
Guesthouse holiday rentals in Mississippi River
Find and book unique guesthouse rentals on Airbnb
Top-rated Guesthouses in Mississippi River
Guests agree: These guesthouses are highly rated for location, cleanliness and more.

Women of the Woods • Where the Forest Finds You
Step inside and feel the outside disappear. This beautifully curated woodland retreat is tucked into the trees of Bella Vista with a woodsy backyard that opens directly onto the Back 40. Guests consistently remark on attentiveness of hosts, cleanliness, and thoughtful touches. Close enough to everything when you're ready for it, Downtown Bentonville is 20 minutes away. Crystal Bridges, world-class mountain biking, scenic hiking, lakes, shopping, restaurants, and golf are all within easy reach.

The Loft - Mt. Views & Close River Access (0.7)
Created just for two, this cozy haven is the perfect base camp for your outdoor adventures. The Loft features gorgeous mountain views and quick access to the Buffalo River. This 352 square foot modern studio boasts an exceptional outdoor living space. Sit on the porch with your morning coffee before you head out for adventure and keep an eye out for the deer that feel right at home on our 40 acre property. PLEASE SEE the “Other details to note “ section regarding proximity to the main house.

Spacious Country Apartment with Modern Amenities
Welcome to Louisburg! Spacious, private entry, 1000 sq. ft. apartment above detached garage within minutes of wineries, antiques & Cider Mill. Set on 15 acres, and 2 miles down a gravel road, you are out of the city and seeing stars, with an amazing 2nd story view. Sleeps up to 6 with separate bedroom with queen bed and low ceiling (62” great for kids!) loft with 2 twins & a double. All wrapped in unique finishes including an amazing shower! Located only 45 minutes from downtown Kansas City!

Cozy cottage getaway in garden paradise
Get away and relax in a whimsical octagonal cottage surrounded by a lush garden, overlooking a aqua pond and the Wakarusa river. You will have everything you need for a romantic date night or an inspiring place to slow down and reconnect with nature. •1 bedroom open living space with lots of natural light and beautiful views. • Coffee cart with microwave and electric burner and mini frig are provided. • Paddle boat at the lower pond & 2 disc golf nets available for fun. •NO PETS ALLOWED

Private Guest Lake House On 37 Acres In Country
Private guest lake house, located next to main house, on private lake in the country. 2 bedroom, 1 full bath, full kitchen, washer and dryer and large attached screen porch. Private 37 acres of woods and prairie. Fishing and walking trails. Great window views of lake, woods, prairies and river valley. Please note, this guest house is located 1 mile down a county maintained gravel road. 25 minutes from Galesburg, IL, 20 minutes from Monmouth, IL and 35 minutes from Macomb, IL.

Panther Creek Guesthouse
Small farmhouse, private fenced and gated yard, on a tiny farm on a gravel road. Host next door has dwarf goats, chickens, ducks, guineas (1 pair regularly visits/patrols the guesthouse yard), turkeys, a goose, and a couple of LGDs. Horses live across the road and around the curve and up the hill. Eggs and some other basic food items included! Less than 5 miles off Hwy 60 north of Fordland Café, Dollar General, gas in Fordland Springfield 24 Branson 55 7.5 miles from I-44 @ Northview

Turtle Cove- Hot tub, Kayaks, Fire Wood Included
Come and enjoy a peaceful getaway in our quiet cove on Table Rock Lake. Relax in our guest house with a private deck, hot tub, outdoor shower, fire pit and beach at your back door! Enjoy swimming or fishing in the cove, sunning on a paddle board or kayaking at sunset. Paddle boards and kayaks included! Welcome family time relaxing on the hammock listening to the water lapping, barbecuing on the deck or chilling by the fire pit (firewood included). Come rejuvenate in nature's beauty!!

tiny guest house pool 2 bed / Fire-pit
Relax and calm stylish cottage loft place,just a perfect get away , yoga , walk, hiking, enjoy the fire place or swimming pool/watching the birds, beautiful nature breath a flash air , new comfortable bed , recommend for 2 guests, but can sleep up to 5 , there is a king size , a queen size, and a rollaway bed consult with you host, close to shopping stores, gas station, hospitals,culinary institutions school, 25 minutes to Little Rock and hot springs ,not for parties or events

The Penthouse in DTR
Enjoy a stay at the only Luxury apartment rental conveniently located just two blocks from downtown Rogers. The Penthouse in Downtown Rogers is a modern and stylish apartment with all the amenities you need for a short stay or a long retreat: sumptious Sleep Number bed and bedding, gourmet kitchen and outdoor barbecue area, luxe shower and outdoor hot tub with an outdoor fire pit to boot. Just 3 blocks from the Railyard mountain bike park, a short trail to lake Atalanta park.

Relax in Architecture! Secluded, Safe, and Serene.
Welcome to the Falk House! Listed on the National Register of Historic Places by the US Department of the Interior, the Falk House is a treasure of mid-century modern design. We've transformed the original art studio into a stylish, private oasis, with expansive views of nature and Eastover’s Upper Twin Lake. You will be central to all metro destinations, including amazing restaurants, bars, and shopping, as well as area hospitals, courts, and businesses. Long stays ideal.

