
House holiday rentals in Upstate South Carolina
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Top-rated house rentals in Upstate South Carolina
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The Greenville Nest - Retreat & Relaxation Home
This beautifully one-level home offers 3 queen beds and 2 baths, accommodating up to 6 guests. Centrally located in a peaceful neighborhood. 8-minute drive to GSP airport, 15-minute drive to downtown Greenville, minutes from I-85/385, and minutes from Woodruff and Pelham Rd. You'll appreciate the easy access to food delivery and restaurants. Enjoy a stylish Experience for entertaining, working, and relaxing with high-speed Wi-Fi. Quiet and safe with an enjoyable private screened porch and Grill.

Modern Wooded Retreat
Come enjoy this modern, 1.6 acre retreat! Relax with the whole family in a place you'll never want to leave. Located 5 min. to downtown TR and less than 20 min to downtown Greenville! Roast marshmallows by the firepit, play yard jenga, connect 4 and cornhole in the fully fenced, dog friendly back yard. Close to the swamp rabbit trail, and centrally located to lakes, hiking, fishing and exciting nightlife. Let us host you, while you explore everything Greenville and Travelers Rest have to offer.

Modern Scandinavian-Japanese Insp. Mountain Home
This custom home, built in 2020, is the perfect spot to unwind. Located off of a private road (4-wheel drive isn't necessary), it sits on 4.25 acres, w/gorgeous views of the Great Smoky Mountains. Once there, you truly feel removed from the world. Its modern, Scandinavian-Japanese design is unique to the area. Includes: master bedroom, sleeping loft (queen-sized futon and custom Twin XL bunk beds); open kitchen/living area, covered and open patios. 10 minutes from Bryson City and Cherokee.

Happy Place on Rich Mountain
Nestled on a serene mountain ridge. Cozy vibe. Perfect for a single traveler or couple. Listen to the trickling stream as you relax on either covered porch or large deck with pergola.. 15 min drive to DuPont State Recreational Forest or Pisgah National Forest. 10 min drive from downtown Brevard. Fully stocked kitchen, W/D, and coffee bar. Kick back with double reclining sofa or recliner chair. Wifi, Roku TV, and electric fireplace in living room. Transylvania County land of 250+ waterfalls.

Country Cottage~Farm Animals!
Step away from your hustle as you enjoy this cozy, quiet setting in the country. We offer a small kitchen, microwave, toaster, dual coffee maker, fridge/freezer, and two-burner stovetop. You will find a comfy dining/sitting room area. Meander around outside, relax on the porch, or visit our farm animal pets. 20 minutes to Historic Abbeville. Greenwood or Anderson in 30 min. Greenville approx 1 hr. 5 miles: Erskine College 15 min: Diamond Hill Mine Heyward Manor wedding venue: 18 miles

Cabin I Private hiking trails | Hot Tub I Sauna
Welcome to your private mountain escape in Lake Toxaway, NC! This 1-bedroom, 2-bathroom cabin is a one-of-a-kind retreat, offering breathtaking sunset views, a peaceful wooded setting, and unique architectural details. Unwind in the hot tub under the stars, relax in the sauna, challenge your partner to air hockey, or cozy up by the fire pit—all while enjoying the beauty of nature. Plus, enjoy exclusive access to 3 miles of private hiking trails, perfect for exploring the great outdoors!

Orchard Hill Vintage Cottage
Come enjoy this magnificent view in Saluda! Relax in the swings or sit on the porch and enjoy the peacefulness. The fire pit under the stars is so Saludacrous! Our cozy cottage is just steps from Judds Peak and 2 miles from downtown, where there is always food and fun! The Gorge Zipline is located in our quaint little town and the Green River has hiking, tubing, kayaking, white water rafting, rock climbing! The towns of Hendersonville, Flat Rock and Asheville are just minutes away.

Waterfall Views, Lake Hartwell, Highland Architect
Come and enjoy nature with 100+ acres to roam. Architect James Fox designed this cantilevered cliffside home overlooking a beautiful waterfall. Feel like you are in the trees, in an area much as it was when inhabited by Cherokee Indians. Stream feeds into Lake Hartwell. In the summer months on the weekends and holidays kayaks, jet skis and small boats visit the falls. This property is in the foothills of the Appalachian Mountains. Please respect our pet policy, only service animals.

