
House holiday rentals in Guadalupe
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Top-rated house rentals in Guadalupe
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The Los Osos Valley Guest House
Settle into authentic 'SLO CAL' in our cozy and casual Surf Ranchita - The Los Osos Valley Guest House is a rustic hideaway nestled between quaint rural farmlands, laid back Los Osos and the rugged natural coastline. It's a perfect base stay with it's casual rustic vibe, unique character and renovated modern conveniences. Enjoy a fully stocked 3 bedroom house with hot tub, infrared sauna, outdoor shower, 4 TVs private WiFi, heated marble floors, BBQ patio and outdoor seating with amazing views.
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Coastal Getaway, Country House, near 101 FWY
Country house surrounded by trees with many windows, wooden floors, lovely kitchen, large sunroom, and huge deck. All located just minutes from Pismo, Grover, Shell and Avila Beach, hot springs, hiking areas, wineries, golf courses, Lake Lopez, ATV riding & outlet shopping, Trader joe's and many other stores. San Luis Obispo is a lovely city just minutes north. and Hearst Castle is less than an hour's drive North. Conveniently situated off the 101 freeway, a nice retreat from the big city.
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OMG Playground, close to Beach, Family Fun
Relax near the coast at this Nautical Themed retreat! This peaceful home is in a conveniently located neighborhood. It's an updated 3 bedroom, 2 bath home, with modern features. The gem of this property is the backyard/ playground where your family will enjoy hours of fun. Backyard includes a converted Lifeguard Tower/ Treehouse, a Lighthouse Play Fort, Ball Pit, Trampoline, & Sand Box. The home is approx. 2 miles to Pismo State Beach and 2 blocks to shopping such as Starbuck's & Aldi.
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Hillside view with hot tub too
This house is the 2nd home on the property (main home is also STR). Located at the top of a private driveway with a beautiful view of the hills. Fully stocked kitchen with fridg/freezer, dishwasher, oven, 5 burner stove, microwave, ice maker, osmosis system, fully automatic espresso maker. 65” QLED TVs in living room and bedrooms. Patio furniture wiith covered gazebo, gas BBQ, pellet smoker/BBQ, patio heaters, fire table. Hot tub with gazebo accommodates 6. EV/Tesla charger in garage.
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Eagle Creek Ranch 1/2 Block from Bell Street
Eagle Creek Ranch is my special place. I fell in love with it and I knew it was for me. I continue to pour my heart into the property and I love to share with others. The wifi is good. Several times a year it might be out for a few hours or so . There is ample parking. You might see the resident bobcat and fox through every day. You’re a 10 second walk from downtown Bell Street. Freeway, east of property, can be heard on north side of house only. Small gatherings allowed (w/ permission).
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Working Ranch~Golf, Beach,Wine/No smoking/Pet free
***At this time we are not set up to host weddings or public events.*** Escape the city to this ranch retreat surrounded by working farms. This 3-bedroom, 4-bath vacation home is on a full-time ranch in the heart of California’s Central Coast, halfway between Los Angeles and San Francisco, just 2 miles from Highway 101. Golf, wineries, and hiking are minutes away. Avila Beach, Pismo Beach, Cal Poly and San Luis Obispo are a 15–20 minute drive. Stays of 30+ days available upon request.
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Cozy Plant-Filled Loft | Near Wineries & Beaches
Stylish, plant-filled loft on the Central Coast! Relax under cozy lights surrounded by greenery in this peaceful, thoughtfully designed studio with everything you need. Enjoy a comfy living area with TV, kitchenette, WiFi, and private entrance for easy access. Located just minutes from Old Orcutt’s coffee shops, wine tasting rooms, and restaurants, with quick access to Solvang, SLO, and beaches. Perfect for a quiet getaway, work stay, or exploring the beautiful Central Coast.
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Luxe Hideaway: Prvt Patio BBQ Winery, 20 min-Beach
Agreement: Bookings require a signed Renter Agreement, please check your email to complete booking. Kick back & relax in this calm, modern space. Enjoy the privacy of your own home with contactless check-in, high speed internet, comfortable beds, pull-out memory foam sofa sleeper for added guests, full kitchen just waiting for your culinary desires, and a patio with dining set for 6. Enjoy being centrally located while you explore the beautiful central coast.
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Wine cellar House
Welcome to Bodega House, a restored 1920s farmhouse in the center of Los Alamos. The home features a serene queen bedroom and a separate lounge space, along with a sleeper sofa in the living area. Thoughtfully designed for two adults, the house can also comfortably host one to two children on the sleeper sofa. It’s an ideal setting for couples or small families seeking the ease and privacy of a home while being just steps away from the best of Los Alamos.
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Guesthouse in Ballard
Enjoy the serenity of Ballard in this charming neighborhood. A quiet respite from the hustle & bustle in a beautiful setting. Our home was built around 1911 & recently restored, keeping its original character in tact. A short walk to the delicious Bob's Well Bread & the Ballard Inn Restaurant. Not to mention down the road from wine tasting, delicious restaurants & shopping. Come relax & enjoy this beautiful home & great location as much as we do.
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Wine Country Hilltop Retreat
Kick back and relax in this calm, stylish space with spectacular Edna Valley views. Read a book on your hillside patio and see buffalo and longhorns grazing in neighboring fields. After an incredible sunset, unwind by your firepit at night under a sky full of stars. This private country escape is also at the center of it all - 15 minutes to beaches & Cal Poly, 5 minutes to airport & 20+ wineries/tasting rooms, 10 minutes to beautiful downtown SLO.
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Mid-century home in the heart of Arroyo Grande.
Welcome to the Eman House! I can't wait to host you at the 1950's mid century in Arroyo Grande, CA. Enjoy the beautiful remodeled kitchen, private backyard and patio, and two cozy bedrooms while soaking up the best of the central coast. Just a 10 minute walk to the historic Arroyo Grande village, a 5 minute drive to the beaches of Grover, and tucked away in one of Arroyo Grande's most peaceful cul-de-sacs.
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Popular amenities for Guadalupe house rentals
House rentals with a pool

