
Guesthouse holiday rentals in Upstate South Carolina
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Top-rated Guesthouses in Upstate South Carolina
Guests agree: These guesthouses are highly rated for location, cleanliness and more.

Scenic Loft in the Woods
Come relax for a getaway in our elegant guest loft! Located near the end of a quiet road with lots of wide open fields and beautiful tree lines! Our loft features a cute kitchenette, plenty of closet space, TV(YoutubeTV & Roku), an extremely comfortable bed! The loft is kept very clean and neat and will be stocked with all the essentials. Access to a beautiful 33' above ground pool! We are conveniently located about 5 miles from downtown Abbeville, and only a 10 minute drive to Erskine/Due West!

The Cottage in Spartanburg
This charming & private studio cottage is located in Spartanburg's downtown historic district Hampton Heights. Guests will find a comfortable foam mattress sofa bed (no bars or springs), full bathroom, closet, & complete kitchen amenities. Located less than a mile from restaurants, bars, m-league ball park & shops of Downtown Spartanburg, and close to Converse Univ., VCOM, and Wofford College, this cozy studio cottage is the perfect place to rest your head after a busy day visiting the Upstate.

Historic 19th Century Cabin/Guest House
This 19th century cabin is your perfect cozy getaway. This guest house is located on a 3.5 acre property, secluded from the historic neighborhood, though it's just 3 miles from downtown Greenville and the Bon Secours Wellness Arena. Less than a mile to the Swamp Rabbit Trail, this cottage is perfect for jaunts to downtown Greenville, Furman University, Paris Mountain, Travelers Rest and Unity Park! Micro weddings and events are available upon request and approval with applicable fees applied.

The Cottage at Old Oaks Farm
Built in the early 1900's, this serene cottage is located approximately one mile from Furman University at the base of Paris Mt. It has been lovingly improved, but the floors are a bit slanted and no corner is exactly square. Located in a neighborhood on a five acre farm, it consists of three large rooms, comfortably furnished and lots of natural light. The cottage is convenient to downtown Greenville(5 miles),Travelers Rest, Furman, and the Swamp Rabbit Trail. No pet fee or cleaning fee.

La Bella Farm
Do you want to be close to Clemson(11 miles), Anderson(9 miles) OR Greenville(20miles)! Do you want to just get away from all of the noise and busy life. Then you have found your spot! This is a great detached garage apartment. Settled in the quiet country side of Pendleton SC. 1 bedroom&1 bathroom with an additional sofa bed&blow up mattress. Great view of nothing but beautiful land from the kitchen window yet minutes away from Death Valley,restaurants,shopping and 85.

Mountain Edge Loft
Private loft apartment on 25 wooded acres, sits separate from main farm house. Private deck overlooking the woods. Everything you need for a cozy stay. Located on the edge of the Blue Ridge Escarpment with lakes Jocassee and Keowee just a few miles away. Numerous state parks, hiking, biking , waterfalls and kayaking or just peace and quiet. We are a sustainable homestead with an organic garden, chickens ,quail, dogs and cats. Our water comes from a natural spring.

The Lodge at Pythian Park
Situated in a 3+ acre gated compound surrounded on three sides by Fairforest Creek, our guest house feels like a mountain hideaway yet it's only a 3 minute drive to downtown Spartanburg. Enjoy the private patio overlooking the creek to relax or prepare a meal on the gas grill. Dogs are welcome, and we have 2 very social dogs that you will probably encounter during your stay. There's ample parking for vehicles and room to roam and enjoy the park-like setting.

Greenville With A View!
ONLY 10-15 MINUTE DRIVE TO THE HEART OF BEAUTIFUL DOWNTOWN GREENVILLE! We are only 11 miles to GSP Airport; 6 miles to Greenville Downtown Airport; and 10 minutes to the Swamp Rabbit Trail. We are minutes to Furman University, Bob Jones University, North Greenville University and Clemson University is only 45 minutes away. We are tucked away open top of Paris Mountain. If you want to bike, hike, paddle, swim, boat or just soak it all in, start here!

Entire Cottage w/Hot Tub - Easy Checkout!
The Cozy Cottage is a stunning 600-square-foot space containing 1br and 1ba, walk-in closet, full kitchen, washer and dryer, dishwasher, and living space. We have several premium features including an adjustable climate control system for the queen bed (BedJet) and access to our hot tub in the nearby outdoor living space! There is a dedicated 2 car parking pad for our guests and excellent lighting from the parking area all the way to the cottage.

Foothills Favorite
Custom designed 1 bedroom suite in the Lake Bowen/Landrum/Inman area. Comfortable yet sleek space tucked above a semi-detached garage; private entry & stairway to suite. Private deck overlooks green spaces, wooded area & Lake Bowen (best views late fall and winter). Enjoy mountain views at nearby Lake Bowen park, local wineries, and scenic highways. Minutes from Landrum & Tryon & Equestrian Center.

Shou-Sugi-Ban Retreat on the Saluda River
The Shou-Sugi-Ban Guest House is 5 miles from Greenville city center and West Greenville, yet you'll feel like you've escaped it all with the rush of the river and surrounding trees. This cozy, custom space has a king-size bed, and two sets of French doors leading out to a private deck. No matter where you are in the space, you'll have views of the 700 ft of Saluda river frontage.

Sally's Cottage
Couples retreat located 6 miles from downtown Greenville and the Swamp Rabbit Trail in a comfortable country setting. Wake up to a beautiful woods view through a large bay window and wildlife that surrounds the cottage (deer, birds and squirrels). Experience the beauty of the country in the city! Enjoy the eclectic collection of art and design in this cute little cottage.
Popular amenities for Upstate South Carolina guesthouses
Family-Friendly guesthouses

Cozy Rustic Lakefront Cabin

Holly Hideaway! 10 Highway miles to Clemson U!

The Nest; private tiny home @Reblooming Rose

Bungalow on a 3 acre mini farm

Ol Skool Cabin ( tiny home)

Home on the farm

Lisa’s Lodge

Blessed Haven - king bed guest house
Guesthouses with a patio

Modern Studio near downtown

Yes please we need you! Spacious w/ amazing view!

Starswept Studio–Walk to Brewery, Near BRP & GSMNP

1 bedroom guest house on horse property in Tryon

Small & Cozy Downtown GVL Studio

Downtown guest house with private hot tub & deck

Restful Refuge

Cozy guest cottage at The Black Walnut Chateau
Guest house rentals with a washing machine and dryer

Upscale cottage in Downtown Fountain Inn

MeadowHill Guesthouse - Mountain view-3 mi to town

Great 1 BR house in Normaltown

⭐️⭐️⭐️⭐️⭐️Casita Blanca 🚶🏽➡️Dining, BREWS,SHOPS📍DTWN📍LUX

Private North Asheville Bungalow No Cleaning fees

Tryon Foothills Getaway - NC wineries! - TIEC

Lit'l Bit O' Heaven- Rocky Top Lodge

Private-Lake getaway-7 mile view from dock
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- Blue Ridge Parkway
- Gorges State Park
- The North Carolina Arboretum
- Table Rock State Park
- Chimney Rock State Park
- Ski Sapphire Valley
- Lake Lure Beach and Water Park
- Tryon International Equestrian Center
- Jump Off Rock
- Wade Hampton Golf Club
- Victoria Valley Vineyards
- Discovery Island
- Carl Sandburg Home National Historic Site
- Haas Family Golf
- Saint Paul Mountain Vineyards
- City Scape Winery
- Burntshirt Vineyards
- Overmountain Vineyards
- Wellborn Winery
- Russian Chapel Hills Winery
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