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Guesthouse holiday rentals in Rancho San Diego

Find and book unique guesthouse rentals on Airbnb

Top-rated Guesthouses in Rancho San Diego

Guests agree: These guesthouses are highly rated for location, cleanliness and more.

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Guest favourite
A scenic view captures lush hillsides and a calm lake under a clear sky, with a rainbow arching gracefully over the landscape. Green vegetation sprawls across the area, adding vibrancy to the tranquil scene.
Guesthouse in Escondido
4.91 out of 5 average rating, 818 reviews

Hilltop cabin retreat with lake & mountain views

Rustic hilltop cabin overlooking Lake Hodges. Surrounded by open canyons & mountains, you will feel like you're a million miles away from everything as you take in the views from the cabin, deck or the outside shower, swim in the saltwater pool, or relax by the fire bowl. A short walk to lake with boating, fishing & miles of hiking/mountain biking trails. Property offers swimming pool, fire bowl, and shaded arbor. SD Zoo Safari Park, wineries, breweries, & ocean beaches all within easy reach.

Top Guest favourite
Two red Adirondack chairs are positioned under a covered patio, facing a serene backyard with a pool. Lush greenery surrounds the area, creating a tranquil atmosphere. A BBQ room and various seating arrangements are visible beyond the pool, enhancing the outdoor retreat experience.
Guesthouse in La Mesa
4.99 out of 5 average rating, 143 reviews

Private 1 BR Paradise retreat

Private, yet central. It is your exclusive paradise retreat to enjoy from your spacious 1 bedroom guest house located on the lower level of our home. Hang out in the expansive and private backyard with pool, different sitting areas and covered BBQ room. Or maybe a workout in the gym. Centrally located in the Village of La mesa. Just a 1/4 mile jaunt into the quaint village with its numerous assortments of dining options, stores and trolley station. Freeway close to beaches, downtown and airport

Top Guest favourite
An open layout studio is presented, featuring a cozy seating area with a grey couch and a rustic wooden coffee table. A dining space with a round table and chairs is visible. The kitchen area, equipped with modern appliances, is complemented by a ceiling fan with decorative light fixtures.
Guesthouse in La Mesa
5 out of 5 average rating, 105 reviews

NEW construction - Studio near the Village

New studio - Attached Dwelling Unit (ADU) with a private entrance. Walking distance to the Village of La Mesa which has several restaurants, shops and a Vons. Very close to SDSU and quick access to multiple freeways that take you to beaches, mountains, SD Zoo, the nightlife in downtown SD (8, 94, 125). Access to shared laundry room, 2 parking spaces and its own outdoor area. AC & heat. WiFi. Netflix, Hulu with live TV, Apple TV, Disney +, Prime Video and HBO Max. Crib and high chair upon request

Top Guest favourite
A welcoming entrance features a textured walkway leading to a front door, framed by a wooden railing. Colorful flowers bloom along the sloped landscape, enhancing the natural appeal of the surroundings. Clear skies and distant homes provide a serene backdrop.
Guesthouse in El Cajon
4.99 out of 5 average rating, 207 reviews

Modern mountain guest house. Incredible views

Neighboring San Diego, quaint country living with incredible views minutes from everything, breathtaking sunsets, 20 mins to beach, close by hiking trails, and only 3 minutes hop on the freeway. Full Kitchen, Laundry, and Living area and with beautiful furnishings, a perfect home away from home. Whether traveling for work or play we have had guests stay for a conference in San Diego or just to visit friends and hit the beach a few days, we look forward to you loving our home as much as we do.

Top Guest favourite
A private deck is shown, featuring a red umbrella over a round table with four chairs. The entrance to the guest house is framed by glass doors and accompanied by a vibrant red door. Lush greenery and flowerbeds enhance the outdoor space.
Guesthouse in La Mesa
4.99 out of 5 average rating, 208 reviews

Stunning Guest House 15 min. from Zoo, Downtown

Stunning guest house that's 15 minutes to San Diego Zoo + downtown San Diego. The cottage is decorated with mid-century and one-of-a kind furniture in a comfy living space overlooking a gorgeous garden. Enjoy the the garden on your private deck, watch TV while relaxing in the handcrafted Nicaraguan rocker or 1950s Danish slipper chair. The cottage also has a comfy queen-sized bed and a full kitchen that's stocked with what you'd need. Oh, and all guests arrive to a homemade loaf of bread.

