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Guesthouse holiday rentals in Mesa

Find and book unique guesthouse rentals on Airbnb

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Popular amenities for Mesa guesthouses

Family-Friendly guesthouses

Guest favourite
Guesthouse in Camelback East
4.86 out of 5 average rating, 558 reviews

Architectural Dream Guest House

JohnRating, 5 stars3 weeks ago
Great especially if you have transport great kitchen and patio wonderful design.... all the uber drivers were in awe of the architecture. good fir morning run just great
Guest favourite
Guesthouse in Camelback East
4.93 out of 5 average rating, 1,390 reviews

Centrally Located Renovated Guest House

KaylaRating, 5 stars6 days ago
Shaayna’s place was super clean which is something 100% important! Clean bathroom and tub/shower! Clean appliances! It’s located in a very peaceful area! Check in is pretty easy and WiFi is great! You’ll love it here!
Guest favourite
Guesthouse in Gilbert
4.95 out of 5 average rating, 310 reviews

Two Bedroom, clean guest house in Gilbert

CarolRating, 5 stars4 days ago
This was our second time to stay here. it is a comfortable and peaceful place to stay!
Top Guest favourite
Guesthouse in Ahwatukee Foothills
4.98 out of 5 average rating, 1,019 reviews

Boutique Hotel Style Guest House

RonRating, 5 stars4 days ago
The casita is a great place to stay! It’s very quiet and comfortable, well decorated and clean. I especially enjoyed the courtyard for morning coffee after walking on the nearby paths. Phil and Peggy are great hosts…very thoughtful and attentive to details. Loved the bottle of wine and chocolates!
Guest favourite
Guesthouse in Encanto
4.92 out of 5 average rating, 1,315 reviews

Coronado Private Casita (Private House)

ErikRating, 5 stars3 days ago
A nice little place to stay. The pool is well cared for.
Top Guest favourite
Guesthouse in Paradise Valley Village
4.96 out of 5 average rating, 163 reviews

Cozy Guest Home away from Home

JayRating, 5 stars2 weeks ago
The home was very clean and comfortable. Had no problems at all finding the place. Area was very quiet and private also. Would absolutely stay again if needed!
Top Guest favourite
Guesthouse in Paradise Valley
4.97 out of 5 average rating, 179 reviews

1BR Guest House with Private Yard

AudraRating, 5 stars2 weeks ago
We had a great stay! Quiet and loved the separate yard for our pup. Would highly recommend
Guest favourite
Guesthouse in Tempe
4.91 out of 5 average rating, 352 reviews

Unique urban habitat near ASU/downtown Tempe

TonyRating, 5 stars3 weeks ago
Great stay in Tempe. The bathroom was amazing—super clean and modern—and the natural lighting throughout the place made it feel bright and welcoming. AC was a little on the noisy side, but nothing that kept me from getting good sleep.

Guesthouses with a patio

Guest favourite
Guesthouse in Encanto
4.91 out of 5 average rating, 246 reviews

McDowell Suite

DonnaRating, 5 stars2 weeks ago
This great place was close to everything that i wanted to do, see and eat! Spotless, no clutter, cold A/C, and huge TV’s! Quiet area, parking spaces, and it had a washer and dryer! Comfy bed and pillows had me sleeping on a cloud every night! I definitely want to stay here again! Check in and out is easy and host is great with fast response.
Top Guest favourite
Guesthouse in Encanto
4.98 out of 5 average rating, 133 reviews

Private Guest House in Phoenix Arts District

NasirRating, 5 stars1 week ago
Nice and clean great location it felt very luxurious bed was firm and great on my back
Guest favourite
Guesthouse in Paradise Valley Village
4.92 out of 5 average rating, 126 reviews

Sunshine Studio! Phx/Scottsdale border!

MichaelRating, 5 stars1 week ago
Perfectly adequate little studio in Phoenix. If you plan on spending most of your days out and about it’s perfect. But if you like to stay in your rental and just enjoy the location I would drop a little more cash and get somewhere with more yard space and a pool.
Top Guest favourite
Guesthouse in Encanto
4.98 out of 5 average rating, 105 reviews

Spacious Midtown guesthouse with full privacy

MichelleRating, 5 stars5 days ago
Eric was super responsive and helpful in every way ! Would def return! Easy to get to downtown phoenix and we did Scottsdale one day super easy with uber!
Guest favourite
Guesthouse in Central City
4.92 out of 5 average rating, 148 reviews

Downtown Studio - Woodland Historic District

YaelRating, 5 stars5 days ago
The place is so cosy and nice, the price couldn’t be any better and you’re only 5 minutes away from downtown Phoenix!!
Top Guest favourite
Guesthouse in North Mountain
4.97 out of 5 average rating, 147 reviews

Zen Modern Casita w/ Private Pool + King Bed

GretchenRating, 5 stars3 weeks ago
Another great stay at Ann's casita!! Ann is an amazing host, her casita is wonderful! Highly recommended!
Top Guest favourite
Guesthouse in Camelback East
4.99 out of 5 average rating, 217 reviews

Your favorite PHX guesthouse!

