
House holiday rentals in Panama City
Find and book unique houses on Airbnb
Top-rated house rentals in Panama City
Guests agree: These houses are highly rated for location, cleanliness and more.

On the beach, entire apartment, panoramic terrace and more
For those who love: Sea, Sun, Tropical, Tranquility, Freedom, Comfort. This exclusive apartment, directly on the beach, offers a unique view of the Gulf. Enjoy sunsets, sunrises, and walks. - On the large panoramic terrace, a sea-view bathtub. Sofa. Unique emotions. - 360° panoramic view with palm-leaf roof. - Queen bed, sofa, bathroom with shower, kitchen. * In the beachfront social area: - Hammock, barbecue, sofas, gazebo, kitchen, pool. Dcent of Paradise Pure Life Suitable for long stays.

Central|Confort|surrounded by nature|Wifi|parking
Conectar con la ciudad y la maravillosa naturaleza al mismo tiempo. Descansar en una hamaca en el balcón lo hace único. Te quedará genial si deseas visitarnos de placer, trabajo (WiFi de alta velocidad); en familia o en grupos de amigos. Casa de la Antigua Zona del Canal, Primer Alto; desde aquí para explorar lugares turísticos y restaurantes. (Cerca Terminal de Buses, Metro Tren, Albrook Mall, parque Metropolitano, Aeropuerto Marcos Gelabert, Casco Antiguo, Coast Way de Amador, Canal de 🇵🇦)

Cantabria House - 10 minutes from the Airport
Spacious and comfortable home just 10 minutes from Tocumen Airport and only 200 meters from the Metro. Perfect for families, groups, or business trips. Fast 500 Mbps Wi-Fi, 3 bedrooms, 2 full bathrooms, fully equipped kitchen, air conditioning throughout the house, cable TV, patio with outdoor furniture, private parking, and self check-in. Long layover, family trip, or work in the city? This home has it all: comfort, location, and privacy. Book now and feel at home from the very first moment!

Mountain Retreat
Relax and unwind at this peaceful property nestled on two hectares of lush tropical vegetation surrounded by the sights & sounds of nature. Located at Panama's Blue Mountain(Cerro Azul), 30 kilometres from Panama City. This cozy & comfortable home is equipped with modern amenities & chic decorative touches. It consists of a main house with 2 bedrooms & a 2 bedroom cottage. It has a spacious terrace, pool & jacuzzi overlooking Panama City. The property also boasts its own spring water well

Apartamento Lilia Airport 1
"Experimenta una estancia cómoda y conveniente en nuestro acogedor apartamento, ubicado a solo 10 minutos del aeropuerto Tocumen. Equipado con todas las comodidades necesarias para tu descanso, desde conexión WiFi hasta una cocina equipada, este espacio te ofrece la oportunidad de relajarte y recargar energías. Disfruta del confort del aire acondicionado, agua caliente/fria en el baño, una cama y sofá cama para tu comodidad, televisión con cable , y toallas y sobrecama para tu conveniencia.

Charming House in Casco Viejo
This recently renovated house is an absolute treasure. It blends history, charm, and modern comfort. Archeologists uncovered artifacts dating to the seventeenth century. Tastefully furnished with modern comforts and antiques, it's steps away from the Panama Canal Museum and in the heart of Casco Viejo, perfect for guests looking to immerse themselves in the cultural and culinary delights before retreating to the comfort and tranquility of their temporary home.

A Charming Colonial House in Casco Antiguo
Welcome to Casa Arango, a beautifully restored 19th-century gem in the heart of Casco Antiguo. Located on a quiet, picturesque street, this colonial house blends historic charm with modern comforts. Casa Arango offers three elegant rooms with private bathrooms, a front balcony, and a spacious patio with a barbecue and private bar. Perfect for families or groups of up to 8, the property also includes two private parking spaces—an exclusive luxury in the area.

Beautiful spacious full apartment near Albrook
Spacious and cozy apartment in a very quiet area surrounded by nature. The apartment is complete, everything is ready to welcome you. All services are included. Close to the Miraflores locks, Ciudad del Saber, the Metropolitan National Park, Cerro Ancón, and Albrook Terminal. Close to the Los Ríos pool. Accessibility for buses and taxis. For security reasons, cameras in the main entrance, terrace and patio. There are no cameras in indoor spaces.

Wonderful nature
Enjoy a family retreat in the heart of nature, where tranquility envelops you. This cozy accommodation, surrounded by a beautiful garden in the Metropolitan Natural Park, offers you a unique escape just 3 minutes from Albrook Mall and 5 minutes from downtown. Wake up to birdsong and a visit from the ñeques (agoutis), while relaxing in an exclusive and lively atmosphere. The perfect getaway to disconnect and enjoy nature with all the amenities!

Spacious Panama House in the 'heart of the city'
You couldn't ask for a better place to stay while you visit Panama. This location is perfect, while other properties might advertise similar amenities; not one of them can boast a combination of space and amazing location quite like this one. This is very private & secure property in a fantastic, & very safe area right in the heart of the city & close to everything! An oasis in the middle of the city with AC IN EVERY ROOM AND DININING ROOM.

Cozy house in Casco Viejo with private pool
Historic accommodation in the heart of the Old Town Enjoy a unique experience in this accommodation located in the center of the Old Town. The property has been carefully restored several times by renowned Panamanian architects, including Sebastián Paniza. Among its most outstanding features is a historic well within the property, as well as original walls and floors that preserve the spirit and authenticity of the place.

Private Studio 10 Min from the Airport!
Entire apartment 10 minutes from the airport! The apartment is fully furnished including appliances and kitchen items, toiletries, dining room, work table and more. Just a few minutes walk from the SAN ANTONIO METRO Station, restaurants, shopping malls, laundries, supermarkets and pharmacies. We offer tours to San Blas to make the most of your trip. Our house is your house in Panama 🇵🇦
Popular amenities for Panama City house rentals
House rentals with a pool

Luxury Home with Pool in the Best Neighborhood

A beautiful apartment with a swimming pool, BBQ area, and gym

Nice duplex house with a swimming pool.

Villa Helena 3 Bedrms Los Altos de Cerro Azul

House of the waterfalls

Airbnb - Vacation

Entire house

Your country house, Menus de la Montaña, awaits you.
Weekly house rentals

Modern house with a/c 10 mins from airport

Modern and minimalist Altos de Cerro Azul

House near the airport

Your Little House in Linda Vista

Casco Viejo 02, Luxury Condo, Panama Bay.

Comfortable house in the nature of Panama Pacifico

LovelyviewPty House 15 minutes away from the airport

Cabin in Cerro Azul with Forest View
Private house rentals

2 bedroom apartment in the heart of Panama

Country house in Altos de Cerro Azul

Casa Amarilla

2 bedroom house, 2 bathrooms, kitchen, dining room, in Ancon

Beautiful house in Brisas del Golf

House with spectacular city and ocean views

Casa de Montaña Altos de Cerro Azul

The Bird's Nest - Cerro Azul
Quick stats about house rentals in Panama City

Total holiday rentals
Explore 470 holiday rentals in Panama City

Verified guest reviews
Over 7,710 verified reviews to help you choose

Family-friendly holiday rentals
180 properties offer extra space and kid-friendly amenities

Pet-friendly accommodation
Find 160 rentals that welcome pets

Holiday rentals with a pool
90 properties feature pools

Rentals with dedicated workspaces
230 properties have a dedicated workspace

Wi-Fi availability
430 of Panama City holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Kitchen, Wi-Fi and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)
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- Things to do Panama
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