Guest favourite
A compact kitchen area features a marble countertop with a gas stove, dual wooden stools, and a modern sink. Natural light streams in through the window, illuminating the clean lines of the cabinetry and the adjacent cozy sleeping space.
Guesthouse in City Heights
4.83 out of 5 average rating, 211 reviews

Sunny and Affordable Studio W/private outdoor yard

This a great home base to explore San Diego ! It’s a small studio ideal for a one person or couple to get some rest after enjoying San Diego all day. 1 mile to Northpark restaurants/bars/breweries 10-15 mins to Gaslamp,Old town, Seaworld Ocean beach. Full kitchen , coffee corner , gas stove and comfy full size bed. Private entrance from alley. STEET PARKING ONLY - will be very hard to find at night. Used to be a garage decades ago

Top Guest favourite
A cozy interior features wooden paneling and a comfortable grey sofa with a decorative pillow. A small kitchenette is equipped with cabinets and appliances. A dining table is set for two, and a guitar is displayed on the wall, adding a touch of creativity to the space.
Guesthouse in La Mesa
4.92 out of 5 average rating, 206 reviews

La Cabana

Perfect getaway for the wandering individual, couple, or young family. This rustic casita is surrounded by beautiful mountain and ocean views! Enjoy swimming in the pool, stargazing, lounging, or casual day trips around San Diego (All the amenities are shared with the main house) . The casita has one queen bed and a sofa bed, small kitchenette. Plenty of parking in driveway. Please read entire listing for details.

Top Guest favourite
The exterior of a two-story building is surrounded by lush tropical plants, including tall palms and vibrant greenery. A paved walkway leads to a private entrance, which is framed by a low wall and several ornamental plants, creating an inviting and serene environment.
Guesthouse in Chula Vista
4.95 out of 5 average rating, 607 reviews

Private Casita in Great Eastlake Neighborhood

This room is a "casita" (seperate living space) away from the house. It has a private entrance with a cypher lock on the door. The room has new carpet, new tile, and queen size bed. The Eastlake neighborhood is very safe and very quiet. We are located about 20 mins from the beach, downtown San Diego, and San Diego international airport. This location is only 2 miles from the Otay Ranch Mall.

Top Guest favourite
An open concept studio loft is depicted, featuring a light-filled living space. A comfortable sofa is positioned in the foreground, with a sliding barn door leading to a kitchenette and laundry area. Natural light streams through a large window, brightening the entire room.
Guesthouse in El Cajon
4.97 out of 5 average rating, 183 reviews

Mt Helix Studio Loft with Mountain Views

Mountain Views: Freshly renovated, quiet and spacious studio loft in private neighborhood. Close to coffee shops, grocery stores, and quick access to major highways. 500 sqft open concept. Laundry, Fast Internet, Cable TV and streaming services. Additionally, if you like oranges and avocados we grow them on the property (Seasonal of course). We also have a chicken coop and fresh eggs on request.

Top Guest favourite
A spacious studio room features a queen-sized bed with a blue comforter, enhanced by wooden beams overhead. A comfortable seating area includes a sofa and coffee table. Large glass doors open to a patio, allowing natural light to fill the space.
Guesthouse in La Mesa
4.99 out of 5 average rating, 282 reviews

Spacious, private Mt. Helix country style studio

Located in a quiet and lush neighborhood, in hills of La Mesa. This private studio has everything you need to relax and experience the California life: comfy queen size bed, full kitchen, patio, bbq, and fire pit. Within walking distance to Mt. Helix Historic Park for a spectacular 365-degree view of San Diego. You are 20 minutes from the beach, airport, and mountains.

Top Guest favourite
A newly remodeled bedroom features a spacious bed and warm wood furniture, including a dresser and a nightstand. A smart TV is mounted on the wall, while a kitchenette area displays a min fridge and microwave. The bathroom entrance is visible, with stylish decor seen beyond.
Guesthouse in La Mesa
4.99 out of 5 average rating, 147 reviews

Casa Sierra on Mount Helix

Enjoy a newly remodeled bedroom and bathroom with a private entrance. The space is completely separate from the rest of our home, offering peace, quiet, and total privacy. Inside, you’ll find a brand-new, comfortable bed, plus modern conveniences including a Smart TV, WiFi, mini fridge, microwave, and Keurig.

Top Guest favourite
The pool area features a clear swimming pool surrounded by lounge chairs, palm trees, and a shaded seating space. The scenic backdrop showcases mountains under a partly cloudy sky, emphasizing the tranquil outdoor atmosphere.
Guesthouse in La Mesa
5 out of 5 average rating, 413 reviews

Private Poolside Cabana

Poolside cabana with incredible mountain view in the Mt. Helix area. Located 20 mins - Downtown and beaches. 10 mins - SDSU and trolley. Bottle of wine waiting with comfortable King sized bed and luxury bathroom. Small kitchen area includes Keurig, microwave, blender, toaster and small fridge.

Popular amenities for Rancho San Diego guesthouses

Quick stats about guesthouse rentals in Rancho San Diego

  • Total holiday rentals

    Explore 10 holiday rentals in Rancho San Diego

  • Nightly prices starting at

    Rancho San Diego holiday rentals start at $154 NZD per night before taxes and fees

  • Verified guest reviews

    Over 1,720 verified reviews to help you choose

  • Wi-Fi availability

    10 of Rancho San Diego holiday rentals include Wi-Fi access

  • Popular amenities for guests

    Guests love Kitchen, Wi-Fi and Pool across Rancho San Diego rentals

  • 4.9 Average rating

    Rancho San Diego stays are highly rated by guests—averaging 4.9 out of 5!

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