Lake house holiday rentals in Santee

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Top-rated lakehouse rentals in Santee

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Guest favourite
An outdoor deck features a hot tub, surrounded by trees and comfortable seating arrangements. A gas fire table is located nearby, creating a cozy atmosphere. The picturesque lake view extends beyond the railing, with a vibrant sunset painting the sky in warm hues.
Home in Lake Murray
4.95 out of 5 average rating, 115 reviews

Panoramic Lakefront with Hot Tub

Welcome to 'Sunshine and Naptime' - This newly renovated home is located on the Chapin side of Lake Murray. The entire house is newly furnished and full of amenities. This 3 bedroom lakefront cottage sits on a point with 180 degree panoramic views. Vaulted rustic pine ceilings showcase the wall to wall windows for a view that will take your breath away. You can watch the sunrise AND sunset from the living room or 600 sq ft deck. There is a hot tub, 2 kayaks, shuffle board & private dock.

Guest favourite
The exterior of the lakefront cottage features a green and brick facade, complemented by a red bench on the porch. A circular concrete path leads to the entrance, while surrounding greenery and trees add to the natural setting. Soft evening light enhances the inviting atmosphere.
Home in Manning
4.88 out of 5 average rating, 69 reviews

Cozy Church Branch Cabin

A cozy lakefront cottage made by family, for family. This was our parents home away from home, their favorite getaway. Now that they're gone, we want to share what they enjoyed. Traditionally constructed lake cabin with all the comforts of home. Large partially covered deck, large pier for fishing, plenty of room to bring your boat, canoes, or kayaks. Extremely close proximity to large landings where national fishing tournaments are held on Lake Marion. Prime hunting, near great hunting clubs.

Guest favourite
Two wooden Adirondack chairs are positioned on the dock, facing a calm Lake Murray. A small blue table is placed between the chairs. The water reflects the sky, creating a serene atmosphere with distant trees lining the opposite shore.
Home in Lake Murray
4.89 out of 5 average rating, 151 reviews

Lake Murray Family Retreat | BIG Water View Chapin

Lake Murray Family Retreat is a modest & cozy 3 bedroom, 2 bathroom home on an acre lot on Lake Murray, Chapin, SC with BIG views. We put a lot of thought into furnishing this home and had families in mind with each detail. It isn't the most updated or fanciest home on the lake, but it's one of the homiest! ★ 2 Queen beds + 3 twin beds (1 bunk + trundle) ★ 2 Full bathrooms ★ Smart TVs in the living room & primary bedroom ★ Gas fireplace ★ Firepit ★ Laundry area ★ Parking for 2 boats at dock

Guest favourite
A serene view of Lake Marion at sunset, with vibrant hues reflecting on the water. A wooden dock extends into the lake, surrounded by lush greenery. The soft contours of the shoreline are visible, creating a peaceful natural setting.
Home in Santee
4.91 out of 5 average rating, 68 reviews

Lakefront Lookout

The best panoramic views of Lake Marion! Whether you're out on the porch or indoors in our air-conditioned unit, you will not miss out on the beauty of the lake. Our updated kitchen and two full bathrooms are stocked with all the essentials. Hop on a boat, swim in the community pool, fish, walk, run, or bike the pedestrian bridge, or just hang out with your company while watching the boats go by. Please respect the fact that there is a small pet fee and we’re alerted when pets are present.

Top Guest favourite
The image captures a beautiful lakefront view, showcasing the serene waters of Lake Murray surrounded by trees. A private dock extends into the water, complemented by additional docks along the shoreline. The residential area and distant landscape add to the tranquil atmosphere.
Home in Lake Murray
4.97 out of 5 average rating, 173 reviews

Lakefront home on Lake Murray with private dock

Lakefront home on Lake Murray in Lexington, SC on over 1/2 an acre, 166 feet of waterfront with deep water, private dock, and entertainment space- perfect for an unforgettable vacation or weekend. Entire home for rent-4BR, 3 Bath +2 half baths, 2 sofa sleepers, sleeps 12. Breathtaking kitchen & large living space, perfect for the entire family. 2 single person kayaks, outdoor grill, 65 inch and 55 inch TV, washer/dryer, and fast wifi. Master suite with a lavish bathroom and soaking tub.

