
House holiday rentals in La Mesa
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Top-rated house rentals in La Mesa
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Popular amenities for La Mesa house rentals
House rentals with a pool

3 BR Urban Oasis with Pool and Spa in Great Area
I am a San Diego local, but my family was coming to town and we needed more space. I picked this place because I knew my sister and brother-in-law would love being able to walk to all the restaurants and brewery nearby and my 6 year old nephew would get a lot of use out of the pool. The place exceeded my expectations, it was perfect for everyone. We spent a lot of time in the backyard swimming or playing board games, and my Mom got a lot of use out of the hot tub. Communication with the host was excellent and the place was comfortable and clean. The only downside is my family might visit too often now!

La Jolla Beach House-Family Focused-3min to Beach
Our host John provides a beautifully decorated home in a quiet, central neighborhood. The setup is exceptional, with both a heated pool and hot tub, and the experience felt like staying in a boutique hotel. He thoughtfully includes amenities like toothbrushes, makeup remover wipes, cotton pads, and more — the attention to detail really impressed us. We absolutely loved our time in La Jolla, and John’s local tips were spot-on. We’ll definitely be returning and highly recommend booking with him.

Bright and spacious home with views, pool & spa.
We had an incredible stay at Miguel’s Airbnb! The highlight was definitely the pool – it was sparkling clean and well-maintained. Everything was exactly as described, and Miguel was a fantastic host, ensuring we had everything we needed for a perfect stay. Highly recommend this place to anyone looking for a relaxing, private and hassle-free getaway!

Stunning San Diego Home w/Pool,Spa,Outdoor Oasis
We loved our stay, Bruce was so friendly and very accommodating. We had quite a large group stay there, 2 of my kiddos included- Bruce had a little bucket of toys to play with for them which was such a nice surprise. The house was clean and everything in working order. While we were there, most of our time was spent outside in the beautiful backyard where there was such a great vibe! We’d for sure stay here again next time we’re in San Diego!

University Heights Oasis Getaway
Exactly as the other reviewers have described, it is just a beautiful oasis in a perfect quiet neighborhood. Don’t wait, book now!

Oasis with ocean views/Pool/Hot tub! Sleeps 10!
We have stayed in many different types of homes both good and bad. But, I’ve gotta say “This one has been BY FAR, THE BEST”!! The view as well as the house is absolutely amazing. The design of the home is gorgeous. The house was extremely clean and the beds were very comfortable. I must mention the squatty potties and bidet’s in the bathrooms… SUPERB!! Before booking my reservation, I asked Van if I could have my family and friends (about 10 people) come over after a graduation ceremony and he said yes. He even accommodated us with extra tables and chairs. My friends and family all loved the place. Van always replied to my messages no matter the time of day or night. There was a hiccup with the fire alarms in the house which was completely out of Van’s control, but he handled it well. He personally appeared to resolve the issue. Meeting Van in person did not disappoint. He is as nice in person as he is in messages. We are definitely going to come back.

5BR | Salt Water Pool | Hot Tub | Fire Pit| BBQ
The place was clean and well-kept. The 5 rooms had comfortable beds and individual A/C units, adding to the comfort. The backyard was great for hosting. The only minor criticism was the lack of instructions for the fire pit. I managed to turn it on successfully; it produced a strong fire, perfect for cozy nights. There was adequate seating for everyone. Inside, the house felt clean, including the bathrooms. The living room had a large couch and the dining area had a large table, accommodating our group's size. A small improvement would be to hang the towels in the bathrooms to avoid a scavenger hunt. The wifi was down upon arrival and never regained function despite troubleshooting, but my cellular service (T-mobile) was sufficient. The host was very communicative and responsive throughout my stay. I didn’t receive dining recommendations, but it was easy to find places to eat.

Entire Home Retreat* Private Pool & Hot Tub
If you have a family with children this is the PERFECT place! Not only are there plenty of toys and board games to keep the kids entertained, there is also a pool and jacuzzi. This rental even had toothbrushes and toothpaste along with sunscreen and aloe in case you forgot.
Weekly house rentals

Escape to tranquility: the perfect retreat
This was my first experience in an Airbnb and I could not have been more pleased. This home is clean, comfortable, and had everything I needed for a week-long stay! Some of the many highlights: Parking is dedicated and convenient. Kitchen well stocked with a full-sized fridge. There is so much room between the kitchen, living/bedroom and the bathroom/bathroom area! Recliners and bed were super comfortable. TV was easy to use and seemed to have a ton of channels, plus apps like YouTube. Water pressure in the shower was *fantastic* (also the shower head situated high on the wall, great for tall guests). Fast internet connection. Quiet neighborhood. I kept the windows and door open all day while I was there. Lovely patio with a table and large umbrella. Very nice and communicative owners! Most importantly, I felt very safe as a solo traveler. I feel lucky I had the opportunity to stay here and would 100% do so again!

Cozy, cute home: Welcome to Hilltop Sanctuary
Sarah’s place was clean and comfortable. Easy check in. Host was on top of everything which made it smooth. Definitely worth the money spent. Highly recommended!!!

Exquisite, Modern, Walk to Bliss
Perfect! Derek and Brooke really have such a wonderful place and it’s so close to a very eventful downtown La Mesa. We dined there each night and attended the local Farmer’s markets. The home is so peaceful and had everything we needed. It’s just enough space for 2 - 4 people. (This trip was only me and my mom) They gave ample instructions and it was very easy to lock up when we left and easy to enter. We also appreciated being able to park directly in front of the unit on the street. The neighborhood is so lovely, you’ll wish you lived on this street! I’m definitely going to rebook this space next time I’m in town.