Villa Nirvana, Serene, Secluded, Beautiful Views!
It’s hard to tell where the sky and mountains end and where Villa Nirvana (Heaven) begins in this Mid Century house, composed for serene modern mountain living. Perched at 3000 ft. on an acre of untouched woodlands, Villa Nirvana harmonizes with vibrant nature and the infinite sky outside, with flowing hickory floors, translucent sky blue walls, and sleek wood furniture. Ensconced in an oasis of sophisticated style, gaze at a long range view of the Blue Ridge and Smoky Mountains.

Cozy Treehouse
Situated at the back of a wooded 2 acre lot, only 10 minutes from downtown Greenville, this is a little oasis in the city! While most treehouses take you on a "roughing it" adventure, Cozy Treehouse is the glamping version of treehouses, boasting 9' ceilings, 1.5 baths, 3 LED TV's and many outdoor living options. If you are looking for a unique getaway just minutes from one of the top growing cities in the south, Cozy Treehouse is the perfect destination for you.

Luxury Mountain View Getaway
Cloud 9 isn’t just a place to stay — it’s a place to feel. Elegant. Refined. Rooted in nature. Thoughtfully designed and tucked into the mountains, this soulful retreat offers stillness, beauty, and intention in every detail. It doesn’t compete with the land — it whispers into it. Here, quiet becomes the ultimate amenity. A place that feels like home — and a dream — all at once. Come experience the kind of calm that stays with you. Book your stay at Cloud 9

Villa Rose-On 2 Acres. FP, King Bed, 1mi Biltmore
Chic Modern, Luxurious, Cozy-styled & Large private KING Bed & Barn view one-bedroom in-law apt. (1,050 sqft) w/ Fireplace. On 2 Beautiful Acres under towering trees, while only being 3 min.(1 mi) to the Biltmore Estate. 5-min. (4 mi) to the Heart of Downtown Asheville, NC; Blue Ridge Parkway, & South Slope DT breweries, coffee houses, and restaurants. Romantic, Quiet, Retreat Cottage, Nestled in Nature. A unique gem, close to it all
Popular amenities for Upstate South Carolina house rentals
House rentals with a pool

Keowee Key Luxury Condo - Stunning Views!

Lakeside Family & Dog Retreat Awaits! DWC

Mountain home w/ hot tub & backyard

HOT TUB Sleeps 11 Gameroom Cozy Getaway

Pet + Family Friendly 4BR Pool House Near Furman

Wonderful mountain cottage with amazing view!

Shalom House with Pool near DT Greer SC

A quiet place in the country
Weekly house rentals

Modern Cottage in the Woods w/ Hot Tub & Firepit

Springs Cottage w/Outdoor Oasis - Cozy Backyard

Comfy Pelham Rd Gem | 1 Story | Kid & Dog Friendly

Cozy cottage condo close toTIEC,Hndrsvlle&Hospital

Relaxing Stay on Trade Street Near Downtown Greer

The Dogwoods Lower at Vineyard Gap

A cozy mountain cottage, the Byrd Box sleeps four!

Deluxe Downtown Bungalow, fenced yard!
Private house rentals

Waterfall Cove - Prime

Fairview Luxury Oasis

The Mountain House

Cozy 2-Bedroom Retreat, Sleeps 6, Luxe Shower

Grace Mountain Cottage-Mtn views /Peaceful+Private

Welcome to River House

LONG Range VIEWS! Modern/Chic, Close DT Hendo Fun

Cozy home in downtown TR
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- Blue Ridge Parkway
- The North Carolina Arboretum
- Gorges State Park
- Table Rock State Park
- Chimney Rock State Park
- Ski Sapphire Valley
- Lake Lure Beach and Water Park
- Jump Off Rock
- Tryon International Equestrian Center
- Wade Hampton Golf Club
- Victoria Valley Vineyards
- Discovery Island
- Haas Family Golf
- Carl Sandburg Home National Historic Site
- Burntshirt Vineyards
- City Scape Winery
- Saint Paul Mountain Vineyards
- Overmountain Vineyards
- Wellborn Winery
- Russian Chapel Hills Winery
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