
House holiday rentals in La Mesa
Find and book unique houses on Airbnb
Quick stats about house rentals in La Mesa

Total holiday rentals
Explore 320 holiday rentals in La Mesa

Nightly prices starting at
La Mesa holiday rentals start at $52 NZD per night before taxes and fees

Verified guest reviews
Over 14,030 verified reviews to help you choose

Family-friendly holiday rentals
210 properties offer extra space and kid-friendly amenities

Pet-friendly accommodation
Find 110 rentals that welcome pets

Holiday rentals with a pool
80 properties feature pools

Rentals with dedicated workspaces
190 properties have a dedicated workspace

Wi-Fi availability
320 of La Mesa holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across La Mesa rentals

4.9 Average rating
La Mesa stays are highly rated by guests—averaging 4.9 out of 5!
Top-rated house rentals in La Mesa
Guests agree: These houses are highly rated for location, cleanliness and more.

Family Fun! Game Garage + Big Yard + Free Parking
Embodying the epitome of cool! This home has the perfect blend of a vintage feel with a modern touch. Stepping inside, you’re greeted by an atmosphere of fun & creativity. A large private serene retreat in the backyard w/abundant seating and fire pit. Huge 3-car garage bonus space with games. Located just minutes from downtown La Mesa, many dining options & conveniences. Everything you need & more! Distance to: San Diego Zoo: 18 min Sea World: 23 min SDSU: 13 min Airport: 19 min Gaslamp: 18 min

Family Pool Retreat + Gym, Fire Pits, Views (Sleep
Find your family's dream spot in San Diego! Our cozy house sits on a quiet hill, offering privacy and amazing sunset views. Dive into our pool year-round (heating at an additional cost), roast marshmallows by the fire, and cook up fun meals together. With 3 bedrooms and 2 bathrooms, it’s perfect for families, accommodating up to 9 guests. Plus, we're close to all the best attractions. Want a vacation you'll always remember? Send us a message to make it happen! 🌅🏠 We have 3 comfy beds that can

2 Bed Hidden Oasis | Garden, Laundry, Parking
Capture the essence of San Diego in our Hidden King Suite with Garden hosted by Ethos Vacation Homes. The peaceful property features elite comfort for up to 4 guests with beautiful outdoors and garden, off-street parking, A/C and heating, FREE laundry, comfortable king and queen size beds, plenty of sheets and towels, a large HDTV, Netflix, Max, Hulu, Showtime, Disney+, Apple+, and ESPN+. This spacious San Diego vacation rental home has everything you need for your California Dreaming Vacation!

Sunnyside Resort Spa, Beach, Zoo, Arcade
SEND US A MESSAGE FOR SPECIAL OFFER! Imagine booking the most memorable experience with your party! Kick back and relax in a safe, stylish casita. Check in contactless and enjoy! Cozy, comfy, and a perfect base for exploring the city. Cook your own meal in the alluring kitchen or enjoy your meal at the cute dining area outside. Great for family's or trips with friends! The entire guest house is is 5 minutes from SDSU, 15 minutes from the beach and 15 minutes from downtown San Diego! Enjoy

Classic Mid-Century Mount Helix Home with Views
Located in the exclusive Mount Helix neighborhood of La Mesa, this property is conveniently located near the 8 and 94 freeways for easy access to explore the greater San Diego area. Attractions like the historic Balboa Park with the San Diego Zoo or Sea World are a 15-25 minute drive away. With spacious interior and exterior spaces at the property, though, you may not want to leave. The property includes 4 bedrooms and 2.5 bathrooms with furnished living room, family room and kitchen.

Cottage in the Garden! New! Modern!
COTTAGE IN THE GARDEN - New! Modern! Find beauty and serenity in this special guest house in one of San Diego's most desirable areas! Flowering bushes, plants, olive tree and fruit trees seen from all windows. All amenities: WiFi, Cable, serving dishes and tableware, full coffee bar, Ninja Blender, Flat screen TVs, 100% Egyptian Cotton Sheets or Boll and Branch Sheets (used by 3 Presidents), Japanese Toilette and more. 15 minutes to Downtown San Diego and 20 minutes to the beach!

Zen Retreat: 3-Bedroom Oasis near La Mesa Village
Relax in this charming 3-bedroom, 1-bathroom home located just 1 mile from the heart of Historic Downtown La Mesa Village. Nestled in a quiet, central neighborhood, this cozy retreat offers easy access to major freeways, top-rated restaurants, and the local trolley line making it a breeze to explore the best of San Diego. Within 10 to 15 miles, you’ll find yourself in iconic destinations like Downtown San Diego, Balboa Park, Coronado Island, scenic beaches, and beautiful mountain trails.

