Guesthouse holiday rentals in Charleston

Find and book unique guesthouse rentals on Airbnb

0 of 0 items showing
1 of 3 pages

Popular amenities for Charleston guesthouses

Family-Friendly guesthouses

Top Guest favourite
Guesthouse in Charleston
4.92 out of 5 average rating, 713 reviews

Island Oasis—Near Downtown

JasonRating, 5 stars1 week ago
Apartment was very clean and great location between the beach and downtown Charleston.
Guest favourite
Guesthouse in Mount Pleasant
4.97 out of 5 average rating, 251 reviews

Bungalow Under The Oaks

CheyenneRating, 5 stars2 weeks ago
If you’re looking for a cute little place to chill for the weekend, this is a great choice! While the bungalow is a little smaller than anticipated (for 2 adults/2dogs), the fully fenced yard makes up for everything else. The yard is pretty much completely shaded by beautiful oak trees, and my dogs loved every second we spent out there. The road is busy during the day, but at night, it quiets down, and all you can hear are the cicadas.
Top Guest favourite
Guesthouse in Summerville
4.88 out of 5 average rating, 803 reviews

New Loft in Historic Summerville

AngelinaRating, 5 stars2 days ago
Absolutely lovely. Cozy space, plenty of room for 2 people! Jacquelynn was great at responding and was very kind!
Guest favourite
Guesthouse in Mount Pleasant
4.94 out of 5 average rating, 255 reviews

Green Garden Studio @greengardenstudio2017

HelenRating, 5 stars1 month ago
This was the cutest above garage studio. It is very well done, clean and comfortable. The property is very well maintained- we would definitely stay here again! The AC was not working properly when we arrived but Holly responded immediately and got it working. Highly recommend!!
Top Guest favourite
Guesthouse in Charleston
5 out of 5 average rating, 109 reviews

Liz Lane Cottage- entire guesthouse

AnnaRating, 5 stars1 week ago
Our stay was amazing! Brooke was a fantastic host who always responded quickly and was very friendly whenever we saw her or her family. When we were caught in poor weather, she messaged me and gave us umbrellas so we could stay dry during our trip. A great experience and we all hope to stay here again!!
Guesthouse in Daniel Island
4.76 out of 5 average rating, 104 reviews

Exclusive, safe, quiet island living Charleston!

SarahRating, 5 stars4 months ago
I travel a lot for work. I always look for peaceful places that feel safe and have beautiful surroundings (in the event that I get to enjoy them on a work trip). Mo was a clear and responsive host. Parking is so easy in this neighborhood. The space is even more spacious in person than I expected. Thanks, Mo!
Superhost
Guesthouse in Charleston
4.84 out of 5 average rating, 118 reviews

Romantic Beach Style Cottage close to everything!

NatalieRating, 5 stars1 month ago
Clean & conscious hosts! Mindful of needs that may crop up, lovely home & family. Flexible! Perfect oasis away from the bustle of Charleston.
Top Guest favourite
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 138 reviews

5 STAR 1bd/1ba Shem Creek Retreat in #1 MtP area!

JonathanRating, 5 stars2 weeks ago
This was our second time at Treehouse and it was just as good as the first! Katey and Jules are great hosts. The location is amazing - 10 minutes to downtown Charleston and 10 minutes to the beach. We love walking down Coleman to Shem Creek and enjoying the sights and sounds of the marsh. We love patriots point park and taking the water taxi to downtown. You won’t find a better a place for a couple getaway!

Guesthouses with a patio

Guest favourite
Guesthouse in Mount Pleasant
4.96 out of 5 average rating, 131 reviews

*Old Village/Shem Creek Charmer*NEW 2BR Guesthouse

GloriaRating, 5 stars2 weeks ago
My husband and I had a wonderful 5 day stay at Georgia's apartment. Georgia's attention to detail was evident in each room. The furnishings and décor brings comfort and warmth to each space. We enjoyed a lunch of bbq ribs at Saltwater Cowboys (Shem creek) while we watched dolphins swim and pelicans dive for fish. We walked off our meal while striding down the Shem Creek boardwalk. We spent 2 days at Folly beach county park, soft sand and water temperature at 77F was lovely. We took advantage of the umbrella/sand chair rental which is delivered to your chosen beach spot. Upon request, Georgia provided us with big soft beach towels. Lastly, must say Mt. Pleasant is beautiful. I ran throughout the neighborhood (in training for a marathon), each house is beautifully distinctive, folks wave, and many bits of the town's history is displayed on sign plaques throughout. It was a great vacation for us!
Top Guest favourite
Guesthouse in Mount Pleasant
4.99 out of 5 average rating, 86 reviews

