
Guesthouse holiday rentals in Mission Bay, San Diego
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Top-rated Guesthouses in Mission Bay, San Diego
Guests agree: These guesthouses are highly rated for location, cleanliness and more.
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Popular amenities for Mission Bay, San Diego guesthouses
Family-Friendly guesthouses

Lovely Guesthouse in garden setting
We are so grateful to have been able to stay at Gwynn's place, it is so peaceful and lovely. Like a secret garden getaway. We loved all the small touches, and beauty of the space. Gwynn made us feel very welcome and comfortable! The pool is amazing and the outdoor spaces are delightful. Can't wait to stay here again.

San Diego Shangri-La
I really enjoyed staying here. It's on a canyon, which provided a great view and a nice breeze and was very quiet. We had our little dog with us and he loved being able to explore the yard. It's a great location in La Jolla / North PB. It's at the top of my list for my next trip to San Diego.
Charming Seashell Cottage Overlooking Garden
So eloquently and thoughtfully appointed in terms of design. So quiet and peaceful, and exceptionally clean. All of your potential needs are thought of.

Spacious, private Mt. Helix country style studio
Absolutely worth it. Beautiful place. Cozy with gorgeous gardens. Also a nice welcome touch of bowl of fruits, chocolates and plenty to drink. Loved it.

New Guest House - North Park
Lynae’s place was wonderful, as was Lynae! Balboa park right nearby, with gorgeous trails and scenery. Walkable to North Park area which had a fun variety of bars, shops, and restaurants. Lynae was a wonderful host - responsive, kind, flexible - and the home was bright, airy, with gorgeous views. We couldn’t say enough good things about the wall of jasmine walking in. Thank you Lynae for having us in your home!

Fletcher Hills - modern 1 BR.Easy, no step access.
This air bnb was the best place we could have stayed in San Diego. It had everything we needed and there were so many thoughtful touches. All I wanted was a Southern California beach vacation and Kristen had all of the gear we needed for that. We went to several beaches during our stay and it was about a 30 minute drive to every beach we went after waiting out morning rush hour traffic. Her backyard was my favorite part of our trip as we love watching sunrises and sunsets and it was so peaceful with great views. There is a lot of natural light in the air bnb as I didn’t understand initially there are solar tube lights throughout the unit which I thought were really cool. The air bnb is in a safe and quiet neighborhood and is a convenient location. The bed itself was very comfortable and we enjoyed being able to cook meals with a full kitchen and be able to do laundry. I would definitely will return when back in San Diego.

OB studio, ocean views, hot tub & garage parking!
Amazing stay at La casita !! Scott was an amazing host , had a binder of stuff to do locally and super attentive ! Will definitely be staying at La casita soon again

Law Street Retreat
Great, central location with everything we needed for a leaping off spot. Thanks!
Guesthouses with a patio

Adorable cottage in Talmadge
The place was exactly as described. It was clean, peaceful and private. Their landscape was beautiful with all of the different flowers. Carlos was great with communication and a pleasure to interact with. He made things as simple and straightforward as possible. We would definitely stay at his lovely place again.

Free Bikes. 5 min walk to Windensea Beach La Jolla
We had a great stay at Carolina's property. The property looks exactly like the pictures (really cute and bright) and any amenity that you might need was provided. Carolina is quick to communicate and very helpful. We will definitely return!

Private 1 BR Paradise retreat
Comfortable, cozy apartment with everything you could possibly need. Lovely setting that was very quiet. We were in town visiting family and did not have time to enjoy the pool and patio much but really appreciated the amenities. John and Jeanne were the best hosts we have ever had a AirBnB! Thank you both for such a great stay!

Downtown Cottage Minutes to Gaslamp & Petco Park
Great place to stay if you’re in town by yourself. Walkable to the convention center ~20 mins. Easy to get in and out of and quiet at night.

SDSU Central Cozy Casita | Fast Wi-Fi | Walkable
This little house was so cute! it was no problem to find, street parking was easy, it's close to SDSU, check in instructions were very clear. One thing to know is that the bedroom of the casita is directly next to the main house's patio, and sound travels.

