
House holiday rentals in Santee
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Top-rated house rentals in Santee
Guests agree: These houses are highly rated for location, cleanliness and more.

Snazzy Spot with yard near beaches and downtown
Welcome to this modern get-away that is as bright and cheerful as a sunny day! You'll be sure to be rejuvenated here after your trips to the nearest beach (only a 15 minute drive) and outings on the town (only 10 minutes by car to downtown). This spot includes a private parking spot and a private yard. Yours to enjoy are a very comfortable queen bed, TV in bedroom, Fast WiFi, and a well stocked kitchenette. There are also two canyon hikes within a 2 minute walk with views of downtown for sunset.

SD Casita Sleeps 6 - Morey de Prieto Surf Ranch
The Morey de Prieto Surf Ranch is truly awesome! Reserve your stay in this 2 Bed/1 Bath 650 sq. ft. casita for six. Home includes a kitchen with many amenities including a GE electric cooktop, refrigerator, microwave and air fryer, rice cooker, Kitchenaid mixer, mixer for drinks, sink with prep trays, Moen faucet fixtures, gorgeous shower, Krups coffee maker, 50" smart TV equipped with WiFi and NetFlix, mountain views, workspace and a sofabed. How about a large deck with fire pit and BBQ?

Sunny & Spacious 3BR Retreat w/ Parking & A/C
Centrally located in La Mesa is this newly refurbished home ideal for business or pleasure with all of life’s little luxuries waiting for you to enjoy. The home features open concept living with a gourmet kitchen, a chic dining space, 3 beautiful bedrooms, 2 modern bathrooms and an expansive yard with an outdoor lounge. Walk 10 mins to Grossman Center with a Target, restaurants, cafes, a cinema & Walmart or drive to the heart of San Diego and all its attractions just 20 mins from your door.

The Glass House - A Nature Retreat
Enjoy a unique retreat; 180 degrees of views from inside the home. Nestled at the end of a private road, our place is nearby great hiking and countryside wineries. The Glass House provides a magical space and nature retreat where individuals, couples, families and friends can gather together to re-connect with nature, each other, and themselves. The breathtaking mountain top views, the huge deck, hot tub, fireplace, and the open concept living space is unbeatable for the perfect getaway.

Bright and spacious home with views, pool & spa.
This beautiful and recently remodeled, open-floor plan home is conveniently located directly across from Cowles Mountain, one of San Diego's most visited hiking trails. Each bedroom has its own full bathroom. Perfectly located for the outdoorsy family. Tons of hiking and mountain bike trails are just across the street. Only 15 min. away from beaches, zoo, & Sea World. Gaslamp/Downtown is only 20 min. by car. After a day of exploring, come home to a newly-built, salt-water pool and spa.

Cottage in the Garden! New! Modern!
COTTAGE IN THE GARDEN - New! Modern! Find beauty and serenity in this special guest house in one of San Diego's most desirable areas! Flowering bushes, plants, olive tree and fruit trees seen from all windows. All amenities: WiFi, Cable, serving dishes and tableware, full coffee bar, Ninja Blender, Flat screen TVs, 100% Egyptian Cotton Sheets or Boll and Branch Sheets (used by 3 Presidents), Japanese Toilette and more. 15 minutes to Downtown San Diego and 20 minutes to the beach!

Zen Retreat: 3-Bedroom Oasis near La Mesa Village
Relax in this charming 3-bedroom, 1-bathroom home located just 1 mile from the heart of Historic Downtown La Mesa Village. Nestled in a quiet, central neighborhood, this cozy retreat offers easy access to major freeways, top-rated restaurants, and the local trolley line making it a breeze to explore the best of San Diego. Within 10 to 15 miles, you’ll find yourself in iconic destinations like Downtown San Diego, Balboa Park, Coronado Island, scenic beaches, and beautiful mountain trails.

SDCannaBnB #2 *420 *parking *dog-friendly *hot tub
Welcome to SDCannaBnB - San Diego's premier cannabis-friendly rental! Our studio is newly remodeled with luxury ammenities. We proudly cater to the cannabis community and non-users alike. Our studio has HEPA air purifiers, is fully ventilated and receives deep cleanings between each guest. This ensures that every guest checks into a clean, fresh-smelling place that feels like home. Our studio is located in our quiet, fully fenced in backyard, close to San Diego's attractions

Mid-Century Style Family House with Spa
Beautiful Mt. Helix mid-century modern family home with incredible views, designed by architect of original Las Vegas, Desert Inn 3/4 acre.Less than 20 minute drive to beaches/Zoo/Sea World/Downtown, . With a swimming pool/hot tub, whole House have AC to. surrounded by California Oak/orange/lemonpomegranate trees and herb garden this home is the epitome of 1950’s luxury. A perfect family oasis, you won’t even want to leave the property. No loud parties please, this is a quite community.

