Guesthouse holiday rentals in Panama City

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Top-rated Guesthouses in Panama City

Guests agree: These guesthouses are highly rated for location, cleanliness and more.

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Guest favourite

Guesthouse in Panamá

4.76 out of 5 average rating, 242 reviews

Garden Cottage in city center

Cozy Private Cottage in Panama City Enjoy a comfortable stay in this charming garden cottage located in a central area of Panama City. With a private entrance, garden, and outdoor barbecue area, you'll have everything you need for a perfect getaway. The property features WiFi, smart TV, air conditioning, a double bed, and a sofa bed in the living room, as well as a fully equipped kitchen and bathroom. It also includes a washer and dryer for your convenience Perfect for an unforgettable escape

Guesthouse in Panamá

4.8 out of 5 average rating, 85 reviews

Cool Guesthouse+WiFi+Pool+Tv+AC @Canal de Panama

✔️SuperAnfitrion Verificado! Tu estadía estará en las mejores manos Casa de huespedes, Cerca al Ciudad del Saber 🇵🇦 📍 En el bosque tropical de la antigua base de Clayton, con comodidades, parques, deportes y gastronomía. Cerca de la ciudad, centros comerciales, las Esclusas de Miraflores y el ferrocarril transoceánico🇵🇦 Ofrecemos: 💧 Agua Caliente 📶 Wifi ❄️ AC 🏊‍♂️ Piscina 📺 Tv Smart y Cable 🚗Parqueadero Esta localización estratégica, con un alto nivel de seguridad en el área.

Guest favourite

Guesthouse in Veracruz

4.94 out of 5 average rating, 17 reviews

2 chambres dans jardin tropical

Dormir au calme entouré de végétation luxuriante à 20 minutes de panama logement spacieux adapté à 2 couple ou famille de 4 personnes 1 lit Queen et 2 twins avec chacun salle de bains privée attenante , mise à disposition d’un lit parapluie Salle de repos hamac , salle de repas cuisine équipée, une piscine eau salée pour vous divertir face à l’océan dont vous êtes les seuls utilisateurs entourés d’un grand jardin Espace de travail avec Wifi rapide Sports nautiques, randonnées à proximité

Guest favourite

Guesthouse in Panamá

4.92 out of 5 average rating, 36 reviews

Home Harmony 15 min. Aeropuerto.

"Experimenta una estancia cómoda y conveniente en nuestro acogedor apartamento, ubicado a solo 10 minutos del aeropuerto Tocumen. Equipado con todas las comodidades necesarias para tu descanso, desde conexión WiFi hasta una cocina equipada, este espacio te ofrece la oportunidad de relajarte y recargar energías. Disfruta del confort del aire acondicionado, agua caliente/fria en el baño, una cama y sofá cama para tu comodidad, televisión con cable , y toallas y sobrecama para tu conveniencia.

Guesthouse in Panama City

4.73 out of 5 average rating, 83 reviews

Efficiency Bungalow - Metropolitan Natural Park

Casita Curundu is located in a quiet and beautiful neighborhood next to the Metropolitan Natural Park. A naturalist delight right in the city, surrounded by an urban jungle forest teeming with birds and wildlife. An amazing place for a couple to stay - you’ll have all the privacy you need but still be close to all the great attractions and the large shopping and transportation hub Albrook Mall, Airport, Bus & Metro Station and yet removed from the hustle and bustle of the city.

Superhost

Guesthouse in Panamá

Trendy Tiny Apartment in Ancon

Nestled in the former Canal Zone, this cozy apartment offers comfort, nature, and city access. Near the City of Knowledge, The Panama Canal and Albrook, it’s perfect for exploring history and culture. We proudly welcome LGBTQ+ travelers and allies to a safe, inclusive space where you can relax and feel at home. Whether you're a solo traveler, a couple, or a digital nomad, you’ll find a warm, affirming environment here. Enjoy tropical hikes, city views, and local events. 🌈

Superhost

Guesthouse in Panamá

4.75 out of 5 average rating, 4 reviews

The Black Studio near airport & city

This unique PRIVATE place has a style all its own. This stylish place is anything but ordinary. It is affordable and its perfect for a couple or business trips. Conveniently located next to shopping malls and supermarkets you’re literally 3 minutes from the train station and just 20 minutes to the city. Don Bosco is a safe place. Enjoy a cozy place with everything you can need for your stay. This place is private with its private entrance. IT IS NOT SHARED!

Guest favourite

Guesthouse in El Cangrejo

4.88 out of 5 average rating, 17 reviews

Charming Urban Retreat with Private Green Oasis

A peaceful, art-filled retreat in the heart of El Cangrejo. This ground-floor apartment features a private green yard — perfect for relaxing or spotting hummingbirds. There is an outdoor furniture dining set (available upon request). Steps from cafés, galleries, parks, and nightlife, yet quiet and tucked away. Only one neighbor on site. Thoughtfully decorated with pieces from local artisans. Watch the video: “El Cangrejo – Unique Oasis Apartment” on YouTube.

Guest favourite

Guesthouse in Balboa

4.87 out of 5 average rating, 53 reviews

Casa de huésped privada en Ancón

Disfruta de la sencillez de este acogedor alojamiento tranquilo y céntrico. Cerca de lugares de interés como el edificio de la Administración del Canal de Panamá, Amador Causeway, Albrook Mall, y varios restaurantes. Personalmente decorado para proporcionar comodidad... grandes ventanales en el dormitorio proporcionan iluminación natural y una vista del jardín y el área verde a través de las ventanas; aun así mantiene la privacidad y la tranquilidad deseada.

Superhost

Guesthouse in Panamá

4.47 out of 5 average rating, 15 reviews

Conveniente Suite céntrica y con estacionamiento

This special place is close to everything, making it easy to plan your visit. 5-10 minutes to any attraction in Panama City. Assigned parking and two blocks from major bus stop that can take you anywhere in the city or accross the country. You will have the entire place for yourself with independent entry, air conditioning and kitchen. There are four grocery stores walking distance. You can exercise daily at a park located behind the property.

Guest favourite

Guesthouse in Panamá

4.93 out of 5 average rating, 42 reviews

CASA PINO, bosque en la ciudad

Excelente Aparta-estudio independiente con todo lo necesario, Baño Privado, Cocineta Nevera y WIFI. Con mucha seguridad. Pueden utilizar máquinas en el parque para hacer ejercicios. Estamos ubicados en un área privilegiada en las revieras del Canal, con mucha vegetación y bosques, pero muy cerca de todas las amenidades recreativas de la Ciudad del Saber. Muy céntrico, a 10 minutos en metro-bus hasta Albrook Mall, a 10 minutos del Canal de Panamá.

Guest favourite

Guesthouse in Distrito San Miguelito, Brisas del Golf, Panama City

5 out of 5 average rating, 26 reviews

Apartamento en área residencial segura

Estarás cerca de todo cuando te quedes en este alojamiento céntrico. Alrededor de 20 minutos del aeropuerto de Tocumen, 15minutos de Estadio Romel, de paso para Zona Libre Colón cerca de comercios, restaurantes, farmacias, supermercados, cines, facilidad de transporte. Si el viaje es de trabajo, de turista, o en tránsito por Panamá en este apartamento podrás estar con comodidad. Estamos a su disposición si requiere información adicional.