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Apartment holiday rentals in Panama City

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Panama City

Guests agree: These apartments are highly rated for location, cleanliness and more.

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Top Guest favourite
A modern living area features a light-colored sofa adorned with colorful cushions. A round coffee table sits on a textured rug, while a dining table for six is visible in the background. Large windows present striking views of the city skyline.
Apartment in Panama City
5 out of 5 average rating, 38 reviews

Luxury apt in Panama City 2 Rooms 3 Baths

El edificio Wanders by yoo esta ubicado en el corazón de la ciudad, es un proyecto fuera de serie donde cada rincón tiene una historia que contar. Recepción 24/7, muchas areas de esparcimiento, estación de hidratación. En las afueras del lobby tenemos la Cafetería cafe con teclas y un restaurante de Carnes Popino. En el area social servicio de barra en la piscinas, parque de niños, sala de juegos con pantallas en e l techo baños, salon de eventos, cocina para eventos, gym full equipado y más

Guest favourite
A rooftop area features a refreshing pool surrounded by sleek decking, with city views in the background. Comfortable lounge chairs are positioned alongside the pool, inviting relaxation. The modern architecture is complemented by large windows that enhance the overall openness of the space.
Apartment in Marbella
4.91 out of 5 average rating, 11 reviews

Exclusivo Apto/Av Balboa/Pool/Gym/AC/View/Parking

Vive una experiencia única frente al mar en este lujoso y amplio apartamento, disfrutarás de una piscina con vista directa al océano, perfecta para relajarte. El apartamento está completamente equipado para una estancia inolvidable. Además, el edificio ofrece amenidades premium como sauna, gimnasio, billar pool, parqueadero y una espectacular terraza con vista 360° de la ciudad. Situado en una zona céntrica, estarás a pasos de los mejores restaurantes, tiendas y atracciones locales.

Guest favourite
A balcony is featured with two stylish chairs and a small side table. Lush treetops are visible below, with a vibrant urban skyline in the background. Natural light illuminates the space, creating a serene outdoor setting for relaxation.
Apartment in Panamá
5 out of 5 average rating, 10 reviews

Cozy 1BR•Balcony Gym Rooftop Pool•Near Multiplaza

➤ Charming apartment, warmly decorated, balcony with enchanting views of lush treetops with the city's vibrant skyline in the distance. Minutes away from Multiplaza Mall . ★ Perfect for Remote Workers, 500 MB speed internet. ★ Walk 5-10 mins to Restaurants, Supermarkets, Multiplaza Mall, Cafes & Shopping ➤ Urban Escape - Building Highlights: ★ Gym ★ 2 Co-Working Spaces ★ Pool on the Rooftop Terrace ➤ Located in San Francisco: Explore the City Easily | Uber-Friendly

Guest favourite
A clear blue swimming pool is seen, reflecting sunlight under a bright sky. Surrounding greenery provides privacy, while a modern building stands nearby, featuring large balconies. The pool area is designed for relaxation and leisure.
Apartment in Panamá
4.92 out of 5 average rating, 200 reviews

Cozy apartment near Casco Viejo

Enjoy a stay in one of the most exclusive areas in the center of Panama, few minutes from Casco Viejo the Cozy Apartment City Center offers free WiFi, air conditioning and stunning views amidst skyscrapers. The apartment has one bedroom with a queen-size bed, a bath and shower, a sofa bed, two smart TV, a fully equipped kitchen, a washer and dryer, and a half bath. On the property there is a work area, a gymnasium, a community pool, and a barbeque area FREE PARKING

Superhost
The spacious bedroom features a comfortable queen-sized bed with fresh linens. Light from bedside lamps creates a soft glow. Unique tiled flooring adds character, and the slanted ceiling enhances the room's spaciousness. A piece of artwork is displayed above the headboard, contributing to the overall ambiance.
Apartment in Panamá
4.92 out of 5 average rating, 142 reviews

Perfect Location - Beautiful Apt in Casco Viejo

Peaceful, beautiful and spacious apartment in perfect location. Located in a quiet area of Casco Antiguo, just steps away from lively Plaza Herrera. It cannot get any better, as just across from this unit you have Museo de La Mola, also restaurant Fonda Lo Que Hay and Felipe Motta Wine Store. Downstairs you have one of the best pizzas in the neighborhood. It’s walking distance from the best coffee shops, restaurants, supermarkets, shops, pharmacies and more.

Top Guest favourite
Apartment in Panamá
5 out of 5 average rating, 7 reviews

Cozy apartment facing the sea.

