House holiday rentals in La Mesa

4.91 out of 5 average rating, 115 reviews

HotTub & 100+ Game Arcade Family Getaway San Diego

Nearby📍 ✈️ San Diego Airport - 20min drive 🦓 San Diego Zoo – 17 min drive 🌸 Balboa Park – 17 min drive 🐬 SeaWorld – 22 min drive 🏙 Gaslamp Quarter – 20 min drive 🏡 Old Town San Diego – 20 min drive 🏖 Mission Beach – 25 min drive ⚾ Petco Park – 20 min drive 🌄 Mount Helix Park (scenic views) – 8 min drive ☕ Best Coffee: Public Square Coffee House (5 min) 🧭 Best Family Activity: San Diego Zoo (17 min) 🛍 Best Shopping: Grossmont Center (5 min) 🌿 Best Nature Spot: Mount Helix Park (8 min)

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An outdoor seating area is equipped with sectional sofas arranged around a fire pit, featuring a grassy lawn surrounded by lush greenery. A large tree provides shade, while a spacious porch is visible in the background, contributing to the serene atmosphere.

4.94 out of 5 average rating, 158 reviews

Family Fun! Game Garage + Big Yard + Free Parking

Embodying the epitome of cool! This home has the perfect blend of a vintage feel with a modern touch. Stepping inside, you’re greeted by an atmosphere of fun & creativity. A large private serene retreat in the backyard w/abundant seating and fire pit. Huge 3-car garage bonus space with games. Located just minutes from downtown La Mesa, many dining options & conveniences. Everything you need & more! Distance to: San Diego Zoo: 18 min Sea World: 23 min SDSU: 13 min Airport: 19 min Gaslamp: 18 min

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The interior of the studio showcases a spacious layout, featuring a king size bed adorned with yellow and white pillows. A dark gray sofa complements the decor, facing a coffee table with a plant. Large glass doors provide a view of the garden and outdoor seating.

4.9 out of 5 average rating, 310 reviews

2 Bed Hidden Oasis | Garden, Laundry, Parking

Capture the essence of San Diego in our Hidden King Suite with Garden hosted by Ethos Vacation Homes. The peaceful property features elite comfort for up to 4 guests with beautiful outdoors and garden, off-street parking, A/C and heating, FREE laundry, comfortable king and queen size beds, plenty of sheets and towels, a large HDTV, Netflix, Max, Hulu, Showtime, Disney+, Apple+, and ESPN+. This spacious San Diego vacation rental home has everything you need for your California Dreaming Vacation!

ValueFamilyIndoor spaces

A contemporary casita is featured with a neatly landscaped front yard and stone pathway leading to the entrance. A garage is visible to the left, and large windows allow natural light to illuminate the welcoming exterior, which is surrounded by lush greenery.

4.91 out of 5 average rating, 137 reviews

Sunnyside Resort Spa, Beach, Zoo, Arcade

SEND US A MESSAGE FOR SPECIAL OFFER! Imagine booking the most memorable experience with your party! Kick back and relax in a safe, stylish casita. Check in contactless and enjoy! Cozy, comfy, and a perfect base for exploring the city. Cook your own meal in the alluring kitchen or enjoy your meal at the cute dining area outside. Great for family's or trips with friends! The entire guest house is is 5 minutes from SDSU, 15 minutes from the beach and 15 minutes from downtown San Diego! Enjoy

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4.83 out of 5 average rating, 127 reviews

Large Home Heated Pool Spa | Game Room (Sleeps 30)

Gather your friends and family for the ultimate getaway at this spacious paradise! Featuring a sparkling pool, soothing spa, BBQ pit, and cozy fire pit, there’s endless fun for everyone. The game room is packed with entertainment options, perfect for some friendly competition or unwinding after a day in the sun. Designed to host large groups comfortably, this home is ideal for reunions, celebrations, or just a relaxing escape! This home offers everything you need for an unforgettable stay!

