Hotels in Upstate South Carolina

Find and book unique hotels on Airbnb

Top-rated hotels in Upstate South Carolina

Guests agree: these hotels are highly rated for location, cleanliness and more.

1 of 1 pages1 / 1

Guest favourite

A cozy interior space is showcased with natural wood paneling. A spiral staircase leads to an upper level. A modern kitchen with bar seating features a sleek countertop and contemporary appliances. Soft seating is provided by a light-colored sofa, inviting relaxation.

Hotel room in Cashiers

4.96 out of 5 average rating, 121 reviews

Log Suite at our Boutique Bed & Brewery

Our Two-Story log suites are the perfect basecamp for couples and families alike. They offer two bedrooms with two spacious bathrooms, along with a small kitchen, equipped with induction cook top and refrigerator. Great for extended weekends or a quick trip to enjoy the beauty of Cashiers, North Carolina. Be sure to take a quick hike over to our on-site brewery, Whiteside Brewing Co., and enjoy the great food and drink selection they have to offer. This suite is sure to cure what “ales” you! ;)

Superhost

An outdoor heated pool is surrounded by lush green mountains and trees. Bright green lounge chairs sit beside the pool, providing a space for relaxation. The sky is mostly clear with scattered clouds, enhancing the serene atmosphere of the setting.

Hotel room in Ashville

4.78 out of 5 average rating, 64 reviews

Asheville Escape | Free Parking & Pet-Friendly

Experience Asheville’s charm at Holiday Inn Asheville East-Blue Ridge Parkway, a pet-friendly mountain lodge hotel perfectly situated near Biltmore Estate and the Blue Ridge Parkway. Enjoy an on-site dining at Woodfire Grille & Bar and modern amenities like free WiFi, EV chargers, and a fitness center. Explore attractions, hiking trails, and scenic views, all just minutes away. Perfect for families, pets, and tour groups, offering comfort and convenience in a prime location.

Superhost

A spacious room is depicted, featuring a king bed with crisp white linens. Dark blue walls are complemented by framed artwork. A large TV is mounted on the wall, and a seating area is visible. A closet and mini-fridge are arranged in the corner.

Hotel room in Clayton

5 out of 5 average rating, 7 reviews

King Room at Bridge Creek Inn

Settle into comfort in our Standard King Room at Bridge Creek Inn—perfect for solo travelers or couples. This stylish room features a plush king bed, smart TV, mini-fridge, and a modern bathroom with a walk-in shower. Natural light fills the space, creating a warm and relaxing atmosphere. Enjoy high-speed Wi-Fi and a cozy layout ideal for work or rest. Don’t miss Vandiver, our onsite restaurant and bar, serving up Southern-inspired cuisine and craft cocktails daily.

Guest favourite

A spacious bedroom features a king-sized bed with an ornate wooden headboard and matching posts. A lighted ceiling fan circulates air, while a television is mounted on the wall. Natural light streams through the plantation shutters, enhancing the neutral-toned walls.

Hotel room in Lake Lure

5 out of 5 average rating, 5 reviews

Swayze Suite at Lake Lure Inn

Experience vintage elegance and modern comfort in the Swayze Suite at The Lake Lure Inn and Spa. This luxurious retreat features a king-sized bed, spa-inspired bathroom, and a cozy living area with old Hollywood charm. Guests enjoy access to the inn’s pool, on-site dining, and spa. Explore Lake Lure's scenic beauty and iconic "Dirty Dancing" locations. Perfect for romance or relaxation, this suite offers an unforgettable getaway. Book now for timeless memories!

Guest favourite

Hotel room in Ashville

4.97 out of 5 average rating, 226 reviews

King room with City View at Kimpton!

Stay steps from Asheville’s buzzing breweries, indie art galleries, and live music at Kimpton Hotel Arras. Your room blends boutique flair with luxe linens, spa-inspired bathrooms, and city or Blue Ridge Mountain views. Grab a cocktail at the lobby bar, hop on a complimentary bike to explore downtown, or soak up Asheville’s creative soul with your pup in tow. Warm Southern vibes, walkable adventures, and boutique perks make this the ultimate Asheville escape.

Superhost

A stone exterior leads to a set of stairs adorned with a railing. Lush greenery and vibrant red flowers line the path, creating a natural entrance. The building features large windows and an inviting overhang for shelter.

