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Holiday houses in Panama City

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Top-rated holiday rentals in Panama City

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top Guest favourite
A modern living area features a light-colored sofa adorned with colorful cushions. A round coffee table sits on a textured rug, while a dining table for six is visible in the background. Large windows present striking views of the city skyline.
Apartment in Panama City
5 out of 5 average rating, 37 reviews

Luxury apt in Panama City 2 Rooms 3 Baths

El edificio Wanders by yoo esta ubicado en el corazón de la ciudad, es un proyecto fuera de serie donde cada rincón tiene una historia que contar. Recepción 24/7, muchas areas de esparcimiento, estación de hidratación. En las afueras del lobby tenemos la Cafetería cafe con teclas y un restaurante de Carnes Popino. En el area social servicio de barra en la piscinas, parque de niños, sala de juegos con pantallas en e l techo baños, salon de eventos, cocina para eventos, gym full equipado y más

Superhost
A cozy living area features a comfortable blue sofa against an original brick wall, complemented by a round mirror. A small kitchen area with white cabinetry and modern appliances is visible. A decorative coffee table and elegant chairs complete the inviting space.
Apartment in Panamá
4.81 out of 5 average rating, 156 reviews

The Penthouse Annex

Inspired by Panama's rich history with France and located in one of the oldest watch towers in Panama, this chic apartment combines original features of this historically important building with the elegance and style of Europe. Perfectly situated to indulge in the restaurants, cafes, museums and boutique stores of Casco Viejo, and equipped with everything you expect from a home-from-home base, the annex is the perfect combination of comfort and style for couples and small groups of friends.

Superhost
Apartment in Panamá
5 out of 5 average rating, 3 reviews

Acogedor apartamento frente al mar.

Este lugar es único, tiene su propio estilo. Su ubicación es estratégica, será muy fácil llegar. Se encuentra ubicado junto a la Cinta Costera, cerca de la estación del metro, Casco Antiguo, y todos los centros turísticos que Panamá te brinda. Ven y disfruta de esta hermosa experiencia en uno de los mejores edificios de Panamá, el cual te ofrece tranquilidad, entretenimiento, gastronomía, coctelería, historia de Panamá, vistas impresionantes, todo esto dentro del mismo Edificio. ¡Visítanos!

Top Guest favourite
A modern living area features a comfortable sofa, a dining table with chairs, and a fully equipped kitchen. Large windows allow natural light to brighten the space, showcasing views of the city skyline. The decor is minimalistic, with potted plants adding a touch of greenery.
Apartment in Panamá
5 out of 5 average rating, 24 reviews

Moderno y Céntrico· Bonito Condo en Corazón de Pty

¡Moderno apartamento de 50 m2 ubicado sobre Calle 50, en el corazón de la ciudad de Panamá!. Con acceso a lo mejor en arte, cultura, negocios, finanzas, deportes, compras, gastronomía y vida nocturna. * El espacio cuenta con habitación con cama tamaño queen, baño completo, smart TV y escritorio con monitor (cable HDMI) para los que viajan sin desconectar del trabajo. * La sala cuenta con un cómodo sofa cama, baño completo, comedor y, cocina equipada para los amantes de la cocina!.

Top Guest favourite
A communal rooftop space is revealed, showcasing several white-accented chairs and small tables arranged amidst potted plants. The backdrop features a panoramic view of the Panama City skyline against a clear blue sky.
Apartment in Panamá
5 out of 5 average rating, 52 reviews

Tropicool Loft w/rooftop steps from Casco

This historic 1941 loft is located at the entrance of Casco Viejo where you’re steps from the fish market and all the cool cafés, rooftops, and trendy restaurants that make up the neighborhood. Fully equipped kitchen, washer/dryer combo, 1.5 bath, bedroom on 2nd floor, 2 balconies + communal rooftop, projector w/Netflix, fast internet, and great AC. You’re also directly in front of the Cinta Costera park for running, biking, tennis courts. Near local airport for flights to Bocas!

Guest favourite
A cozy bedroom is featured, showcasing a spacious bed adorned with decorative pillows and a soft throw. Large windows offer a view of the city skyline, while modern artwork adds a touch of color to the walls. A wardrobe is positioned against one side.
Condo in Panama City
4.9 out of 5 average rating, 113 reviews

Central, comfortable studio with bay view

Enjoy a stay in the Center of Panama City! Small, equipped and comfortable studio on Av. Centro de España with 42nd Street in Bella Vista, ideal for one or two travelers. Steps from the Santo Tomás Metro station. A 5-minute walk from the Cinta Costera going down, Parque Urracá, Supermarket Rey and Riba Smith, Zona Bancaria (Calle 50), Calle Uruguay (restaurant area), 15 minutes by car from the Old Town and more. Enjoy the different amenities we offer you!

