Hotels in Upstate South Carolina

Find and book unique hotels on Airbnb

Top-rated hotels in Upstate South Carolina

Guests agree: these hotels are highly rated for location, cleanliness and more.

%{current} / %{total}1 / 1

Guest favourite

Hotel room in Waynesville

4.91 out of 5 average rating, 47 reviews

Updated Design: Camp Vibes, Fire Pit @ 1940s Inn

NOTE: Select rooms available as we complete renovation to other parts of the property Crunching gravel beneath your tires signals your arrival. As you roll to a stop beneath a canopy of tall hardwoods, the fresh scent of pine and damp earth fills your lungs. Birdsong echoes through the crisp mountain air, and a breeze stirs the scent of woodsmoke and wildflowers. Just ahead, the stone façade of a 1946 mountain lodge emerges from the trees—its timber beams and timeless charm welcoming you home.

Superhost

A cozy room features a wooden ceiling and walls, with a spacious bed adorned with decorative pillows and a comforter. Soft drapes frame a window that opens to a view of the surrounding woods, while a bedside lamp adds a gentle light.

Hotel room in Sylva

4.76 out of 5 average rating, 244 reviews

204 (SMALL R00M) Click on photos for larger room.

The Tahimek Mountain Lodge is located in a secluded, pristine, mountain cove. Surrounded by tall hardwood trees, with views of the sunset and surrounding mountains. A peaceful retreat for guests seeking a quiet place to relax and enjoy nature. This room is cozy, yet small. If you prefer a larger room please click on photos to see other rooms. WiFi Tahimek Password Asheville1954 Check-in instructions provided when booked. If you require assistance please ring doorbell at Office Door.

Superhost

Two glasses of red wine sit on a wooden table, accompanied by a plate of snacks. In the background, a cozy gathering occurs around a firepit, with people enjoying food and each other's company, surrounded by a warm ambiance.

Hotel room in Highlands

4.8 out of 5 average rating, 5 reviews

Outpost Inn Highlands

The Petite is our 170 SF Queen hotel room with all of the bells and whistles of larger rooms but in a cozier footprint- luxury Queen mattress, Italian linens, vintage Appalachian textiles, Pendleton Blankets, coffeemaker, minibar with NC goodies, minifridge, luxury bathroom with robe, luxury toiletries and amazing walk in shower with the best water pressure. Please note this Room has since been painted Hague Blue by Farrow and Ball (pics on the way!). Outside your door is our newest firepit!

Guest favourite

A stone exterior of the lodge is highlighted by a well-maintained pathway lined with vibrant red roses. The building features rustic wooden beams and a covered porch, blending seamlessly with the surrounding greenery.

Private room in Whittier

4.92 out of 5 average rating, 106 reviews

Buffalo Room at The Lodge at Smoky Cove

Nestled in the Western North Carolina Mountains. A hidden gem conveniently located just off Hwy 74 up a paved road. Enjoy the serenity of the Smokies and take in the view from a rocking chair from our front porch. Perfectly situated overlooking GSMNP, a short drive to Blue Ridge Parkway. Amazing waterfall hikes nearby for a novice or advanced hiker. Abundant trout in nearby rivers. The sweet little towns of Sylva, Dillsboro and Bryson City, Cherokee Casino just 10 minutes away.

Superhost

An outdoor heated pool is surrounded by lush green mountains and trees. Bright green lounge chairs sit beside the pool, providing a space for relaxation. The sky is mostly clear with scattered clouds, enhancing the serene atmosphere of the setting.

Hotel room in Ashville

4.8 out of 5 average rating, 40 reviews

Asheville Escape | Free Parking & Pet-Friendly

Experience Asheville’s charm at Holiday Inn Asheville East-Blue Ridge Parkway, a pet-friendly mountain lodge hotel perfectly situated near Biltmore Estate and the Blue Ridge Parkway. Enjoy an on-site dining at Woodfire Grille & Bar and modern amenities like free WiFi, EV chargers, and a fitness center. Explore attractions, hiking trails, and scenic views, all just minutes away. Perfect for families, pets, and tour groups, offering comfort and convenience in a prime location.

Superhost

A spacious room features a large bed with crisp white linens, flanked by modern bedside lamps. Hardwood floors and a textured area rug add warmth. A small desk and chair sit beside a window with blinds, while a potted plant enhances the inviting atmosphere.

