
House holiday rentals in La Mesa
Find and book unique houses on Airbnb
Quick stats about house rentals in La Mesa

Total holiday rentals
Explore 340 holiday rentals in La Mesa

Nightly prices starting at
La Mesa holiday rentals start at $53 NZD per night before taxes and fees

Verified guest reviews
Over 15,230 verified reviews to help you choose

Family-friendly holiday rentals
220 properties offer extra space and kid-friendly amenities

Pet-friendly accommodation
Find 120 rentals that welcome pets

Holiday rentals with a pool
80 properties feature pools

Rentals with dedicated workspaces
220 properties have a dedicated workspace

Wi-Fi availability
340 of La Mesa holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Kitchen, Wi-Fi and Pool across La Mesa rentals

4.9 Average rating
La Mesa stays are highly rated by guests—averaging 4.9 out of 5!
Top-rated house rentals in La Mesa
Guests agree: These houses are highly rated for location, cleanliness and more.

Family Fun! Game Garage + Big Yard + Free Parking
Embodying the epitome of cool! This home has the perfect blend of a vintage feel with a modern touch. Stepping inside, you’re greeted by an atmosphere of fun & creativity. A large private serene retreat in the backyard w/abundant seating and fire pit. Huge 3-car garage bonus space with games. Located just minutes from downtown La Mesa, many dining options & conveniences. Everything you need & more! Distance to: San Diego Zoo: 18 min Sea World: 23 min SDSU: 13 min Airport: 19 min Gaslamp: 18 min
ValueLocationBathroom
4.94 out of 5 average rating, 163 reviews
*NO TAX*/Heated Pool/Hot Tub/Pizza Oven/Playground
Escape to our luxury 5bd/4ba retreat with San Diego’s best backyard on a massive 10,000+ sqft lot: ✨SAVE 10.5% TAX!✨ 🏖️ Heated saltwater pool*, hot tub, outdoor shower 🍕 Outdoor lounge w/ TV, fire pit, pizza oven, BBQ 🍊 Abundant free-to-pick blood orange, passionfruit, avocado, macadamia trees 🎥 Giant movie projector + screen 🛝 Kids playground 🐶 Dog-friendly Ideal for groups, this private haven sits by Lake Murray’s beautiful hiking trails for the perfect mix of relaxation & adventure!
FamilyLocationCleanliness
4.9 out of 5 average rating, 116 reviews
Sunnyside Resort Spa, Beach, Zoo, Arcade
SEND US A MESSAGE FOR SPECIAL OFFER! Imagine booking the most memorable experience with your party! Kick back and relax in a safe, stylish casita. Check in contactless and enjoy! Cozy, comfy, and a perfect base for exploring the city. Cook your own meal in the alluring kitchen or enjoy your meal at the cute dining area outside. Great for family's or trips with friends! The entire guest house is is 5 minutes from SDSU, 15 minutes from the beach and 15 minutes from downtown San Diego! Enjoy
ValueFamilyParking
4.89 out of 5 average rating, 142 reviews
Large Home Heated Pool Spa | Game Room (Sleeps 30)
Gather your friends and family for the ultimate getaway at this spacious paradise! Featuring a sparkling pool, soothing spa, BBQ pit, and cozy fire pit, there’s endless fun for everyone. The game room is packed with entertainment options, perfect for some friendly competition or unwinding after a day in the sun. Designed to host large groups comfortably, this home is ideal for reunions, celebrations, or just a relaxing escape! This home offers everything you need for an unforgettable stay!
ValueLocationOutdoor spaces
4.83 out of 5 average rating, 131 reviews
Zen Retreat: 3-Bedroom Oasis near La Mesa Village
Relax in this charming 3-bedroom, 1-bathroom home located just 1 mile from the heart of Historic Downtown La Mesa Village. Nestled in a quiet, central neighborhood, this cozy retreat offers easy access to major freeways, top-rated restaurants, and the local trolley line making it a breeze to explore the best of San Diego. Within 10 to 15 miles, you’ll find yourself in iconic destinations like Downtown San Diego, Balboa Park, Coronado Island, scenic beaches, and beautiful mountain trails.
ValueFamilyShared spaces
4.96 out of 5 average rating, 143 reviews
Cottage in the Garden! New! Modern!
COTTAGE IN THE GARDEN - New! Modern! Find beauty and serenity in this special guest house in one of San Diego's most desirable areas! Flowering bushes, plants, olive tree and fruit trees seen from all windows. All amenities: WiFi, Cable, serving dishes and tableware, full coffee bar, Ninja Blender, Flat screen TVs, 100% Egyptian Cotton Sheets or Boll and Branch Sheets (used by 3 Presidents), Japanese Toilette and more. 15 minutes to Downtown San Diego and 20 minutes to the beach!