Guest favourite
A spacious living area features a combination of modern and vintage furnishings. A large turquoise sofa and a floral chaise lounge are complemented by a round coffee table and a green wooden chair. Exposed stone walls and large windows with blue accents create a warm ambiance.
Apartment in Panamá
4.98 out of 5 average rating, 148 reviews

Escápate al Corazón de Casco con Balcón Privado

Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Guest favourite
A modern living area is showcased, featuring a light gray sofa positioned across from a flat-screen TV on a wooden console. Two abstract art pieces adorn the walls. Floor-to-ceiling windows offer views of the city skyline, enhancing natural light in the space.
Condo in Panamá
4.95 out of 5 average rating, 129 reviews

Beautiful Apartment 3 guests

Moderno, elegante y cómodo departamento, cerca de todo! Restaurantes, farmacias, supermercados, canchas de padle, a pocos minutos del centro comercial Multiplaza. Totalmente amoblado, 1 recamara, 1 baño completo, walking closet, cocina, sala, área de desayunador, lavadora-secadora y balcón. Para su disfrute, piscina de agua salada en el último piso, gimnasio, espacio de co-working, incluye un espacio de estacionamiento con valet parking.

Top Guest favourite
An inviting living area is featured, showcasing a modern grey sofa accented with decorative pillows. A round glass dining table is surrounded by chairs, and artistic wall frames complement the space. Natural light is filtered through elegantly layered window shades.
Apartment in Panamá
4.97 out of 5 average rating, 118 reviews

Apartamento de lujo Panamá centro, área bancaria

Contamos con una ubicación estratégica justo sobre la vía principal de Panamá (Calle 50) Bella Vista, te encontraras ubicado en el corazón del área bancaria. Si vienes por trabajo o vacaciones, este es el lugar ideal, encontrarás todo tipo de restaurantes a los alrededores, comercios, centro comerciales, tendrás la Cinta Costera a tan solo 10 minutos a pie donde podrás pasear o ejercitarte. Diversión y disfrute a pocos pasos

Guest favourite
Apartment in Panamá
4.98 out of 5 average rating, 119 reviews

Apartamento completo en Panama

Este encantador apartamento está ubicado en uno de los mejores barrios de Panamá, San Francisco, un lugar céntrico donde encontrarás amplía gastronomía, lugares de diversión, cerca a estaciones de buses, y al centro comercial más importante de la ciudad, Multiplaza. Este apartamento céntrico y tranquilo es una oportunidad que no querrás dejar pasar. Ofrece la combinación perfecta de comodidad, belleza y ubicación conveniente.

Top Guest favourite
A well-lit bedroom features a spacious bed with light-colored bedding, complemented by decorative wall art. Natural light enters through large glass doors, which open to a small terrace with greenery. A cozy armchair is positioned nearby, enhancing the room's inviting atmosphere.
Condo in Panamá
5 out of 5 average rating, 13 reviews

King Bed, Creative Design Steps from Casco Viejo

Casco 114 is a stay created by travelers, for travelers. Located in the heart of Santa Ana, the creative district of Panama’s Casco viejo, it offers a king bed, full-size trundle, sofa bed, private terrace, washer/dryer, and unique decor. At PH Casco View: enjoy a saltwater pool, coworking space, stunning views of both the Old Town and the modern city, paid parking, and all the comforts for an unforgettable stay.

Guest favourite
A private terrace features a jacuzzi surrounded by lush greenery against an exposed stone wall. Wooden decking creates a warm ambiance, complemented by two lounge chairs designed for relaxation, offering an inviting outdoor space for guests.
Apartment in Panama City
4.9 out of 5 average rating, 153 reviews

Jacuzzi in colonial ruins in beautiful apartment

Welcome to Casa Marquez Portazgo! This cozy apartment in the heart of Panama City offers comfort and convenience, ideal for your stay. With one bedroom and capacity for two people, you'll enjoy a relaxing atmosphere in 70 m². Located in the San Felipe neighborhood, just steps from the entrance to the Casco Antiguo, it offers a unique experience. You can also unwind in the jacuzzi.

Popular amenities for Panama City holiday rentals

Quick stats about holiday rentals in Panama City

  • Total holiday rentals

    Explore 4,740 holiday rentals in Panama City

  • Nightly prices starting at

    Panama City holiday rentals start at $17 NZD per night before taxes and fees

  • Verified guest reviews

    Over 114,280 verified reviews to help you choose

  • Family-friendly holiday rentals

    1,480 properties offer extra space and kid-friendly amenities

  • Pet-friendly accommodation

    Find 1,680 rentals that welcome pets

  • Holiday rentals with a pool

    2,570 properties feature pools

  • Rentals with dedicated workspaces

    2,880 properties have a dedicated workspace

  • Wi-Fi availability

    4,490 of Panama City holiday rentals include Wi-Fi access

  • Popular amenities for guests

    Guests love Gym, BBQ grill and Laptop-friendly workspace across Panama City rentals

  • 4.7 Average rating

    Panama City stays receive an average rating of 4.7 out of 5 from guests

  • Nearby attractions

    Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)

Destinations to explore

  1. Airbnb
  2. Panama
  3. Panamá Province
  4. Panama City