Guesthouse holiday rentals in Mesa
Find and book unique guesthouse rentals on Airbnb
Top-rated Guesthouses in Mesa
Guests agree: These guesthouses are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for Mesa guesthouses
Family-Friendly guesthouses
Guesthouse in Tempe
4.92 out of 5 average rating, 279 reviewsUnique urban habitat near ASU/downtown Tempe
8–15 Aug
Guesthouse in Gilbert
4.96 out of 5 average rating, 290 reviewsTwo Bedroom, clean guest house in Gilbert
27 May – 3 Jun
Guesthouse in Phoenix
4.8 out of 5 average rating, 413 reviewsThe Serenity Casita at the Sanctuary in Coronado
13–20 Jun
Guesthouse in Scottsdale
4.94 out of 5 average rating, 127 reviewsFarmhouse Cottage in the Desert
31 Aug – 7 Sep
Guesthouse in Phoenix
4.87 out of 5 average rating, 480 reviewsArchitectural Dream Guest House
20–27 Jan
Guesthouse in Phoenix
4.88 out of 5 average rating, 207 reviewsStellar Studio in Phoenix
28 Jan – 4 Feb
Guesthouse in Scottsdale
4.9 out of 5 average rating, 607 reviewsScottsdale guest suite
22–29 Aug
Guesthouse in Phoenix
4.96 out of 5 average rating, 143 reviewsCozy Guest Home away from Home
26 Jun – 3 Jul
Guesthouses with a patio
Guesthouse in Tempe
5.0 out of 5 average rating, 165 reviewsGuest house built in 2022 with everything you need
17–24 Dec
Guesthouse in Phoenix
4.99 out of 5 average rating, 119 reviewsM&M Phoenix Standalone guesthouse and pool
8–15 Jul
Guesthouse in Phoenix
4.98 out of 5 average rating, 131 reviewsYour favorite PHX guesthouse!
27 Aug – 3 Sep
Guesthouse in Phoenix
5.0 out of 5 average rating, 110 reviewsStylish Casita with Private Plunge Pool
8–15 Sep
Guesthouse in Phoenix
4.91 out of 5 average rating, 271 reviewsPrivate Guesthouse Near GCU University
24 Jun – 1 Jul
Guesthouse in Phoenix
4.92 out of 5 average rating, 155 reviewsGranada - Adorable, Chic Studio Apt Biltmore Area
29 May – 5 Jun
Guesthouse in Phoenix
4.98 out of 5 average rating, 128 reviewsPrivate Studio-Sized House in Historic Willo PHX
5–12 Sep
Guesthouse in Phoenix
4.96 out of 5 average rating, 141 reviewsSimple, Clean, Convenient Casita. Private, safe.
20–27 Dec
Guest house rentals with a washing machine and dryer
Guesthouse in Phoenix
4.95 out of 5 average rating, 912 reviewsStudio B industrial design
3–10 Nov
Guesthouse in Phoenix
4.9 out of 5 average rating, 210 reviewsEnchanting Ahwatukee Secret Casita
24–31 Aug
Guesthouse in Phoenix
4.98 out of 5 average rating, 813 reviewsPrivate studio! Central to popular locations.
30 Sep – 7 Oct
Guesthouse in Phoenix
4.99 out of 5 average rating, 170 reviewsAdorable Willo Cottage in Historic Central Phoenix
22–29 May
Guesthouse in Phoenix
4.98 out of 5 average rating, 124 reviewsBest Little Guesthouse in Melrose !
10–17 Aug
Guesthouse in Phoenix
4.93 out of 5 average rating, 262 reviewsBrand New Casita at South Mountain
3–10 Sep
Guesthouse in Phoenix
4.99 out of 5 average rating, 118 reviewsCASA OSCURA | private, modern spanish casita
18–25 May
Guesthouse in Phoenix
4.99 out of 5 average rating, 142 reviewsEncanto Cactus Flower Casita
12–19 Apr
Quick stats about guesthouse rentals in Mesa
Total rentals
120 properties
Rentals with a pool
40 properties have a pool
Pet-friendly rentals
20 properties allow pets
Family-friendly rentals
20 properties are a good fit for families
Total number of reviews
8.1K reviews
Nightly prices starting at
$67 NZD before taxes and fees
Destinations to explore
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