(Relist!) Relax at a Stunning 1931 Historic Tudor!
Come & enjoy our 1931 historic tudor home! Beautifully rebuilt within the last 2 years. This house has a huge front lawn and space to roam. Enjoy the serenity this large property has to offer. Three peaceful patios to enjoy your morning coffee. The kitchen has an 48-inch 1950’s oven for the chef in the family. Bay windows, arched entryways and original light fixtures make this such a charming place to stay. Centrally located to enjoy everything San Diego & La Mesa has to offer.

Peaceful Casita | Firepit • Near SDSU
Welcome to our cozy home, perfect for couples visiting the area. It's also a great spot for SDSU parents visiting their kids. Conveniently close to the campus but far enough to enjoy some peace and quiet. If you enjoy this listing, click the heart icon ❤ in the top-right corner to bookmark it for easy access! Minutes from key attractions: ★ 6 min to SDSU/Viejas Arena ★ 14 min to Balboa Park ★ 17 min to Downtown SD (Gaslamp) ★ 19 min to San Diego Zoo ★ 21 min to the Airport

Glass Home with Views, Hot Tub, FREE EV Charging!
Update: We just installed a level 2 EV charger and are giving away free EV charging to the next 5 guests! Our modern, light-filled, scandinavian inspired home is a beautiful place to rest while you enjoy the magic of San Diego. The entire front of our home is glass with breathtaking views over the mountains and reservoir below. Neutral decor and warm wood accents provide a relaxing atmosphere and a tranquil setting.
Popular amenities for Santee house rentals
House rentals with a pool

Flamingo Sunset House: Sleeps 10: Pool + Hot Tub

Mid-Century Modern and Contemporary House

Custom Guesthouse, Balboa Park/Zoo/Hillcrest& pool

Updated TownHome, Great Location, Fantastic Views

Luxe Home w. Serene Backyard Spa

Stunning 3 bedroom w/Views! Game Room/Pool/Hot Tub

Oasis with ocean views/Pool/Hot tub! Sleeps 10!

Upscale Resort House /Views, Saltwater Pool/Spa !
Weekly house rentals

Tiny Home with a View

Airbnb Luxe: Designer Pool, Fitness and Office

A Perfect Pet Friendly Getaway.

Discover La Mesa: Your Perfect Cozy Base

Lakeside Deluxe 1-Bedroom

The Pool House

Cozy quiet getaway, great mattress (1-br)

Entire house, fenced yard, and driveway
Private house rentals

Spacious Home with Large Yard and Mountain Views

Vintage Vibes|King Bed|Big Screen|Backyard & Bunks

Jamul Hacienda | Couples Retreat | Pool & Views!

25% off, Pool, Hot Tub, BBQ, EV, Central-SD, SDSU

Modern, Private, & Stylish Home

Studio In Home with Private Entry

Quiet Country Home

Private House in the Hills, Pool, Pickleball court
When is the best time to visit Santee?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | $231 NZD | $212 NZD | $171 NZD | $260 NZD | $274 NZD | $219 NZD | $375 NZD | $329 NZD | $298 NZD | $197 NZD | $391 NZD | $377 NZD |
| Avg. temp | 15°C | 15°C | 16°C | 17°C | 18°C | 20°C | 21°C | 22°C | 22°C | 20°C | 17°C | 14°C |
Quick stats about house rentals in Santee

Total holiday rentals
Explore 50 holiday rentals in Santee

Nightly prices starting at
Santee holiday rentals start at $51 NZD per night before taxes and fees

Verified guest reviews
Over 1,390 verified reviews to help you choose

Family-friendly holiday rentals
30 properties offer extra space and kid-friendly amenities

Pet-friendly accommodation
Find 10 rentals that welcome pets

Holiday rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wi-Fi availability
50 of Santee holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Kitchen, Wi-Fi and Pool across Santee rentals

4.9 Average rating
Santee stays are highly rated by guests—averaging 4.9 out of 5!
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- Rentals with outdoor seating Santee
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- Family-friendly rentals Santee
- Rentals with a fire pit Santee
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- Rentals with a fireplace Santee
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- Rentals with a hot tub Santee
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