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House holiday rentals in Cape Girardeau

Find and book unique houses on Airbnb

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Popular amenities for Cape Girardeau house rentals

House rentals with a pool

Superhost
Home in Cape Girardeau
4.29 out of 5 average rating, 7 reviews

Large Home, 2 King Beds, HotTub, Air Hockey, Games

BrandenRating, 5 stars2 months ago
We had a team of 9 for a week and the place had everything we needed! Abbie was a responsive host and the location was fantastic. Memories to be made and non stop conversation starters. One of the most fun air bnbs that I’ve been a part of over the years. Thank you!
Top Guest favourite
Home in Cobden
4.94 out of 5 average rating, 68 reviews

Wine trail, views, hot tub, pool…

ErikaRating, 5 stars2 weeks ago
Four of us stayed in Lisa's place for the weekend and we had more than enough space. The outdoor area was definitely our favorite amenity. Sitting outside anytime of the day with a beautiful view of the bluffs was special. I highly recommend staying here if you're in the area. It was a wonderful time.
Superhost
Home in Cape Girardeau
4.72 out of 5 average rating, 232 reviews

3+ acre:King Bed, Hot Tub, Mini Golf, Pool Table

ChristyRating, 5 stars1 month ago
Beautiful home - we felt very comfortable and enjoyed our time there.
Home in Carbondale
4.52 out of 5 average rating, 84 reviews

Peaceful Custom Carbondale Home w/ Pool, Near SIU!

HilaryRating, 5 stars6 months ago
Loved staying at this location. So close to restaurants and shops and outdoor adventures. Very quiet. Amazing views of stars. Plenty of sleeping spaces. Very responsive and helpful host!
Top Guest favourite
Home in Cobden
5 out of 5 average rating, 17 reviews

Champagne Domain

LauraRating, 5 stars1 month ago
We absolutely recommend! A beautiful location and a beautiful home! It was so relaxing and peaceful! The host went out of their way to make us feel at home. The home has a beautiful location and plenty of privacy. It was very clean and comfortable! Would absolutely book again.
Top Guest favourite
Home in Carbondale
5 out of 5 average rating, 20 reviews

Pond/Pool/Fire pit/Pet Friendly

MarissaRating, 5 stars5 days ago
This quaint and cozy place was a perfect stay for our road trip. The patio was a great spot to enjoy dinner! The weather wasn’t the best but we made the best of it and did enjoy the pool for a bit.
Superhost
Home in Carbondale
4.73 out of 5 average rating, 138 reviews

Brick Estate with pool in Quiet Neighborhood

MattRating, 5 stars1 week ago
Dave’s place was perfect for our family. There were 5 of us and we had plenty of room. It’s an older home, but has been kept up very well, and is very charming. The neighborhood is beautiful and we loved taking walks every day with our kids. Dave was very communicative and responded immediately if we ever had a question. Thank you Dave, we hope to be back soon!

Weekly house rentals

Superhost
Home in Alto Pass
5 out of 5 average rating, 11 reviews

Big Sky Cabin! On The WineTrail! Hot Tub! Fire Pit

RachelRating, 5 stars1 month ago
When 6 guests ranging from 13-79 all love the place, it’s a win!! It was so peaceful and we felt right at home! We had a blast with the arcade, pool table, & the hot tub! We highly recommend! Thanks to the host for going above expectations!
Top Guest favourite
Home in Cobden
5 out of 5 average rating, 48 reviews

South Pass Hideaway

MartinaRating, 5 stars2 weeks ago
This was the best Air B&B we have stayed at! The house looks just like the photos. Beds are extremely comfortable! Deanna was proactive in welcoming us to the home, making recommendations when needed and answered our messages immediately. She is the definition of a “super host”! We spent our time at Shawnee National Forest for 3 days. We enjoyed the peaceful surroundings in the evening around the fire and playing games with our 3 adult children. Thanks for sharing your home with us!
Top Guest favourite
Home in Altenburg
5 out of 5 average rating, 5 reviews

The Weber House in Altenburg

CharityRating, 5 stars3 months ago
The Weber house was a beautiful home away from home. My group and I spent two lovely days there. The home was very well taken care of; you could tell they had put a lot of time, effort and love into this space. It was extremely inviting, cozy and in pristine condition. Although the town was small, they still provided recommendations for food, shopping and entertainment within the small town as well as some of the surrounding areas. They were friendly and great at communicating. Never felt like we were in the dark about anything, and all expectations were communicated in advance. Highly recommend this property and host!
Guest favourite
Home in Altenburg
4.92 out of 5 average rating, 12 reviews

Gem in Heart of Altenburg

LauraRating, 5 stars2 months ago
beds are comfy, bathrooms were spacious and clean, cozy home and ample parking
Top Guest favourite
Home in Perryville
4.99 out of 5 average rating, 79 reviews

17 Acre Lake Retreat - Cash Lodge

KellyRating, 5 stars3 weeks ago
This was our second time there. We love it. Our kids love it. It was even chilly and rainy but the fishing was good and the kids swam anyway. We just have a relaxing time. We met Jim one of the caretakers he was full of information great guy. This will be on our yearly trip calandar for years to come.
Top Guest favourite
Home in Alto Pass
4.95 out of 5 average rating, 66 reviews

Alto Cabin-1/2 mile from 3 wineries!