The Pool House
The place was really nice, and the owners were very easy to work with. The place was really nice, and the owners were very easy to work with. We felt very comfortable in the home. There were a few small issues — when we moved the sofa bed, we found quite a bit of trash underneath, as well as under other furniture and behind trash cans. I have small children and wanted to make sure nothing was left behind, so it was noticeable during our quick check. Other than that, everything was peWe felt very comfortable in the home. There were a few small issues — when we moved the sofa bed, we found quite a bit of trash underneath, as well as under other furniture and behind trash cans. I have small children and wanted to make sure nothing was left behind, so it was noticeable during our quick check. Other than that, everything was perfect! I would absolutely love to reserve this Airbnb again on our next visit to San Diego. We’re originally from San Diego and travel back often to visit family.

Lavish pool Villa In Mt. Helix, close to beaches
We stayed at Zeina and Mo's place for one week with our East Coast and West Coast children and grands--6 adults and 6 children in all from ages 2-12. We could not have been more pleased. The house was meticulously clean and was spacious enough for all. The kitchen was well stocked with all we needed to prepare meals at home. An added plus was an outdoor grill under a cabana like space with a table for 6 and outdoor counter to provide additional seating. The pool is larger than it appears in the pictures on the web site. The whole outdoor space was clean and welcoming and proved to be a center piece of our stay. There were plentiful and soft towels for bathing and the pool. Zeina and Mo were promptly responsive to any questions or concerns we had. We left with many fond memories of our week together, in large part due to to how comfortable and pleasant we felt about our stay was at Zeina and Mo's house.

Modern, Private, & Stylish Home
Great place, very easy to navigate to! House is very spacious and beautiful! Longevity Living ensured we were satisfied from start to finish!

Cozy Getaway | SDSU | Firepit & Private Yard
We were in San Diego for medical appointments for my wife, and this was a peaceful oasis. Very clean and quiet. Great value for the price.

Charming Cozy Studio Centrally Located
I loved staying here. The space was cozy and very clean. Nina was immensely responsive when I had a question. I felt very safe here as a solo traveler.
Private house rentals

[1,888 SF] Casa De Rosas: Spacious home near SDSU
this house was very nice and peaceful i would book again Thank you

Welcome New & Improved! Your Home Away from Home
The place itself was clean, stylish, and had all the amenities we needed for a comfortable stay. The parking was really nice to have. The host was incredibly responsive and helpful, making sure we had everything we needed. It’s clear they take great pride in their property. We felt right at home from the moment we walked in. We recommend it to anyone looking for a nice place to stay. We look forward to booking it again on our next visit!

Cozy 1BR Home with Lovely Front Yard
This place is so cute! It was close to everything AC works great. The bed was super comfy and the massage chair was a huge bonus! Will be going back if available next time I’m in town! Ty

Sunny Loft | Beaches | Lakes | Trails
The host welcomed us with a sign, I enjoyed the night there. I’m a small petite person so I slept on the coach and it’s so comfortable. I recommend for anyone who doesn’t mind a small setting. My siblings and I felt safe and secured during our stay! I recommend!

SDSU/Downtown <10 Min | Pet Friendly | Game Room
Thank you guys for having us , beyond a 5 star stay here … beautiful neighborhood and the ambience in the home is extremely beautiful , will recommend to others.

Mountain Top 4 Bdrm Home with Spectacular Views!
I had an incredible stay and can’t say enough great things about this place and our host! The home was spotless, exactly as described, and even more beautiful in person. Every detail was thoughtfully prepared, from the cozy bedding to the well-stocked kitchen. It truly felt like a home away from home. Our host was communicative, kind, and made the entire process smooth from start to finish. Check-in was easy, and they went above and beyond to ensure we had everything we needed. You can tell they really care about their guests’ experience. I would absolutely stay here again and highly recommend it to anyone looking for a relaxing, comfortable, and stress-free stay. Thank you for everything!

SunnySD Private Pool-SoCal Oasis
Kaios place was perfect for our event. Not a thing I would change about this place. Great donut shops, coffee spots, ceviche spots as stones throw away. Peaceful, quiet, stress free place.

Hilltop luxe retreat with breathtaking views
Lovely home and view. Everything as described!
Quick stats about house rentals in La Mesa
Total rentals
290 properties
Total number of reviews
12K reviews
Family-friendly rentals
180 properties are a good fit for families
Pet-friendly rentals
90 properties allow pets
Rentals with a pool
70 properties have a pool
Rentals with dedicated workspaces
170 properties have a dedicated workspace
Destinations to explore
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- Rosarito Beach
- Oceanside City Beach
- Torrey Pines State Beach
- Tijuana Beach
- Pacific Beach
- Coronado Beach
- La Misión Beach
- SeaWorld San Diego
- Coronado Shores Beach
- Oceanside Harbor
- University of California San Diego
- LEGOLAND California
- Black's Beach
- San Diego Zoo Safari Park
- Balboa Park
- Belmont Park
- Pechanga Resort Casino
- Liberty Station
- Moonlight Beach
- Sesame Place San Diego
- Playas Los Buenos
- Playa Popotla
- USS Midway Museum
- Torrey Pines Golf Course