
Guesthouse holiday rentals in Panama City
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Top-rated Guesthouses in Panama City
Guests agree: These guesthouses are highly rated for location, cleanliness and more.

Smart Stay by SS • Budget Studio 3+ Airport & Mall
This luxury budget studio is located just 11 minutes from Tocumen Airport and very close to the Panapark Free Zone, making it ideal for both business and transit travelers. The space includes Wi-Fi, a TV with Netflix, and is surrounded by supermarkets and stores. It’s a simple, private, and comfortable place to rest. ✅Perfect for engineers and business travelers looking for a good, nice, and affordable place to stay. ✔ Fast Internet ✔ Self check-in ✔ Modern and secure spaces ✔ A/C

Efficiency Bungalow - Metropolitan Natural Park
Casita Curundu is located in a quiet and beautiful neighborhood next to the Metropolitan Natural Park. A naturalist delight right in the city, surrounded by an urban jungle forest teeming with birds and wildlife. An amazing place for a couple to stay - you’ll have all the privacy you need but still be close to all the great attractions and the large shopping and transportation hub Albrook Mall, Airport, Bus & Metro Station and yet removed from the hustle and bustle of the city.

Trendy Tiny Apartment in Ancon
Nestled in the former Canal Zone, this cozy apartment offers comfort, nature, and city access. Near the City of Knowledge, The Panama Canal and Albrook, it’s perfect for exploring history and culture. We proudly welcome LGBTQ+ travelers and allies to a safe, inclusive space where you can relax and feel at home. Whether you're a solo traveler, a couple, or a digital nomad, you’ll find a warm, affirming environment here. Enjoy tropical hikes, city views, and local events. 🌈

Rare find: central+urban+ private green yard
Wake up to the sound of birds in this peaceful retreat in the heart of trendy and safe "El Cangrejo" neighborhood. Housed on the ground-floor apartment of a 2-story building built in the 50's. Features a private green yard — perfect for relaxing or spotting hummingbirds with an outdoor dining set. Steps from cafés, galleries, parks, metro, nightlife and many restaurants. Only one other neighbor on site. Private parking. Thoughtfully decorated to help you feel at home.

villa serena
Comfortable two-level home, ideal for families or groups. It has 3 bedrooms: the main one with a private bathroom and air conditioning, the other two have portable fans. TV room, dining room and equipped kitchen. It has parking and the entrance is shared with another accommodation. Perfect for quiet and well-located stays. Outside the city, west of Panama, Arraijan Vista Alegre, an hour from Panama City, you can visit the beaches of the interior of the country.

Garden Cottage in Panama City
Welcome to our charming cottage, an oasis in the heart of the city, ideal for nature lovers and comfort seekers. Located in a central area, this retreat offers the perfect combination of tranquility, comfort, and proximity to Panama's main attractions. Enjoy the balance between urban life and the serenity of the natural surroundings. It features a private entrance, a spacious garden, a barbecue area, and a terrace where you can relax and connect with nature.

Convenient, centrally located suite with parking
This special place is close to everything, making it easy to plan your visit. 5-10 minutes to any attraction in Panama City. Assigned parking and two blocks from major bus stop that can take you anywhere in the city or accross the country. You will have the entire place for yourself with independent entry, air conditioning and kitchen. There are four grocery stores walking distance. You can exercise daily at a park located behind the property.

Private studio annex near Costa del Este
Small, very nice and cozy studio type annex (all in one area) very cozy, super nice, clean. Annex adjacent to our house, private and independent with all the amenities inside it for your stay, with split air conditioning, smart TV, wifi, large bathroom shower with hot water, kitchen with all its appliances, area to park a car. Located in a very quiet residential area, a very good area. Great location. Just minutes away from Costa del Este.

Cool Guesthouse+WiFi+Pool+Tv+AC @ Panama Canal
✔️Verified Superhost! Your stay will be in the best hands Guest house, Near the City of Knowledge 🇵🇦 📍 In the tropical forest of the old Clayton base, with amenities, parks, sports and gastronomy. Close to the city, shopping malls, the Miraflores Locks and the transoceanic railway🇵🇦 We offer: 💧 Hot Water 📶 Wifi ❄️ AC 🏊♂️ Pool 📺 Smart TV and Cable 🚗Parking This strategic location, with a high level of security in the area.

Apartment in a safe residential area
You'll be close to everything when you stay at this centrally located accommodation. About 20 minutes from Tocumen Airport, 15 minutes from Romel Stadium, passing through Colon Free Zone near shops, restaurants, pharmacies, supermarkets, cinemas, easy transportation. Whether the trip is for work, as a tourist, or in transit through Panama, you can be comfortable in this apartment. We are available if you need additional information.

CASA PINO, a forest in the city
Excellent independent studio apartment with everything you need, private bathroom, kitchenette, fridge, and WiFi. Very safe. You can use machines in the park to exercise. We are located in a privileged area on the banks of the Canal, with lots of vegetation and forests, but very close to all the recreational amenities of the City of Knowledge. Very central, 10 minutes by metro-bus to Albrook Mall, 10 minutes from the Panama Canal.

Private guest house in Ancón
Enjoy the simplicity of this cozy, quiet, and centrally-located accommodation. Close to places of interest such as the Panama Canal Administration building, Amador Causeway, Albrook Mall, and several restaurants. Personally decorated to provide comfort... large windows in the bedroom provide natural lighting and a view of the garden and green area through the windows; yet it maintains the desired privacy and tranquility.
Popular amenities for Panama City guesthouses
Family-Friendly guesthouses

Casa Relic - Room #3 Mixed Dormitory

Casa Relic - Room #4 Mixed Dormitory

Espectacular habitación doble para 4 personas

Private Ensuite Room

Casa Relic - Room #2 Mixed Dormitory

Female Dorm in Smart Hostel

Super Economy Express Stay with tour options

Pour 4 personnes 2 chambres séparées dans parc
Guesthouses with a patio

Luxury Ecolodge

EY1 l Habitacion c/entrada privada en Marbella

Recamara#6+kitchen+WiFi+A/C+Cerca al metro

Room+Parking+TV+Kitchen+Work Area+WiFi@PanamáCity

Accommodation near Tocumen Airport

Separate entrance room with private bathroom.

Triple Room in Smart Hostel

Private suite
Guest house rentals with a washing machine and dryer

Where Rosie 550 x one year.100 LJ /125vsd/furnished.

THIS CONDITION

Room, nature, sauna and eveything, near the sea.

Smart Stay by SS • Budget Studio 5+ Airport & Mall

Rent a furnished room in San Antonio

Apto - Studio A/c Wifi .

The Black Studio by SS • near airport & city

Ocean front Apartment by San Francisco, PTY
Quick stats about guesthouse rentals in Panama City

Total holiday rentals
Explore 80 holiday rentals in Panama City

Nightly prices starting at
Panama City holiday rentals start at $17 NZD per night before taxes and fees

Verified guest reviews
Over 1,640 verified reviews to help you choose

Pet-friendly accommodation
Find 20 rentals that welcome pets

Holiday rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
30 properties have a dedicated workspace

Wi-Fi availability
80 of Panama City holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Kitchen, Wi-Fi and Pool across Panama City rentals

Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)
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- Things to do Panama
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