
Guesthouse holiday rentals in Mission Bay, San Diego
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Top-rated Guesthouses in Mission Bay, San Diego
Guests agree: These guesthouses are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for Mission Bay, San Diego guesthouses
Family-Friendly guesthouses

Adorable San Diego Guesthouse

Poolside Ocean View Studio

Fig Tree Bungalow

Pacific Beach Guest House With Garage and A/C

The BEST NEST Clean, peaceful, private, affordable

Granny Flat with Bedroom/Bathroom/Kitchen

Charming North Park Cottage

San Diego family bungalow!
Guesthouses with a patio

Adorable cottage in Talmadge

Private 1 BR Paradise retreat

La Jolla Oasis: Ocean, City and Fire Works Views

New! Beautiful Private Casita- King Bed & Office

Cozy, Quiet and Private Backyard Studio Escape

Casita with private yard and separate entrance

New (2022) North Park Abode w/ Roof Deck

Seaside Sanctuary Studio with Shared Patio and AC!
Guest house rentals with a washing machine and dryer

Beautiful Private Villa walk to beach

Carrie’s North Park Casita, in Heart of San Diego

San Diego Shangri-La

Law Street Retreat

Indoor/Outdoor Sanctuary in Ocean Beach

Rockaway North - Family Friendly, Garage Parking & Laundry

Beautiful Historic Home and Gardens Near Downtown!

Cozy Coop with a View
Quick stats about guesthouse rentals in Mission Bay, San Diego
Total rentals
20 properties
Nightly prices starting at
$203 NZD before taxes and fees
Total number of reviews
2.8K reviews
Rentals with dedicated workspaces
10 properties have a dedicated workspace
Wi-Fi availability
20 properties include access to Wi-Fi
Popular amenities
Kitchen, Wi-Fi and Pool
Destinations to explore
- Rentals with breakfast Mission Bay
- Waterfront rentals Mission Bay
- Rentals with outdoor seating Mission Bay
- Rentals with pools Mission Bay
- Pet-friendly rentals Mission Bay
- Rentals with lake access Mission Bay
- Condo rentals Mission Bay
- Rentals with a fire pit Mission Bay
- Rentals with a fireplace Mission Bay
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- Rentals with a washing machine and dryer Mission Bay
- Apartment rentals Mission Bay
- Beachfront rentals Mission Bay
- Cottage rentals Mission Bay
- Rentals with an EV charger Mission Bay
- House rentals Mission Bay
- Smoking-friendly rentals Mission Bay
- Rentals with beach access Mission Bay
- Rentals with a hot tub Mission Bay
- Rentals with a kayak Mission Bay
- Family-friendly rentals Mission Bay
- Townhouse rentals Mission Bay
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- Beach house rentals Mission Bay
- Hotel rentals Mission Bay
- Rentals with a patio Mission Bay
- Kid-friendly rentals Mission Bay
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- Rosarito Beach
- Oceanside City Beach
- Tijuana Beach
- Torrey Pines State Beach
- Pacific Beach
- Coronado Beach
- San Clemente State Beach
- Coronado Shores Beach
- Oceanside Harbor
- San Onofre Beach
- South Coronado Beach
- Black's Beach
- SeaWorld San Diego
- Windansea Beach
- Trestles Beach
- Surf Beach
- University of California San Diego
- LEGOLAND California
- Balboa Park
- San Diego Zoo Safari Park
- Playas Los Buenos
- Belmont Park
- Pechanga Resort Casino
- Liberty Station