House holiday rentals in Santee

The Grand Marshall

Bring the whole family to this renovated 3 BR, 2 bath home +1 BONUS ROOM, which serves as a theatre/game room with 2 queen sleeper sofas. Your family will enjoy: Coffee/beverage/snack bar Central location: Approximately 5 minutes to SC State and Claflin University, OC Tech College, Edisto Gardens, MUSC Health Orangeburg, shopping, dining, and more. Designated office space 1 king bed, 2 queen beds, plus 2 queen sleeper sofas 5 Roku Smart TV’s Smart lock for easy access High speed WiFi

Family · Location · Barbecue

Your home away from home in Pinopolis

Nestled at the end of a quiet cul-de-sac, this house is close to Lake Moultrie & the Cooper River. It’s also very close to popular wedding venues: Somerset Point, Pineland Village, & Old Santee Canal Park. Moncks Corner Recreational Complex, where many tournaments are hosted, is also about 3 miles away. Pinopolis is less than 20 miles from Summerville & the Volvo area, 40 miles from coastal beaches, and just 45 minutes away from Downtown Charleston. It’s a great location for work or play!

Value · Family · Getting around

Heated Indoor Pool on Lake Marion with Dock

Lake Marion Lakefront on a private 2.5 acres. Two houses - 4500 sq. ft. of space, plenty of room for 14! Dock to fish off of or bring your fishing boat. Heated indoor pool and Margaritaville-themed bar. Firepit, pool table, games, and dining table for 14 people. Great spot for Family Gatherings or Friends' Getaway. Golf, fishing, fruit picking, and amazing country food restaurants - 25 min drive. 5% Discount Gov. Employees :) Parties over 14 ppl ++ fees apply, details discussed prior.

Family · Location · Comfort

Lakefront Retreat | Dock, Firepit & Pet Friendly

Wake up to panoramic Lake Marion views, fish from your private dock, relax around the waterfront firepit, and enjoy a peaceful lakefront getaway just steps from the water. Enjoy peaceful mornings, sunset evenings, and easy access to fishing, boating, swimming, and lake life. Pet Friendly: Well-behaved pets are welcome! Please keep pets off furniture and clean up after them inside and outside the property. Multiple pets may be considered case-by-case—please message us before booking.

Location · Family · Nearby

Luxurious Lakefront Log Home W/Pool & hot tub

Stunning luxury log home on the big waters of Lake Marion, featuring a private fishing pier, boat dock, brand-new saltwater pool, hot tub, and more. This custom-designed retreat offers 3 spacious bedrooms, a loft, and 2 elegant bathrooms—one with a clawfoot soaking tub and separate water closet. Enjoy dining and entertaining on the expansive screened-in porch with a custom 12’ outdoor bar. Just 6 minutes from I-95, this serene lakeside escape blends rustic charm with upscale comfort.

Location · Family · Access

Pet-Friendly Lake Marion Getaway - Just off I-95!

In the quaint lakefront town of Santee, There exists a special place. Past Main street and down a country road, nestled in a modest lakefront community, with views of the majestic Lake Marion, we've worked tirelessly to create the perfect family retreat. No matter who you call family, this home is perfect for boaters, golfers, and nature enthusiasts. Guests at the Kindred Spirits Retreat experience more than just a beautiful home, they experience the joys of purposeful travel.

Value · Family · Layout

Sunny Santee Stay · 5BR Cityview · Lake & Golf

Brand new 2025 modern, cozy home near interstate I95, golf courses, markets, local restaurants (Cracker Barrel Old Country Store, Starbucks, etc) and Lake Marion. Santee is right in the middle distance between Miami and New York. Clean and stylish space with two 75” smart TVs, Wi-Fi, full amenities, and easy self check-in. Relax with the whole family at this new clean, quiet, safe and peaceful neighborhood. View our profile to explore more homes in the area.

Location · Family · Cleanliness

Cheerful 3 bedroom home on the lake

Great 3 bedroom home on the water. Perfect for family vacations, a weekend getaway or a stay for local fishing tournaments. This home is on a quiet cove that opens up to the larger lake. Get the best of both worlds. The cove is perfect for paddle boating, kayaking, fishing off the dock, grilling on the deck, or just relaxing on the screened porch enjoying the view. But, with the private dock you can bring your boats and jet skis to enjoy the entire lake.

Value · Family · Comfort

Cypress shores cottage. Lake Marion Sc

Relax and recharge in this cozy 2BR/1BA home just one row back from Lake Marion. Enjoy an equipped kitchen, bright living area, large streaming TV, and private yard and outdoor seating. Slight water views add to the charm, with marinas, boat landings, and fishing spots just minutes away. Perfect for families, couples, anglers, small groups, or remote workers seeking a peaceful retreat in Eutawville and the Lowcountry.

Location · Value · Bathroom

Boogs Cabin at Lake Marion

Boogs Cabin at the Lake is your cozy, laid back getaway on the big water of Lake Marion. With three comfortable bedrooms (1 King 2 Queen), bonus game room that also has a pull-out full bed and two sleeping cots, large sliding glass doors in the living room that invite natural light in and offer views of the great outdoors it's the perfect place to play, recharge and reconnect.

Family · Location · Air conditioning

Beautiful Lake Marion Townhome

Forget your worries in this spacious and serene space. Enjoy the beautiful lake view from our patio. 3 large bedrooms and 3 spacious bathrooms, along with a fully equipped kitchen and comfortable family room make this townhome an outstanding family retreat. 3 golf courses and beautiful Lake Marion make this a fine place to visit on a yearly basis.

Family · Value · Parking

Lake Marion | Chill, Cruise, or Cast a Line for 8!

Wake up to quiet mornings, sip coffee by the water, cast a line, and let the day slow down. This Lake Marion home is all about relaxing, fishing, and unplugging with your favorite people. This is the perfect place to reset, recharge, and enjoy the simple things. No rush. No noise. Just lake life, done right.

Location · Value · Cleanliness