RachelRating, 5 stars2 weeks ago
Bradley’s place was perfect! I really appreciated the thoughtful touches like the real plants, coffee station, and bathroom toiletries. It was peaceful, comfortable, and felt just like home. The private entrance with an enclosed gate was an added bonus and made the space feel extra safe. I will definitely stay here again when I return to Phoenix. I highly recommend!!!
Top Guest favourite
Guesthouse in Scottsdale
4.98 out of 5 average rating, 128 reviews

Entire Private Guest House with King Master

VeronicaRating, 5 stars1 month ago
I really enjoyed my stay!! I was in town for my son graduation and Camille's listing exceeded my expectations and will definitely recommend for anyone the area!! I would definitely stay again when I'm in town!!

Guest house rentals with a washing machine and dryer

Top Guest favourite
Guesthouse in Encanto
5 out of 5 average rating, 207 reviews

Adorable Willo Cottage in Historic Central Phoenix

JessicaRating, 5 stars4 days ago
Clean, stylish place close to downtown! So quiet and comfortable, but convenient to get everywhere. This is a wonderful getaway - everything you need!
Guest favourite
Guesthouse in Central City
4.97 out of 5 average rating, 244 reviews

NEW Stylishly Designed Casita Steps from DTPHX

ChristopherRating, 5 stars1 week ago
My extended stay (~11days) at this Casita was relaxing and quiet. Just the right size for a bachelor like me, or a couple traveling to Phoenix alone to visit some family or explore. The space is small, but not tiny. There’s plenty of room to spread out, but not enough to clutter. You will run into rental neighbors in the main house, mine all left me alone, and rarely used the communal outdoor spaces. I’ll definitely look at renting this Casita again if/when visiting the Phoenix area again.
Guest favourite
Guesthouse in Gilbert
4.97 out of 5 average rating, 104 reviews

Gilbert Guesthouse: Centrally Located Cozy Studio

ShayRating, 5 stars2 weeks ago
This is our third time staying here, and we love it! One of the best stays in Gilbert!
Top Guest favourite
Guesthouse in Camelback East
4.98 out of 5 average rating, 990 reviews

Private studio! Central to popular locations.

MollyRating, 5 stars5 days ago
This is a great place. Mike and Paige’s casita is decorated with many nice touches, it is super clean and comfortable with everything one needs.
Top Guest favourite
Guesthouse in Val Vista Lakes
4.94 out of 5 average rating, 279 reviews

Private Cozy Cottage in Gilbert. Close to it all!

HenryRating, 5 stars2 weeks ago
What a lovely cottage! So clean and so comfortable. This little cottage had absolutely everything we needed. We will definitely stay here again. And Marcy? So friendly and so responsive. She made us feel very welcome. One of the best airbnb's we have used.
Guest favourite
Guesthouse in Gilbert
4.85 out of 5 average rating, 255 reviews

Private and Quiet - 1 bdrm/1 bath Casita

ChristopherRating, 5 stars2 months ago
Nice neighborhood, quiet/private casita - perfect for my work trip!
Top Guest favourite
Guesthouse in Encanto
4.99 out of 5 average rating, 149 reviews

DARK HOUSE | private, modern Spanish casita

KyllaRating, 5 stars1 month ago
I have stayed at Donna’s listing more than a few times- it’s one of my favorite places to stay! Great location, value, amenities and extremely comfortable and organized. I can’t wait to stay again!
Superhost
Guesthouse in Tempe
4.91 out of 5 average rating, 137 reviews

Artist Studio Turned Colorful Casita in the Heart of Tempe

FinneganRating, 5 stars2 months ago
Really enjoyed my stay here! Some things were not entirely perfect — there was only one roll of TP, Ben was a little late with the check-in code, and the wifi was a little spotty — but the place itself was amazing; The sheets were clean and soft, the pillows were stuffed with soft, warm down, the wood furniture was beautiful and inviting, and there were coloring books that helped distract me from the pain of recovering from surgery. Whenever a train wasn’t passing through, the place was idyllic, and when there was one, the vibes ranged from soothing to ear-splitting (given, this was because I left the side door open & screened in at night). The neighborhood is beautiful, and there’s a park just down the way. I can’t recommend this place enough to someone looking for a peaceful, beautiful stay in Tempe.

Quick stats about guesthouse rentals in Mesa

  • Total rentals

    140 properties

  • Nightly prices starting at

    $50 NZD before taxes and fees

  • Total number of reviews

    11K reviews

  • Family-friendly rentals

    20 properties are a good fit for families

  • Pet-friendly rentals

    30 properties allow pets

  • Rentals with a pool

    50 properties have a pool

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