Guesthouse holiday rentals in Charleston
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Top-rated Guesthouses in Charleston
Guests agree: These guesthouses are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for Charleston guesthouses
Family-Friendly guesthouses
Guesthouse in North Charleston
5.0 out of 5 average rating, 110 reviewsThe Park Circle Clerestory Studio Guest House
20–27 Jun
Guesthouse in Charleston
4.95 out of 5 average rating, 331 reviewsThe White House of Avondale
8–15 Oct
Guesthouse in Ridgeville
4.82 out of 5 average rating, 212 reviewsPond House Bungalow at Natural Gathering Grounds
5–12 Nov
Guesthouse in Charleston
4.91 out of 5 average rating, 647 reviewsIsland Oasis—Near Downtown
21–28 Oct
Guesthouse in North Charleston
4.86 out of 5 average rating, 441 reviewsPark Circle Jungalow Loft
7–14 Aug
Guesthouse in Johns Island
4.98 out of 5 average rating, 238 reviewsPrivate waterfront apt in the oaks
28 Dec – 4 Jan
Guesthouse in Summerville
4.94 out of 5 average rating, 211 reviewsNina's Cottage -Historic Downtown Summerville
16–23 Mar
Guesthouse in Summerville
4.87 out of 5 average rating, 747 reviewsNew Loft in Historic Summerville
4–11 Feb
Guesthouses with a patio
Guesthouse in Johns Island
4.91 out of 5 average rating, 104 reviewsCozy Cottage! 5 mins from Kiawah!
7–14 Oct
Guesthouse in Charleston
4.98 out of 5 average rating, 120 reviewsPrivate Backyard With Fire Pit, 15 Min to Downtown
12–19 Sep
Guesthouse in Charleston
4.97 out of 5 average rating, 125 reviewsStudio Apartment Minutes to Downtown Charleston
13–20 Apr
Guesthouse in Hanahan
4.99 out of 5 average rating, 76 reviewsThe Violet Villa w/ no cleaning fee
5–12 Aug
Guesthouse in Charleston
4.98 out of 5 average rating, 45 reviewsCountry in the City, "The Outback"
16–23 Apr
Guesthouse in Charleston
4.94 out of 5 average rating, 78 reviewsSpacious 1 bedroom cottage in Avondale
27 Mar – 3 Apr
Guesthouse in Goose Creek
4.96 out of 5 average rating, 49 reviewsThe Blue Secret
18–25 Jun
Guesthouse in Mount Pleasant
5.0 out of 5 average rating, 25 reviewsCoastal Charm: Village Hideaway
14–21 Dec
Guest house rentals with a washing machine and dryer
Guesthouse in Charleston
4.98 out of 5 average rating, 244 reviewsDetached Guest Suite
23–30 Jan
Guesthouse in North Charleston
4.94 out of 5 average rating, 111 reviewsNewly Renovated Studio in Park Circle
2–9 Jun
Guesthouse in Charleston
5.0 out of 5 average rating, 216 reviewsJames Island "La Casita" Nestled btw Beach & City
2–9 Oct
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 434 reviewsOld Mt. Pleasant/Shem Creek close to Sullivans/DT
30 Sep – 7 Oct
Guesthouse in Charleston
4.99 out of 5 average rating, 204 reviewsRedesigned suite! 12min to city, pet-friendly
11–18 Dec
Guesthouse in Charleston
4.99 out of 5 average rating, 140 reviewsLarge Guesthouse with Private Dock & Marsh Views
2–9 Sep
Guesthouse in Mount Pleasant
4.99 out of 5 average rating, 247 reviewsUpscale Couple's Escape | Beach & Downtown CHS
5–12 Jul
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 116 reviewsBeach, downtown, Alhambra Hall weddings so close!
28 Jul – 4 Aug
Quick stats about guesthouse rentals in Charleston
Total rentals
230 properties
Rentals with dedicated workspaces
100 properties have a dedicated workspace
Rentals with a pool
10 properties have a pool
Pet-friendly rentals
50 properties allow pets
Family-friendly rentals
40 properties are a good fit for families
Total number of reviews
23K reviews
Destinations to explore
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