
House holiday rentals in San Luis Obispo
Find and book unique houses on Airbnb
Quick stats about house rentals in San Luis Obispo

Total holiday rentals
Explore 190 holiday rentals in San Luis Obispo

Verified guest reviews
Over 15,610 verified reviews to help you choose

Family-friendly holiday rentals
120 properties offer extra space and kid-friendly amenities

Pet-friendly accommodation
Find 60 rentals that welcome pets

Rentals with dedicated workspaces
90 properties have a dedicated workspace

Wi-Fi availability
190 of San Luis Obispo holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across San Luis Obispo rentals

4.9 Average rating
San Luis Obispo stays are highly rated by guests—averaging 4.9 out of 5!
Top-rated house rentals in San Luis Obispo
Guests agree: These houses are highly rated for location, cleanliness and more.

The Los Osos Valley Guest House
Settle into authentic 'SLO CAL' in our cozy and casual Surf Ranchita - The Los Osos Valley Guest House is a rustic hideaway nestled between quaint rural farmlands, laid back Los Osos and the rugged natural coastline. It's a perfect base stay with it's casual rustic vibe, unique character and renovated modern conveniences. Enjoy a fully stocked 3 bedroom house with hot tub, infrared sauna, outdoor shower, 4 TVs private WiFi, heated marble floors, BBQ patio and outdoor seating with amazing views.

The Quailhouse on Ranch near Avila Beach
The Quailhouse is located on a gated, rural working Ranch in Avila Valley - San Luis Obispo. Avila Beach and downtown San Luis Obispo are just a 7 minute drive away. You are centrally located for enjoying the Central Coast, while being privately tucked away in nature from the hustle and bustle. Nearby are hiking/biking trails, beaches, wineries and restaurants. Enjoy a distinctive experience that includes locally sourced, environmentally friendly amenities while relaxing in a serene setting.

New 1 Bedroom House - Great Location in SLO
This is a brand new 1 bedroom house attached to the back of the main house but with a completely separate entrance and is a fully separate unit, think duplex. It is located less than a mile from Cal Poly campus, less than 2 miles from downtown SLO, and is a short drive to local beaches. The deck is tucked next to a beautiful oak tree and is very private setting. Bishops Peak mountain is less than a mile away for a great hike and it also blocks a lot of wind for a warmer experience in SLO.

1884 Elegant Home: Fire Pit, Tesla Tech, Near DT
Step into history at this charming 2-bedroom railroad house in downtown SLO. Enjoy its preserved heritage, from the 11-foot tall ceilings to the spacious kitchen. Sleep luxuriously on Purple mattresses in both bedrooms. Unwind next to the fire pit in the backyard. It's a short 7 min. stroll to downtown & next to 5 restaurants including Sally Lou's coffee shop & the train station. Experience SLO's charm like never before with this perfect location home. Send us a message to plan your trip!

Cozy Studio Close to Downtown SLO
Cozy Studio is located in a quiet residential neighbor with secure off street parking. Whether you choose to relax in my comfortably furnished studio or enjoy the private outdoor patio, my home will provide a serene retreat. From the house, it is a ten minute walk to downtown. Home features smart tv with Netflix, Hulu, and Sling. It also features high-speed wifi and air conditioning. Please note that the bedroom is upstairs and the bathroom is downstairs . Home Stay Permit # 0235-2020

San Luis Obispo Wine Country Retreat
Escape to a charming three-bedroom farmhouse on a shared 10-acre ranch in San Luis Obispo's Edna Valley. Newly renovated with modern amenities including a spacious kitchen, cozy living room with smart TV, and private patio with fire pit. Sleeps up to six guests with stunning views of rolling hills. AC, heating, WiFi, and BBQ grill included. Explore nearby wineries and restaurants or relax on the private patio. Long term stays allowed. Book now for a memorable California getaway.

Serenity On Serrano
Serenity on Serrano is a Frank Lloyd Wright-inspired peaceful haven set in one of SLO's most prestigious neighborhoods right on the edge of a creek. This midcentury modern home is just steps to hiking, the downtown, shopping, and restaurants. Be prepared for nature as it's common to be greeted by wild turkeys, birds, and more. Enjoy the tranquility of minimalist design. Note: There is $25 per night for each extra guest over 4. Permit # H-0408-2023

SLO Vibes
Enjoy a stylish experience at this centrally-located place with a contemporary design and panoramic hillside views. Modern all-electric home featuring 2 bedrooms and 2.5 bathrooms is ideally located just minutes from Downtown San Luis Obispo and Edna Valley Wine Country. Step into a modern kitchen, and private balcony off the heart of your living space. Both bedrooms have ensuite bathrooms. 2-car garage. Hope you soak in this vibrant home!