Coastal Charm: Village Hideaway

AlexRating, 5 stars1 week ago
Our stay at the Village Hideaway was perfect for our family! We actually live in Mount Pleasant and had water damage in our home and were having major repairs done to our flooring. We chose Christina’s place because of the location and because for a 2 bedroom place it was very spacious. It is a beautiful and cozy house, has great appliances, and it is extremely clean and well maintained. Christina was a great host, always available when needed, and very personable. I fully recommend the Hideaway to anybody who wants to stay in a private house close to the best of Mount Pleasant and a short drive to Charleston!
Top Guest favourite
Guesthouse in Charleston
4.95 out of 5 average rating, 122 reviews

Spacious 1 bedroom cottage in Avondale

RyanRating, 5 stars1 week ago
My partner and I really enjoyed staying at Derek and Sarah’s guest house cottage in Avondale. Even though it was located in a suburban area, we found the cottage feeling quiet and secluded once inside. The interior was cozy, the bed was comfortable, and the kitchen very usable to cook some of our meals. We drove to Charleston, and we found the parking space easy to use and clearly marked. Derek and Sarah were very friendly and responsive with any questions we had. With a car, it was an easy drive to our visit to Folly’s Beach, our carriage ride in the French Quarter, shopping at the Charleston City Market, the harbor area for our sunset cruise, the Magnolia Plantation and Gardens, the Charleston Tea Garden, and a lot more. It was a perfect launching pad for a really memorable trip.
Top Guest favourite
Guesthouse in Johns Island
4.96 out of 5 average rating, 127 reviews

Driftwood Cottage

LoghanRating, 5 stars2 days ago
Very clear and simple instructions, would stay here again!
Guest favourite
Guesthouse in North Charleston
4.91 out of 5 average rating, 140 reviews

My Happy Place

KellyRating, 5 stars5 days ago
This was mine and my wife's first time in the Charleston area. I highly recommend this host, we have nothing but great things to say. the ability to check in early, the recommendations to food, activities and places to see, the comfort of the home and the thoughtfulness of having them leave a beautiful note and a bottle of bubbly for us due to our 8 year anniversary. I couldn't have asked for anything else. Thank you very much for everything. I would definitely stay here again.
Top Guest favourite
Guesthouse in Hanahan
4.99 out of 5 average rating, 196 reviews

The Violet Villa w/no cleaning fee

GiaRating, 5 stars3 days ago
I didn’t want to leave! The description was accurate, but this community was more adorable than we ever imagined! Absolutely awesome and convenient! The hosts went above and beyond, and I’d stay here again and again. Super affordable and definitely one of our top Air BnB experiences to date.
Guest favourite
Guesthouse in Johns Island
4.9 out of 5 average rating, 184 reviews

Cozy Cottage! 5 mins from Kiawah!

ReneeRating, 5 stars3 weeks ago
My husband and I thoroughly enjoyed our stay in Lucy’s super cute cottage. It was clean, well appointed, and with the perfect amount of space for a couple. Although we didn’t get a chance to try it out (a little too chilly), the outdoor bathtub was a charming feature, in addition to the other outdoor spaces available. We loved the close proximity to the beach and to downtown Charleston. We felt very comfortable and rested really well. We would absolutely come back to Lucy’s cottage, and I’m sure you will feel the same way!
Top Guest favourite
Guesthouse in Riverland Terrace
5 out of 5 average rating, 64 reviews

Walk to restaurants! New, beautiful & clean home

ShelbyRating, 5 stars4 days ago
This is a great spot to either stay on the island or venture into downtown Charleston or other areas! 20 min away with traffic but there are multiple ways to get to and from where you want to go. Place looks just like the pictures & the water pressure in the shower is lovely!

