
Family-friendly holiday rentals in Mesilla
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals in Mesilla
Guests agree: These family-friendly homes are highly rated for location, cleanliness and more.

Quaint casita for 2
*Sep 2025 New bed/Aug 2024 New A/C mini split* Quiet cul-de-sac and peaceful landing spot within minutes to NMSU and Old Mesilla. Easy access to I-10 and I-25. Close to golf courses, shopping and the beauty of Las Cruces and Mesilla. Private entrance to casita, patio with dining table and a cozy bedroom, bathroom with tub/shower, WiFi, coffee station, refrigerator with small freezer, microwave. Wonderful hiking trails nearby and less than 60 minutes to White Sands National Park and ELP Airport.

Casita Conway 2
Step into your newly renovated one-bed, one-bath haven located at the heart of Mesilla Park. Enjoy a leisurely walk to Picacho Roasters for a delightful coffee experience, or hop on a cruiser bike for a charming ride to historic Mesilla. Immerse yourself in the local ambiance, sipping a drink to the backdrop of live music. As the morning sun rises, take a stroll amidst century-old trees that grace Conway Avenue. Welcome home to a blend of modern comfort and the timeless charm of Mesilla Park.

Old Mesilla Resort Style Condo
Enjoy this 2 bedroom, 2 bathroom condominium with resort amenities. The condo has all the features that will make you feel right at home. Whether you want to cook in the full kitchen, enjoy an evening by the fireplace, or catch some sun by the pool, you'll find all the comforts of home. The condo is located in a gated community, which offers access to a fitness center and pool. The condo is located in the heart of Old Mesilla, walking distance to restaurants, a coffee shop, and shopping.

Southwest Mexican Adobe Casa Historic District
This wonderful adobe home with refrigerated air is located directly in the heart of the city the Mesquite Historic District of Las Cruces. This Mexican home combines the neighborhood classic adobe style. Directly across the street is a Mexican cafe and a coffee shop. Seven minute walk to downtown which has wonderful pubs and restaurants. This home is located directly across the street from my other two casitas that are listed in Airbnb. Dog fee $10.00 which can be left on the table.

Airstream Airdream w hot tub!
Welcome to the “Retro Retreat,” a 1968 Land Yacht infused with NM’s enchantment. This vintage stay has been lovingly curated with elements of nostalgic Americana and contemporary desert chic, featuring vintage books, games, and iconic art. This fully restored tiny stay set amidst a pecan field in the Mesilla Park district offers modern amenities including a remodeled bathroom with shower, Wi-Fi, Smart TV, a mini-split for easy heating and cooling, and a private hot tub for relaxation.

Josefina's Queen Suite in Mesilla Plaza
Josefina's Queen Suite is located just off the Plaza in Historic Old Mesilla. Behind the thick adobe walls, you will find this tranquil retreat. Charmed by the ambiance of our historic Southwestern design and the Garden Greenhouse, our luxurious Queen Suite offers a cozy step back in time, weaving together old world charm and modern comforts like WIFI, mini fridge, Smart TV, AC, plush bathrobes and more. If the Queen suite is already booked, please check out our King Suite!

Getaway Guesthouse in Historic Mesilla
Welcome to our cozy guesthouse, just a few blocks away from the Historic Mesilla Plaza. You'll find unique shops, restaurants, bars, and art markets nearby, offering a delightful experience for all your senses! The mouth-watering scents of Chala's Wood Fired Grill and Spotted Dog Brewery will entice you, as they're just around the corner. You'll also hear the bells from one of the oldest churches in the area and enjoy live music from the neighborhood's restaurants and bars.

Cozy Casita w/private patio near Old Mesilla
This adorable casita is located just one mile from Historic Mesilla and 5 min from the interstate. The one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/air fry toaster oven/Keurig /double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), mini-split AC/ heater, and a private outdoor patio table and gas grill.