LocationValueView
4.94 out of 5 average rating, 251 reviews
SDCannaBnB #2 *420 *parking *dog-friendly *hot tub
Welcome to SDCannaBnB - San Diego's premier cannabis-friendly rental! Our studio is newly remodeled with luxury ammenities. We proudly cater to the cannabis community and non-users alike. Our studio has HEPA air purifiers, is fully ventilated and receives deep cleanings between each guest. This ensures that every guest checks into a clean, fresh-smelling place that feels like home. Our studio is located in our quiet, fully fenced in backyard, close to San Diego's attractions
LocationValueHospitality
4.99 out of 5 average rating, 360 reviews
Mid-Century Style Family House with Spa
This home is the epitome of 1950’s luxury. A perfect family oasis, you won’t even want to leave the property. Beautiful Mt. Helix mid-century modern family home with incredible views, designed by architect of original Las Vegas Desert Inn situated on nearly an acre. Less than 20 minute drive to beaches/Zoo/Sea World/Downtown. With a swimming pool, jacuzzi, and AC. Surrounded by orange, lemon, pomegranate trees and herb garden. No loud parties please, this is a quiet community.
LocationValueCondition
4.99 out of 5 average rating, 205 reviews
Palm Cottage San Diego
Palm Cottage sits in the heart of La Mesa Village, San Diego. Enjoy the charm of a historic home with a fully remodeled and stylish interior featuring both Dutch & French doors letting in plenty of sunshine. A large private yard w/ covered outdoor living area creates the ultimate indoor/outdoor lifestyle. You're steps from the local grocery store, village shopping, coffee shops, restaurants, bars and the trolley. You could not ask for a better location!
LocationValueQuiet
4.94 out of 5 average rating, 150 reviews
QUIET HOME -3 Bedroom & Den, + POOL, sleep 8 plus
Welcome to the La Mesa Pool House! Our cozy house in La Mesa is the perfect place to relax and recharge with the family. This house is walking distance to many great La Mesa eateries such as Terra Restaurant and Surf and Soul. We are also located just 10 minutes away from San Diego State University and we are less than 20 minutes from all major attractions in San Diego: downtown, Little Italy, Zoo, Sea World, beaches and more!
FamilyValueParking
4.9 out of 5 average rating, 115 reviews
SDSU Beach Cottage
Welcome to our charming SDSU Beach Cottage! Centrally located in a desirable San Diego neighborhood, you're just 10 minutes from many of the city's top attractions. Steps away, you'll find popular local dining, a wine bar, pub, natural market, pizza shop, nail salon, liquor store, and Einstein Bros. Bagels. Enjoy San Diego's best or unwind in our tropical backyard featuring outdoor games and ping pong. Minimum age to book: 25.
LocationFamilyNearby
4.97 out of 5 average rating, 401 reviews
Spacious & Fun | 5br, 4.5ba | Hot Tub | Views
Experience sunny San Diego from this 5 bedroom, 4.5 bathroom foothill home. Wake up to panoramic views of the surrounding hillsides and gather in the spacious living and dining rooms. The home is conveniently located just 15-20 minutes from San Diego's famous beaches and top attractions. After a day of exploration, unwind in the backyard area featuring a hot tub, fire pit, pool table, and life-sized chessboard.
ValueLocationIndoor spaces
4.99 out of 5 average rating, 133 reviewsPopular amenities for La Mesa house rentals
House rentals with a pool

San Diego Oasis- A Retro Retreat w/ King Size Bed!
LocationFamilyPets
4.92 out of 5 average rating, 102 reviews
Family Pool Retreat + Gym, Fire Pits, Views (Sleep
FamilyLocationParking
4.93 out of 5 average rating, 252 reviews
Beautiful 3,000 Sq Ft Tropical Oasis
FamilyValueParking
4.96 out of 5 average rating, 179 reviews
The Agave House | Mountain Views & Pool
LocationFamilyAir conditioning
4.81 out of 5 average rating, 104 reviews
San Diego Pool | Fire Pit | Sunshine | Sleeps 10
FamilyLocationGetting around
4.85 out of 5 average rating, 264 reviews
ModernCoastal I View I Pool ITub
LocationFamilyBeach
4.98 out of 5 average rating, 116 reviews
San Diego Pool House with Luxury King/Queen Suites
ValueFamilyBarbecue
4.95 out of 5 average rating, 110 reviews
Upscale Resort House /Views, Saltwater Pool/Spa !
LocationFamilyNearby
4.96 out of 5 average rating, 227 reviewsWeekly house rentals