San Diego Oasis: Private Pool & Sunny Escape!
¡Bienvenidos a nuestro retiro en La Mesa! 🌟 Nos apasiona compartir la magia de este lugar con nuestros huéspedes. Disfruta de la comodidad y conveniencia en esta casa de 2 recámaras y 2 baños, meticulosamente remodelada para ti. ✨ Prepara tu traje de baño, tus bolsas de compras y tu espíritu aventurero para vivir lo mejor de la zona desde nuestro acogedor hogar. 🏡 ¡Tu escapada perfecta comienza aquí! 🌴🛍️ Reservar con nosotros es vivir una experiencia inolvidable. 🥂✨

Mountain View• Solar-heated Pool •HotTub •GameRoom
☀️Welcome to our fun, newly updated home in a quiet, secure neighborhood in La Mesa ☀️ 🌊Swim in our beautiful blue, solar-heated pool while enjoying an elevated mountain view, perfect for relaxation and fun. Unwind in our fantastic game room, equipped with a pool table, arcade machines and pop-a-hoop, offering endless entertainment for guest at all age. End the day in our in-home movie theater, where you can enjoy your favorite films in ultimate comfort. ☀️

Palm Cottage, San Diego
Palm Cottage sits in the heart of La Mesa Village, San Diego. Enjoy the charm of a historic home with a fully remodeled and stylish interior featuring both Dutch & French doors letting in plenty of sunshine. A large private yard w/ covered outdoor living area creates the ultimate indoor/outdoor lifestyle. You're steps from the local grocery store, village shopping, coffee shops, restaurants, bars and the trolley. You could not ask for a better location!

Spacious & Fun | 5br, 4.5ba | Hot Tub | Views
Experience sunny San Diego from this 5 bedroom, 4.5 bathroom foothill home. Wake up to panoramic views of the surrounding hillsides and gather in the spacious living and dining rooms. The home is conveniently located just 15-20 minutes from San Diego's famous beaches and top attractions. After a day of exploration, unwind in the backyard area featuring a hot tub, fire pit, pool table, and life-sized chessboard.

Sunny & Spacious 3BR Retreat w/ Parking & A/C
Discover your La Mesa retreat! This newly refurbished home offers a perfect blend of comfort and convenience. Enjoy a gourmet kitchen, stylish dining, three bedrooms, two modern bathrooms, and an expansive yard. Explore nearby attractions like the Grossman Center (10-min walk) with shopping and dining, or venture to San Diego's heart (20-min drive). Perfect for families and groups seeking a relaxing getaway.
Popular amenities for La Mesa house rentals
House rentals with a pool

La Jolla Beach House-Family Focused-3min to Beach

Entertainers Dream Pool Home

San Diego Pool | Fire Pit | Sunshine | Sleeps 10

Bright and spacious home with views, pool & spa.

Designer Luxury Rental With Pool

ModernCoastal I View I Pool ITub

Luxe Home w. Serene Backyard Spa

Modern Hilltop Home: Roomy, Views, Family-Friendly
Weekly house rentals

Tiny Home with a View

[1,888 SF] Casa De Rosas: Spacious home near SDSU

Airbnb Luxe: Pool, View, Office and Fitness

HotTub & 100+ Game Arcade Family Getaway San Diego

Techie Family Stay | Heart of San Diego

Downtown La Mesa gem

Luxury Hilltop Getaway • Scenic Views

Modern La Mesa Home | 2BR • 2BA • Prime Location
Private house rentals

5br Home with Pool, Hot Tub, BBQ, Putting green

Sunset Summit by Coastline Vacation Rentals

Newly Updated & Beautiful Home 5 bedrooms • 5 beds

San Diego Retreat ·Jacuzzi + Billiards +Sleeps 12!

La Mesa Retreat | Hot Tub | Fire Pit | Longer stay

Hot Tub, BBQ, Patio, 4 min SDSU, Central San Diego

Hilltop Family Retreat | Heated Pool & Ocean Views

Mid-Century 4BR Oasis w/Pool & Hot Tub, San Diego
When is the best time to visit La Mesa?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sept | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | $319 NZD | $338 NZD | $369 NZD | $310 NZD | $317 NZD | $369 NZD | $431 NZD | $363 NZD | $319 NZD | $324 NZD | $338 NZD | $343 NZD |
| Avg. temp | 15°C | 15°C | 16°C | 17°C | 18°C | 20°C | 21°C | 22°C | 22°C | 20°C | 17°C | 14°C |
Destinations to explore
- Southern California Holiday rentals
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- Rentals with a patio La Mesa
- Guesthouse rentals La Mesa
- Rentals with breakfast La Mesa
- Apartment rentals La Mesa
- Smoking-friendly rentals La Mesa
- Rentals with pools La Mesa
- Fitness-friendly rentals La Mesa
- Private suite rentals La Mesa
- Pet-friendly rentals La Mesa
- Rentals with a fire pit La Mesa
- Rentals with outdoor seating La Mesa
- Rentals with a fireplace La Mesa
- Family-friendly rentals La Mesa
- Villa rentals La Mesa
- Rentals with a washing machine and dryer La Mesa
- Rentals with a hot tub La Mesa
- Rentals with an EV charger La Mesa
- Rentals with beach access La Mesa
- House rentals San Diego County
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- House rentals United States
- Rosarito Beach
- San Diego Convention Center E Ent
- SeaWorld San Diego
- Petco Park
- University of California-San Diego
- Oceanside City Beach
- San Diego Zoo Safari Park
- Ocean Front Walk
- Pacific Beach
- San Diego Zoo
- Coronado Beach
- Torrey Pines State Beach
- Tijuana Beach
- Balboa Park
- Pechanga Resort Casino
- San Diego State University
- LEGOLAND California
- Mission Beach
- La Misión Beach
- Anza-Borrego Desert State Park
- Moonlight State Beach
- Liberty Station
- Oceanside Harbor
- Sesame Place San Diego