Charming Casita with City and Bay Views
Our hosts were extremely gracious, helpful and available. The casita was as advertised (clean and charming). The yard full of plants was very serene and charming. We would definitely stay here again!

Cozy, Quiet and Private Backyard Studio Escape
I had an absolutely wonderful stay at Stephanie's place! The space was spotless and made me feel right at home. The location was fantastic and the check-in process was incredibly easy. Stephanie was an outstanding host, always quick to respond to any questions. I especially loved the rain shower! I highly recommend this Airbnb to anyone visiting San Diego and would definitely love to stay here again!

New (2022) North Park Abode w/ Roof Deck
A fantastic location in North Park near Balboa Park with gorgeous views from the 2nd floor deck. It made for a gorgeous backdrop for graduation family photos! There are ample nearby restaurant choices for this safe and quiet neighborhood. Comes with a very comfortable bed, and a variety of pillows with an efficient kitchenette.. only wish the shower head streamed more water. Hosts were very gracious and responsive to our requests. I definitly plan to stay here again and have already recommended this awesome place to friends.
Guest house rentals with a washing machine and dryer

Private beach guesthouse w/ private parking
This was my second time staying here and it was—once again—perfect! The location is amazing, the size is wonderful, and I loved all of the amenities.

Beautiful Private Villa walk to beach
We loved staying at Kim’s villa, we were comfortable and very much at home. We slept well and loved the surroundings. Thank you Kim, will definitely be back!

Carrie’s North Park Casita, in Heart of San Diego
Carrie's Casita was perfect for the two of us. A private little courtyard with lemon and orange trees and the scent of jasmine was very welcoming! The studio-style space was very comfortable and well-appointed. We took advantage of the outdoor seating for downtime after busy mornings of sightseeing. The walkable neighborhood has many architecturally interesting, historic homes with amazing front gardens filled with succulents and cacti of all shapes and sizes. The location is great for accessing great restaurants and boutiques. We would love to visit again!

Bay Ho Cottage w/ Ocean & Bay Views and Roof-Deck
Shane is a very helpful and responsive host! The condo is wonderfully clean and nicely furnished. The rooftop and back patio areas are private and great for eating outdoors. The condo and neighborhood are super quiet - the location is easy to get to. Parking is on the street next to the condo and we could always find a spot. We would definitely stay here again!

Sea Star Cottage
This place was super cute and a good location. Unfortunately, we had hot water issues. However, Jeff was quick to respond and check it out. He also, offered us a refund since the water couldn't be fixed during our stay and we chose to leave early. We highly recommend Jeff as a host and this cute cottage

Point Loma Private Apartment
The stay was amazing! Very safe and quiet neighborhood, parking was easy, unit was perfectly clean and roomy enough for the 2 of us. We stayed for a week so it was nice to have laundry and a full kitchen available. Check in was easy and all necessary information was provided before check-in so we never even had to contact the hosts!

Clean Cozy Private Guesthouse - Central San Diego
This airbnb was very nice for two people. It was a perfect space with a spot on the driveway for one car. Walking in, the airbnb was clean and smelled really good. There was plenty of amenities and our host Frank was friendly and responsive. We would book again!

Point Loma Oasis - Blocks From Sunset Cliffs
Great location, moments away from Sunset Cliffs and Ocean Beach. The unit was exceptional and easy to find . We were only there for one evening but it was peaceful and quiet and the entire area is beautiful. The communication from the host was on point . Highly recommend
Quick stats about guesthouse rentals in Mission Bay, San Diego
Total rentals
20 properties
Nightly prices starting at
$201 NZD before taxes and fees
Total number of reviews
2.8K reviews
Rentals with dedicated workspaces
10 properties have a dedicated workspace
Wi-Fi availability
20 properties include access to Wi-Fi
Popular amenities
Kitchen, Wi-Fi and Pool
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