Hotel room in Cashiers

4.85 out of 5 average rating, 82 reviews

Boutique Hotel - Premium King Room. Best Location!

Hotel Cashiers is an upscale and conveniently located inn just a brief walk from the center of Cashiers, and a short drive from Lake Glenville, Highlands and Sapphire and nearby attractions in the Blue Ridge and Smoky Mountains. Our newly renovated Luxury King Room is a perfect blend of modern and rustic design. Our Luxury King Rooms feature light oak floors, custom furniture, heavenly bedding and luxurious toiletries. Located in the heart of Cashiers, North Carolina.

Guest favourite

Hotel room in Ashville

4.97 out of 5 average rating, 177 reviews

King room with City View at Kimpton!

Stay steps from Asheville’s buzzing breweries, indie art galleries, and live music at Kimpton Hotel Arras. Your room blends boutique flair with luxe linens, spa-inspired bathrooms, and city or Blue Ridge Mountain views. Grab a cocktail at the lobby bar, hop on a complimentary bike to explore downtown, or soak up Asheville’s creative soul with your pup in tow. Warm Southern vibes, walkable adventures, and boutique perks make this the ultimate Asheville escape.

Guest favourite

A spacious room features a four-poster bed with crisp white bedding and a simple gray throw. Natural light filters through the windows, complemented by soft curtains. A comfortable chair sits nearby, and a small kitchenette area is visible, complete with a beverage cooler.

Hotel room in Cashiers

4.89 out of 5 average rating, 288 reviews

King Room at our Boutique Bed & Brewery

Our King Room, located in the heart of Cashiers, North Carolina, is the perfect base camp for your mountain adventure! Whether you prefer to explore the beauty of the surrounding area or would rather explore a few locally crafted brews from our on-site brewery, Whiteside Brewing Co., we guarantee this room will cure what “ales” you. ;) Come dwell with us!

Guest favourite

A cozy sleeping area features a spacious bed with crisp white linens, complemented by soft cream curtains allowing gentle light to filter in. A bedside table holds a vintage-style lamp, illuminating the corner, while framed artwork adds decorative charm to the space.

Hotel room in Black Mountain

5 out of 5 average rating, 9 reviews

Balcony Studio @ Boutique Hotel

1936 Georgian-Revival, turned Coffee + Cocktail Bar, Housing NC's Smallest Boutique Hotel. This moody, color-drenched studio offers a private balcony with mountain views. Please note: the coffee/bar is open to the public and there is potential for noise. The bar closes at 9pm on weekdays and 10pm on Fri/Sat. Hotel is suggested adults only (21+)

An open-concept living area features a fully equipped kitchen with stainless steel appliances, including an oven and refrigerator. A granite center island provides seating for two. The living space includes a comfortable sofa and a wall-mounted flat-screen TV, enhancing the modern ambiance.

Hotel room in Greer

4.69 out of 5 average rating, 88 reviews

1 BR Double Queen Nightly Rate Furnished APT

500+ Sq. Feet Suites With a Dedicated Living Room, Full Kitchen and Separate Bedroom From enjoying your morning coffee and breakfast in the kitchen to walking down the hall and getting ready for the day in the bedroom and separate bathroom, we’ve created an environment where guests can go about their day as if they were at home and not a hotel.

Guest favourite

A spacious room features a large bed with soft bedding and a decorative pillow. A comfortable sofa is positioned in front of the bed. A dining area with a round table and chairs is visible, along with a kitchenette in the background.

Hotel room in Clemson

5 out of 5 average rating, 54 reviews

The Abernathy

The Abernathy is located one block from The Rock and offers guests large rooms with 445 sq. ft. to stretch out and enjoy their stay in Clemson. Bicycles are available for guests to take on a leisurely pedal through Clemson's campus at their own pace. There is also an on-site bar to enjoy after a long day of exploring.

Superhost

A modern kitchen area features stainless steel appliances, including a stove and microwave, set against a backdrop of dark cabinetry. A granite countertop with two bar stools is situated next to a cozy seating area with a light gray sofa. Wood-like flooring contributes to the contemporary feel.

Hotel room in Greenville

4.78 out of 5 average rating, 218 reviews

Dbl Queen 1 BR, Brand New Hotel, close to shopping

This aparthotel is very close to Haywood Mall in an area rich with a multitude of shopping and dining options. Each suite includes high speed internet, full kitchen equipped with basic pots, pans and dishes. All suites feature a separate bedroom. An exercise facility and guest laundry are located on premises.