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House holiday rentals in Guadalupe

Find and book unique houses on Airbnb

Top-rated house rentals in Guadalupe

Guests agree: These houses are highly rated for location, cleanliness and more.

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Top Guest favourite
Home in Baywood-Los Osos
4.99 out of 5 average rating, 111 reviews

The Los Osos Valley Guest House

Settle into authentic 'SLO CAL' in our cozy and casual Surf Ranchita - The Los Osos Valley Guest House is a rustic hideaway nestled between quaint rural farmlands, laid back Los Osos and the rugged natural coastline. It's a perfect base stay with it's casual rustic vibe, unique character and renovated modern conveniences. Enjoy a fully stocked 3 bedroom house with hot tub, infrared sauna, outdoor shower, 4 TVs private WiFi, heated marble floors, BBQ patio and outdoor seating with amazing views.

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Top Guest favourite
A red barn is situated in a spacious field, with horses grazing nearby. Rolling hills and trees create a serene countryside backdrop under a colorful sky at dusk. Fencing delineates the area, enhancing the open feel of the landscape.
Home in Arroyo Grande
4.93 out of 5 average rating, 100 reviews

Peaceful 3Br Haven in the hills

Relax at this unique and tranquil getaway. Our beachy bungalow is 4 miles from pismo beach, with wineries right down the road. Enjoy the beautiful views of rolling hills and towering trees of the countryside right from your window. Watch vibrant sunsets and sunrises from our backyard fire pit, or front porch living space. Visit with our goats, chickens, pigs, and horses on the property! Dogs ok, $25 pet fee. Larger house on the same property: airbnb.com/h/central-coast-beautifulcountryhome

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Superhost
The kitchen features rustic wooden beams and modern appliances, including a high-end cooking range and a farmhouse sink. A large window allows natural light to illuminate the space, while a handcrafted table and extra seating enhance functionality.
Home in Lompoc
4.81 out of 5 average rating, 286 reviews

Dare 2 Dream Farms Homestead

The large farmhouse is designed to elevate a gathering, bringing people together for large family meals and backyard entertainment, and replete with farm-life experiences. Gather ingredients from the farm-stand out front, watch the family farm in action as we garden and tend to the livestock, and enjoy the abundance of wild animals including deer, turkeys, and quail. The space is thoughtfully curated with old barnwood beams, abundant space to rest, and amenities to entertain the whole family.

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Guest favourite
A sunset sky filled with vibrant colors casts a warm glow over the country house. The exterior is highlighted by large windows and a welcoming entrance. The driveway leads towards the home, bordered by manicured landscaping, set against a backdrop of rolling hills.
Home in Arroyo Grande
4.83 out of 5 average rating, 309 reviews

Coastal Getaway, Country House, near 101 FWY

Country house surrounded by trees with many windows, wooden floors, lovely kitchen, large sunroom, and huge deck. All located just minutes from Pismo, Grover, Shell and Avila Beach, hot springs, hiking areas, wineries, golf courses, Lake Lopez, ATV riding & outlet shopping, Trader joe's and many other stores. San Luis Obispo is a lovely city just minutes north. and Hearst Castle is less than an hour's drive North. Conveniently situated off the 101 freeway, a nice retreat from the big city.

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Guest favourite
A vibrant backyard playground features a converted lifeguard tower, providing a unique play area above. Below, a ball pit filled with blue balls awaits playtime, while bubbles drift through the air. The space is surrounded by green turf, enhancing the playful atmosphere.
Home in Arroyo Grande
4.98 out of 5 average rating, 103 reviews

OMG Playground, close to Beach, Family Fun

Relax near the coast at this Nautical Themed retreat! This peaceful home is in a conveniently located neighborhood. It's an updated 3 bedroom, 2 bath home, with modern features. The gem of this property is the backyard/ playground where your family will enjoy hours of fun. Backyard includes a converted Lifeguard Tower/ Treehouse, a Lighthouse Play Fort, Ball Pit, Trampoline, & Sand Box. The home is approx. 2 miles to Pismo State Beach and 2 blocks to shopping such as Starbuck's & Aldi.

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Top Guest favourite
A single-story ranch house features a red-tiled roof and white stucco walls. Flanked by several trees, the entrance is accentuated by wooden double doors. The sky above is clear with soft clouds, contributing to the serene outdoor setting.
Home in Nipomo
4.9 out of 5 average rating, 175 reviews

Working Ranch~Golf, Beach,Wine/No smoking/Pet free

***At this time we are not set up to host weddings or public events.*** Escape the city to this ranch retreat surrounded by working farms. This 3-bedroom, 4-bath vacation home is on a full-time ranch in the heart of California’s Central Coast, halfway between Los Angeles and San Francisco, just 2 miles from Highway 101. Golf, wineries, and hiking are minutes away. Avila Beach, Pismo Beach, Cal Poly and San Luis Obispo are a 15–20 minute drive. Stays of 30+ days available upon request.

