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Hotels in Panama City

Find and book unique hotels on Airbnb

Quick stats about hotels in Panama City

  • Total holiday rentals

    Explore 190 holiday rentals in Panama City

  • Nightly prices starting at

    Panama City holiday rentals start at $17 NZD per night before taxes and fees

  • Verified guest reviews

    Over 5,050 verified reviews to help you choose

  • Family-friendly holiday rentals

    10 properties offer extra space and kid-friendly amenities

  • Pet-friendly accommodation

    Find 30 rentals that welcome pets

  • Holiday rentals with a pool

    80 properties feature pools

  • Rentals with dedicated workspaces

    140 properties have a dedicated workspace

  • Wi-Fi availability

    190 of Panama City holiday rentals include Wi-Fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Panama City rentals

  • Nearby attractions

    Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)

Top-rated hotels in Panama City

Guests agree: these hotels are highly rated for location, cleanliness and more.

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A room featuring two twin size bunk beds is illuminated by natural light from a window dressed in turquoise curtains. A small blue chair sits beside a marble-top table, adding a touch of color to the neutral-toned walls and flooring.
Hotel room in Bella Vista
4.75 out of 5 average rating, 4 reviews

Private Twin | Shared Bathroom

This double room has 2 twin size bunk beds, air conditioning, shared bathroom with a showerand toiletries. This cozy place is super convenient, with easy access to shops, restaurants, public transportation, and popular spots like the “Mercado del Marisco”, Casco Antiguo, the Causeway, and more… The shared full kitchen will be the perfect place for you to hang out with other guests and cook up your favorite meals while you’re here!

A well-lit room features two cozy queen-sized beds with gray bedding. A colorful mural of green leaves and yellow flowers adorns one wall. Nightstands with lamps are positioned beside each bed, while a window with light brown curtains provides natural light.
Hotel room in San Felipe
4.57 out of 5 average rating, 274 reviews

Hotel Caracas Casco Viejo - 2 Queen Beds Room

✨ Welcome to Hotel Caracas, a charming boutique stay in the heart of Casco Viejo, Panama’s UNESCO-listed gem! 🌆 Located in front of beautiful Plaza Santa Ana, explore the city on foot and enjoy the perfect mix of local life and tourist spots. 🛏️ Each room offers full privacy, a private bathroom 🚿, a peaceful space to relax, and Wi-Fi 📶. 🕒 24/7 front desk, top value 💰 ⭐️ Highly recommended for a unique stay⭐️

Hotel room in San Felipe
4.75 out of 5 average rating, 12 reviews

Comfort Room

Welcome to your retreat in the heart of the old town! This spacious room in our charming hotel combines historic charm with modern amenities for an unforgettable stay in Panama City. Located in an incredibly central location, you will be within walking distance of the main points of interest such as Historic Centers, Panama Interoceanic Canal Museum, Mola Museum, Restaurants, Nightclubs and restaurants.

A spacious room is presented with a double bed, topped with a gray blanket and neatly folded towels. Wooden bedside tables sit on either side, each adorned with lamps. A decorative wall adds subtle interest, while a window provides natural light.
Hotel room in Panama City
4.62 out of 5 average rating, 180 reviews

Bedroom and private bathroom in Panama City Center

We are an accommodation opened in October 2020 located in downtown Panama City. We have several types of rooms. In this case, it is a room with 1 double bed. We offer continuous reception service, high-speed Wi-Fi, shared work area, room with snack and coffee vending machine and 24-hour security. Our rooms are fully equipped with a private bathroom with hot water, a desk, air conditioning and cable TV.

Hotel room in Bella Vista
5.0 out of 5 average rating, 3 reviews

Deluxe Adapted for People with Reduced Mobility

Welcome to our adapted room on the first floor of Hotel Mio Panama, designed for people with reduced mobility. With 30 m², it combines an adapted, modern and elegant design. Enjoy comfort and independence, along with a practical setting in the heart of the city. The hotel also offers a gym, restaurant and a rooftop pool. Enjoy an unforgettable experience in a cozy and fully equipped environment.

Guest favourite
Hotel room in Panama City
5.0 out of 5 average rating, 5 reviews

Executive Suite Financial District/Pool·Gym

Elegant suite located in the Megapolis Hotel, in the heart of Panama City. Modern and comfortable space, ideal for business trips or tourism. Strategic location near the Financial District, restaurants, shopping malls, nightlife and tourist attractions of the city. Enjoy access to high-level common areas, pool, gym and amenities that combine meals, rest and entertainment in one place.

A cozy hotel room is showcased with a spacious bed dressed in white linens and a red throw blanket. A wooden desk with two cups and a remote is positioned beside the bed. A soft lamp and a wall-mounted TV complete the inviting atmosphere.
Hotel room in El Cangrejo
4.76 out of 5 average rating, 45 reviews

Hotel room #3 one block from the Metro.

Enjoy quick access to Panama City's most popular destinations, shopping malls, restaurants, and tourist areas. Hotel room with private bathroom, air conditioning, cable TV, 24-hour reception, and parking subject to availability. Close to restaurants and casinos. One block from the Metro station that takes you in 10 minutes to Albrook Mall, the largest shopping mall in Panama.

Guest favourite
A cozy room features a double size bed with striped bedding and a piece of artwork above. A glass-enclosed shower is visible to the right, with a small stool nearby. Soft natural light filters through a sheer curtain, illuminating the space.
Hotel room in San Felipe
4.79 out of 5 average rating, 70 reviews

Beautiful small loft #3 - double size bed

Enjoy charming "Corcho rooms" in the heart of touristic Casco Viejo district of Panama City. We carefully restored old colonial building and converted it to the restaurant and apartments upstairs. "Corcho" is luckily situated in the central, restored part of Casco. Most of the buildings around are restored and the neighborhood is safe.

Guest favourite
Hotel room in San Felipe
5.0 out of 5 average rating, 5 reviews

Superior Room at Hotel Bardot Boutique

Welcome to our lovely room at Bardot Boutique, where style and character merge to give you an unforgettable experience! With space for 2 people and 30 m², this accommodation offers you a cozy and carefully designed atmosphere in the heart of the Casco Viejo of Panama.

Hotel room in El Cangrejo
5.0 out of 5 average rating, 4 reviews

Hostal El Prado in El Cangrejo Double Room

Bella Vista, El Cangrejo, Panama The hostel offers rooms with air conditioning, a wardrobe, a safe, a flat-screen TV, a terrace, and a private bathroom with a shower. At Hostal EL Prado, rooms include bedding and towels.

A spacious guestroom is featured, showcasing a large bed with crisp white linens and a striped accent throw. A mounted flat-screen TV is positioned on the wall opposite the bed, and a small table with a single chair is placed nearby.
Hotel room in Panama City
4.8 out of 5 average rating, 5 reviews

Single room for 2 with breakfast included

We are an Executive Hotel, located in the center of the beautiful city of Panama, near the Cinta Costera, Casco Antiguo, the Museum of Biodiversity, the Panama Canal, among other locations. Come and enjoy our services!

A comfortable sleeping area features a spacious bed dressed in neutral tones. Wooden headboards are complemented by bedside lamps. Natural light filters in through a large window, covered by light, flowing curtains. A small nightstand is positioned on each side of the bed.
Hotel room in Bella Vista
4.66 out of 5 average rating, 177 reviews

Your second home in Panama.

Our rooms are located in a prime area in the heart of the city's Financial and Banking sector. We are two blocks away, two stations from the Metro transportation system. 15 minutes from some Shopping Centers.

Popular amenities for Panama City hotels

Destinations to explore