
Apartment holiday rentals in Panama City
Find and book unique apartments on Airbnb
Quick stats about apartment rentals in Panama City

Total holiday rentals
Explore 3,150 holiday rentals in Panama City

Nightly prices starting at
Panama City holiday rentals start at $17 NZD per night before taxes and fees

Verified guest reviews
Over 97,220 verified reviews to help you choose

Family-friendly holiday rentals
1,010 properties offer extra space and kid-friendly amenities

Pet-friendly accommodation
Find 1,180 rentals that welcome pets

Holiday rentals with a pool
2,170 properties feature pools

Rentals with dedicated workspaces
2,060 properties have a dedicated workspace

Wi-Fi availability
3,090 of Panama City holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Kitchen, Wi-Fi and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)
Top-rated apartment rentals in Panama City
Guests agree: These apartments are highly rated for location, cleanliness and more.

New Flat with Ocean + City Views
Brand new apartment in a high rise in the middle of downtown Panama. Very centrally located. Two fully furnished rooms and fully equiped kitchen. Gorgeous views of the city and Pacific ocean. Guests will have access to all the building's amenities such as a pool, gym, coworking space and game room. 15 minutes walking distance to Casco Viejo. 5 minute walking distance to Mercado de Mariscos, Cinta Costera and to the 5 de Mayo Metro Station. Airport Pickup and Dropoff Services Also Available.

Ocean View Apt in Panama, Yoo&Arts
Iconic luxury at Yoo&Arts Panama. This spectacular 130m² (1,400 sq ft) apartment offers sophisticated design and a breathtaking panoramic view of the Pacific Ocean. Enjoy breakfast on the balcony with an exceptional breeze, watch the sunrise from your bedroom, or work in an inspiring environment. Located on Avenida Balboa, the city's most exclusive area, you’ll have direct access to fine dining inside the building, premium supermarkets, and shopping malls nearby.

Stunning Terrace Among Ruins in Casco Viejo
Welcome to your Casco Viejo retreat! This spacious apartment, perfect for up to 8 guests, offers a unique blend of modern comfort and historic charm in Panama City’s most iconic neighborhood. Located in the heart of Casco Viejo. The highlight of this beautiful space is the stunning terrace nestled among historic ruins, where you can relax, enjoy a meal, or simply take in the timeless atmosphere. This is more than a stay – it’s an unforgettable experience.

Luxury apt in Panama City 2 Rooms 3 Baths
The Wanders by yoo building is located in the heart of the city. It is an extraordinary project where every corner has a story to tell. 24/7 reception, many recreation areas, hydration station. Outside the lobby, there is the Cafetería cafe con teclas and a Popino Carnes restaurant. In the social area, bar service in the pools, children's park, games room with screens on the ceiling bathrooms, function room, kitchen for events, fully equipped gym and more

The apartment of a legendary Panamanian footballer
Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Apartment in the Causeway Amador
Forget your worries in this spacious and serene space. Where you can enjoy the views of the Panama Canal and see the boats that pass through it, a space full of amenities with a perfect location, you can walk through the streets of the Causeway, visit the Biodiversity Museum, restaurants of various specialties, amusement park, bike rides etc, everything comes together to make this vacation an unforgettable experience for your whole family

The Yellow by Sukha | Metro Vía Argentina
Discover Panama City from a prime location. The Yellow by Sukha is a complete, modern and comfortable apartment for up to 4 guests, located in Vía Argentina, one of the most central, walkable and dynamic areas of the city. The Vía Argentina Metro station, restaurants, cafes, supermarkets, bars, and entertainment options are within walking distance. You'll also be very close to Obarrio and the Sortis Hotel, Spa & Casino area.

Luxury apartment in downtown Panama, banking area
We have a strategic location right on the main road of Panama (Calle 50) Bella Vista. You will find yourself located in the heart of the banking area. Whether you're coming for work or vacation, this is the ideal place. You'll find all kinds of restaurants, shops, and shopping malls nearby. You'll have the Cinta Costera just a 10-minute walk away where you can walk or exercise. Fun and enjoyment within walking distance

The best view of the Old Town
Welcome to this charming accommodation located in the heart of Casco Viejo, on the third floor facing one of the most iconic squares in Panama, Plaza Catedral! Thanks to its privileged location, you will enjoy a unique view of the square and the imposing Cathedral Church. Right in this lively square, you will have at your disposal a wide variety of restaurants and shops where you can buy souvenirs of this wonderful trip.

Full apartment in Panama
This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

YOO Panama | Luxury Stay & Panoramic Bay View
✔️ Superhost | Yoo Panama 🇵🇦 🏙️ Enjoy an exclusive apartment designed by Philippe Starck, with spectacular views of the bay and a prime location on Av. Balboa. 🌊 ✨ It has Wi-Fi, Smart TV, equipped kitchen, A/C, queen-size bed and private bathroom. 🏊♀️ Access to resort-style pool, gym, spa, restaurant, parking, and 24/7 security. 🆔 Only pre-registered guests with ID may enter.

Modern, central and comfortable (001)
Modern and cozy studio in the heart of Panama. Perfect for exploring the Old Town, the Coastal Strip and more. Full kitchen, full bed, double sofa bed, air conditioning, fast WiFi and private bathroom. Ideal for 1–4 people. Private access, elevator and self check-in. Surrounded by restaurants, transportation, and tourist sites. Your ideal base to explore the city!
Popular amenities for Panama City apartment rentals
Weekly apartment rentals

5B • 5 Bedroom Apt • 4 Baths • Great for Groups

Luxury Centric 2BR Apartment in Casco Viejo

Unique Luxury 3-story Loft at the Yoo

Live the Wanders And Yoo Experience in Panama

PH Yoo 44i – Ocean View Apartment

Luxury Oceanfront Resort 22nd Floor View, 200°

Casa del Horno | A Piece of Panamanian History

The Sands Modern Oceanfront Apartment Panama City!
Private apartment rentals

Panama City Ocean View

Casa Esmeralda Refined 120 m² Duplex in Casco Viejo

City center apartment with pool and ocean view

Ocean View Suite Coastal Strip

Old Town & Ocean View

Panoramic Casco Viejo Lookout in The Sands

Rooftop Pool • Centric • Metro 5 min • Parking

Suite Luxury 30th View Yoo Panamá & Arts Tower
Apartment rentals with a hot tub

Tropical Paradise at Playa Bonita

• Chic • Balcony•Pool Gym•Near Multiplaza•

PH The Gray | Balcony Views · Pool · Gym

Ocean View + Infinity Pool | The Sands

Luxury 2BR Suite with Pool & Views

Ocean View | Infinity pool | Balbia Ave Apt

Luxurious apartment in Marbella

Beautiful colonial condo with a hot tub and balcony
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- Things to do Panama
- Landmarks Panama
- Food tours Panama
- Tastings Panama
- Wildlife Panama
- Outdoors Panama
- Cultural tours Panama
- Cooking Panama







