Hotels in Upstate South Carolina

Find and book unique hotels on Airbnb

Top-rated hotels in Upstate South Carolina

Guests agree: these hotels are highly rated for location, cleanliness and more.

%{current} / %{total}1 / 1
Guest favourite
A cozy interior space is showcased with natural wood paneling. A spiral staircase leads to an upper level. A modern kitchen with bar seating features a sleek countertop and contemporary appliances. Soft seating is provided by a light-colored sofa, inviting relaxation.
Hotel room in Cashiers
4.96 out of 5 average rating, 109 reviews

Log Suite at our Boutique Bed & Brewery

Our Two-Story log suites are the perfect basecamp for couples and families alike. They offer two bedrooms with two spacious bathrooms, along with a small kitchen, equipped with induction cook top and refrigerator. Great for extended weekends or a quick trip to enjoy the beauty of Cashiers, North Carolina. Be sure to take a quick hike over to our on-site brewery, Whiteside Brewing Co., and enjoy the great food and drink selection they have to offer. This suite is sure to cure what “ales” you! ;)

Guest favourite
A stylish bedroom features a wooden bed frame adorned with a striped blanket. A vintage typewriter rests on a reclaimed wood table, complemented by a modern green desk lamp. A large artwork and a black cabinet are visible in the background, alongside a door that opens to the outside.
Hotel room in Highlands
5 out of 5 average rating, 9 reviews

Outpost Inn Highlands

Rooms 8,9, 10 and 13 offer large hotel rooms where the rustic beauty of the mountains meet the luxury and comfort of a boutique hotel! Enjoy gas fireplaces, luxury mattresses, Italian linens, Walnut headboards, Appalachian Textiles and Pendleton blankets, flat screen TV, Minibar, Minifridge, coffeemaker and special touches like vintage typewriters and record players upon request. Enoy our beautiful bathrooms with robes, luxury toiletries and incredible water pressure in our walk-in showers.

Guest favourite
A spacious bedroom features a tall tufted headboard above a well-dressed bed, complemented by a soft area rug. Large windows allow natural light to fill the room, while elegant drapes frame the view. A chandelier hangs from the ceiling, adding a touch of sophistication.
Hotel room in Newton
5 out of 5 average rating, 10 reviews

Boutique Hotel: The Princess Bride Suite

The princess bride quarter is your romantic honeymoon suite. This natural light infused room is a large master suite overlooking the back gardens and ceremony site for weddings. A truly romantic room that evokes a modern Parisian style room. 300 square feet of luxury with spa-like walk-in shower. Slip into our monogram Boutique Auberge robe and luxuriate in an intoxicating scent from our keepsake soap made exclusively for Boutique Auberge. Hot breakfast included upon request.

Guest favourite
The room features two spacious queen beds with cushioned headboards and bedside lighting. The stylish decor includes a geometric patterned wall design and modern furnishings, complemented by hardwood flooring. A ceiling fan is positioned overhead for added comfort.
Hotel room in Hendersonville
4.95 out of 5 average rating, 19 reviews

Renovated Double Queen Stay

Experience serene beauty at CedarWood Inn. Your comfortable haven features modern amenities blended with a comforting touch, promising a restorative stay. Discover the perfect balance of contemporary design and inviting homely details. With quick WiFi and a Roku Smart TV, your stay here is both relaxing and convenient. Ideal for exploring golf courses, orchards, wineries, the Flat Rock Playhouse, and a host of nearby attractions. Your ideal base for a rejuvenating escape.

Superhost
Hotel room in Clayton
5 out of 5 average rating, 5 reviews

King Room at Bridge Creek Inn

Settle into comfort in our Standard King Room at Bridge Creek Inn—perfect for solo travelers or couples. This stylish room features a plush king bed, smart TV, mini-fridge, and a modern bathroom with a walk-in shower. Natural light fills the space, creating a warm and relaxing atmosphere. Enjoy high-speed Wi-Fi and a cozy layout ideal for work or rest. Don’t miss Vandiver, our onsite restaurant and bar, serving up Southern-inspired cuisine and craft cocktails daily.

Guest favourite
Hotel room in Ashville
4.97 out of 5 average rating, 205 reviews

King room with City View at Kimpton!

