Boutique hotel holiday rentals in Panama

Find and book unique boutique hotel rentals on Airbnb

Top-Rated Boutique Hotels in Panama

Guests agree: These boutique hotel rentals are highly rated for location, cleanliness and more.

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Superhost

Hotel room in Panamá

4.86 out of 5 average rating, 7 reviews

Avani Eco Hotel ~ Romantic Nature Getaway ~ Patio!

Step into the comfort of this beautiful queen suite in the high-end, eco-friendly Avani Boutique Hotel, offering easy access to sandy beaches and the many stunning amenities and activities of Contadora Island. Spend the day exploring this breathtaking island and then retreat to the attractive suite whose stylish design and scenic surroundings will mesmerize you. ✔ Comfy Queen Bed ✔ Spa-Like Bathroom ✔ Private Patio ✔ Wi-Fi ✔ Hotel Amenities (Breakfast, Transport, Activities) Learn more below!

Superhost

Hotel room in Boquete

4.89 out of 5 average rating, 111 reviews

Villa Alejandro - Tastefully Furnished Room

Just 5 minutes walk to centre, calmly situated and close to town located in an extraordinary mansion. Lovely furnished bedroom (King-Size/Orthopedic mattress) with private bathroom and walk-in closet . Affectionately decorated living room with spectacular view to the Boquete valley by large windows and large, full equipped kitchen can be shared with other guests. Lot of space for dining/reading in the living room. Lovely garden and terrace can be used. Gated carport. Fast WiFi, CableTV, Netflix

Guest favourite

Hotel room in PA

4.9 out of 5 average rating, 29 reviews

Treetop views of the Pacific in a boutique cabaña

No detail left unnoticed…our boutique cabañas are nestled in jungle gardens with private porches overlooking the Pacific, hammocks for lounging, indoor/outdoor concept bathrooms, stunning hardwood floors, and custom-made furniture. Each of our three cabañas has its own unique charm where comfort meets luxury. We are steps from the beach and minutes from consistent surf breaks and community yoga classes. A shared kitchen is on site, with individual cooking utensils provided for each room.

Guest favourite

Hotel room in PA

4.91 out of 5 average rating, 34 reviews

Villa Coco King Room

Villa Coco is a beautiful boutique hotel in Santa Catalina, only footsteps away of the world known surf break “La Punta” and Unesco world heritage Coiba island. The carefully designed cabañas, provide a space of tranquility and a sense of timelessness. Unwind in the hammocks and canvas chairs on your private terrace, dwell on reading your favorite book or sip on a cool drink from the bar. Our Restaurant “Ai Mamita” offers different kinds of meat, fresh seafood and other tasty delights.

Top Guest favourite

Hotel room in Bastimentos Island

4.95 out of 5 average rating, 64 reviews

Casa Florecer- bungalow at the edge of the sea

Welcome to Casa Florecer, a bungalow at the edge of the sea. Your space is simple and elegant. A studio apartment with plenty of room to enjoy a quiet & peaceful time on the island. The bungalow boasts a screened in porch, gorgeous views, and pristine coral reef for your front yard. All stays include a locally sourced vegetarian breakfast served in our over the water eatery, Juntos. For fun closer to home: we have snorkel gear, paddle boards, and yoga mats available for your enjoyment.

Superhost

Hotel room in Playa Venao

4.75 out of 5 average rating, 4 reviews

Ocean View Private King Bed Room @ Villa Marina

Amamos el océano tanto como tú. Por eso hemos creado el lugar perfecto para que disfrutes de las olas y de todo lo que el Pacífico panameño tiene para ti en las playas de Pedasí. Villa Marina Lodge es un lugar único en su categoría. Ubicado en Playa Venao, un paraíso internacional del surf, ofrece habitaciones cómodas y amenidades de primera para que tu viaje a la playa sea siempre una experiencia especial. Un lodge, a diferencia de un resort, es más relajado, casual y acogedor.

Superhost

Hotel room in Playa Venao

5 out of 5 average rating, 7 reviews

Olas Room - Quiet, Second Floor w/ Queen bed

Olas Room is a peaceful, economical, 2 person room located at the stunning El Sitio Hotel. Here you will find a comfortable clean, queen bed, a mini fridge in your room to keep your drinks cool and a bathroom equipped with hot and cold water to wash away the sand and salt after a day in the sun. Your room is steps away from an incredible pool/lounge area with a stunning view of the ocean. *A 10% tax will be collected separately as Airbnb do not collect tax on behalf of host.

Hotel room in San Carlos

4.77 out of 5 average rating, 127 reviews

B) Beach, surf and Relax with King size bed

Manglar Lodge is a small beach Hotel located at El Palmar beach on the Pacific coast on the town of San Carlos, If you like nature and comfort, you'll enjoy your stay at Manglar Lodge We are small beach hotel that offers the visitor four cozy and clean rooms, WiFi, restaurant (open form 8.30am until 9pm) with great food and a great selection of craft beer and live music on some weekends from 7pm to 9.30pm The Room is on a 1 floor you have to walk up the stairs

Superhost

Hotel room in Cambutal

5 out of 5 average rating, 11 reviews

Boutique Inn_The Hill 1_Private Entry_Sea View_16+

The Hill Panama, our Boutique Inn Adult Only (16+) is proud to be featured on Architectural Digest Magazine, located in the heart of enchanted Cambutal Beach, just a 5 five-minute walk to the beach, surrounded by several surf spots, balance between mountain and sea, hidden amongst the jungle canopy. This listed Room 1 was designed as a boutique hotel room with stunning ocean view from private deck, separated private entry and communal kitchen on side.

Guest favourite

Hotel room in Panamá

4.88 out of 5 average rating, 42 reviews

Habitaciones privadas Sofia's B&B Hostal Boutique

Alojamiento tipo hostal boutique, contamos con 7 cómodas habitaciones privadas con baño, para una capacidad total de 18 huéspedes. La tarifa mostrada por Airbnb para tu reserva distribuye 2 huéspedes por habitación, es decir, los huéspedes deberan compartir camas y/o habitaciones. Si requieres una distribución especial de habitaciones para tu grupo, contacta primero con el anfitrión, ya que la tarifa podría variar.

Guest favourite

Hotel room in El Valle de Antón

4.77 out of 5 average rating, 26 reviews

Suite medievale natura & arte

La Corte del Re é un hotel boutique composto da un insieme di suite con tematica medievale (arte macabra) immerse nel bosco dove arte e natura si fondono nel cuore del Valle di Anton. A pochi passi dal centro sono dotate di tutti i confort e contano con un parco, piscina, lago con carpe Koi e parcheggio. Sono suite e pertanto non dispongono di una cucina.

Guest favourite

Hotel room in Las Tablas Abajo

4.83 out of 5 average rating, 80 reviews

Blue Room for 2 at Casa Lassini - Oceanfront!

Blue Room - possibly our best room but you can decide. Queen bed, sleeps 2 and comes with everything you need to enjoy yourselves at the beach. A spectacular view overlooking the Pacific Ocean. Room is upstairs; includes A/C, smart TV, Netflix, full size refrigerator, microwave, toaster, coffee & coffeemaker.