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Hotels in Panama City

Find and book unique hotels on Airbnb

Top-rated hotels in Panama City

Guests agree: These hotels are highly rated for location, cleanliness and more.

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Guest favourite
An entrance area is framed by a modern black shelving unit displaying lush green plants. Vintage-style light bulbs hang from the ceiling, providing soft illumination. A tiled floor features intricate geometric patterns, while a staircase is visible in the background, leading to the upper levels.
Hotel room in Panamá
4.7 out of 5 average rating, 134 reviews

Panamá Centro - Habitación con baño privado

Somos un alojamiento inaugurado en Octubre del 2020 ubicado en el centro de la Ciudad de Panamá. Tenemos varios tipos de habitaciones, en este caso, se trata de habitación con 1 cama doble. Ofrecemos servicio de recepción continuo, Wifi de alta velocidad, área de trabajo compartida, sala con máquina expendedora de snacks y café y seguridad las 24 horas. Nuestras habitaciones están totalmente equipadas con baño privado con agua caliente, escritorio, aire acondicionado y televisión por cable.

Guest favourite
A spacious living area features a comfortable sectional sofa, complemented by decorative throw pillows. A glass coffee table holds magazines, while two elegant chairs invite relaxation. Large windows with flowing drapes provide natural light, enhancing the warm, inviting ambiance.
Hotel room in San Felipe
5 out of 5 average rating, 34 reviews

4. Heart of the Old Town: Boutique Apart-Hotel

La Isabela Suites is a Boutique apart-hotel built on the concept of space, elegance and comfort. Located in the heart of Casco Antiguo, only steps from culture, markets, dining, and bars, and with a unique quality of service. La Isabela Suites offers an alternative type of travel, away from the small, standardized and impersonal massive hotel rooms without the inconvenience of a self-catering apartment. Because we understand that the true luxury means not having to worry about anything.

A three-level villa is shown, featuring a bright yellow exterior with blue roofing. Large windows allow natural light to fill the space. Surrounded by lush greenery and tropical plants, a driveway with a vehicle is visible, enhancing the property’s inviting atmosphere.
Casa particular in Panamá

La Husseyenda- Birdwatcher Haven

A Birdwatcher’s and Jungle Paradise nestled in Los Altos de Cerro Azul, this 3-level villa offers breathtaking Lake Alajuela views, stunning sunsets, and endless birdwatching opportunities! Spot hummingbirds, tanagers & toucans from the terrace while howler monkeys call in the distance. Family & pet-friendly with a fenced garden, spacious BBQ, & a fully equipped kitchen. Relax in nature’s paradise—your jungle escape awaits! Make some memories at this unique and family-friendly place.

Superhost
A spacious room features a king bed with soft white linens and colorful striped accent pillows. The headboard is constructed from light wood, complementing the contemporary design. A view of the city skyline is visible in the artwork above the bed, enhancing the room's ambiance.
Hotel room in Panamá
4.75 out of 5 average rating, 12 reviews

Very Nice Downtown Panamá Hotel Free Parking

Welcome to the beautiful Aloft Panamá hotel This is a very nice and safe hotel located in the San Francisco area of Panamá with beautiful city views. King or 2 queen based on availability (Feel free to make request prior to booking if you have a preference) All rooms non smoking ($350 fine) No pets allowed Must be 21 with id to checkin Must have credit card for incidentals Checkin time starts at 3pm Checkout time before noon Free Parking Pool Bar/Lounge

A cozy hotel room is showcased with a spacious bed dressed in white linens and a red throw blanket. A wooden desk with two cups and a remote is positioned beside the bed. A soft lamp and a wall-mounted TV complete the inviting atmosphere.
Hotel room in El Cangrejo
4.74 out of 5 average rating, 34 reviews

Cuarto de hotel #3 a una cuadra del Metro.

Disfruta de acceso ràpido a los destinos más populares de Ciudad de Panamà, centros comerciales, restaurantes, y áreas turísticas. Cuarto de hotel con baño privado, aire acondicionado, cable TV, recepciòn con 24 horas de servicio y estacionamientos sujetos a disponibilidad. Cerca de restaurantes y casinos. A una cuadra de la estaciòn del Metro que lo lleva en 10 minutos a Albrook Mall, el Centro Comercial más grande de Panamà.

Guest favourite
A close-up view of vibrant purple bougainvillea flowers is presented alongside a well-maintained pathway, leading to a charming building with arched windows and a wooden front door. Green foliage frames the entrance, enhancing the welcoming atmosphere.
Hotel room in Panamá
4.86 out of 5 average rating, 44 reviews

Habitaciones privadas Sofia's B&B Hostal Boutique

Alojamiento tipo hostal boutique, contamos con 7 cómodas habitaciones privadas con baño, para una capacidad total de 18 huéspedes. La tarifa mostrada por Airbnb para tu reserva distribuye 2 huéspedes por habitación, es decir, los huéspedes deberan compartir camas y/o habitaciones. Si requieres una distribución especial de habitaciones para tu grupo, contacta primero con el anfitrión, ya que la tarifa podría variar.