Stay steps from Asheville’s buzzing breweries, indie art galleries, and live music at Kimpton Hotel Arras. Your room blends boutique flair with luxe linens, spa-inspired bathrooms, and city or Blue Ridge Mountain views. Grab a cocktail at the lobby bar, hop on a complimentary bike to explore downtown, or soak up Asheville’s creative soul with your pup in tow. Warm Southern vibes, walkable adventures, and boutique perks make this the ultimate Asheville escape.

Superhost
A stone exterior leads to a set of stairs adorned with a railing. Lush greenery and vibrant red flowers line the path, creating a natural entrance. The building features large windows and an inviting overhang for shelter.
Hotel room in Whittier
4.92 out of 5 average rating, 60 reviews

The Blue Ridge Suite at the Lodge at Smoky Cove

You won’t want to leave this charming, one-of-a-kind place. The Blue Ridge Suite has a private balcony and entrance or use the main entrance on our grand patio. The suite is equipped with a full kitchen and full size fridge. A beautiful queen log bed and a sleeper sofa bed. Relax in front of the fire in your cute little arm chairs. Enjoy the view from the bed or your private balcony. Enjoy the stocked complimentary coffee bar in the Great Room.

Superhost
A spacious studio is showcased, featuring a king bed with crisp linens. A flat-screen TV is mounted on the wall opposite a small sitting area with a gray chair. A fully equipped kitchen is visible, including a microwave and stovetop. A bathroom with glass doors is also present.
Hotel room in Ashville
5 out of 5 average rating, 11 reviews

Pet Friendly, Outdoor Grills & Gym Access

Make yourself at home at TownePlace Suites Asheville Downtown, where comfort meets convenience. Nestled just minutes from the stunning Carolina National Parks and right in the heart of Asheville’s vibrant scene, our hotel places you steps from renowned restaurants, local breweries, and cultural hotspots. Enjoy inviting outdoor spaces with a fireplace and grills—perfect for relaxing after a day of adventure.

Guest favourite
The exterior of the boutique hotel features a multi-level structure with a dark facade, large windows, and a covered porch lined with wooden railings. Lush greenery, stone pathways, and landscaped areas are visible, enhancing the inviting atmosphere of the property.
Hotel room in Black Mountain
4.86 out of 5 average rating, 7 reviews

Boutique Mountain Retreat

One of six distinct Suite at Peri Social House, NC's Smallest Boutique Hotel. Walk to Downtown Black Mountain, Asheville's BEST neighboring mountain town, and enjoy the wide array of Art Galleries, Eateries, and quaint mountain views. The Holman Suite is located on the second stairs above a 1936 Summer Home, turned Boutique Hotel, which houses a Public Coffee Shop + Craft Beer/Wine Bar Downstairs.

Guest favourite
Hotel room in Waynesville
4.88 out of 5 average rating, 76 reviews

Cozy Updated Stay • Perfect for Couples Getaway

Just 25 minutes from Cataloochee Ski Area, The Wildrest feels like stepping into the winter version of a childhood mountain getaway—the kind where ski days are long and nights are slow and quiet. After carving fresh tracks, come home to warm stone walls, weathered wood, and the soft stillness of mountain life settling in around you. The nostalgia is unmistakable.

Guest favourite
A spacious room features a large bed with soft bedding and a decorative pillow. A comfortable sofa is positioned in front of the bed. A dining area with a round table and chairs is visible, along with a kitchenette in the background.
Hotel room in Clemson
5 out of 5 average rating, 56 reviews

The Abernathy

The Abernathy is located one block from The Rock and offers guests large rooms with 445 sq. ft. to stretch out and enjoy their stay in Clemson. Bicycles are available for guests to take on a leisurely pedal through Clemson's campus at their own pace. There is also an on-site bar to enjoy after a long day of exploring.

Superhost
A spacious hotel room features a king bed with clean white linens and wooden furniture. A large window allows natural light to enter, revealing a shared balcony that overlooks green foliage. A desk and chair are positioned nearby, along with a mirror reflecting the room's layout.
Hotel room in Hendersonville
4.55 out of 5 average rating, 22 reviews

Kanuga Lake Inn - King Shared Balcony

Traditional hotel accommodation that includes a king bed, private bathroom and air conditioning/heating. These rooms feature a shared balcony with the adjacent room that overlooks into a courtyard area or a parking lot. Our hotel rooms do not have a view of the lake. Please note there is not a TV in the room.

Popular amenities for Upstate South Carolina hotels

Destinations to explore