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A view into a modern living space reveals a sleek kitchen with bar seating and a spacious dining area. Natural light floods the room through large glass doors, showcasing lush greenery outside. A cozy area is completed with a colorful rug beneath and a inviting seating arrangement.

4.93 out of 5 average rating, 245 reviews

Cottage in the Garden! New! Modern!

COTTAGE IN THE GARDEN - New! Modern! Find beauty and serenity in this special guest house in one of San Diego's most desirable areas! Flowering bushes, plants, olive tree and fruit trees seen from all windows. All amenities: WiFi, Cable, serving dishes and tableware, full coffee bar, Ninja Blender, Flat screen TVs, 100% Egyptian Cotton Sheets or Boll and Branch Sheets (used by 3 Presidents), Japanese Toilette and more. 15 minutes to Downtown San Diego and 20 minutes to the beach!

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A colorful studio space features turquoise walls and a ceiling fan. A comfortable sofa with decorative pillows is paired with a coffee table. A bed with a floral-patterned comforter sits against a window, while a TV and white refrigerator complete the modern setup.

4.99 out of 5 average rating, 348 reviews

SDCannaBnB #2 *420 *parking *dog-friendly *hot tub

Welcome to SDCannaBnB - San Diego's premier cannabis-friendly rental! Our studio is newly remodeled with luxury ammenities. We proudly cater to the cannabis community and non-users alike. Our studio has HEPA air purifiers, is fully ventilated and receives deep cleanings between each guest. This ensures that every guest checks into a clean, fresh-smelling place that feels like home. Our studio is located in our quiet, fully fenced in backyard, close to San Diego's attractions

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A spacious outdoor area features a swimming pool, accompanied by colorful lounge chairs and a large umbrella for shade. A unicorn float is visible in the water, with potted flowers adding a touch of vibrancy. The home's façade offers multiple windows and seating options nearby.

4.99 out of 5 average rating, 201 reviews

Mid-Century Style Family House with Spa

This home is the epitome of 1950’s luxury. A perfect family oasis, you won’t even want to leave the property. Beautiful Mt. Helix mid-century modern family home with incredible views, designed by architect of original Las Vegas Desert Inn situated on nearly an acre. Less than 20 minute drive to beaches/Zoo/Sea World/Downtown. With a swimming pool, jacuzzi, and AC. Surrounded by orange, lemon, pomegranate trees and herb garden. No loud parties please, this is a quiet community.

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4.94 out of 5 average rating, 147 reviews

Palm Cottage, San Diego

Palm Cottage sits in the heart of La Mesa Village, San Diego. Enjoy the charm of a historic home with a fully remodeled and stylish interior featuring both Dutch & French doors letting in plenty of sunshine. A large private yard w/ covered outdoor living area creates the ultimate indoor/outdoor lifestyle. You're steps from the local grocery store, village shopping, coffee shops, restaurants, bars and the trolley. You could not ask for a better location!

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4.97 out of 5 average rating, 393 reviews

A spacious backyard is illuminated by string lights, creating a warm ambiance. Lush greenery, including tall palm trees and banana plants, frames the area. A wooden deck provides an outdoor seating space, while comfortable patio furniture is visible nearby. The sky displays soft pastel colors at twilight.

Home in Del Cerro

SDSU Beach Cottage

Welcome to our charming SDSU Beach Cottage! Centrally located in a desirable San Diego neighborhood, you're just 10 minutes from many of the city's top attractions. Steps away, you'll find popular local dining, a wine bar, pub, natural market, pizza shop, nail salon, liquor store, and Einstein Bros. Bagels. Enjoy San Diego's best or unwind in our tropical backyard featuring outdoor games and ping pong. Minimum age to book: 25.

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An open-concept living area is highlighted by vaulted ceilings and natural light from large windows. A spacious L-shaped sofa is positioned around a coffee table, facing a wall-mounted TV above a modern fireplace. Nearby, a dining area can be seen through an archway.