This place is unique, it has its own style. Its location is strategic, it will be very easy to get there. It is located next to the Cinta Costera, near the metro station, Casco Antiguo, and all the tourist centers that Panama offers you. Come and enjoy this beautiful experience in one of Panama's finest buildings, offering tranquility, entertainment, gastronomy, cocktails, Panamanian history, and stunning views—all within the same building. Come visit us!

Guest favourite
A spacious living area features a combination of modern and vintage furnishings. A large turquoise sofa and a floral chaise lounge are complemented by a round coffee table and a green wooden chair. Exposed stone walls and large windows with blue accents create a warm ambiance.
Apartment in Panamá
4.98 out of 5 average rating, 148 reviews

Escape to the Heart of Casco with a Private Balcony

Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Top Guest favourite
An inviting living area is featured, showcasing a modern grey sofa accented with decorative pillows. A round glass dining table is surrounded by chairs, and artistic wall frames complement the space. Natural light is filtered through elegantly layered window shades.
Apartment in Panamá
4.97 out of 5 average rating, 118 reviews

Luxury apartment in downtown Panama, banking area

We have a strategic location right on the main road of Panama (Calle 50) Bella Vista. You will find yourself located in the heart of the banking area. Whether you're coming for work or vacation, this is the ideal place. You'll find all kinds of restaurants, shops, and shopping malls nearby. You'll have the Cinta Costera just a 10-minute walk away where you can walk or exercise. Fun and enjoyment within walking distance

Guest favourite
Apartment in Obarrio
4.94 out of 5 average rating, 17 reviews

Centrally located and safe + rooftop with pool and views

Modern 1 bedroom apartment in a safe, strategic and super central area of Panama City. Just a 5-minute walk from the Metro (Via Argentina) and surrounded by restaurants, supermarkets, cafes, banks, and more. Ideal for digital nomads, business travelers, tourists or couples. Cozy and functional design, perfect for short or long stays. Enjoy comfort, style, and an unbeatable location for exploring or working in the city.

Guest favourite
Apartment in Panamá
4.98 out of 5 average rating, 119 reviews

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Guest favourite
A private terrace features a jacuzzi surrounded by lush greenery against an exposed stone wall. Wooden decking creates a warm ambiance, complemented by two lounge chairs designed for relaxation, offering an inviting outdoor space for guests.
Apartment in Panama City
4.9 out of 5 average rating, 153 reviews

Jacuzzi in colonial ruins in beautiful apartment

Welcome to Casa Marquez Portazgo! This cozy apartment in the heart of Panama City offers comfort and convenience, ideal for your stay. With one bedroom and capacity for two people, you'll enjoy a relaxing atmosphere in 70 m². Located in the San Felipe neighborhood, just steps from the entrance to the Casco Antiguo, it offers a unique experience. You can also unwind in the jacuzzi.

Guest favourite
A modern living space features a light-colored sofa accompanied by a round coffee table. A large television is mounted on a decorative wall behind the sofa. Natural light streams through tall windows dressed with sheer curtains, enhancing the cozy atmosphere.
Apartment in Panamá
4.94 out of 5 average rating, 49 reviews

Elegant apartment with a view & the warmth of home

This apartment with the warmth of home, elegant and comfortable with spectacular views of the city, located in one of the best areas of Panama City, surrounded by places of interest such as restaurants, commerce and the most important banking area of ​​the city, and its proximity to the Iglesia del Carmen metro station provides easy transportation in and out of Panama City.

Popular amenities for Panama City apartment rentals

Quick stats about apartment rentals in Panama City

  • Total holiday rentals

    Explore 2,770 holiday rentals in Panama City

  • Nightly prices starting at

    Panama City holiday rentals start at $18 NZD per night before taxes and fees

  • Verified guest reviews

    Over 71,040 verified reviews to help you choose

  • Family-friendly holiday rentals

    850 properties offer extra space and kid-friendly amenities

  • Pet-friendly accommodation

    Find 990 rentals that welcome pets

  • Holiday rentals with a pool

    1,730 properties feature pools

  • Rentals with dedicated workspaces

    1,720 properties have a dedicated workspace

  • Wi-Fi availability

    2,640 of Panama City holiday rentals include Wi-Fi access

  • Popular amenities for guests

    Guests love Kitchen, Wi-Fi and Pool across Panama City rentals

  • 4.7 Average rating

    Panama City stays receive an average rating of 4.7 out of 5 from guests

  • Nearby attractions

    Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)

Destinations to explore