
Apartment holiday rentals in Panama City
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Top-rated apartment rentals in Panama City
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Cozy Designer Stay at Yoo & Arts Panama
Experience an elegant, modern apartment with the and comfort that makes you feel right at home from the start. Located on the prestigious Avenida Balboa, in the iconic Yoo Panama & Arts Tower, this space blends designer style with unbeatable comfort. You'll be surrounded by top-rated restaurants, shopping centers, and just minutes from the historic charm of Casco Viejo — the city's most iconic neighborhood. Perfect for travelers who value great design, location, and an unforgettable stay. 🏙️✨

Chic Studio in Casco Antiguo - View to Main Plaza
Located in trendy Casco Antiguo, this studio apartment is walking distance of restaurants, cafes, supermarkets, pharmacies and the overall life of Casco. The building has recently been renovated and has a beautiful view of Plaza Catedral. Note: As seen on previous comments, there used to be a bar club in the rooftop and at the bottom of the building. Good news, there are no more bars in the building and the studio has soundproof doors as Casco is an area with the best nightlife in Panama.

private ocean view studio apto.
The Sand Avenida Balboa cuenta con apartamentos tipo estudio de 24 metros, amueblado y con acabados, cada apartamento cuenta con una pequeña cocina, baño privado, armario y muebles cómodos; incluyen ventanas de piso a techo. The Sand Avenida Balboa está idealmente ubicado en el corazón de la ciudad de Panamá, Avenida Balboa con fácil acceso al centro, al Casco Antiguo y a menos de 5 minutos de Causeway y el BiomuseoDisfruta de una experiencia con estilo en este alojamiento céntrico.

Tropicool Loft w/rooftop steps from Casco
This historic 1941 loft is located at the entrance of Casco Viejo where you’re steps from the fish market and all the cool cafés, rooftops, and trendy restaurants that make up the neighborhood. Fully equipped kitchen, washer/dryer combo, 1.5 bath, bedroom on 2nd floor, 2 balconies + communal rooftop, projector w/Netflix, fast internet, and great AC. You’re also directly in front of the Cinta Costera park for running, biking, tennis courts. Near local airport for flights to Bocas!

Moderno apartamento con vista/Piscina y Rooftop
Relájate en este apartamento moderno y luminoso, con vista panorámica a la ciudad, piscina y rooftop, ubicado en calle 50 ubicado en unas de las zonas mas céntricas y convenientes de Panamá Descubre una experiencia cómoda y segura en pleno corazón de la ciudad, a pocos pasos de Casco Antiguo y de la estación del metro Iglesia del Carmen. Su ubicación privilegiada te conecta con zonas comerciales, restaurantes, la cinta costera y los principales puntos de interés de la ciudad

Escape to the Heart of Casco with a Private Balcony
Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Amazing loft with an iconic view of Casco Viejo
Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, in a central location in Casco Viejo (the old city). You will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. Located in “Jeronimo,” this restored- colonial building was built in the year 1850, and features unique crafted wall décor, as well as some of the original "calicanto" walls.

Private parking & rooftop | Studio Casco Center
This beautiful restored studio from the 1870s blends history with modern design. Enjoy a private rooftop terrace with seating and BBQ, plus private PARKING—ideal after exploring Casco's best restaurants, galleries, and nightlife steps away. ✨ Highlights: - Historic Charm: Original tile floors and exposed colonial stone walls. - Comfort: King bed, living room, and full kitchen. - Amenities: Private rooftop & private PARKING. - Great location

Cozy Studio in Cinta Costera with Home Vibes
✨ Live the "Cinta Costera Vibes" experience 🌴 from this modern studio apartment with a panoramic view of the Bay and the vibrant Balboa Avenue. Perfect for travelers looking for comfort, style, and a premium location. Enjoy the pool, restaurant, gym, and rooftop with the best sunset in Panama 🌅. Ideal for short or long stays — your home with home warmth and a 5⭐ touch. Save it as a favorite and live the Host Up experience!

k*| Delightful 1 BR w/King Bed in Calle 50
Calle 50 es el Times Square de la Ciudad de Panamá. Esta emblemática calle resguarda a la concurrida Area Bancaria. La ubicación del apartamento es excepcional y céntrica, cercana a: ->Estación Iglesia del Carmen [Línea 1 del Metro de Panamá] ->Cinta Costera ->Parque Urracá ->Supermercado Rey ->F&F Tower (Edificio del "Tornillo") ->Nightlife en Calle Uruguay Desde el piso 19 se ofrecen vistas a la ciudad y a la selva.

Full apartment in Panama
This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Jacuzzi in colonial ruins in beautiful apartment
Welcome to Casa Marquez Portazgo! This cozy apartment in the heart of Panama City offers comfort and convenience, ideal for your stay. With one bedroom and capacity for two people, you'll enjoy a relaxing atmosphere in 70 m². Located in the San Felipe neighborhood, just steps from the entrance to the Casco Antiguo, it offers a unique experience. You can also unwind in the jacuzzi.
Popular amenities for Panama City apartment rentals
Weekly apartment rentals

Beautiful apartment in Casco Viejo ST. George D

New apartment in the heart of Panama

Cozy apartment in Panama

Elegant Apt in Costa del Este. Premium Amenities

Luxury 2BR w/Ocean Views – 27th Fl, Wanders YOO

Luxury Centric 2BR Apartment in Casco Viejo

2BR King Suite Ocean View, Casco, Canal 500MB WIFI

Exclusivo Apto/Av Balboa/Pool/Gym/AC/View/Parking
Private apartment rentals

Oceanview 1BR in Yoo Panama

A cozy Casco Viejo apartment

Ocean-view with industrial design

Beautifull 1BR Apt With Comfy Hotel Linens

Suite Luxury 30th View , Cinta Costera Panama

Best Location, Beautiful Apartment, Panama

Unique Luxury 3-story Loft at the Yoo

Panama Dream View Escape
Apartment rentals with a hot tub

Apartment between ocean and jungle

Luxury Apartment in Panama | 2BR + Views + Pool

PH Yoo 44i – Ocean View Apartment

New Flat with Ocean + City Views

Spacious Oceanfront Apartment

Tropical Paradise at Playa Bonita

Coastal Chic Executive Studio in Panama City

On the beach. Entire floor with oceanfront terrace
Quick stats about apartment rentals in Panama City

Total holiday rentals
Explore 2,890 holiday rentals in Panama City

Nightly prices starting at
Panama City holiday rentals start at $17 NZD per night before taxes and fees

Verified guest reviews
Over 79,200 verified reviews to help you choose

Family-friendly holiday rentals
900 properties offer extra space and kid-friendly amenities

Pet-friendly accommodation
Find 1,090 rentals that welcome pets

Holiday rentals with a pool
1,840 properties feature pools

Rentals with dedicated workspaces
1,770 properties have a dedicated workspace

Wi-Fi availability
2,760 of Panama City holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Kitchen, Wi-Fi and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)
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- Things to do Panama
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