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Top Guest favourite
A small outdoor table is situated in a serene garden setting, featuring two wine glasses filled with red wine and a bottle nearby. A potted succulent adds a touch of greenery, surrounded by various plants, creating a tranquil atmosphere for relaxation.
Home in Santa Maria
4.96 out of 5 average rating, 153 reviews

Cozy Plant-Filled Loft | Near Wineries & Beaches

Stylish, plant-filled loft on the Central Coast! Relax under cozy lights surrounded by greenery in this peaceful, thoughtfully designed studio with everything you need. Enjoy a comfy living area with TV, kitchenette, WiFi, and private entrance for easy access. Located just minutes from Old Orcutt’s coffee shops, wine tasting rooms, and restaurants, with quick access to Solvang, SLO, and beaches. Perfect for a quiet getaway, work stay, or exploring the beautiful Central Coast.

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Guest favourite
A spacious bed is centered in the room, adorned with white linens and accented by two light blue pillows. A cozy yellow blanket is draped across the foot of the bed. Two bedside tables with modern lamps provide soft lighting, enhancing the calm atmosphere.
Home in Orcutt
4.96 out of 5 average rating, 231 reviews

Luxe Hideaway: Prvt Patio BBQ Winery, 20 min-Beach

Agreement: Bookings require a signed Renter Agreement, please check your email to complete booking. Kick back & relax in this calm, modern space. Enjoy the privacy of your own home with contactless check-in, high speed internet, comfortable beds, pull-out memory foam sofa sleeper for added guests, full kitchen just waiting for your culinary desires, and a patio with dining set for 6. Enjoy being centrally located while you explore the beautiful central coast.

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Guest favourite
A light and airy kitchen features a wooden dining table surrounded by curved-backed chairs. A vintage-style refrigerator and stove are visible, complemented by a pendant light hanging above. Natural light enhances the warm wooden tones of the cabinetry and flooring, creating a welcoming cooking space.
Home in Los Alamos
4.87 out of 5 average rating, 390 reviews

Wine cellar House

Welcome to Bodega House, a restored 1920s farmhouse in the center of Los Alamos. The home features a serene queen bedroom and a separate lounge space, along with a sleeper sofa in the living area. Thoughtfully designed for two adults, the house can also comfortably host one to two children on the sleeper sofa. It’s an ideal setting for couples or small families seeking the ease and privacy of a home while being just steps away from the best of Los Alamos.

ValueFamilyWi-Fi

Guest favourite
A bright and airy living space features a large window allowing natural light to fill the area. The room includes a cozy seating arrangement with a gray sofa, a wooden dining table with chairs, and decorative wall baskets. A kitchenette is visible in the background.
Home in San Luis Obispo
4.96 out of 5 average rating, 393 reviews

Wine Country Hilltop Retreat

Kick back and relax in this calm, stylish space with spectacular Edna Valley views. Read a book on your hillside patio and see buffalo and longhorns grazing in neighboring fields. After an incredible sunset, unwind by your firepit at night under a sky full of stars. This private country escape is also at the center of it all - 15 minutes to beaches & Cal Poly, 5 minutes to airport & 20+ wineries/tasting rooms, 10 minutes to beautiful downtown SLO.

ValueFamilyQuiet

Guest favourite
A bright living room is presented with natural light streaming through a window. Two comfortable chairs with soft throw blankets face a modern TV mounted on a pale wall. Decorative plants enhance the space, complemented by a wooden coffee table and light hardwood flooring.
Home in Arroyo Grande
4.93 out of 5 average rating, 266 reviews

Mid-century home in the heart of Arroyo Grande.

Welcome to the Eman House! I can't wait to host you at the 1950's mid century in Arroyo Grande, CA. Enjoy the beautiful remodeled kitchen, private backyard and patio, and two cozy bedrooms while soaking up the best of the central coast. Just a 10 minute walk to the historic Arroyo Grande village, a 5 minute drive to the beaches of Grover, and tucked away in one of Arroyo Grande's most peaceful cul-de-sacs.

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Superhost
A modern two-story home is depicted, showcasing a light-colored exterior with dark trim. The front yard features low-maintenance landscaping with desert plants. A driveway leads to the garage, and neighboring homes are visible in a suburban setting under a clear blue sky.
Home in Guadalupe
4.85 out of 5 average rating, 271 reviews

Beach home near golf, wineries, dunes & Vandenburg

This Pasadera home has three bedrooms two and a half bathrooms with a loft which has a fold out couch. The downstairs couch will sleep 2 more if needed so 9 people will fit. It’s just a few miles away from Trilogy and Blacklake golf course, the beach, shopping , golf courses and many wineries! It’s a perfect beach community. About 20 minutes to Vandenburg Air Force base.

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