Beautiful Mid-Century Home on Tree Lined Street!
ValueFamilyQuiet
4.91 out of 5 average rating, 105 reviews
Private cozy house
ValueLocationParking
4.89 out of 5 average rating, 269 reviews
Travel Writer's Pad
FamilyLocationTV
4.98 out of 5 average rating, 341 reviews
Cozy 4bd Family Home near all SD Attractions!
ValueFamilyParks
4.85 out of 5 average rating, 427 reviews
Sleeps 16 | Hot Tub & Fire Pit | 5BR Reunion Home
LocationValueGetting around
4.9 out of 5 average rating, 126 reviews
San Diego Retreat ·Jacuzzi + Billiards +Sleeps 12!
LocationFamilyKitchen
4.96 out of 5 average rating, 101 reviews
Newer "Manor Studio"
ValueLocationNearby
4.86 out of 5 average rating, 273 reviews
Newly Built Upscale Home with 5 Bedrooms/6 Baths
ValueLocationCleanliness
4.99 out of 5 average rating, 156 reviewsPrivate house rentals

The Sand House-Gorgeous 3BR-2B HotTub+FirePit+Turf
LocationValueNearby
4.95 out of 5 average rating, 82 reviews
Downtown La Mesa gem
ValueLocationGetting around
4.94 out of 5 average rating, 85 reviews
Panoramic San Diego Views • Fire Pit • Sleeps 9
LocationFamilyAccuracy
4.95 out of 5 average rating, 44 reviews
La Mesa Village Spanish Cottage
LocationFamilyIndoor spaces
4.86 out of 5 average rating, 42 reviews
Panoramic Ocean View Retreat - Family Friendly
FamilyLocationParking
4.92 out of 5 average rating, 38 reviews
Oliver House in La Mesa
FamilyLocationCheckout
4.92 out of 5 average rating, 60 reviews
Sunny La Mesa Home w/ Pool & Spa | Family Friendly
FamilyLocationBeach
4.97 out of 5 average rating, 29 reviews
Tiny Home with a View
ValueLocationOutdoor spaces
5.0 out of 5 average rating, 55 reviewsWhen is the best time to visit La Mesa?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sept | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | $327 NZD | $347 NZD | $378 NZD | $371 NZD | $407 NZD | $437 NZD | $442 NZD | $373 NZD | $327 NZD | $332 NZD | $347 NZD | $352 NZD |
| Avg. temp | 15°C | 15°C | 16°C | 17°C | 18°C | 20°C | 21°C | 22°C | 22°C | 20°C | 17°C | 14°C |
Destinations to explore
- San Diego Holiday rentals
- Los Angeles Holiday rentals
- Phoenix Holiday rentals
- Las Vegas Holiday rentals
- Paradise Holiday rentals
- Scottsdale Holiday rentals
- Big Bear Lake Holiday rentals
- Palm Springs Holiday rentals
- Joshua Tree Holiday rentals
- Tijuana Holiday rentals
- Santa Barbara Holiday rentals
- Ensenada Holiday rentals
- Guesthouse rentals La Mesa
- Rentals with a hot tub La Mesa
- Rentals with pools La Mesa
- Private suite rentals La Mesa
- Family-friendly rentals La Mesa
- Pet-friendly rentals La Mesa
- Rentals with breakfast La Mesa
- Villa rentals La Mesa
- Apartment rentals La Mesa
- Rentals with beach access La Mesa
- House rentals San Diego County
- House rentals California
- House rentals United States
- SeaWorld San Diego
- Rosarito Beach
- Coronado Beach
- LEGOLAND California
- University of California-San Diego
- Petco Park
- San Diego Zoo
- San Diego Convention Center E Ent
- San Diego Zoo Safari Park
- Pacific Beach
- San Diego State University
- Balboa Park
- Tijuana Beach
- Pechanga Resort Casino
- Torrey Pines State Beach
- Mission Beach
- Las Olas Resort & Spa
- Ocean Front Walk
- Anza-Borrego Desert State Park
- Oceanside City Beach
- La Misión Beach
- Moonlight State Beach
- Belmont Park
- Sesame Place San Diego





