studio Near Downtown

Fabulous 2 bed/2 bath, split-level downtown condo

Luxury Bay/Ocean view suite-San Diego/Mission Bay

Townhouse - Private Yard, La Mesa Village
Family-friendly home rentals with a pool

Lovely Guesthouse in garden setting

Hillcrest canyon home casita with pool access

Your Modern Lux Pool Resort in the Heart of SD

The BEST NEST Clean, peaceful, private, affordable

Private 1 BR Paradise retreat

Private Poolside Cabana

Custom Guesthouse, Balboa Park/Zoo/Hillcrest& pool

Mission Hills Charming suite, walkable to all.
Quick stats about holiday rentals that are family-friendly in Little Italy
Total rentals
180 properties
Nightly prices starting at
$156 NZD before taxes and fees
Total number of reviews
12K reviews
Pet-friendly rentals
60 properties allow pets
Rentals with a pool
40 properties have a pool
Rentals with dedicated workspaces
120 properties have a dedicated workspace
Destinations to explore
- Apartment rentals Little Italy
- Rentals with a patio Little Italy
- Fitness-friendly rentals Little Italy
- House rentals Little Italy
- Hotel rentals Little Italy
- Waterfront rentals Little Italy
- Rentals with a hot tub Little Italy
- Pet-friendly rentals Little Italy
- Rentals with an EV charger Little Italy
- Rentals with beach access Little Italy
- Rentals with a fire pit Little Italy
- Loft rentals Little Italy
- Condo rentals Little Italy
- Rentals with breakfast Little Italy
- Rentals with outdoor seating Little Italy
- Rentals with a beach view Little Italy
- Rentals with pools Little Italy
- Rentals with a fireplace Little Italy
- Rentals with a washing machine and dryer Little Italy
- Rentals with a sauna Little Italy
- Family-friendly rentals San Diego
- Family-friendly rentals San Diego County
- Family-friendly rentals California
- Family-friendly rentals United States
- Rosarito Beach
- Oceanside City Beach
- Torrey Pines State Beach
- Tijuana Beach
- Pacific Beach
- SeaWorld San Diego
- University of California San Diego
- LEGOLAND California
- Coronado Beach
- San Diego Zoo Safari Park
- Balboa Park
- La Misión Beach
- Oceanside Harbor
- Coronado Shores Beach
- Belmont Park
- Liberty Station
- Black's Beach
- Moonlight Beach
- Sesame Place San Diego
- Law Street Beach
- Torrey Pines Golf Course
- Mission Beach
- Santa Monica Beach
- USS Midway Museum