Tanyard Creek | Waterfall · Bike In/Out
Walk to the waterfall. Ride to the trails. Relax in the trees. Set directly above Tanyard Creek, this private guesthouse offers immediate access to scenic hiking paths and nearby MTB trails—making it the perfect basecamp for both riders and nature-focused stays. Designed for those who want to be outside during the day and fully recharge at night, the space is dialed for comfort with Tempur-Pedic beds and a specialty coffee setup to start your mornings right.

Just off the beaten path
Take it easy at this unique and tranquil getaway. 5 minutes from I-70. Enjoy nature in the woods in our cozy, quiet guesthouse. Close to the University of Missouri for events, medical and business travelers, as well as the Katy Trail for cyclists, wineries, and I-70 for the weary traveler needing a quiet rest and relax. Coffee/tea to wake up enjoying breathtaking views from your private deck.
Popular amenities for Mississippi River guesthouses
Family-Friendly guesthouses

Serene setting w/ private Illinois River access

French Woods Quarters

Country Escape in beautiful Ozarks

Rustic Spring Cabin at Echo Valley Farm

Rustic tool shed stay unique tiny home experience

Sam's Workshop - A Tiny Dreamy Studio

Camp Wandawega: Lakeside 3 Bedroom Cabin

Cozy cabin on farm near Jerseyville and Grafton IL
Guesthouses with a patio

The Rose Cottage w/ Gardens & easy access to Tulsa

Rustic digs on acreage Near Mt Hebron Park, Rogers

Bunkhouse on the Water

Earthen Oasis - Nature Retreat Minutes to Downtown

Charming Hummingbird Cottage

The Hangar

Adorable 1 bedroom guest house

Charming Stone Cottage - Quiet Central Location
Guest house rentals with a washing machine and dryer

Westwood cottage in garden setting

Private guest house

Lafon's Flippin' Cottage

Little House on Broadway

Bayou Long Beard - Bayou view! We greet everyone!

Coffee Cabin

1 of a Kind Guesthouse on 4 Acres. Dogs allowed

Harvest Hill Hideaway
Destinations to explore
- Bungalow rentals Mississippi River
- Train rentals Mississippi River
- Rentals with an accessible height bed Mississippi River
- Hostel rentals Mississippi River
- Boutique hotels Mississippi River
- Family-friendly rentals Mississippi River
- Rentals with a sauna Mississippi River
- Ski-in/ski-out rentals Mississippi River
- Holiday home rentals Mississippi River
- Boat rentals Mississippi River
- Ranch rentals Mississippi River
- Private suite rentals Mississippi River
- Rentals with lake access Mississippi River
- Serviced apartment rentals Mississippi River
- Rentals with beach access Mississippi River
- Loft rentals Mississippi River
- RV rentals Mississippi River
- Tree house rentals Mississippi River
- Tent rentals Mississippi River
- Beachfront rentals Mississippi River
- House rentals Mississippi River
- Apartment rentals Mississippi River
- Resort rentals Mississippi River
- Cabin rentals Mississippi River
- Rentals with a soaking tub Mississippi River
- Earth house rentals Mississippi River
- Rentals with an accessible height toilet Mississippi River
- Luxury rentals Mississippi River
- Rentals with breakfast Mississippi River
- Condo rentals Mississippi River
- Tiny house rentals Mississippi River
- Campsite rentals Mississippi River
- Yurt rentals Mississippi River
- Hotel rooms Mississippi River
- Shipping container rentals Mississippi River
- Pet-friendly rentals Mississippi River
- Dome rentals Mississippi River
- Farmstay rentals Mississippi River
- Aparthotel rentals Mississippi River
- Rentals with pools Mississippi River
- Nature eco lodge rentals Mississippi River
- Bed and breakfasts Mississippi River
- Cottage rentals Mississippi River
- Chalet rentals Mississippi River
- Houseboat rentals Mississippi River
- Villa rentals Mississippi River
- Rentals with a hot tub Mississippi River
- Barn rentals Mississippi River
- Waterfront rentals Mississippi River
- Rentals with a kayak Mississippi River
- Castle rentals Mississippi River
- Townhouse rentals Mississippi River
- Guesthouse rentals United States
- Things to do Mississippi River
- Landmarks Mississippi River
- Food tours Mississippi River
- Wildlife Mississippi River
- Art workshops Mississippi River
- Cultural tours Mississippi River
- Outdoors Mississippi River
- Things to do United States
- Shopping and fashion United States
- Dining United States
- Museums United States
- Cultural tours United States
- Architecture United States
- Workouts United States
- Art workshops United States
- Flying United States
- Wellness United States
- Food tours United States
- Wildlife United States
- Landmarks United States
- Water sports United States
- Performances United States
- Tastings United States
- Galleries United States
- Cooking United States
- Beauty United States
- Outdoors United States