4.99 out of 5 average rating, 128 reviews

Spacious & Fun | 5br, 4.5ba | Hot Tub | Views

Experience sunny San Diego from this 5 bedroom, 4.5 bathroom foothill home. Wake up to panoramic views of the surrounding hillsides and gather in the spacious living and dining rooms. The home is conveniently located just 15-20 minutes from San Diego's famous beaches and top attractions. After a day of exploration, unwind in the backyard area featuring a hot tub, fire pit, pool table, and life-sized chessboard.

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The studio features a spacious bed adorned with a plush white quilt. A decorative basket with a bottle and glass rests on the bed. A cozy love seat is positioned nearby, complemented by soft grey curtains that frame the window, allowing natural light to illuminate the room.

4.97 out of 5 average rating, 157 reviews

Suite Charles Way: A Cozy Fletcher Hills Studio

This newly remodeled spacious studio retreat features a private courtyard with barbecue, kitchenette, a brand-new California King bed, and a reclining love seat with charging ports. Enjoy a relaxed cabana vibe, a charming neighborhood and treetop views with easy access to all your favorite San Diego destinations. Within minutes from Grossmont Sharp Hospital, Grossmont Center, the trolley and Grossmont College.

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Popular amenities for La Mesa house rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

House rentals with a pool

4.86 out of 5 average rating, 121 reviews

Entertainers Dream Pool Home

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A private pool is surrounded by a spacious patio, featuring a built-in spa and floating pool accessories. Lounge chairs are arranged by the poolside, while the nearby house is complemented by green shrubbery and playful palm trees. Bright sunlight highlights the inviting blue water.

4.9 out of 5 average rating, 110 reviews

QUIET HOME -3 Bedroom & Den, + POOL, sleep 8 plus

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4.98 out of 5 average rating, 132 reviews

A well-appointed backyard features a heated pool with a waterfall, surrounded by palm trees and lounge chairs. An outdoor dining area is under a covered gazebo, providing a view of the landscaped space. Soft evening light hints at a serene atmosphere.

Home in Spring Valley

Tropical Oasis: spa, solar heated pool, waterslide

LocationFamilyAccuracy

A spacious outdoor area features a clear blue pool surrounded by palm trees. Lounge chairs are positioned nearby, and a shaded table with chairs offers a spot for relaxation. The backyard showcases a privacy fence and ample sunlight.

4.85 out of 5 average rating, 257 reviews

San Diego Pool | Fire Pit | Sunshine | Sleeps 10

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Double glass doors provide access to the patio, revealing views of a kidney-shaped pool surrounded by a deck. Lush greenery and hills are visible in the background, creating a serene outdoor setting.

4.77 out of 5 average rating, 133 reviews

Views - Quiet Mt. Helix Home - Pool -Sleeps 11

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4.87 out of 5 average rating, 235 reviews

A serene outdoor space features a salt-water pool surrounded by a concrete patio and manicured grass. An umbrella provides shade over the poolside area, with lush greenery and mountains visible in the background under a partly cloudy sky.

Home in San Diego

Bright and spacious home with views, pool & spa.

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4.96 out of 5 average rating, 175 reviews

Beautiful 3,000 Sq Ft Tropical Oasis

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An open-concept living space features a modern kitchen with a large island and bar seating for four. A light-colored sofa is positioned nearby, with a stone fireplace adding warmth to the room. Natural light streams through the skylight and windows, enhancing the airy feel.

4.88 out of 5 average rating, 123 reviews

Bright Contemporary 5-Bedroom Oasis, Pool and Yard

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Weekly house rentals

A spacious living room features a large sectional sofa with orange accent pillows, complemented by a round coffee table. An island with bar stool seating is visible, along with modern kitchen appliances. Natural light enters through the nearby window, highlighting the warm wood tones of the decor.