Guest favourite
A cozy sleeping area features a plush bed with a light-colored quilt and dotted pillows. A bedside table holds a small lamp, providing soft lighting. The wall is adorned with a unique decorative panel, and a ceiling fan offers comfort.
Private room in Panamá
4.83 out of 5 average rating, 24 reviews

Desk & Dream Room in flat for work and rest

Disfruta de la comodidad de este alojamiento tranquilo y céntrico en el corazón de San Francisco, tiene escritorio dentro de la habitación para trabajar o estudiar en un ambiente relax, con las demás comodidades incluyendo televisor led HD de 32" Justo en la calle de al lado está el super mercado, farmacia al frente, restaurantes, tiendas de chinitos, panaderías, paradas del metro bus cercanas.

An outdoor swimming pool is situated on a rooftop terrace, surrounded by lounge chairs. The skyline of Panama City serves as a backdrop, illuminated by soft twilight hues. Palm plants are placed in decorative pots along the pool's edge, enhancing the space.
Hotel room in Obarrio
5 out of 5 average rating, 3 reviews

Marinn Place | Deluxe King | Cozy Work & Rest

Located in Panama City’s upscale Financial District near Via España and Bella Vista, Marinn Place offers modern comfort, a rooftop pool, and free valet parking in a vibrant urban setting. The spacious Deluxe Double features two plush queen beds, a separate living/sleeping area with a sofa bed, a work desk, and a walk-in glass shower—perfect for families or professionals.

Guest favourite
Large green doors open to a charming balcony, revealing a view of a red-tiled roof and a small table with two chairs. A soft sofa is positioned nearby, complementing the inviting atmosphere of the space.
Hotel room in Panamá
4.84 out of 5 average rating, 111 reviews

Corcho rooms #2 - king room with balconies

Enjoy charming “Corcho rooms” in the heart of touristic Casco Viejo district of Panama City. We carefully restored old colonial building and converted it to the restaurant an serviced guest rooms upstairs. “Corcho” is luckily situated in the central, restored part of Casco. Most of the building around are restored and the neighborhood is safe.

A comfortable sleeping area features a spacious bed dressed in neutral tones. Wooden headboards are complemented by bedside lamps. Natural light filters in through a large window, covered by light, flowing curtains. A small nightstand is positioned on each side of the bed.
Hotel room in Panamá
4.68 out of 5 average rating, 122 reviews

Tu segundo hogar en Panamá.

Nuestras habitaciones están ubicadas en una zona privilegiada en el corazón del sector Financiero y Bancario de la ciudad. Tenemos a dos cuadras de distancia, dos estaciones del sistema de transporte Metro. 15 minutos de algunos Centros Comerciales.

Guest favourite
A spacious private room features a comfortable bed covered with a soft blanket and neatly arranged towels. Two windows allow natural light to enter, while a ceiling fan provides airflow. A closet offers storage, and the neutral colors create a calming environment.
Private room in Marbella
4.9 out of 5 average rating, 59 reviews

Spacious and lovely room meters from the sea - Ztz

Lovely spacious private room with a new brand bed, with great lightning and a workspace inside it. Shared bathroom. Shared kitchen with your private kitchenware and utensils needed to cook. Shared laundry room, with a washing machine

Superhost
Hotel room in Marbella

The Corner Suite #110 | La Résidence Panamá

Contemporary comfort for the modern traveler. This 35–37 m² suite features a king-size bed, full kitchen, washer/dryer, Coffe machine, and A/C — designed with thoughtful touches to make you feel at home.

Popular amenities for Panama City hotels

Quick stats about hotel rentals in Panama City

  • Total holiday rentals

    Explore 130 holiday rentals in Panama City

  • Nightly prices starting at

    Panama City holiday rentals start at $18 NZD per night before taxes and fees

  • Verified guest reviews

    Over 3,620 verified reviews to help you choose

  • Family-friendly holiday rentals

    10 properties offer extra space and kid-friendly amenities

  • Pet-friendly accommodation

    Find 20 rentals that welcome pets

  • Holiday rentals with a pool

    30 properties feature pools

  • Rentals with dedicated workspaces

    90 properties have a dedicated workspace

  • Wi-Fi availability

    120 of Panama City holiday rentals include Wi-Fi access

  • Popular amenities for guests

    Guests love Kitchen, Wi-Fi and Pool across Panama City rentals

  • Nearby attractions

    Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)

Destinations to explore

  1. Airbnb
  2. Panama
  3. Panamá Province
  4. Panama City
  5. Hotel rentals