Cozy Retreat Walking Distance to Downtown
This historic home has been recently remodeled. It sits in a quiet, friendly neighborhood which is walking distance to downtown. The second bedroom overlooks a large, beautiful garden and you can hear the gentle song of frogs at night and church bells in the morning. All beds feature luxury linens and the Wifi is fantastic! Forget your worries in this spacious and serene space. Walking distance to High Street Deli and Village Host Pizza.

The Downtown House SLO with Private Parking
Charming 1920s bungalow in the heart of downtown San Luis Obispo! Walk to top restaurants, coffee shops, parks, and the famous Farmers Market. Perfect for SLO Marathon runners—just a mile from the starting line. Original details + modern upgrades, A/C, full kitchen, laundry, and parking. Ideal for guests who love vibrant, walkable neighborhoods. We’re locals and happy to share our favorite hikes, wineries, and spots to explore!

Mid Century Modern Loft Downtown SLO
This unique place has a style all it's own. Mid century modern loft located just a few blocks from downtown SLO. 10 min walk and 3 min drive to all the great shops and restaurants SLO has to offer. Thick glass walls in the bedroom allow for an open loft like experience. Many fun details throughout the place create a truly unique vibe. This 800sf loft located upstairs above a salon is private and has designed parking.

Modern Cayucos Bungalow - Ocean Views and Hot Tub
Welcome to our modern and chic Cayucos surf shack! Perched upon the hillsides of southern Cayucos, enjoy sweeping ocean views of Estero Bay, from the front balcony while sitting next to the outdoor gas fire pit, or from the secluded back patio while soaking in your very own private hot tub! This cottage includes a spacious backyard for your pup to roam that backs up to hundreds of acres of nature and open space.
Popular amenities for San Luis Obispo house rentals
House rentals with a pool

Luxe Wine Country Stay, Pool, Firepit | Devi Ranch

PaSO PaNORAMA-Swimming Pool, Hot Tub, & Views

Spacious SLO CAL Home w/ Pool, Spa. Pet Friendly!

Mountain Sanctuary, Saltwater Pool

Getaway at the Highlands+Heated Pool+Hot Tub

Luxury Mountain View Retreat Pool/jacuzzi

Historic 1895 Edna Railhouse with Heated Pool

Historic House near Paso Robles, Pool & Hot Tub
Weekly house rentals

Mid-century home in the heart of Arroyo Grande.

STENNER CREEK RANCH

Family Home Close to Downtown

Central Coast - Creekside Living

Blue Wave of Avila

Downtown Craftsman with Courtyard

Back Bay Getaway - Dog Friendly - Home in Los Osos

Boutique Bungalow, San Luis Obispo
Private house rentals
Place Among the Trees: walk to downtown SLO

The Farm House,Paso Robles| Firepit| Pet Friendly

Upscale. Pet friendly. Great location! 6-10 guests

Downtown | Hottub | Sleeps 6

2735 Nokomis

Central Coast Casa

Bishops Peak Retreat-Spa, Family Friendly!

Cozy, Clean and Close to downtown SLO!
When is the best time to visit San Luis Obispo?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sept | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | $396 NZD | $387 NZD | $364 NZD | $422 NZD | $399 NZD | $495 NZD | $470 NZD | $439 NZD | $402 NZD | $406 NZD | $430 NZD | $385 NZD |
| Avg. temp | 12°C | 12°C | 13°C | 14°C | 15°C | 16°C | 18°C | 18°C | 18°C | 17°C | 14°C | 11°C |
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- Cayucos Beach
- Moonstone Beach
- Pismo State Beach
- Montaña de Oro State Park
- Hearst Castle
- Morro Strand State Beach
- Cayucos State Beach
- Los Padres National Forest
- Morro Rock Beach
- Morro Bay Golf Course
- California Polytechnic State University
- Oceano Dunes State Vehicular Recreation Area
- Mission San Luis Obispo de Tolosa
- Pismo Preserve
- Charles Paddock Zoo
- Dinosaur Caves Park
- Sensorio
- Monarch Butterfly Grove
- Vina Robles Amphitheatre
- JUSTIN Vineyards & Winery
- Tablas Creek Vineyard
- Elephant Seal Vista Point
- Downtown City Park
- Niner Wine Estates
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