JasonRating, 5 stars1 week ago
This was our second visit to Alto Cabin and we love it! It was pretty new when we first went, and now they’ve added a lot more touches that make it great like yard games and more kitchen supplies. We enjoyed lots of day trips for hiking and lounging in the hot tub at night. This is a place to go relax, not a place to go if you want the big city. Carbondale & Marion are both pretty close by and there are stores and a good butcher in Marion. The cabin is well equipped for cooking and has good WiFi for all your screening needs. We needed to contact the host one time for a question and she answered immediately. We are lucky to have found Alto cabin!
Top Guest favourite
Home in Cobden
4.97 out of 5 average rating, 38 reviews

The King's Quarters

AjRating, 5 stars6 days ago
We recently stayed at King’s Quarters, and it was truly an incredible experience! From the moment we arrived, we were impressed by how impeccably clean the cabin was. Every detail seemed to have been thoughtfully considered to ensure guest comfort. The high-quality towels and linens were a delightful touch, and we appreciated having an abundance of towels available. It was also a nice surprise to find snacks, hair dryers, and luxurious soap and shampoo provided. These little details made our stay feel extra special. The location of King’s Quarters is perfect for anyone looking for a peaceful retreat. It is very secluded, offering a serene atmosphere where it was hard to even notice a single neighbor. The climate control was excellent, keeping the cabin at a comfortable temperature throughout our stay. Overall, we had a fantastic time at King’s Quarters. It’s an ideal getaway for those seeking comfort and tranquility. We can’t recommend it highly enough.
Superhost
Home in Alto Pass
4.95 out of 5 average rating, 60 reviews

Havisham House - Main House

MeganRating, 5 stars11 months ago
The house is a wonderful combination of historic charm and modern convenience. It is beautiful while being comfortable and welcoming. We found the furniture comfortable and the provided supplies and amenities ready to meet all our needs. The grounds are gorgeous and although the house is conveniently located off a main road - you feel as though you have escaped to a beautiful haven. Jerri was a great host that helped answer all our question before and during our visit- Thank you Jerri! We had a few small issues when we were at the place, but these were all resolved quickly and did not impact our overall positive experience. When we arrived, the lock was not working and ultimately it needed batteries changed. This required a 20-30 min wait to get. We also had a few maintenance issues, but again Jerri was extremely responsive to these and got everything working quickly. We would not hesitate to stay here again or at any property managed by Jerri!

Private house rentals

Guest favourite
Home in Carterville
4.94 out of 5 average rating, 49 reviews

Experience Carterville Charm near Southern IL Univ

JasonRating, 5 stars2 weeks ago
Great place, recommend and would stay again
Top Guest favourite
Home in Cobden
4.96 out of 5 average rating, 79 reviews

Winery on Property and directly on Wine Trail

JoanRating, 5 stars1 week ago
We had 10 people and there was plenty of room. It was very clean. Michelle was very friendly and we enjoyed the Honey Meade next door. I would go back again.
Guest favourite
Home in Murphysboro
5 out of 5 average rating, 31 reviews

Sleeps 16! 7 Bedrooms! 8 Bathrooms! 8 Beds!

LauraRating, 5 stars1 week ago
We had a group of 15 and this home was absolutely perfect for our stay! There’s a ton of gathering space, especially in the living room where the large couch and footrest easily accommodated everyone. The multiple dining areas upstairs also made mealtimes easy and comfortable. The kitchen was incredibly well-stocked — we cooked every meal for all 15 of us without any issues. Having the extra fridge downstairs was a huge plus for storing all our food and drinks. The outdoor area is truly picturesque. We loved lounging on the deck, soaking in the peaceful surroundings, and listening to the local wildlife. All of the bedrooms were spacious, and it was a huge bonus that everyone upstairs had their own bathroom. The home had everything we needed and more — highly recommend for large groups!
Guest favourite
Home in Carbondale
4.98 out of 5 average rating, 45 reviews

Helen’s Country Home

BobRating, 5 stars2 weeks ago
We were four guys on a fishing trip, and Kathy's place was more than we needed and was much more than we expected. Very comfortable, maintained well. If your looking to relax in a quiet beautiful area, this fits the bill. Rooms very comfortable, more than enough bathrooms. Kathy provided some extra touches that we very considerate.
Guest favourite
Home in Carterville
4.94 out of 5 average rating, 70 reviews

SO. IL. 🌳🌜THE WOODLAND INN! 🌛🌳

ChrisRating, 5 stars2 weeks ago
We enjoyed our stay and found the house to be comfortable and peaceful. Relaxing on the back patio was particularly enjoyable under a canopy of a number (very) tall trees.
Top Guest favourite
Home in Murphysboro
4.99 out of 5 average rating, 68 reviews

Mary and Snooks' Cozy Country Farm House.

BobbiRating, 5 stars3 weeks ago
This Airbnb was EXACTLY what we needed for a stay near friends and family for a family occasion. This listing far exceeded our expectations and we are already planning to book again this summer! The place is beautiful, comfortable, and made us feel right at home. 10/10 recommend!
Top Guest favourite
Home in Cobden
4.95 out of 5 average rating, 61 reviews

StarView Vineyards | Winery Retreat

TerryRating, 5 stars3 weeks ago
Beautiful place . Right next door to Star View Winery . Very peaceful out in the countryside . I would recommend this Air Bnb to anyone . And the owner Regina was quick to respond to all our questions.
Top Guest favourite
Home in Herrin
4.97 out of 5 average rating, 74 reviews

Charming 3 bedroom retreat

JackieRating, 5 stars3 weeks ago
Kate's place had everything we needed. It was clean and comfortable. She was very fast at responding. I would stay again.

Quick stats about house rentals in Cape Girardeau

  • Total rentals

    70 properties

  • Nightly prices starting at

    $50 NZD before taxes and fees

  • Total number of reviews

    3K reviews

  • Family-friendly rentals

    40 properties are a good fit for families

  • Pet-friendly rentals

    20 properties allow pets

  • Rentals with dedicated workspaces

    40 properties have a dedicated workspace

Destinations to explore