Guest favourite
Home in Summerton
4.93 out of 5 average rating, 14 reviews

Nanny’s Lake Retreat

Located in a quiet, dead end community. Enjoy the lake sounds from the spacious screened in porch. The porch has a swing, rocking chairs, and table with chairs. The den boasts a beautiful gas log fireplace and has two futons and a loveseat. The house is located in a golf cart community on a cove. Sandy beaches are just minutes away depending on the lake levels. Whether you’re looking for a vacation destination or fishing/hunting trip you will love this home. Pets require pre approval

Guest favourite
Home in Summerton
4.94 out of 5 average rating, 170 reviews

Luxurious Lakefront Log Home W/Pool & hot tub

Stunning luxury log home on the big waters of Lake Marion, featuring a private fishing pier, boat dock, brand-new saltwater pool, hot tub, and more. This custom-designed retreat offers 3 spacious bedrooms, a loft, and 2 elegant bathrooms—one with a clawfoot soaking tub and separate water closet. Enjoy dining and entertaining on the expansive screened-in porch with a custom 12’ outdoor bar. Just 6 minutes from I-95, this serene lakeside escape blends rustic charm with upscale comfort.

Guest favourite
A scenic view of the lake is presented, featuring a long dock extending into the calm water. Lush greenery and palm trees frame the foreground, while a faint rainbow appears in the backdrop under a partly cloudy sky.
Home in Santee
4.96 out of 5 average rating, 170 reviews

Santee lakefront home, big water right off I-95

Lakefront home on the big water of Lake Marion. This home is on the Santee side of the lake in a quiet neighborhood, 1-2 miles from restaurants, grocery stores, golf courses and I-95. Starbucks is less than 2 miles away. *Home can accommodate 10 guests max. *Indoor hot tub is available October through March. *Only registered guests listed on the booking are authorized at the property unless prior approval has been granted. *STRICT no pet policy. *PARTIES ARE STRICTLY PROHIBITED*

Guest favourite
The exterior of the home is showcased, highlighting a charming façade with a mix of brick and siding. Large windows reflect natural light, and the welcoming porch features seating. A landscaped yard and tall trees provide a serene backdrop, complementing the overall inviting atmosphere.
Home in Summerton
4.83 out of 5 average rating, 111 reviews

Perfect Family OFF THE GRID retreat at Lake Marion

Great water front family escape! Enjoy our beach, dock and boat ramp as well as our game room and fully stocked kitchen. We purchased our home is 2006 and began a complete interior and exterior renovation. In 2023 we installed solar panels and an electric vehicle charging station, yet we also have access to the grid for cloudy days and when power demand exceeds what our panels generate. We use a deep well for water. Bring your family for an off-the-grid vacation in our lake home!

Guest favourite
Home in Earlewood
4.93 out of 5 average rating, 143 reviews

KING Beds - Bungalow Downtown Cola

* KING Beds in both bedrooms * PET FRIENDLY * EV CHARGER PLUG (4 Prong outlet ONLY, no cord or adapter) * TVs in both bedrooms and living room * 1.4 miles from PRISMA Hospital (4-minute drive) * BLACKOUT CURTAINS in all the bedrooms * 15 minutes to Fort Jackson * 7 minutes to Riverbanks Zoo * 5 minutes to the Columbia Museum of Art and Soda City Market * HUGE Deck with table and small covered area * Off-street parking pad for 5+ cars * 11-minute drive to Lexington Medical Center

Top Guest favourite
A calm lake reflects soft hues of orange and pink during sunset. A wooden dock extends into the water, surrounded by lush green grass. Trees line the far shore, and a small boat is visible on the horizon, enhancing the serene landscape.
Home in Lake Murray
4.99 out of 5 average rating, 186 reviews

Anchors Aweigh

You'll enjoy this small cabin located less than 2 miles from Dreher Island State Recreation Area. The views from the living area and kitchen are breath-taking. You can sit on the dock & watch the sun set or take your boat out just a few hundred yards to watch the sun rise. This location is great for swimming & a dock is available so you can bring your boat. There is also great fishing from the dock and on a boat. This will provide an unforgettable vacation!

Top Guest favourite
A spacious deck overlooks a serene cove, featuring a dining table surrounded by six chairs. Lounge seating is positioned nearby, inviting relaxation. Lush trees frame the area, with views of water and nearby boats visible, creating a calm retreat.
Home in Summerton
4.99 out of 5 average rating, 124 reviews

Cheerful 3 bedroom home on the lake

Great 3 bedroom home on the water. Perfect for family vacations, a weekend getaway or a stay for local fishing tournaments. This home is on a quiet cove that opens up to the larger lake. Get the best of both worlds. The cove is perfect for paddle boating, kayaking, fishing off the dock, grilling on the deck, or just relaxing on the screened porch enjoying the view. But, with the private dock you can bring your boats and jet skis to enjoy the entire lake.

Popular amenities for Santee lakehouse rentals