Yucca Casita in Historic Mesilla
Mesilla STR Permit #0830 We have created a sustainable design, including rainwater harvesting and water saving landscaping, solar energy, energy saving and efficient construction, electric vehicle charger (which is solar powered), composting, organic gardens, firepit, and labyrinth.This is the 3rd unit (Yucca Casita) that we've completed, the 1st being our home and 2nd our other vacation rental property - Ocotillo Casita.

Cozy Casita De Mesilla
Cozy casita just steps from Old Mesilla’s historic plaza and coffee shops. Unwind in your private courtyard with a hot tub, or curl up by the fireplace inside the guesthouse. A kitchenette adds comfort for longer stays. Mesilla Bosque State Park by the Rio Grande is only 4 minutes by car—or a short bike ride—perfect for birdwatching, sunsets, and peaceful walks. The ideal spot for a romantic getaway or quiet retreat.

2 bed, yard, pet friendly in Historic Mesilla.
Welcome to Casa de Sapo Verde! Nestled just outside the center of the historic Mesilla Plaza and on the edge of the area’s farmland, this cozy casita is the best of both worlds. Stay in this authentic Adobe home with vigas, coved ceilings, and brick floors and experience all Mesilla has to offer. Restaurants, galleries, and shops are all nearby, or you can stroll the ditch banks by neighboring farms.

Cozy Casita with Patio
Cozy casita (guest house) with patio in nice quiet neighborhood close to NMSU, Convention center, Memorial Hospital, Mountain View Hospital, Old Mesilla, ,wine country, shopping, convenient to White Sands, hiking, etc. Casita has private entrance, private bath, small refrigerator, TV, coffee maker, microwave, and wifi
Popular amenities for Mesilla family-friendly rentals
Family-friendly home rentals with a hot tub

Modern Hidden Gem- HOT TUB & Organ Mtn Views/Patio

Hidden Las Cruces Retreat

Private Oasis Near Old Mesilla with Pool/Jacuzzi!

Hot Tub Getaway

Cozy downtown adobe home with hot tub and sauna

Home in Las Cruces Casa de Flores Near NMSU

Pecan Palace w/ Game Room & HOT TUB (Near NMSU)

Casa de Vacaciones
Family- and pet-friendly home rentals

"Casa de MaĂz" centrally located - close to NMSU

Artistic Escape

Casa Elena Adobe casita in historic Mesilla

Mexican Adobe Casita in Historic District

New Modern/Cozy Spacious Home

NMSU Casitas “C" Pet Friendly!

Rubivista Casita

Casa La Jolla
Family-friendly home rentals with a pool

LUXURy, Heated POOl, Sunset Views, Early Check-in

Nature Retreat 12-min from Downtown (with pool)

Pet Friendly Luxury Retreat W/ Heated Pool & Spa

Cozy Casita Blanca at Hacienda de Las Cruces

Sancho's Condo De Mesilla

Year-Around Heated Pool | Desert Views | Pets Ok

Desert Oasis with Pool

Desert Peaks Casita
When is the best time to visit Mesilla?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | $227Â NZD | $222Â NZD | $222Â NZD | $206Â NZD | $222Â NZD | $222Â NZD | $204Â NZD | $207Â NZD | $184Â NZD | $222Â NZD | $222Â NZD | $222Â NZD |
| Avg. temp | 4°C | 7°C | 10°C | 14°C | 19°C | 25°C | 27°C | 25°C | 22°C | 15°C | 9°C | 4°C |
Quick stats about holiday rentals that are family-friendly in Mesilla

Total holiday rentals
Explore 40 holiday rentals in Mesilla

Nightly prices starting at
Mesilla holiday rentals start at $142Â NZD per night before taxes and fees

Verified guest reviews
Over 2,520 verified reviews to help you choose

Pet-friendly accommodation
Find 20 rentals that welcome pets

Holiday rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wi-Fi availability
40 of Mesilla holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Kitchen, Wi-Fi and Pool across Mesilla rentals

4.9 Average rating
Mesilla stays are highly rated by guests—averaging 4.9 out of 5!
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