Getaway at the Highlands+Heated Pool+Hot Tub
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Spacious SLO CAL Home w/ Pool, Spa. Pet Friendly!
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Historic 1895 Edna Railhouse with Heated Pool
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Heated pool, arcade, walk to tasting rooms
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Los Olivos Wine Country Stunner - Walk to downtown
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Pool & view in Sta Rita Hills Wine Country, Lompoc
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Hidden Views
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Ranch Style Home w/ Bikes! Heart of Wine Country
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Weekly house rentals

Luxury Village Home
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Serenity On Serrano
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Casa Del Mar
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Dare 2 Dream Farms Homestead
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Windermere Villa-Jacuzzi, Ocean Views,Ping Pong
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Mid Century Modern Loft Downtown SLO
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|Safe|BBQ | Hot Tub| 4 Bedrooms| Deck With Views
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The Quailhouse on Ranch near Avila Beach
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Private house rentals

San Luis Obispo Wine Country Retreat
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Cute Grover Beach cottage STR-0068
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CA dreaming in Wine Country!
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Charming Coastal Retreat w/Hot Tub-5min to Beach
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Well Appointed 3BR Home | Steps to Town |Fireplace
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Perfect Central Coast Getaway Retreat Close to All
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Beach, Wine Country, & Golf adjacent home for 8
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Spacious Whole Residence w/ Bikes--Close to Beach!
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Destinations to explore
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- Cayucos Beach
- Pismo State Beach
- El Capitán State Beach
- Morro Strand State Beach
- Montaña de Oro State Park
- Cayucos State Beach
- Los Padres National Forest
- Morro Rock Beach
- California Polytechnic State University
- Dinosaur Caves Park
- Sensorio
- Mission San Luis Obispo de Tolosa
- Pismo Preserve
- Charles Paddock Zoo
- Monarch Butterfly Grove
- Vina Robles Amphitheatre
- Tablas Creek Vineyard
- Downtown City Park
- Nojoqui Falls Park
- Talley Vineyards
- Harmony Headlands State Park
- Adelaida Vineyards & Winery
- Fess Parker Winery & Vineyard
- Solvang Windmill