Hotel room in Whittier

4.92 out of 5 average rating, 60 reviews

The Blue Ridge Suite at the Lodge at Smoky Cove

You won’t want to leave this charming, one-of-a-kind place. The Blue Ridge Suite has a private balcony and entrance or use the main entrance on our grand patio. The suite is equipped with a full kitchen and full size fridge. A beautiful queen log bed and a sleeper sofa bed. Relax in front of the fire in your cute little arm chairs. Enjoy the view from the bed or your private balcony. Enjoy the stocked complimentary coffee bar in the Great Room.

Superhost

A spacious king suite is showcased with natural wood paneling. The room includes large windows allowing soft light, a king bed adorned with layered linens, and a cozy seating area featuring a leather sofa and a woven chair. A vintage typewriter sits atop a green desk.

Hotel room in Highlands

5 out of 5 average rating, 3 reviews

Outpost Inn Highlands

Room 6 is an inspired King Suite with luxury king bed, Italian linens, gas fireplace, vibey seating area, flatscreen tv, desk with typewriter, hanging closet, minibar with North Carolina goodies, minifridge, coffeemaker, luxury bathroom with robes, luxury toiletries and walk in shower with incredible water pressure! Record players available upon request! You'll feel at home in the mountains while being enveloped in luxury and inspiration!

Superhost

Hotel room in Waynesville

5 out of 5 average rating, 4 reviews

Stylishly Updated Room | Charming Couples Stay

Step into a slower, sweeter way of living at Wildrest Hotel. A 1946 mountain retreat where time stretches, worries fade, and real connection returns. Hidden beneath a canopy of old-growth trees and wrapped in the timeless beauty of stone and timber, this historic property invites you to trade the noise of everyday life for something more meaningful, quiet mornings, long conversations, and the kind of peace you forgot you were missing.

Hotel room in Spartanburg

4.6 out of 5 average rating, 5 reviews

Wyndham Spartanburg | Queen | Kitchen Convenience

Designed for solo travelers or couples on extended assignments, this queen suite provides a kitchenette, desk and plenty of storage. Free Wi‑Fi and a smart HDTV allow you to stay productive and entertained. Step outside to hike in Croft State Park, taste Carolina barbecue downtown or visit historic sites. The hotel’s fitness centre and laundry room add daily ease to a longer stay.

Superhost

Hotel room in Fort Mill

4.81 out of 5 average rating, 265 reviews

Minutes to Charlotte + Pool. Bar & Free Parking

Experience small-town charm just 20 miles from Uptown Charlotte at Cambria Hotel Fort Mill. Located near I-77, we’re just 2 miles from Baxter Town Center and 10 minutes from Carowinds. Enjoy modern amenities including a seasonal outdoor pool, 24/7 fitness center, on-site dining, and tech-forward rooms with Bluetooth mirrors, perfect for exploring Fort Mill and greater Charlotte.

Guest favourite

A cozy bedroom features a spacious bed adorned with soft linens. Two large windows with sheer white curtains provide natural light. Two plush armchairs are placed in front of a garden view, with a decorative mirror reflecting the inviting ambiance.

Hotel room in Black Mountain

5 out of 5 average rating, 11 reviews

Mountain views @ Boutique Hotel

1936 Georgian-Revival, turned Coffee + Cocktail Bar, Housing NC's Smallest Boutique Hotel. This moody, color-drenched studio offers a private balcony with mountain views. Please note: the coffee/bar is open to the public and there is potential for noise. The bar closes at 9pm on weekdays and 10pm on Fri/Sat. Hotel is suggested adults only (21+)

Guest favourite

A spacious room features a large bed with soft bedding and a decorative pillow. A comfortable sofa is positioned in front of the bed. A dining area with a round table and chairs is visible, along with a kitchenette in the background.

Hotel room in Clemson

5 out of 5 average rating, 58 reviews

The Abernathy

The Abernathy is located one block from The Rock and offers guests large rooms with 445 sq. ft. to stretch out and enjoy their stay in Clemson. Bicycles are available for guests to take on a leisurely pedal through Clemson's campus at their own pace. There is also an on-site bar to enjoy after a long day of exploring.