4.95 out of 5 average rating, 106 reviews

Cozy Mid-Century Charmer | Huge Backyard | Firepit

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An outdoor patio area features a round table with four chairs, all adorned with colorful cushions. A large red umbrella provides shade, and a decorative rug adds vibrancy to the stone surface. Surrounding greenery and blooming plants create a serene environment.

4.98 out of 5 average rating, 341 reviews

Travel Writer's Pad

ValueLocationIndoor spaces

4.88 out of 5 average rating, 179 reviews

Home in Lemon Grove

Impeccable & private: cozy KING BEDS, FUN Patio

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4.98 out of 5 average rating, 162 reviews

The exterior of a single-family home is showcased, featuring a spacious driveway and a two-car garage. Mature cacti and landscaped greenery enhance the front yard, while a clear blue sky provides a bright background.

Home in Santee

Santee Gem: Luxe Modern Home, Spacious Backyard

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An inviting outdoor space features a large hot tub, surrounded by lush greenery and spots for seating. A fire pit surrounded by comfortable seating is visible, complemented by dining options beneath umbrellas. The space is gently illuminated by soft lighting, creating a cozy atmosphere.

4.97 out of 5 average rating, 75 reviews

The Sand House-Gorgeous 3BR-2B HotTub+FirePit+Turf

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4.95 out of 5 average rating, 20 reviews

New Mt. Helix Retreat with Views & Patio

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4.9 out of 5 average rating, 48 reviews

Sleeps 16 | 2 Hot Tubs, Theater, Gym & Mini Golf

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A welcoming porch area features comfortable outdoor seating, with a sleek coffee table placed between black wicker couches. Potted plants add greenery to the space, while a ceiling fan hangs above. The porch is accessible and provides a view of the surrounding area.

4.93 out of 5 average rating, 57 reviews

Oliver House in La Mesa

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Private house rentals

A cozy outdoor seating area features two white Adirondack chairs positioned beside a small round table. The inviting entryway of the tiny home is visible, surrounded by lush greenery and trees, creating a peaceful and refreshing environment.

5.0 out of 5 average rating, 49 reviews

Tiny Home with a View

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The charming cottage is framed by lush greenery and vibrant landscaping. A wooden bench sits on the patio, inviting relaxation, while the terracotta roof complements the light-colored exterior. Numerous windows and a welcoming entrance provide a glimpse into the bright and airy interior.

4.85 out of 5 average rating, 40 reviews

La Mesa Village Spanish Cottage

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A modern living space is highlighted with a comfortable gray sofa adorned with vibrant cushions. A textured golden coffee table is positioned in front of the sofa, topped with a game and a decorative bowl. Natural light floods the area, drawing attention to the art on the walls.

4.97 out of 5 average rating, 67 reviews

Hot Tub, BBQ, Patio, 4 min SDSU, Central San Diego

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The bedroom features a queen bed with crisp white linens and an orange textured throw pillow. A blue upholstered headboard adds color, while a bedside table holds a wooden lamp. A framed photograph of a pier at sunset is mounted on the wall.

4.97 out of 5 average rating, 75 reviews

La Mesa's Jewel Cottage

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A private backyard is showcased, featuring a sparkling pool with a waterfall and a jacuzzi. An umbrella provides shade over a seating area with lounge chairs. Lush trees and greenery surround the space, creating a tranquil ambiance.

4.97 out of 5 average rating, 61 reviews

La Mesa Pool Paradise.

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4.98 out of 5 average rating, 46 reviews

Helix Haven

LocationFamilyCleanliness

4.96 out of 5 average rating, 45 reviews

A spacious dining area features a glass-top table surrounded by eight wooden chairs with dark seats. A circular light fixture with multiple bulbs hangs above the table, complementing a soft pink arch design on the wall. A tall green plant adds a touch of nature to the room.

Home in San Diego

Casa Ciela•AC•Spa•15 min Downtown•Beach•Theatre

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