Guest house rentals with a washing machine and dryer

Top Guest favourite
Guesthouse in West Ashley
5 out of 5 average rating, 124 reviews

Peaceful Garden Cottage Retreat

CharlesRating, 5 stars1 month ago
This was the perfect home base for our time in Charleston. It was conveniently located, spotless, and very peaceful. So much thought went into making our stay pleasurable. Looking forward to our return trip!
Top Guest favourite
Guesthouse in Mount Pleasant
4.99 out of 5 average rating, 158 reviews

Beach, downtown, Alhambra Hall weddings so close!

DerekRating, 5 stars3 days ago
Our stay at Robert’s place was excellent. The neighborhood was peaceful and quiet. It was easy to get to lots of different destinations from the place. We wouldn’t hesitate to stay there again.
Top Guest favourite
Guesthouse in Mount Pleasant
4.97 out of 5 average rating, 253 reviews

Cozy Apartment in Mount Pleasant

TaylorRating, 5 stars3 weeks ago
Dorothy's stay was perfect! It's such a cozy apartment and had everything we needed and more. The neighborhood is beautiful and it was easy to get to downtown Charleston (~15 min away) and other locations via Uber/Lyft. She was so easy to communicate with and quick to respond. I'd highly recommend!
Guest favourite
Guesthouse in West Ashley
4.9 out of 5 average rating, 624 reviews

Cozy Cottage w Games, Firepit, Grill, and More!

OliviaRating, 5 stars1 day ago
This airbnb is really cute! My friend and I enjoyed our stay. The guest house is so charming. We felt very comfortable staying there. The location was perfect, only 15 mins to downtown Charleston and less than 30 mins to get to several different beaches. I would recommend this place for anyone visiting Charleston that wants a cozy, quiet airbnb :)
Top Guest favourite
Guesthouse in Charleston
5 out of 5 average rating, 260 reviews

James Island "La Casita" Nestled btw Beach & City

CallieRating, 5 stars3 weeks ago
We enjoyed our stay so much! The space was very clean and neat. I quick drive to the beach and to the city! The James Island area was amazing! We will definitely stay again if we are in the area!
Top Guest favourite
Guesthouse in Charleston
5 out of 5 average rating, 177 reviews

The Guesthouse at Old Orchard

MichaelineRating, 5 stars2 days ago
Spent four nights with a friend in Brandy and Bill’s wonderful guest getaway and wish we could have stayed many more nights. Very clean and well appointed space — the kitchen had everything you need (and then some). Bathrooms were spacious and provided towels and washcloths. Beds were comfortable and there is so much space in this guesthouse. It’s in a quiet neighborhood and the property is very relaxing too. Brandy has created a cozy home away from home and we hope to return again. So many nice well appreciated touches. It’s perfectly located in the area too — so close to many of the attractions and also very close to grocery stores and restaurants. Highly recommend with no reservations!
Guest favourite
Guesthouse in Mount Pleasant
4.96 out of 5 average rating, 309 reviews

Shem Creek Bungalow: Coastal Comfort Redefined

NathanRating, 5 stars1 week ago
Stayed here on a recommendation and the place was perfect. Would recommend it to anyone interested in private little getaway.
Top Guest favourite
Guesthouse in Mount Pleasant
4.97 out of 5 average rating, 526 reviews

Old Mt. Pleasant/Shem Creek close to Sullivans/DT

GailRating, 5 stars1 week ago
We had a wonderful stay at the guesthouse. It is beautifully decorated and has everything you need for a great vacation. It also beach towels and chairs which we used each day. There are also bikes and helmets if you wish to take a ride. It was very peaceful and quiet yet still close to shopping and restaurants. It is a great location for a stay in Charleston! My husband and I want to make this our yearly vacation spot, we loved it here!

Quick stats about guesthouse rentals in Charleston

  • Total rentals

    220 properties

  • Total number of reviews

    25K reviews

  • Family-friendly rentals

    40 properties are a good fit for families

  • Pet-friendly rentals

    60 properties allow pets

  • Rentals with a pool

    10 properties have a pool

  • Rentals with dedicated workspaces

    100 properties have a dedicated workspace

Destinations to explore